xenopus anatomy 2.0.8.obo.owl
type: Ontology
namespace-id-rule: * XAO:$sequence(7,4000,9999999)$
date: 18:09:2012 22:24
data-version: 2012-10-23
treat-xrefs-as-genus-differentia: AAO part_of NCBITaxon:8353
treat-xrefs-as-genus-differentia: CARO part_of NCBITaxon:8353
treat-xrefs-as-genus-differentia: CL part_of NCBITaxon:8353
auto-generated-by: OBO-Edit 2.1-beta13
remark: Original XAO drafted by E Segerdell, JB Bowes, N Pollet, and PD Vize BMC Dev Biol. 2008 Sep 25;p.8-92 (PMID:18817563)
treat-xrefs-as-genus-differentia: UBERON part_of NCBITaxon:8353
treat-xrefs-as-genus-differentia: VSAO part_of NCBITaxon:8353
remark: XAO v2.0.8 updated by Xenbase: VG Ponferrada, EJ Segerdell, CH James-Zorn, KA Burns, JD Fortriede, W Dahdul Oct 2012
remark: supported by NIH R01 HD045776 and NICHD P41 HD064556
saved-by: xenbase
default-namespace: xenopus_anatomy
remark: 2012-10-23

PLURAL
type: AnnotationProperty
sub property of: synonym_type_property

in_subset
type: AnnotationProperty

term replaced by
type: AnnotationProperty

definition
type: AnnotationProperty

has_synonym_type
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

anatomical site slim
type: AnnotationProperty
comment: Anatomical Site slim
sub property of: subset_property

has_alternative_id
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

frequent anatomy items
type: AnnotationProperty
comment: Frequently Used Anatomy slim
sub property of: subset_property

sectional anatomy items
type: AnnotationProperty
comment: Sectional Anatomy Item slim
sub property of: subset_property

subset_property
type: AnnotationProperty

synonym_type_property
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

organism views
type: AnnotationProperty
comment: Organism View slim
sub property of: subset_property

consider
type: AnnotationProperty

treat-xrefs-as-genus-differentia
type: AnnotationProperty

has_broad_synonym
type: AnnotationProperty

develops from
type: ObjectProperty
type: TransitiveProperty
id: develops_from

ends during
type: ObjectProperty
definition: Anatomical structure/expression stops being viable, obvious or of utility during this developmental stage.
id: end_stage

Axiom
annotated target: Anatomical structure/expression stops being viable, obvious or of utility during this developmental stage.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: ends during

part of
type: ObjectProperty
type: TransitiveProperty
id: part_of

preceded by
type: ObjectProperty
type: TransitiveProperty
id: preceded_by

starts during
type: ObjectProperty
definition: Anatomical structure/expression begins being viable, obvious or of utility during this developmental stage.
id: start_stage

Axiom
annotated target: Anatomical structure/expression begins being viable, obvious or of utility during this developmental stage.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: starts during

Xenopus anatomical entity
type: Class
id: XAO:0000000

ectoderm
type: Class
subclass of: primary germ layer
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
database_cross_reference: AAO:0000137
definition: Primary germ layer that is the outer of the embryo's germ layers and gives rise to epidermis and neural tissue.
id: XAO:0000001
in_subset: frequent anatomy items

Axiom
database_cross_reference: OMD:ectoderm
annotated target: Primary germ layer that is the outer of the embryo's germ layers and gives rise to epidermis and neural tissue.
annotated property: definition
annotated source: ectoderm

fin
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: part of
  some values from: ectoderm
database_cross_reference: AAO:0010374
definition: Surface structure that has an important role in tadpole locomotion. It starts to develop along the trunk and tail of the embryo at the tail bud stage and continues to grow until the start of metamorphosis when it begins to regress. It consists of flattened epidermal cells elevated into a keel-like structure by a supporting core of mesenchyme and extracellular matrix.
id: XAO:0000002
in_subset: frequent anatomy items

Axiom
database_cross_reference: PMID:15188431
annotated target: Surface structure that has an important role in tadpole locomotion. It starts to develop along the trunk and tail of the embryo at the tail bud stage and continues to grow until the start of metamorphosis when it begins to regress. It consists of flattened epidermal cells elevated into a keel-like structure by a supporting core of mesenchyme and extracellular matrix.
annotated property: definition
annotated source: fin

outer fin
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: fin
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0010380
definition: Part of the fin consisting of flattened epidermal cells elevated into a keel-like structure.
id: XAO:0000003

Axiom
database_cross_reference: PMID:15188431
annotated target: Part of the fin consisting of flattened epidermal cells elevated into a keel-like structure.
annotated property: definition
annotated source: outer fin

inner fin
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: part of
  some values from: fin
database_cross_reference: AAO:0010379
definition: Part of the fin consisting of a supporting core of mesenchyme and extracellular matrix.
id: XAO:0000004

Axiom
database_cross_reference: PMID:15188431
annotated target: Part of the fin consisting of a supporting core of mesenchyme and extracellular matrix.
annotated property: definition
annotated source: inner fin

olfactory placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: develops from
  some values from: anterior neural ridge
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000054
subclass of: Restriction
  on property: develops from
  some values from: epidermis inner layer
subclass of: Restriction
  on property: part of
  some values from: olfactory system
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
definition: A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity.
database_cross_reference: AAO:0011076
id: XAO:0000005
has_related_synonym: nasal placode

Axiom
annotated target: A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity.
database_cross_reference: NLM:olfactory+placode
annotated property: definition
annotated source: olfactory placode

otic vesicle
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000070
subclass of: Restriction
  on property: develops from
  some values from: otic placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: part of
  some values from: vestibuloauditory system
database_cross_reference: AAO:0011080
definition: The saccular invagination of ectoderm from which the vertebrate inner ear develops.
id: XAO:0000006
has_alternative_id: XAO:0000184
has_broad_synonym: ear
has_related_synonym: ear vesicle
in_subset: frequent anatomy items

Axiom
annotated target: The saccular invagination of ectoderm from which the vertebrate inner ear develops.
database_cross_reference: UBERON:0003051
annotated property: definition
annotated source: otic vesicle

lower eyelid
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000074
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A surface structure consisting of a set of membranes that cover and protect the eye.
database_cross_reference: AAO:0010349
id: XAO:0000007

Axiom
annotated target: A surface structure consisting of a set of membranes that cover and protect the eye.
database_cross_reference: http://en.wikipedia.org/wiki/Frog
annotated property: definition
annotated source: lower eyelid

lens
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: develops from
  some values from: lens placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010348
definition: Transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina.
id: XAO:0000008

Axiom
annotated target: Transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina.
database_cross_reference: WIKI:Lens_(anatomy)
annotated property: definition
annotated source: lens

retina
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010352
definition: Sensory membrane that lines the posterior chamber of the eye and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve.
id: XAO:0000009

Axiom
database_cross_reference: NLM:retina
annotated target: Sensory membrane that lines the posterior chamber of the eye and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve.
annotated property: definition
annotated source: retina

brain
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: part of
  some values from: central nervous system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
database_cross_reference: AAO:0010478
definition: Organ that is a component of the central nervous system and is responsible for the coordination and control of bodily activities and the interpretation of information from the senses. It appears when the neural tube segregates in forebrain, midbrain, and hindbrain at NF stage 22. The general pattern of the brain has been mainly established at NF stage 28. Yolky material is consumed and the fibre tracts and later the commissures develop. In general all of its parts are well developed at NF stage 53 and later development consists mainly of growth and some further cytological differentiation. In the period of metamorphosis only topographical changes take place.
id: XAO:0000010
in_subset: frequent anatomy items

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: OMD:brain
annotated target: Organ that is a component of the central nervous system and is responsible for the coordination and control of bodily activities and the interpretation of information from the senses. It appears when the neural tube segregates in forebrain, midbrain, and hindbrain at NF stage 22. The general pattern of the brain has been mainly established at NF stage 28. Yolky material is consumed and the fibre tracts and later the commissures develop. In general all of its parts are well developed at NF stage 53 and later development consists mainly of growth and some further cytological differentiation. In the period of metamorphosis only topographical changes take place.
annotated property: definition
annotated source: brain

forebrain
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: brain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: anterior neural tube
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010147
definition: The part of the brain that is the anterior of its three primary divisions and that includes the telencephalon and diencephalon.
id: XAO:0000011
has_related_synonym: prosencephalon

Axiom
database_cross_reference: NLM:forebrain
annotated target: The part of the brain that is the anterior of its three primary divisions and that includes the telencephalon and diencephalon.
annotated property: definition
annotated source: forebrain

telencephalon
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: forebrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010479
definition: Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres.
id: XAO:0000012

Axiom
database_cross_reference: AAO:0010479
annotated target: Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres.
annotated property: definition
annotated source: telencephalon

diencephalon
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: forebrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010481
definition: The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye vescile, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis).
id: XAO:0000013

Axiom
annotated target: The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye vescile, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis).
database_cross_reference: XAO:curator
annotated property: definition
annotated source: diencephalon

midbrain
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: anterior neural tube
subclass of: Restriction
  on property: part of
  some values from: brain
database_cross_reference: AAO:0010149
definition: Middle part of the brain composed of the optic tectum and penducular region.
id: XAO:0000014
has_related_synonym: mesencephalon

Axiom
database_cross_reference: AAO:0010149
annotated target: Middle part of the brain composed of the optic tectum and penducular region.
annotated property: definition
annotated source: midbrain

hindbrain
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: develops from
  some values from: posterior neural tube
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: brain
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010150
definition: The part of the brain that is the posterior of its three primary divisions.
id: XAO:0000015
has_related_synonym: rhombencephalon

Axiom
database_cross_reference: NLM:hindbrain
annotated target: The part of the brain that is the posterior of its three primary divisions.
annotated property: definition
annotated source: hindbrain

midbrain-hindbrain boundary
type: Class
subclass of: anatomical line
subclass of: Restriction
  on property: develops from
  some values from: presumptive midbrain-hindbrain boundary
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: brain
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: neural plate
database_cross_reference: AAO:0011064
has_exact_synonym: MHB
definition: The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate.
id: XAO:0000016
has_related_synonym: isthmic organizer territory
has_related_synonym: isthmus

Axiom
database_cross_reference: GO:0021555
annotated target: The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate.
annotated property: definition
annotated source: midbrain-hindbrain boundary

hypophysis
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: hypophyseal primordium
subclass of: Restriction
  on property: develops from
  some values from: adenohypophyseal placode
subclass of: Restriction
  on property: part of
  some values from: forebrain
subclass of: Restriction
  on property: part of
  some values from: endocrine system
definition: An endocrine gland, located ventral to the diencephalon, that secretes hormones that regulate many other glands.
id: XAO:0000017
has_alternative_id: XAO:0000161
database_cross_reference: ZFA:0000118
has_related_synonym: pituitary
has_related_synonym: pituitary gland

Axiom
annotated target: An endocrine gland, located ventral to the diencephalon, that secretes hormones that regulate many other glands.
database_cross_reference: UBERON:0000007
annotated property: definition
annotated source: hypophysis

genital ridge
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000064
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
database_cross_reference: AAO:0011047
definition: Portion of tissue that is the precursor to the gonads.
id: XAO:0000018

Axiom
annotated target: Portion of tissue that is the precursor to the gonads.
database_cross_reference: WIKI:Gonadal_ridge
annotated property: definition
annotated source: genital ridge

spinal cord
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: posterior neural tube
subclass of: Restriction
  on property: part of
  some values from: central nervous system
database_cross_reference: AAO:0010151
definition: Elongated, approximately cylindrical part of the central nervous system that lies in the vertebral canal and from which the spinal nerves emerge.
id: XAO:0000020

Axiom
annotated target: Elongated, approximately cylindrical part of the central nervous system that lies in the vertebral canal and from which the spinal nerves emerge.
database_cross_reference: OMD:spinal+cord
annotated property: definition
annotated source: spinal cord

ventricular zone
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: brain
database_cross_reference: AAO:0011112
definition: Proliferative region that is part of the ventricular system of the brain.
id: XAO:0000021
in_subset: anatomical site slim

Axiom
annotated target: Proliferative region that is part of the ventricular system of the brain.
database_cross_reference: VHOG:0001224
annotated property: definition
annotated source: ventricular zone

roof plate
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: spinal cord
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0011097
definition: Organizing center located at the dorsal midline of the neural tube that influences the development of the nervous system, controlling the specification and differentiation of dorsal neuronal cell types.
id: XAO:0000022
has_exact_synonym: roofplate
has_related_synonym: spinal cord roof

Axiom
annotated target: Organizing center located at the dorsal midline of the neural tube that influences the development of the nervous system, controlling the specification and differentiation of dorsal neuronal cell types.
database_cross_reference: PMID:15378040
annotated property: definition
annotated source: roof plate

skin
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: dermal system
database_cross_reference: AAO:0000239
definition: Surface structure that consists of the external membranous integument of the animal.
id: XAO:0000023
has_related_synonym: integument

Axiom
database_cross_reference: OMD:skin
annotated target: Surface structure that consists of the external membranous integument of the animal.
annotated property: definition
annotated source: skin

mandibular crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: develops from
  some values from: cranial neural crest
subclass of: Restriction
  on property: part of
  some values from: cranial neural crest
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
definition: The most anterior of the migrating cranial neural crest streams, running along the posterior edge of the eye primordium, and in later stages, below the eye and to the border of the cement gland. The mandibular stream is the first to initiate CNC cell migration.
id: XAO:0000024

Axiom
database_cross_reference: PMID:21490068
annotated target: The most anterior of the migrating cranial neural crest streams, running along the posterior edge of the eye primordium, and in later stages, below the eye and to the border of the cement gland. The mandibular stream is the first to initiate CNC cell migration.
annotated property: definition
annotated source: mandibular crest

hyoid crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: develops from
  some values from: cranial neural crest
definition: The second most anterior of the migrating cranial neural crests streams, hyoid crest lays between the mandibular and anterior branchial crest streams.
id: XAO:0000025
database_cross_reference: ZFA:0007065
has_exact_synonym: hyoid neural crest

Axiom
database_cross_reference: PMID:21490068
annotated target: The second most anterior of the migrating cranial neural crests streams, hyoid crest lays between the mandibular and anterior branchial crest streams.
annotated property: definition
annotated source: hyoid crest

branchial crest
type: Class
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: cranial neural crest
subclass of: Restriction
  on property: develops from
  some values from: cranial neural crest
definition: The most posterior segments of the population of migratory cells of the cranial neural crest, contributing to the branchial arches 3 and 4. Branchial crest cells migrate in two distinct streams referred to as the anterior and posterior branchial crest.
id: XAO:0000026

Axiom
annotated target: The most posterior segments of the population of migratory cells of the cranial neural crest, contributing to the branchial arches 3 and 4. Branchial crest cells migrate in two distinct streams referred to as the anterior and posterior branchial crest.
database_cross_reference: XAO:CJZ
annotated property: definition
annotated source: branchial crest

cranial ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer of neurectoderm
definition: Ganglion that is located in the head.
id: XAO:0000027
database_cross_reference: ZFA:0000013
has_related_synonym: cranial ganglia

Axiom
annotated target: cranial ganglia
annotated source: cranial ganglion
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Ganglion that is located in the head.
database_cross_reference: ZFA:0000013
annotated property: definition
annotated source: cranial ganglion

epidermis
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: part of
  some values from: skin
subclass of: Restriction
  on property: part of
  some values from: ectoderm
database_cross_reference: AAO:0000143
definition: The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.
id: XAO:0000028
has_broad_synonym: skin
in_subset: frequent anatomy items

Axiom
database_cross_reference: AAO:0000143
annotated target: The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.
annotated property: definition
annotated source: epidermis

epidermis outer layer
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: epidermis
definition: The outermost layer of the epidermis, the multilayered epithelium derived from the ectoderm.
id: XAO:0000029
database_cross_reference: ZFA:0001185
has_related_synonym: epidermis epithelial layer
has_related_synonym: periderm

Axiom
annotated target: The outermost layer of the epidermis, the multilayered epithelium derived from the ectoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: epidermis outer layer

vitelline membrane
type: Class
subclass of: extraembryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000001
subclass of: Restriction
  on property: part of
  some values from: zygote
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000092
database_cross_reference: AAO:0010332
definition: Thin membrane enclosing and immediately adjacent to the ovum. Produced in the ovary. The membrane enveloping the egg or oocyte; lies immediately outside the plasmalemma; formed while the oocyte is in the ovary; separates from the egg to form the fertilization membrane.
id: XAO:0000030

Axiom
database_cross_reference: AAO:0010332
annotated target: Thin membrane enclosing and immediately adjacent to the ovum. Produced in the ovary. The membrane enveloping the egg or oocyte; lies immediately outside the plasmalemma; formed while the oocyte is in the ovary; separates from the egg to form the fertilization membrane.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: vitelline membrane

ciliated epidermal cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: epidermis
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
definition: Cell type that has motile cilia and populates the skin of the embryo, arranged in the surface layer of the non-neural ectoderm in an ordered distribution.
id: XAO:0000031
has_broad_synonym: ciliated cell

Axiom
annotated target: Cell type that has motile cilia and populates the skin of the embryo, arranged in the surface layer of the non-neural ectoderm in an ordered distribution.
database_cross_reference: PMID:10518489
annotated property: definition
annotated source: ciliated epidermal cell

stomodeal-hypophyseal primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: An anterior thickening of the sensorial layer of ectoderm, just above the cement gland. The hypophyseal layer separates from the stomodeal layer at NF stage 29 and 30, and when contacted by a protrusion of the foregut, the stomodeal layer will rupture to form the mouth opening at NF stage 39 and 40.
id: XAO:0000032

Axiom
annotated target: An anterior thickening of the sensorial layer of ectoderm, just above the cement gland. The hypophyseal layer separates from the stomodeal layer at NF stage 29 and 30, and when contacted by a protrusion of the foregut, the stomodeal layer will rupture to form the mouth opening at NF stage 39 and 40.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: stomodeal-hypophyseal primordium

cement gland
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000062
subclass of: Restriction
  on property: develops from
  some values from: cement gland primordium
definition: A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm.
database_cross_reference: AAO:0010373
id: XAO:0000033
in_subset: frequent anatomy items

Axiom
annotated target: A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm.
database_cross_reference: PMID:8787748
annotated property: definition
annotated source: cement gland

hatching gland
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: XAO_0004394
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000049
definition: A Y-shaped array of unicelluar glands on the top of a head, the open end of the Y faces anteriorly, that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching. Presumptive cells of the hatching gland are present by the end of gastrualtion ( NF stage 12.5) and differentiated cells start to form after neurulation is complete (NF stage 21).
database_cross_reference: AAO:0011050
id: XAO:0000034
has_related_synonym: frontal gland

Axiom
annotated target: A Y-shaped array of unicelluar glands on the top of a head, the open end of the Y faces anteriorly, that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching. Presumptive cells of the hatching gland are present by the end of gastrualtion ( NF stage 12.5) and differentiated cells start to form after neurulation is complete (NF stage 21).
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hatching gland

zygote
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000001
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: CL:0000365
definition: Cell resulting from the fusion of male and female gametes at fertilization.
id: XAO:0000035
has_exact_synonym: fertilized egg

Axiom
annotated target: Cell resulting from the fusion of male and female gametes at fertilization.
database_cross_reference: OMD:zygote
annotated property: definition
annotated source: zygote

animal cap
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000016
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
database_cross_reference: AAO:0010463
definition: Ectodermal roof of the blastocoel.
id: XAO:0000036
has_related_synonym: animal ectoderm

Axiom
annotated target: Ectodermal roof of the blastocoel.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: animal cap

animal cap inner layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: animal cap
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
database_cross_reference: AAO:0010464
definition: Sensorial layer of blastocoel roof ectoderm.
id: XAO:0000037

Axiom
annotated target: Sensorial layer of blastocoel roof ectoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: animal cap inner layer

animal cap outer layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: animal cap
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
database_cross_reference: AAO:0010465
definition: Superficial layer of blastocoel roof ectoderm.
id: XAO:0000038

Axiom
annotated target: Superficial layer of blastocoel roof ectoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: animal cap outer layer

anatomical site
type: Class
id: XAO:0000039
consider: XAO:0003186
deprecated: true

head region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
definition: The anterior most third of the embryo, from the development of the head outgrowth at NF stage 21.
id: XAO:0000040
in_subset: anatomical site slim

Axiom
annotated target: The anterior most third of the embryo, from the development of the head outgrowth at NF stage 21.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head region

epidermis inner layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: part of
  some values from: epidermis
definition: A distinct layer of the epidermal cells beneath the outermost layer of epidermis, the multilayered epithelium derived from the ectoderm.
id: XAO:0000041
has_related_synonym: epidermis sensorial layer
has_related_synonym: stratum germinativum

Axiom
annotated target: A distinct layer of the epidermal cells beneath the outermost layer of epidermis, the multilayered epithelium derived from the ectoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: epidermis inner layer

neuroectoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
database_cross_reference: AAO:0011074
definition: Embryonic ectoderm that gives rise to nervous tissue.
id: XAO:0000042
has_related_synonym: neural ectoderm
has_exact_synonym: neurectoderm
has_related_synonym: presumptive central nervous system

Axiom
annotated target: Embryonic ectoderm that gives rise to nervous tissue.
database_cross_reference: NLM:neuroectoderm
annotated property: definition
annotated source: neuroectoderm

neuroectoderm outer layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: Superficial neuroectoderm layer consisting of horizontally flattened, pigmented cells.
id: XAO:0000043

Axiom
database_cross_reference: PMID:2642003
annotated target: Superficial neuroectoderm layer consisting of horizontally flattened, pigmented cells.
annotated property: definition
annotated source: neuroectoderm outer layer

neuroectoderm inner layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
definition: Deep neuroectoderm layer consisting of densely packed, cylindrical, unpigmented cells.
id: XAO:0000044

Axiom
annotated target: Deep neuroectoderm layer consisting of densely packed, cylindrical, unpigmented cells.
database_cross_reference: PMID:2642003
annotated property: definition
annotated source: neuroectoderm inner layer

pre-chordal neural plate
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: neural plate
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
database_cross_reference: AAO:0011084
definition: The portion of neural plate anterior to the mid-hindbrain junction.
id: XAO:0000045
has_related_synonym: anterior neural plate

Axiom
annotated target: The portion of neural plate anterior to the mid-hindbrain junction.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: pre-chordal neural plate

chordal neural plate
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: neural plate
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
definition: The portion of neural plate posterior to the mid-hindbrain junction.
id: XAO:0000046
has_related_synonym: posterior neural plate

Axiom
annotated target: The portion of neural plate posterior to the mid-hindbrain junction.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: chordal neural plate

notoplate
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: neural plate
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000033
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
definition: Region of the neural plate overlying the notochord.
id: XAO:0000047

Axiom
annotated target: Region of the neural plate overlying the notochord.
database_cross_reference: http://www.encyclo.co.uk/define/Notoplate
annotated property: definition
annotated source: notoplate

neural crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
definition: A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchemal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem-cell like.
database_cross_reference: AAO:0010578
has_exact_synonym: NC
id: XAO:0000048
has_related_synonym: neural crest material
in_subset: frequent anatomy items

Axiom
annotated target: A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchemal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem-cell like.
database_cross_reference: AAO:0010578
database_cross_reference: XAO:CJZ
annotated property: definition
annotated source: neural crest

cement gland primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
definition: The thickening of the epithelial layer of the ectoderm, with corresponding dark pigmentation, on the anterior dorso-ventral surface of the embryo.
id: XAO:0000049
has_exact_synonym: adhesive organ primordium
has_broad_synonym: cement gland
has_exact_synonym: cement gland anlage

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The thickening of the epithelial layer of the ectoderm, with corresponding dark pigmentation, on the anterior dorso-ventral surface of the embryo.
annotated property: definition
annotated source: cement gland primordium

mesoderm
type: Class
subclass of: primary germ layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0000304
definition: Primary germ layer that is the middle of the embryo's germ layers.
id: XAO:0000050
has_related_synonym: mesodermal mantle
in_subset: frequent anatomy items

Axiom
database_cross_reference: OMD:mesoderm
annotated target: Primary germ layer that is the middle of the embryo's germ layers.
annotated property: definition
annotated source: mesoderm

dorsal aorta
type: Class
subclass of: aorta
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: develops from
  some values from: arterial endothelium
database_cross_reference: AAO:0011029
definition: Principal unpaired, median artery of the trunk, extending into the tail as the caudal artery.
id: XAO:0000051
has_exact_synonym: aorta dorsalis

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: Principal unpaired, median artery of the trunk, extending into the tail as the caudal artery.
annotated property: definition
annotated source: dorsal aorta

cardinal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
database_cross_reference: AAO:0011022
definition: The paired main vein, departing from the sinus venous, the fused heart primordium, it runs posteriorly down length of the embryo.
id: XAO:0000052

Axiom
annotated target: The paired main vein, departing from the sinus venous, the fused heart primordium, it runs posteriorly down length of the embryo.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cardinal vein

head mesoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: develops from
  some values from: prechordal plate
database_cross_reference: AAO:0011051
definition: The mesoderm of the head.
id: XAO:0000053

Axiom
annotated target: The mesoderm of the head.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head mesoderm

trunk region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: ends during
  some values from: death
definition: The anatomical region of the body posterior to the head and anterior to the tail.
id: XAO:0000054
in_subset: anatomical site slim

Axiom
annotated target: The anatomical region of the body posterior to the head and anterior to the tail.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk region

notochord
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000033
subclass of: Restriction
  on property: develops from
  some values from: axial mesoderm
definition: A longitudinal flexible rod of cells that in the embryo forms the supporting axis of the body. It degenerates, beginning anteriorly, at NF stage 46. Its posterior portion is greatly reduced by NF stage 55 and the entire structure is gone by NF stage 65.
database_cross_reference: VSAO:0000032
id: XAO:0000055
in_subset: frequent anatomy items

Axiom
annotated target: A longitudinal flexible rod of cells that in the embryo forms the supporting axis of the body. It degenerates, beginning anteriorly, at NF stage 46. Its posterior portion is greatly reduced by NF stage 55 and the entire structure is gone by NF stage 65.
database_cross_reference: ISBN:0815318960
database_cross_reference: NLM:notochord
annotated property: definition
annotated source: notochord

hypochord
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: endoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000055
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: develops from
  some values from: endoderm
database_cross_reference: AAO:0000733
definition: Transient structure that lies immediately ventral to the notochord in the embryo, likely required for the formation of the dorsal aorta. A slight depression marks the future hypochord at NF stage 20 and its segregation from the dorsal endoderm begins at NF stage 24. It progresses from anterior to posterior and is complete by NF stage 28. At NF stage 32 it is present as a dorso-laterally flattened ribbon of yolk-laden cells. It degenerates by apoptosis and by NF stage 43 is no longer detectable as a distinct structure.
id: XAO:0000056
has_exact_synonym: ipochord
has_related_synonym: subnotochordal rod

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: PMID:10648245
annotated target: Transient structure that lies immediately ventral to the notochord in the embryo, likely required for the formation of the dorsal aorta. A slight depression marks the future hypochord at NF stage 20 and its segregation from the dorsal endoderm begins at NF stage 24. It progresses from anterior to posterior and is complete by NF stage 28. At NF stage 32 it is present as a dorso-laterally flattened ribbon of yolk-laden cells. It degenerates by apoptosis and by NF stage 43 is no longer detectable as a distinct structure.
annotated property: definition
annotated source: hypochord

Axiom
database_cross_reference: PMID:10648245
annotated target: subnotochordal rod
annotated source: hypochord
annotated property: has_related_synonym

presomitic mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: paraxial mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: develops from
  some values from: paraxial mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
database_cross_reference: AAO:0011086
definition: Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form.
id: XAO:0000057
has_related_synonym: somitogenic mesoderm

Axiom
database_cross_reference: UBERON:0003059
annotated target: Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form.
annotated property: definition
annotated source: presomitic mesoderm

somite
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
database_cross_reference: AAO:0010569
definition: Any of the approximately 45 bilaterally paired blocks of mesoderm cells, lying on either side of the notochord and neural tube, and forming sequentially starting at the head during development of the embryo. Together they give rise to the axial skeleton (from the sclerotome), associated musculature (from the myotome), and dermis (from the dermatome).
id: XAO:0000058
has_related_synonym: somites
has_related_synonym: somitic mesoderm
in_subset: frequent anatomy items

Axiom
annotated target: somites
annotated source: somite
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Any of the approximately 45 bilaterally paired blocks of mesoderm cells, lying on either side of the notochord and neural tube, and forming sequentially starting at the head during development of the embryo. Together they give rise to the axial skeleton (from the sclerotome), associated musculature (from the myotome), and dermis (from the dermatome).
database_cross_reference: OMD:somite
database_cross_reference: XAO:curator
annotated property: definition
annotated source: somite

pronephros
type: Class
id: XAO:0000059
term replaced by: XAO:0002000
deprecated: true

pronephric capsule
type: Class
id: XAO:0000061
consider: XAO:0000318
deprecated: true

nephrostome
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: pronephric mesenchyme
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000071
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: pronephric kidney
database_cross_reference: AAO:0011069
definition: The opening of the pronephros into the body cavity.
id: XAO:0000062

Axiom
database_cross_reference: GO:0039018
annotated target: The opening of the pronephros into the body cavity.
annotated property: definition
annotated source: nephrostome

pronephric duct
type: Class
subclass of: duct
subclass of: Restriction
  on property: part of
  some values from: pronephric kidney
subclass of: Restriction
  on property: develops from
  some values from: pronephric mesenchyme
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000067
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
database_cross_reference: AAO:0011088
definition: Duct which drains the pronephros and connects it to the cloaca.
has_exact_synonym: Wolffian duct
id: XAO:0000063
has_exact_synonym: connecting tubule
has_exact_synonym: nephric duct

Axiom
annotated target: Duct which drains the pronephros and connects it to the cloaca.
database_cross_reference: PMID:8365571
annotated property: definition
annotated source: pronephric duct

heart
type: Class
subclass of: viscus
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: develops from
  some values from: fused heart primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010210
definition: Internal, blood-pumping circulatory system organ ultimately composed of three chambers (two atria and one ventricle) and occupying a ventral position within the chest of the mature tadpole/frog.
id: XAO:0000064
in_subset: frequent anatomy items

Axiom
database_cross_reference: AAO:0010210
annotated target: Internal, blood-pumping circulatory system organ ultimately composed of three chambers (two atria and one ventricle) and occupying a ventral position within the chest of the mature tadpole/frog.
database_cross_reference: PMID:17194606
annotated property: definition
annotated source: heart

myocardium
type: Class
subclass of: muscle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: develops from
  some values from: fused heart primordium
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010410
definition: The middle layer of the heart, consisting of cardiac muscle.
id: XAO:0000065
has_related_synonym: cardiac muscle

Axiom
database_cross_reference: AAO:0010410
annotated target: The middle layer of the heart, consisting of cardiac muscle.
annotated property: definition
annotated source: myocardium

endocardium
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: develops from
  some values from: fused heart primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010408
definition: Part of the heart composed of thin serous membrane and endothelial tissue, that lines the interior of the heart.
id: XAO:0000066

Axiom
database_cross_reference: AAO:0010408
annotated target: Part of the heart composed of thin serous membrane and endothelial tissue, that lines the interior of the heart.
annotated property: definition
annotated source: endocardium

ventral blood island
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: develops from
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000049
database_cross_reference: AAO:0011006
definition: Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.
has_exact_synonym: VBI
id: XAO:0000067
has_broad_synonym: blood island
has_broad_synonym: ventral lateral plate mesoderm

Axiom
database_cross_reference: PMID:9618755
annotated target: Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.
annotated property: definition
annotated source: ventral blood island

marginal zone
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: AAO:0010448
definition: Region of intermediate pigmentation between the pigmented animal hemisphere and the unpigmented vegetal hemisphere of the egg.
id: XAO:0000068

Axiom
annotated target: Region of intermediate pigmentation between the pigmented animal hemisphere and the unpigmented vegetal hemisphere of the egg.
database_cross_reference: http://worms.zoology.wisc.edu/frogs/glossary.html
annotated property: definition
annotated source: marginal zone

ventral marginal zone
type: Class
subclass of: marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
database_cross_reference: AAO:0010453
definition: Embryonic tissue region that will make the ventral mesoderm.
has_exact_synonym: VMZ
id: XAO:0000069

Axiom
annotated target: Embryonic tissue region that will make the ventral mesoderm.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ventral marginal zone

ventro-lateral marginal zone
type: Class
subclass of: marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
database_cross_reference: AAO:0010454
definition: Region of the marginal zone extending from the ventral to lateral surface.
id: XAO:0000070

Axiom
annotated target: Region of the marginal zone extending from the ventral to lateral surface.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ventro-lateral marginal zone

dorso-lateral marginal zone
type: Class
subclass of: marginal zone
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: AAO:0010450
definition: Region of the marginal zone extending from the dorsal to lateral surface.
id: XAO:0000071

Axiom
annotated target: Region of the marginal zone extending from the dorsal to lateral surface.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: dorso-lateral marginal zone

dorsal marginal zone
type: Class
subclass of: marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
database_cross_reference: AAO:0010449
has_exact_synonym: DMZ
definition: Marginal zone that is a key embryonic tissue region of the early gastrula stage embryo and that houses the Spemann-Mangold organizer.
has_related_synonym: Spemann organizer
id: XAO:0000072
has_related_synonym: organizer

Axiom
annotated target: Marginal zone that is a key embryonic tissue region of the early gastrula stage embryo and that houses the Spemann-Mangold organizer.
database_cross_reference: PMID:17368611
annotated property: definition
annotated source: dorsal marginal zone

Axiom
annotated target: DMZ
database_cross_reference: PMID:17368611
annotated source: dorsal marginal zone
annotated property: has_exact_synonym

deep (mesenchymal) layer
type: Class
id: XAO:0000073
deprecated: true

involuting marginal zone
type: Class
subclass of: marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
database_cross_reference: AAO:0010451
has_exact_synonym: IMZ
definition: Portion of the marginal zone of the embryo that turns inside the embryo during involution.
id: XAO:0000074

Axiom
annotated target: Portion of the marginal zone of the embryo that turns inside the embryo during involution.
database_cross_reference: http://worms.zoology.wisc.edu/frogs/glossary.html
annotated property: definition
annotated source: involuting marginal zone

involuting marginal zone mesenchymal layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: involuting marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
definition: Deep layers of the IMZ consisting of prospective migrating mesodermal cells (which will migrate into the interior and form the leading edge of the mesodermal mantle) and prospective converging and extending mesoderm.
id: XAO:0000075
has_related_synonym: deep involuting marginal zone

Axiom
annotated target: Deep layers of the IMZ consisting of prospective migrating mesodermal cells (which will migrate into the interior and form the leading edge of the mesodermal mantle) and prospective converging and extending mesoderm.
database_cross_reference: ISBN:0123646200
annotated property: definition
annotated source: involuting marginal zone mesenchymal layer

involuting marginal zone epithelial layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: involuting marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
definition: Layer of prospective endoderm in the IMZ that will form the roof of the archenteron.
id: XAO:0000076
has_related_synonym: superficial involuting marginal zone

Axiom
database_cross_reference: ISBN:0123646200
annotated target: Layer of prospective endoderm in the IMZ that will form the roof of the archenteron.
annotated property: definition
annotated source: involuting marginal zone epithelial layer

bottle cell
type: Class
subclass of: gastrula cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000033
definition: Cell type that is first to migrate inwards at the blastopore during gastrulation.
id: XAO:0000077

Axiom
annotated target: Cell type that is first to migrate inwards at the blastopore during gastrulation.
database_cross_reference: OMD:bottle+cell
annotated property: definition
annotated source: bottle cell

blastopore lip
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000030
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: blastopore
database_cross_reference: AAO:0010455
definition: The edge of the blastopore. Local invagination is caused by narrowing of bottle cells at the exterior edge of the blastula.
id: XAO:0000078

Axiom
database_cross_reference: ISBN:0-387-53740-6
annotated target: The edge of the blastopore. Local invagination is caused by narrowing of bottle cells at the exterior edge of the blastula.
annotated property: definition
annotated source: blastopore lip

prechordal plate
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: axial mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000030
database_cross_reference: AAO:0011085
definition: Mesodermal structure that lies anterior to the notochord and gives rise to head mesoderm.
id: XAO:0000079
has_broad_synonym: head mesoderm

Axiom
annotated target: Mesodermal structure that lies anterior to the notochord and gives rise to head mesoderm.
database_cross_reference: VHOG:0000086
annotated property: definition
annotated source: prechordal plate

forelimb region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
definition: The region from which the forelimb develops, first recognizable at NF stage 48, and distinct by NF stage 49.
id: XAO:0000080
has_exact_synonym: fore limb region
in_subset: anatomical site slim

Axiom
annotated target: The region from which the forelimb develops, first recognizable at NF stage 48, and distinct by NF stage 49.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: forelimb region

hindlimb region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
definition: The region from which the hindlimb develops, first recognizable as a slight concentration of mesenchymal cells dorsal and lateral to the anal tube at NF stage 43. The epidermal layers thicken dramatically through to NF stage 48, and become vascularised by NF stage 49.
id: XAO:0000081
has_exact_synonym: hind limb region
in_subset: anatomical site slim

Axiom
annotated target: The region from which the hindlimb develops, first recognizable as a slight concentration of mesenchymal cells dorsal and lateral to the anal tube at NF stage 43. The epidermal layers thicken dramatically through to NF stage 48, and become vascularised by NF stage 49.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hindlimb region

circumblastoporal collar
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000039
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: Embryonic structure that develops around the closed blastopore.
id: XAO:0000082
has_related_synonym: circumblastoporal region

Axiom
annotated target: Embryonic structure that develops around the closed blastopore.
database_cross_reference: PMID:22138030
annotated property: definition
annotated source: circumblastoporal collar

involuted dorsal mesoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: circumblastoporal collar
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000039
definition: Dorsal mesoderm that has grown and curled inward during gastrulation.
id: XAO:0000083

Axiom
annotated target: Dorsal mesoderm that has grown and curled inward during gastrulation.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/involution
annotated property: definition
annotated source: involuted dorsal mesoderm

involuted ventral mesoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000039
subclass of: Restriction
  on property: part of
  some values from: circumblastoporal collar
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: Ventral mesoderm that has grown and curled inward during gastrulation.
id: XAO:0000084

Axiom
annotated target: Ventral mesoderm that has grown and curled inward during gastrulation.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/involution
annotated property: definition
annotated source: involuted ventral mesoderm

intermediate mesoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: part of
  some values from: mesoderm
database_cross_reference: AAO:0010575
definition: Mesoderm between somite and lateral plate. Traditionally thought to give rise to the urogenital system.
id: XAO:0000085
has_related_synonym: lateral plate mesoderm

Axiom
database_cross_reference: AAO:0010575
annotated target: Mesoderm between somite and lateral plate. Traditionally thought to give rise to the urogenital system.
annotated property: definition
annotated source: intermediate mesoderm

ciliary marginal zone
type: Class
subclass of: proliferative region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: retina
database_cross_reference: AAO:0010342
definition: The region at the periphery of the retina where retinal stem cells are located. It is spatially ordered with respect to cellular development and differentiation, with the youngest and least-determined stem cells closest to the periphery, the proliferative retinoblasts in the middle, and postmitotic cells at the central edge.
id: XAO:0000086

Axiom
database_cross_reference: PMID:15844194
annotated target: The region at the periphery of the retina where retinal stem cells are located. It is spatially ordered with respect to cellular development and differentiation, with the youngest and least-determined stem cells closest to the periphery, the proliferative retinoblasts in the middle, and postmitotic cells at the central edge.
annotated property: definition
annotated source: ciliary marginal zone

tail region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
definition: The anatomical region of the body posterior to the tail.
id: XAO:0000087
in_subset: anatomical site slim

Axiom
annotated target: The anatomical region of the body posterior to the tail.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: tail region

upper blastopore lip
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: blastopore lip
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000030
database_cross_reference: AAO:0010457
definition: Dorsal part of the blastopore lip, which forms as a result of the contraction of bottle cells.
id: XAO:0000088
has_related_synonym: dorsal blastopore lip

Axiom
annotated target: Dorsal part of the blastopore lip, which forms as a result of the contraction of bottle cells.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: upper blastopore lip

lower blastopore lip
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: blastopore lip
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000030
database_cross_reference: AAO:0010456
definition: Ventral part of the blastopore lip, which forms as a result of the contraction of bottle cells.
id: XAO:0000089
has_related_synonym: ventral blastopore lip

Axiom
annotated target: Ventral part of the blastopore lip, which forms as a result of the contraction of bottle cells.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: lower blastopore lip

endoderm
type: Class
subclass of: primary germ layer
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
database_cross_reference: AAO:0000139
definition: Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut.
id: XAO:0000090
has_related_synonym: entoderm
in_subset: frequent anatomy items

Axiom
database_cross_reference: OMD:endoderm
annotated target: Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut.
annotated property: definition
annotated source: endoderm

head endoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: endoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
definition: The endoderm of the head.
id: XAO:0000091

Axiom
annotated target: The endoderm of the head.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head endoderm

archenteron
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000019
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: part of
  some values from: endoderm
database_cross_reference: AAO:0010430
definition: The cavity of the gastrula forming a primitive gut. At NF stage 20-21 its wide canal becomes dorso-ventrally compressed and narrowed in the future trunk region so that a subdivision into a foregut, a midgut and a hindgut with protruding endodermal mass becomes manifest.
id: XAO:0000092
has_related_synonym: gastrocoel

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: NLM:archenteron
annotated target: The cavity of the gastrula forming a primitive gut. At NF stage 20-21 its wide canal becomes dorso-ventrally compressed and narrowed in the future trunk region so that a subdivision into a foregut, a midgut and a hindgut with protruding endodermal mass becomes manifest.
annotated property: definition
annotated source: archenteron

archenteron floor
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: archenteron
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000019
database_cross_reference: AAO:0010431
definition: The layer of cells forming the ventral surface of the archenteron space of the embryo.
id: XAO:0000093

Axiom
database_cross_reference: PMID:17540356
annotated target: The layer of cells forming the ventral surface of the archenteron space of the embryo.
annotated property: definition
annotated source: archenteron floor

archenteron roof
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
subclass of: Restriction
  on property: part of
  some values from: archenteron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000019
database_cross_reference: AAO:0010432
definition: The layer of cells forming the dorsal surface of the archenteron space of the embryo.
id: XAO:0000094
has_exact_synonym: gastrocoel roof

Axiom
database_cross_reference: PMID:17540356
annotated target: The layer of cells forming the dorsal surface of the archenteron space of the embryo.
annotated property: definition
annotated source: archenteron roof

lateral line system
type: Class
subclass of: sensory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
database_cross_reference: AAO:0000975
definition: Sensory system that has as it parts the sense organs that detect vibrations carried through water, develops during late tailbud stage, and persists in the adult bearing elaborate dorsal and ventral components. It develops from a specialized series of dorsolateral ectodermal placodes named lateral line placodes.
id: XAO:0000095
has_related_synonym: lateral line stitches
has_related_synonym: lateral-line organs

Axiom
database_cross_reference: AAO:0000975
database_cross_reference: ISBN:0471209627
database_cross_reference: ISBN:0815318960
annotated target: Sensory system that has as it parts the sense organs that detect vibrations carried through water, develops during late tailbud stage, and persists in the adult bearing elaborate dorsal and ventral components. It develops from a specialized series of dorsolateral ectodermal placodes named lateral line placodes.
annotated property: definition
annotated source: lateral line system

pharyngeal arch
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: part of
  some values from: pharyngeal region
subclass of: Restriction
  on property: part of
  some values from: head
definition: One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.
database_cross_reference: VSAO:0000149
id: XAO:0000096
has_related_synonym: pharyngeal arches
has_related_synonym: visceral arch
in_subset: frequent anatomy items

Axiom
database_cross_reference: NLM:branchial+arch
annotated target: One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.
annotated property: definition
annotated source: pharyngeal arch

Axiom
annotated target: pharyngeal arches
annotated source: pharyngeal arch
has_synonym_type: PLURAL
annotated property: has_related_synonym

mandibular arch
type: Class
subclass of: pharyngeal arch
subclass of: Restriction
  on property: part of
  some values from: splanchnocranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 1
database_cross_reference: AAO:0010364
definition: The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.
id: XAO:0000097
has_related_synonym: first visceral arch

Axiom
annotated target: The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: mandibular arch

hyoid arch
type: Class
subclass of: pharyngeal arch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 2
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010363
definition: The second of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.
id: XAO:0000098
has_related_synonym: second visceral arch

Axiom
annotated target: The second of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: hyoid arch

branchial arch
type: Class
subclass of: pharyngeal arch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010362
definition: The pharyngeal arches (which develop into the branchial arches) are anlage for a multitude of structures. Each pharyngeal arch has a cartilaginous stick, a muscle component which differentiates from the cartilaginous tissue, an artery, and a cranial nerve. Each of these is surrounded by mesenchyme. Arches do not develop simultaneously, but instead possess a \"staggered\" development.
id: XAO:0000099
has_related_synonym: branchial arches

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The pharyngeal arches (which develop into the branchial arches) are anlage for a multitude of structures. Each pharyngeal arch has a cartilaginous stick, a muscle component which differentiates from the cartilaginous tissue, an artery, and a cranial nerve. Each of these is surrounded by mesenchyme. Arches do not develop simultaneously, but instead possess a \"staggered\" development.
annotated property: definition
annotated source: branchial arch

Axiom
annotated target: branchial arches
annotated source: branchial arch
has_synonym_type: PLURAL
annotated property: has_related_synonym

cardiovascular system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011001
definition: Anatomical system that has as its parts the heart and blood vessels.
id: XAO:0000100

Axiom
annotated target: Anatomical system that has as its parts the heart and blood vessels.
database_cross_reference: BTO:0000088
annotated property: definition
annotated source: cardiovascular system

liver diverticulum
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000024
database_cross_reference: AAO:0011057
definition: An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Its anterior portion gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile duct.
id: XAO:0000101

Axiom
annotated target: An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Its anterior portion gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile duct.
database_cross_reference: UBERON:0008835
annotated property: definition
annotated source: liver diverticulum

visceral pouch 1
type: Class
subclass of: visceral pouch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
database_cross_reference: AAO:0011114
definition: First of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
id: XAO:0000102
has_exact_synonym: first visceral pouch

Axiom
annotated target: First of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
database_cross_reference: ISBN:0-226-55763-4
annotated property: definition
annotated source: visceral pouch 1

midgut
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: develops from
  some values from: archenteron
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
definition: Middle subdivision of the digestive tract. The midgut is the portion of the embryo from which most of the intestines develop. After it bends around the superior mesenteric artery, it is often referred to as the \"midgut loop\". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon.
database_cross_reference: UBERON:0001045
id: XAO:0000103

Axiom
annotated target: Middle subdivision of the digestive tract. The midgut is the portion of the embryo from which most of the intestines develop. After it bends around the superior mesenteric artery, it is often referred to as the \"midgut loop\". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon.
database_cross_reference: UBERON:0001045
database_cross_reference: XAO:curator
annotated property: definition
annotated source: midgut

hindgut
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: archenteron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: alimentary system
database_cross_reference: AAO:0011052
definition: Posterior subdivision of the digestive tract. The posterior part of the alimentary canal, including the large intestine and cloaca.
id: XAO:0000104

Axiom
annotated target: Posterior subdivision of the digestive tract. The posterior part of the alimentary canal, including the large intestine and cloaca.
database_cross_reference: UBERON:0001046
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hindgut

pharyngeal cavity
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010435
definition: The space enclosed by the walls of the pharynx.
id: XAO:0000105

Axiom
database_cross_reference: BTO:0002097
annotated target: The space enclosed by the walls of the pharynx.
annotated property: definition
annotated source: pharyngeal cavity

post-anal gut
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
subclass of: Restriction
  on property: part of
  some values from: archenteron
definition: A temporary extension of the embryonic gut caudal to the cloaca.
database_cross_reference: AAO:0010437
id: XAO:0000106

Axiom
annotated target: A temporary extension of the embryonic gut caudal to the cloaca.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/gut
annotated property: definition
annotated source: post-anal gut

tail bud
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: part of
  some values from: tail region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0011104
definition: Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25.
id: XAO:0000107
has_exact_synonym: tailbud
in_subset: frequent anatomy items

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: OMD:tail+bud
annotated target: Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25.
annotated property: definition
annotated source: tail bud

chordoneural hinge
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: tail bud
has_exact_synonym: CNH
definition: The anterior limit of the neurenteric canal, which connects the post-anal gut with the central canal of the spinal chord. It is formed from a population of cells derived from the dorsal lip of the late gastrula, and has been shown to be important in tail development.
database_cross_reference: UBERON:0007097
id: XAO:0000108
has_exact_synonym: chordo neural hinge

Axiom
database_cross_reference: ISBN:0-7623-0285-2
database_cross_reference: PMID:11404094
database_cross_reference: PMID:7916680
annotated target: The anterior limit of the neurenteric canal, which connects the post-anal gut with the central canal of the spinal chord. It is formed from a population of cells derived from the dorsal lip of the late gastrula, and has been shown to be important in tail development.
annotated property: definition
annotated source: chordoneural hinge

posterior wall of neurenteric canal
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: part of
  some values from: tail bud
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000043
definition: Structure formed by the ventral movement of the proctodeum anlage, which results in the shifting of the circumblastoral collar lateral walls to the posterior end of the embryo.
id: XAO:0000109
has_exact_synonym: posterior wall of NEC

Axiom
database_cross_reference: PMID:7916680
annotated target: Structure formed by the ventral movement of the proctodeum anlage, which results in the shifting of the circumblastoral collar lateral walls to the posterior end of the embryo.
annotated property: definition
annotated source: posterior wall of neurenteric canal

glomeral mesenchyme
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
definition: Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm.
id: XAO:0000110
has_related_synonym: corpuscle
has_related_synonym: glomerulus

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm.
annotated property: definition
annotated source: glomeral mesenchyme

germ cell
type: Class
subclass of: germ line cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
database_cross_reference: CL:0000586
definition: Cell type that is involved in the reproduction of the organism.
id: XAO:0000111
has_exact_synonym: germ cells
has_broad_synonym: germ line cell
has_broad_synonym: germ line cells

Axiom
annotated target: germ cells
annotated source: germ cell
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: Cell type that is involved in the reproduction of the organism.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: germ cell

Axiom
annotated target: germ line cells
annotated source: germ cell
has_synonym_type: PLURAL
annotated property: has_broad_synonym

embryo
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: develops from
  some values from: zygote
database_cross_reference: AAO:0011035
definition: Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems.
id: XAO:0000113
in_subset: frequent anatomy items

Axiom
annotated target: Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems.
database_cross_reference: BTO:0000379
annotated property: definition
annotated source: embryo

artery
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0010211
definition: Any of the tubular branching vessels that carry blood from the heart through the body.
id: XAO:0000114

Axiom
annotated target: Any of the tubular branching vessels that carry blood from the heart through the body.
database_cross_reference: NLM:artery
annotated property: definition
annotated source: artery

vein
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010212
definition: Any of the tubular branching vessels that carry blood from the capillaries toward the heart.
id: XAO:0000115

Axiom
annotated target: Any of the tubular branching vessels that carry blood from the capillaries toward the heart.
database_cross_reference: NLM:vein
annotated property: definition
annotated source: vein

capillary
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010252
definition: Any of the smallest blood vessels connecting arterioles with venules.
id: XAO:0000116

Axiom
annotated target: Any of the smallest blood vessels connecting arterioles with venules.
database_cross_reference: NLM:capillary
annotated property: definition
annotated source: capillary

respiratory system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0000541
definition: Anatomical system that has as its parts the organs involved in breathing in respiration (breathing).
id: XAO:0000117

Axiom
annotated target: Anatomical system that has as its parts the organs involved in breathing in respiration (breathing).
database_cross_reference: OMD:respiratory+apparatus
annotated property: definition
annotated source: respiratory system

trachea
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: respiratory system
database_cross_reference: AAO:0010140
definition: An elongated tube which carries air to and from the lungs.
id: XAO:0000118

Axiom
database_cross_reference: AAO:0010140
annotated target: An elongated tube which carries air to and from the lungs.
annotated property: definition
annotated source: trachea

lung
type: Class
subclass of: viscus
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000066
subclass of: Restriction
  on property: develops from
  some values from: lung primordium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: respiratory system
database_cross_reference: AAO:0010567
definition: Either of two organs which allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air.
id: XAO:0000119

Axiom
database_cross_reference: AAO:0010567
annotated target: Either of two organs which allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air.
annotated property: definition
annotated source: lung

external gill
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: develops from
  some values from: gill primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000065
subclass of: Restriction
  on property: part of
  some values from: respiratory system
database_cross_reference: AAO:0010174
definition: The primary respiration organ in some species of tadpoles, whose function is the extraction of oxygen from water and the excretion of carbon dioxide. The microscopic structure of a gill is such that it presents a very large surface area to the external environment. Gills usually consist of thin filaments of tissue, branches, or slender tufted processes which have a highly folded surface to increase surface area. A high surface area is crucial for effective gas exchange.
id: XAO:0000120
has_broad_synonym: gill

Axiom
annotated target: The primary respiration organ in some species of tadpoles, whose function is the extraction of oxygen from water and the excretion of carbon dioxide. The microscopic structure of a gill is such that it presents a very large surface area to the external environment. Gills usually consist of thin filaments of tissue, branches, or slender tufted processes which have a highly folded surface to increase surface area. A high surface area is crucial for effective gas exchange.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: external gill

bronchus
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000062
subclass of: Restriction
  on property: part of
  some values from: respiratory system
definition: A passage of airway in the respiratory tract that conducts air into the lungs.
database_cross_reference: AAO:0010524
id: XAO:0000121
has_exact_synonym: bronchial tube

Axiom
annotated target: A passage of airway in the respiratory tract that conducts air into the lungs.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: bronchus

hematological system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: death
has_exact_synonym: <new synonym>haematopoietic system
database_cross_reference: AAO:0011002
definition: Anatomical system that consists of the blood and blood forming tissues.
id: XAO:0000122
has_exact_synonym: haematological system
has_related_synonym: hematopoietic system

Axiom
annotated target: Anatomical system that consists of the blood and blood forming tissues.
database_cross_reference: OMD:haematological
annotated property: definition
annotated source: hematological system

bone marrow
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000010
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011007
definition: Flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells.
id: XAO:0000123

Axiom
annotated target: Flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells.
database_cross_reference: UBERON:0002371
annotated property: definition
annotated source: bone marrow

blood
type: Class
subclass of: portion of organism substance
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: anterior ventral blood island
database_cross_reference: AAO:0000046
definition: The fluid that circulates in the heart, arteries, capillaries, and veins carrying nourishment and oxygen to and bringing away waste products from all parts of the animal.
id: XAO:0000124

Axiom
database_cross_reference: NLM:blood
annotated target: The fluid that circulates in the heart, arteries, capillaries, and veins carrying nourishment and oxygen to and bringing away waste products from all parts of the animal.
annotated property: definition
annotated source: blood

alimentary system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes.
id: XAO:0000125
database_cross_reference: ZFA:0000339
has_related_synonym: digestive system
has_related_synonym: gut

Axiom
annotated target: Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes.
database_cross_reference: NLM:alimentary+system
annotated property: definition
annotated source: alimentary system

oral cavity
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: mouth
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: alimentary system
definition: The cavity of the mouth, bounded by the jaw bones and associated structures.
id: XAO:0000126
database_cross_reference: ZFA:0001027

Axiom
database_cross_reference: TAO:0001027
annotated target: The cavity of the mouth, bounded by the jaw bones and associated structures.
annotated property: definition
annotated source: oral cavity

esophagus
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
database_cross_reference: AAO:0000145
definition: Tube that connects the pharynx to the stomach. At NF stage 57 it is a straight tube, round in cross section, and starting from the pharynx runs backward along the dorsal side of the abdominal cavity. Its lining consists of a columnar glandular epithelium with mucus secreting cells. It is thrown into longitudinal folds.
id: XAO:0000127
has_exact_synonym: oesophagus

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: OMD:esophagus
annotated target: Tube that connects the pharynx to the stomach. At NF stage 57 it is a straight tube, round in cross section, and starting from the pharynx runs backward along the dorsal side of the abdominal cavity. Its lining consists of a columnar glandular epithelium with mucus secreting cells. It is thrown into longitudinal folds.
annotated property: definition
annotated source: esophagus

stomach
type: Class
subclass of: viscus
subclass of: cavitated compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: part of
  some values from: alimentary system
database_cross_reference: AAO:0000579
definition: Internal organ that is the dilated portion of the alimentary tract situated between the esophagus and the beginning of the duodenum. It produces gastric juices involved in the breakdown of food.
id: XAO:0000128

Axiom
annotated target: Internal organ that is the dilated portion of the alimentary tract situated between the esophagus and the beginning of the duodenum. It produces gastric juices involved in the breakdown of food.
database_cross_reference: OMD:stomach
annotated property: definition
annotated source: stomach

intestine
type: Class
subclass of: viscus
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
database_cross_reference: AAO:0000246
definition: Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.
id: XAO:0000129

Axiom
database_cross_reference: AAO:0000246
annotated target: Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.
annotated property: definition
annotated source: intestine

small intestine
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: intestine
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: develops from
  some values from: midgut
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A part of the alimentary system and principal organ of digestion, comprising the duodenum and ileum and characterized by longitudinal folds. In the tadpole it is a long simple tube with a single layer of cuboidal epithelial cells.
database_cross_reference: AAO:0010397
id: XAO:0000130

Axiom
annotated target: A part of the alimentary system and principal organ of digestion, comprising the duodenum and ileum and characterized by longitudinal folds. In the tadpole it is a long simple tube with a single layer of cuboidal epithelial cells.
database_cross_reference: PMID:15738398
annotated property: definition
annotated source: small intestine

large intestine
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: intestine
subclass of: Restriction
  on property: develops from
  some values from: hindgut
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A short, wide tube that is part of the alimentary system and comprises the colon and rectum and empties into the cloaca. It lacks longitudinal folds characteristic of the small intestine. It absorbs water and salts from the gut lumen.
database_cross_reference: AAO:0010396
id: XAO:0000131

Axiom
annotated target: A short, wide tube that is part of the alimentary system and comprises the colon and rectum and empties into the cloaca. It lacks longitudinal folds characteristic of the small intestine. It absorbs water and salts from the gut lumen.
database_cross_reference: PMID:21471667
annotated property: definition
annotated source: large intestine

liver and biliary system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011056
definition: Aantomical system comprising the liver, gall bladder, and associated ducts.
id: XAO:0000132

Axiom
annotated target: Aantomical system comprising the liver, gall bladder, and associated ducts.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: liver and biliary system

liver
type: Class
subclass of: viscus
subclass of: solid compound organ
subclass of: Restriction
  on property: develops from
  some values from: liver primordium
subclass of: Restriction
  on property: part of
  some values from: liver and biliary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010111
definition: Organ which secretes bile and participates in formation of certain blood proteins. The liver is the largest internal organ, primarily consisting of hepatocytes, and has a wider variety of functions than any other organs in the body. The hepatocyte is a polarized epithelial cell that exhibits both endocrine and exocrine properties. The biliary epithelial cells (cholangiocytes), sinusoidal endothelial cells, hepatic stellate cells (Ito cells), Kupffer cells, and pit cells (liver-specific natural killer cells) represent the majority of non- hepatocyte cell types in the liver. During embryogenesis, the liver is generated in the ventral foregut endoderm.
id: XAO:0000133

Axiom
database_cross_reference: AAO:0010111
annotated target: Organ which secretes bile and participates in formation of certain blood proteins. The liver is the largest internal organ, primarily consisting of hepatocytes, and has a wider variety of functions than any other organs in the body. The hepatocyte is a polarized epithelial cell that exhibits both endocrine and exocrine properties. The biliary epithelial cells (cholangiocytes), sinusoidal endothelial cells, hepatic stellate cells (Ito cells), Kupffer cells, and pit cells (liver-specific natural killer cells) represent the majority of non- hepatocyte cell types in the liver. During embryogenesis, the liver is generated in the ventral foregut endoderm.
database_cross_reference: PMID:17474120
annotated property: definition
annotated source: liver

bile duct
type: Class
subclass of: duct
subclass of: Restriction
  on property: part of
  some values from: liver and biliary system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: develops from
  some values from: liver diverticulum
database_cross_reference: AAO:0011019
definition: Duct that carries bile from the liver to the small intestine.
id: XAO:0000134
has_related_synonym: hepatic duct

Axiom
annotated target: Duct that carries bile from the liver to the small intestine.
database_cross_reference: ZFA:0001100
annotated property: definition
annotated source: bile duct

gall bladder
type: Class
subclass of: viscus
subclass of: compound organ
subclass of: Restriction
  on property: develops from
  some values from: liver diverticulum
subclass of: Restriction
  on property: part of
  some values from: liver and biliary system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: gall bladder primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
definition: A small organ of the alimentary system that aids mainly in fat digestion, and concentrates bile that is produced by the liver.
database_cross_reference: AAO:0010114
id: XAO:0000135
has_exact_synonym: gallbladder

Axiom
annotated target: A small organ of the alimentary system that aids mainly in fat digestion, and concentrates bile that is produced by the liver.
database_cross_reference: ZFA:0000208
annotated property: definition
annotated source: gall bladder

pancreas
type: Class
subclass of: viscus
subclass of: compound organ
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: develops from
  some values from: ventral pancreatic bud
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
database_cross_reference: AAO:0010112
definition: Internal gland organ with distinct tissues with different endocrine and exocrine functions. Its rudiment has three parts, one dorsal and two ventral primordia. The ventral can be first detected at NF stage 37/38. The dorsal is clearly segregated from the duodenal wall by NF stage 39. At NF stage 40 the right and left primordia have fused just above the gasto-duodenal vein. At NF stage 42 blood vessels penetrate into the crevices between the pancreatic acini making them more conspicuous.
id: XAO:0000136

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: ISBN:0881679860
annotated target: Internal gland organ with distinct tissues with different endocrine and exocrine functions. Its rudiment has three parts, one dorsal and two ventral primordia. The ventral can be first detected at NF stage 37/38. The dorsal is clearly segregated from the duodenal wall by NF stage 39. At NF stage 40 the right and left primordia have fused just above the gasto-duodenal vein. At NF stage 42 blood vessels penetrate into the crevices between the pancreatic acini making them more conspicuous.
annotated property: definition
annotated source: pancreas

exocrine pancreas
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
subclass of: Restriction
  on property: part of
  some values from: pancreas
database_cross_reference: AAO:0010407
definition: Pancreatic tissue composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.
id: XAO:0000137

Axiom
annotated target: Pancreatic tissue composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.
database_cross_reference: ZFA:0001249
annotated property: definition
annotated source: exocrine pancreas

mesentery
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: alimentary system
definition: A double layer composed of peritoneum that attaches the visceral organs to the body wall.
database_cross_reference: AAO:0011061
id: XAO:0000138

Axiom
annotated target: A double layer composed of peritoneum that attaches the visceral organs to the body wall.
database_cross_reference: ZFA:0005129
annotated property: definition
annotated source: mesentery

peritoneum
type: Class
subclass of: XAO_0004466
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: alimentary system
database_cross_reference: AAO:0010814
definition: Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.
id: XAO:0000139

Axiom
database_cross_reference: AAO:0010814
annotated target: Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.
annotated property: definition
annotated source: peritoneum

urogenital system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000624
definition: Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction.
id: XAO:0000140

Axiom
annotated target: Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction.
database_cross_reference: NLM:genitourinary+tract
annotated property: definition
annotated source: urogenital system

mesonephric kidney
type: Class
subclass of: kidney
subclass of: Restriction
  on property: part of
  some values from: trunk
subclass of: Restriction
  on property: develops from
  some values from: pronephric kidney
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
database_cross_reference: AAO:0010384
definition: Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.
id: XAO:0000141
has_related_synonym: adult kidney
has_related_synonym: mesonephros
has_related_synonym: opisthonephros

Axiom
database_cross_reference: AAO:0010384
annotated target: Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.
annotated property: definition
annotated source: mesonephric kidney

genital system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: develops from
  some values from: genital ridge
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011048
definition: Anatomical system that has as its parts the organs concerned with reproduction.
id: XAO:0000142
has_related_synonym: reproductive system

Axiom
annotated target: Anatomical system that has as its parts the organs concerned with reproduction.
database_cross_reference: NLM:genitourinary+tract
annotated property: definition
annotated source: genital system

urinary system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
database_cross_reference: AAO:0010257
definition: Anatomical system that has as its parts the organs concerned with the production and excretion of urine.
id: XAO:0000143

Axiom
annotated target: Anatomical system that has as its parts the organs concerned with the production and excretion of urine.
database_cross_reference: NLM:genitourinary+tract
annotated property: definition
annotated source: urinary system

ureter
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: urinary system
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010254
definition: Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.
id: XAO:0000144

Axiom
database_cross_reference: AAO:0010254
annotated target: Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.
annotated property: definition
annotated source: ureter

glomerulus
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: mesonephric nephron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
definition: A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated. Paired highly vascularized structures of the pronephros, responsible for blood filtration.
database_cross_reference: AAO:0010388
id: XAO:0000146
has_related_synonym: renal corpuscle

Axiom
annotated target: A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated. Paired highly vascularized structures of the pronephros, responsible for blood filtration.
database_cross_reference: AAO:0010388
database_cross_reference: XAO:curator
annotated property: definition
annotated source: glomerulus

glomerus
type: Class
comment: Made obolete - PV, perhaps a typo.
id: XAO:0000147
deprecated: true

mesonephric tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: mesonephric nephron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010389
definition: Any of the excretory units of the mesonephros, which connect to the mesonephric collecting duct.
id: XAO:0000148
has_related_synonym: renal tubule

Axiom
annotated target: Any of the excretory units of the mesonephros, which connect to the mesonephric collecting duct.
database_cross_reference: http://www.bionalogy.com/urinary_system.htm
annotated property: definition
annotated source: mesonephric tubule

renal proximal convoluted tubule
type: Class
id: XAO:0000149
consider: XAO:0000331
deprecated: true

loop of Henle
type: Class
id: XAO:0000150
deprecated: true

mesonephric collecting duct
type: Class
subclass of: duct
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: mesonephric tubule
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010390
definition: Duct which connects to the mesonephric nephrons and collects filtrate.
id: XAO:0000151
has_related_synonym: collecting duct

Axiom
annotated target: Duct which connects to the mesonephric nephrons and collects filtrate.
database_cross_reference: http://en.wikipedia.org/wiki/Collecting_duct_system
annotated property: definition
annotated source: mesonephric collecting duct

renal distal convoluted tubule
type: Class
id: XAO:0000152
consider: XAO:0000334
deprecated: true

urethra
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: urinary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: Anatomical structure consisting of a tube carries urine from the urinary bladder to the outside of the body.
id: XAO:0000153

Axiom
annotated target: Anatomical structure consisting of a tube carries urine from the urinary bladder to the outside of the body.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: urethra

bladder
type: Class
subclass of: viscus
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: urinary system
database_cross_reference: AAO:0000623
definition: The organ that collects urine excreted by the kidneys before disposal by urination.
id: XAO:0000154
has_exact_synonym: urinary bladder

Axiom
annotated target: The organ that collects urine excreted by the kidneys before disposal by urination.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: bladder

male genitalia
type: Class
subclass of: genital system
subclass of: Restriction
  on property: part of
  some values from: male organism
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: ends during
  some values from: death
definition: The organs of the male reproductive system.
id: XAO:0000155
has_related_synonym: male genitals

Axiom
annotated target: male genitals
annotated source: male genitalia
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
database_cross_reference: NLM:genitalia
annotated target: The organs of the male reproductive system.
annotated property: definition
annotated source: male genitalia

female genitalia
type: Class
subclass of: genital system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: part of
  some values from: female organism
definition: The organs of the female reproductive system.
id: XAO:0000156
has_related_synonym: female genitals

Axiom
database_cross_reference: NLM:genitalia
annotated target: The organs of the female reproductive system.
annotated property: definition
annotated source: female genitalia

Axiom
annotated target: female genitals
annotated source: female genitalia
has_synonym_type: PLURAL
annotated property: has_related_synonym

testis
type: Class
subclass of: gonad
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: male genitalia
database_cross_reference: AAO:0000606
definition: Reproductive organ that produces and releases sperm.
id: XAO:0000157
has_related_synonym: testes

Axiom
annotated target: testes
annotated source: testis
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Reproductive organ that produces and releases sperm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: testis

endocrine system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010279
definition: Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity.
id: XAO:0000158

Axiom
annotated target: Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity.
database_cross_reference: NLM:endocrine+system
annotated property: definition
annotated source: endocrine system

islets of Langerhans
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: develops from
  some values from: ventral pancreatic bud
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: endocrine system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: pancreas
definition: Structure that is made up of islet cells that produce insulin, glucagon, and somatostatin.
database_cross_reference: UBERON:0000016
id: XAO:0000159
has_related_synonym: endocrine pancreas

Axiom
annotated target: Structure that is made up of islet cells that produce insulin, glucagon, and somatostatin.
database_cross_reference: UBERON:0000016
annotated property: definition
annotated source: islets of Langerhans

pineal gland
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: endocrine system
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: midbrain
definition: An unpaired glandular organ subdivision attached on the midline near the posterior and habenular commissures of the epithalamus.
database_cross_reference: UBERON:0001905
id: XAO:0000160
has_related_synonym: epiphysis
has_related_synonym: pineal organ

Axiom
annotated target: An unpaired glandular organ subdivision attached on the midline near the posterior and habenular commissures of the epithalamus.
database_cross_reference: UBERON:0001905
annotated property: definition
annotated source: pineal gland

thyroid
type: Class
subclass of: compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000061
subclass of: Restriction
  on property: develops from
  some values from: thyroid primordium
subclass of: Restriction
  on property: part of
  some values from: endocrine system
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A two-lobed endocrine gland, located next to the trachea, and producing various hormones, such as triiodothyronine and calcitonin.
database_cross_reference: UBERON:0002046
id: XAO:0000162
has_exact_synonym: thyroid gland

Axiom
annotated target: A two-lobed endocrine gland, located next to the trachea, and producing various hormones, such as triiodothyronine and calcitonin.
database_cross_reference: UBERON:0002046
annotated property: definition
annotated source: thyroid

thymus
type: Class
subclass of: compound organ
subclass of: Restriction
  on property: part of
  some values from: endocrine system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: immune system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
definition: Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop.
id: XAO:0000163
database_cross_reference: ZFA:0001078

Axiom
annotated target: Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop.
database_cross_reference: NLM:thymus
annotated property: definition
annotated source: thymus

adrenal gland
type: Class
subclass of: solid compound organ
subclass of: Restriction
  on property: part of
  some values from: endocrine system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010551
definition: Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine.
id: XAO:0000164

Axiom
annotated target: Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine.
database_cross_reference: UBERON:0002369
annotated property: definition
annotated source: adrenal gland

adrenal cortex
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: part of
  some values from: adrenal gland
database_cross_reference: AAO:0011009
definition: Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis. The perimeter region of the adrenal gland, the site of steroid synthesis.
id: XAO:0000165
has_related_synonym: interrenal tissue

Axiom
database_cross_reference: PMID:14061885
annotated target: Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis. The perimeter region of the adrenal gland, the site of steroid synthesis.
database_cross_reference: UBERON:0001235
annotated property: definition
annotated source: adrenal cortex

adrenal medulla
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: trunk neural crest
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: part of
  some values from: adrenal gland
database_cross_reference: AAO:0011010
definition: Part of the adrenal gland, located at the center of the gland, being surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine, norepinephrine, and a small amount of dopamine in response to stimulation by sympathetic preganglionic neurons. Composed mainly of hormone-producing chromaffin cells, the adrenal medulla is the principal site of the conversion of the amino acid tyrosine into the catecholamines adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine.
id: XAO:0000166
has_related_synonym: chromaffin cells

Axiom
annotated target: Part of the adrenal gland, located at the center of the gland, being surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine, norepinephrine, and a small amount of dopamine in response to stimulation by sympathetic preganglionic neurons. Composed mainly of hormone-producing chromaffin cells, the adrenal medulla is the principal site of the conversion of the amino acid tyrosine into the catecholamines adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine.
database_cross_reference: UBERON:0001236
annotated property: definition
annotated source: adrenal medulla

parathyroid
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: develops from
  some values from: ultimobranchial body
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 2
subclass of: Restriction
  on property: develops from
  some values from: branchial arch 1
subclass of: Restriction
  on property: part of
  some values from: endocrine system
definition: An organ specialized for secretion of parathyroid hormone. It controls the amount of calcium in the blood and within the bones.
database_cross_reference: UBERON:0001132
id: XAO:0000167
has_alternative_id: XAO:0000450
has_related_synonym: epithelial body
has_exact_synonym: parathyroid gland

Axiom
annotated target: An organ specialized for secretion of parathyroid hormone. It controls the amount of calcium in the blood and within the bones.
database_cross_reference: UBERON:0001132
annotated property: definition
annotated source: parathyroid

musculoskeletal system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical system that provides locomotion and physical support to the organism.
database_cross_reference: VSAO:0000031
id: XAO:0000168

Axiom
annotated target: Anatomical system that provides locomotion and physical support to the organism.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: musculoskeletal system

bone tissue
type: Class
subclass of: skeletal tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: skeleton
definition: The hard form of connective tissue that constitutes the majority of the skeleton.
database_cross_reference: VSAO:0000047
id: XAO:0000169
has_related_synonym: bone

Axiom
database_cross_reference: BTO:0000140
annotated target: The hard form of connective tissue that constitutes the majority of the skeleton.
annotated property: definition
annotated source: bone tissue

cartilage tissue
type: Class
subclass of: skeletal tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: endoskeleton
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A type of dense connective tissue that is composed of specialized cells, chondrocytes, that produce a large amount of extracellular matrix.
database_cross_reference: VSAO:0000040
id: XAO:0000170
has_related_synonym: cartilage

Axiom
annotated target: A type of dense connective tissue that is composed of specialized cells, chondrocytes, that produce a large amount of extracellular matrix.
database_cross_reference: WIKI:Cartilage
annotated property: definition
annotated source: cartilage tissue

joint
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: XAO_0004274
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004313
definition: Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.
database_cross_reference: VSAO:0000101
id: XAO:0000171
has_exact_synonym: articulation

Axiom
annotated target: Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.
database_cross_reference: ZFA:0001596
annotated property: definition
annotated source: joint

muscle
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: muscular system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A body tissue consisting of long cells that contract when stimulated and produce motion.
database_cross_reference: AAO:0011066
id: XAO:0000172
in_subset: frequent anatomy items

Axiom
annotated target: A body tissue consisting of long cells that contract when stimulated and produce motion.
database_cross_reference: BTO:0000887
annotated property: definition
annotated source: muscle

tendon
type: Class
subclass of: dense regular connective tissue
subclass of: Restriction
  on property: develops from
  some values from: tendon fibroblast
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A fibrous, strong, connective tissue that connects muscle to bone.
database_cross_reference: VSAO:0000073
id: XAO:0000173
has_alternative_id: XAO:0000400

Axiom
annotated target: A fibrous, strong, connective tissue that connects muscle to bone.
database_cross_reference: OMD:tendon
annotated property: definition
annotated source: tendon

skeletal muscle
type: Class
subclass of: muscle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: myotome
definition: A type of muscle used to create movement, by applying force to bones and joints.
database_cross_reference: AAO:0011099
id: XAO:0000174

Axiom
annotated target: A type of muscle used to create movement, by applying force to bones and joints.
database_cross_reference: WIKI:Skeletal_muscle
annotated property: definition
annotated source: skeletal muscle

smooth muscle
type: Class
subclass of: muscle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
database_cross_reference: AAO:0010244
definition: Involuntary muscle tissue consisting of uninucleate spindle-shaped fibers.
id: XAO:0000175
has_related_synonym: visceral muscle

Axiom
database_cross_reference: AAO:0010244
annotated target: Involuntary muscle tissue consisting of uninucleate spindle-shaped fibers.
annotated property: definition
annotated source: smooth muscle

dermal system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical system that consists of the skin and its appendages.
database_cross_reference: VSAO:00000130
id: XAO:0000176

Axiom
annotated target: Anatomical system that consists of the skin and its appendages.
database_cross_reference: OMD:dermal+system
annotated property: definition
annotated source: dermal system

nervous system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000324
definition: Anatomical system that has as its parts the brain and spinal cord, nerves, ganglia, and parts of the receptor organs and that receives and interprets stimuli and transmits impulses to the effector organs.
id: XAO:0000177
in_subset: frequent anatomy items

Axiom
database_cross_reference: AAO:0000324
annotated target: Anatomical system that has as its parts the brain and spinal cord, nerves, ganglia, and parts of the receptor organs and that receives and interprets stimuli and transmits impulses to the effector organs.
annotated property: definition
annotated source: nervous system

peripheral nervous system
type: Class
subclass of: nervous system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000429
definition: One of the two major divisions of the nervous system. Its nerves connect the central nervous system with sensory organs, other organs, muscles, blood vessels and glands.
has_exact_synonym: PNS
id: XAO:0000178

Axiom
database_cross_reference: OMD:peripheral+nervous+system
annotated target: One of the two major divisions of the nervous system. Its nerves connect the central nervous system with sensory organs, other organs, muscles, blood vessels and glands.
annotated property: definition
annotated source: peripheral nervous system

eye
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: central nervous system
subclass of: Restriction
  on property: develops from
  some values from: optic vesicle
database_cross_reference: AAO:0010340
definition: The organ of sight (visual apparatus), almost spherical in shape. At the end of development (NF stage 66) the eyes bulge out of their orbital capsules near the lateral edge of the dorsal side of the head.
id: XAO:0000179
has_related_synonym: eyes
in_subset: frequent anatomy items

Axiom
database_cross_reference: ISBN:0815318960
annotated target: The organ of sight (visual apparatus), almost spherical in shape. At the end of development (NF stage 66) the eyes bulge out of their orbital capsules near the lateral edge of the dorsal side of the head.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: eye

Axiom
annotated target: eyes
annotated source: eye
has_synonym_type: PLURAL
annotated property: has_related_synonym

cornea
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0010344
definition: The transparent front part of the eye that, together with the lens, refracts light.
id: XAO:0000180

Axiom
annotated target: The transparent front part of the eye that, together with the lens, refracts light.
database_cross_reference: WIKI:Cornea
annotated property: definition
annotated source: cornea

globe
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: A general term for the whole eye, or eye ball, of an organism.
database_cross_reference: AAO:0010346
id: XAO:0000181
has_exact_synonym: eye ball

Axiom
annotated target: A general term for the whole eye, or eye ball, of an organism.
database_cross_reference: AAO:0010346
annotated property: definition
annotated source: globe

conjunctiva
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000056
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: eye
definition: A clear mucous membrane consisting of cells and underlying basement membrane that covers the sclera and lines the inside of the eyelids. It is made of epithelial tissue.
database_cross_reference: AAO:0010343
id: XAO:0000182
has_exact_synonym: conjunctivae
has_exact_synonym: conjunctivas

Axiom
annotated target: conjunctivae
annotated source: conjunctiva
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: A clear mucous membrane consisting of cells and underlying basement membrane that covers the sclera and lines the inside of the eyelids. It is made of epithelial tissue.
database_cross_reference: UBERON:0001811
annotated property: definition
annotated source: conjunctiva

Axiom
annotated target: conjunctivas
annotated source: conjunctiva
has_synonym_type: PLURAL
annotated property: has_exact_synonym

sclera
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010354
definition: The opaque, fibrous, protective, outer layer of the eye containing collagen and elastic fiber.
id: XAO:0000183

Axiom
annotated target: The opaque, fibrous, protective, outer layer of the eye containing collagen and elastic fiber.
database_cross_reference: UBERON:0001773
annotated property: definition
annotated source: sclera

iris
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: develops from
  some values from: optic vesicle
definition: A membrane in the eye, responsible for controlling the amount of light reaching the retina.
database_cross_reference: AAO:0010347
id: XAO:0000185

Axiom
annotated target: A membrane in the eye, responsible for controlling the amount of light reaching the retina.
database_cross_reference: UBERON:0001769
annotated property: definition
annotated source: iris

ciliary body
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000056
database_cross_reference: AAO:0010341
definition: Circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.
id: XAO:0000186

Axiom
annotated target: Circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.
database_cross_reference: UBERON:0001775
annotated property: definition
annotated source: ciliary body

dorsolateral placode region
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
definition: Lateral neurogenic placode region positioned dorsal to the epibranchial placodes, and include the lateral line placodes, the otic placode and the trigeminal placode.
id: XAO:0000187
database_cross_reference: ZFA:0001310

Axiom
database_cross_reference: ISBN:0878933840
annotated target: Lateral neurogenic placode region positioned dorsal to the epibranchial placodes, and include the lateral line placodes, the otic placode and the trigeminal placode.
database_cross_reference: ZFA:0001310
annotated property: definition
annotated source: dorsolateral placode region

cranial nerve II
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Cranial nerve that runs to the eye.
id: XAO:0000188
database_cross_reference: ZFA:0000435
has_related_synonym: optic nerve

Axiom
annotated target: Cranial nerve that runs to the eye.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve II

auditory apparatus
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: otic vesicle
subclass of: Restriction
  on property: part of
  some values from: vestibuloauditory system
database_cross_reference: AAO:0011014
definition: The combination of structures that form the ear and function to transmit vibrations and permit hearing.
id: XAO:0000189
has_broad_synonym: ear

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The combination of structures that form the ear and function to transmit vibrations and permit hearing.
annotated property: definition
annotated source: auditory apparatus

external ear
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: auditory apparatus
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
database_cross_reference: AAO:0011108
definition: The thin membrane or integument, which is stretched over a cartilaginous annulus in a drum-like manner, and forms the outer ear, receiving airborne vibrations and functions in hearing.
id: XAO:0000190
has_alternative_id: XAO:0000212
has_related_synonym: tympanic membrane
has_related_synonym: tympanum

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The thin membrane or integument, which is stretched over a cartilaginous annulus in a drum-like manner, and forms the outer ear, receiving airborne vibrations and functions in hearing.
annotated property: definition
annotated source: external ear

middle ear
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: auditory apparatus
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
database_cross_reference: AAO:0011065
definition: The air-filled cavity within the skull that lies between the outer ear and the inner ear.
id: XAO:0000191
has_exact_synonym: tympanic cavity

Axiom
annotated target: The air-filled cavity within the skull that lies between the outer ear and the inner ear.
database_cross_reference: UBERON:0001756
annotated property: definition
annotated source: middle ear

inner ear
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: auditory apparatus
database_cross_reference: AAO:0000238
definition: Labyrinthine anatomical cluster that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation.
id: XAO:0000192
has_alternative_id: XAO:0000194
has_exact_synonym: membranous labyrinth

Axiom
annotated target: Labyrinthine anatomical cluster that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation.
database_cross_reference: PMID:16217737
annotated property: definition
annotated source: inner ear

osseous labyrinth
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011078
definition: Structure consisting of the vestibule, lagena, and semicircular canal, cavities that are hollowed out of the substance of the bone, and lined by periosteum. They contain a clear fluid, the perilymph, in which the membranous labyrinth is situated.
id: XAO:0000193
has_related_synonym: bony labyrinth

Axiom
annotated target: Structure consisting of the vestibule, lagena, and semicircular canal, cavities that are hollowed out of the substance of the bone, and lined by periosteum. They contain a clear fluid, the perilymph, in which the membranous labyrinth is situated.
database_cross_reference: http://en.wikipedia.org/wiki/Bony_labyrinth
annotated property: definition
annotated source: osseous labyrinth

utricle
type: Class
subclass of: auditory ossicle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011109
definition: Inner ear structure into which the semicircular ducts find their outlet. Along with the saccule, it is part of the balancing apparatus (membranous labyrinth) located within the vestibule of the osseous labyrinth.
id: XAO:0000195

Axiom
annotated target: Inner ear structure into which the semicircular ducts find their outlet. Along with the saccule, it is part of the balancing apparatus (membranous labyrinth) located within the vestibule of the osseous labyrinth.
database_cross_reference: http://en.wikipedia.org/wiki/Utricle_(ear)
annotated property: definition
annotated source: utricle

sacculus
type: Class
subclass of: auditory ossicle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A major structure of the inner ear, ventral to the utriculus. Two small pouches extend from it: the papilla basilaris, and the papilla amphibiorum. The sacculus functions in the detection of sound.
database_cross_reference: AAO:0000550
id: XAO:0000196
has_related_synonym: saccule

Axiom
annotated target: A major structure of the inner ear, ventral to the utriculus. Two small pouches extend from it: the papilla basilaris, and the papilla amphibiorum. The sacculus functions in the detection of sound.
database_cross_reference: ISBN:0-07-017977-8
annotated property: definition
annotated source: sacculus

lagena
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: osseous labyrinth
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A vestibular structure of the inner ear consisting of a ventral diverticulum off of the sacculus.
database_cross_reference: AAO:0000253
id: XAO:0000197
has_related_synonym: cochlea

Axiom
annotated target: A vestibular structure of the inner ear consisting of a ventral diverticulum off of the sacculus.
database_cross_reference: ISBN:1402073755
annotated property: definition
annotated source: lagena

semicircular canal
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: osseous labyrinth
database_cross_reference: AAO:0011098
definition: Fluid-filled ducts that loop from the utriculus in the inner ear, and help detect movement and maintain balance.
id: XAO:0000198
has_related_synonym: semicircular canals
has_related_synonym: semicircular ducts

Axiom
annotated target: semicircular canals
annotated source: semicircular canal
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Fluid-filled ducts that loop from the utriculus in the inner ear, and help detect movement and maintain balance.
database_cross_reference: ISBN:0-07-017977-8
annotated property: definition
annotated source: semicircular canal

Axiom
annotated target: semicircular ducts
annotated source: semicircular canal
has_synonym_type: PLURAL
annotated property: has_related_synonym

vestibule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: osseous labyrinth
definition: The small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear.
database_cross_reference: UBERON:0005236
id: XAO:0000199

Axiom
annotated target: The small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear.
database_cross_reference: UBERON:0005236
annotated property: definition
annotated source: vestibule

animal blastomere
type: Class
subclass of: blastomere
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000011
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000019
subclass of: Restriction
  on property: develops from
  some values from: animal hemisphere
database_cross_reference: AAO:0010283
definition: Pigmented, smaller blastomere of the animal (upper) hemisphere of the cleaving embryo.
id: XAO:0000200
has_related_synonym: micromere

Axiom
database_cross_reference: ISBN:0471209627
annotated target: Pigmented, smaller blastomere of the animal (upper) hemisphere of the cleaving embryo.
annotated property: definition
annotated source: animal blastomere

olfactory apparatus
type: Class
id: XAO:0000201
consider: XAO:0000273
deprecated: true

animal hemisphere
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: part of
  some values from: zygote
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000021
database_cross_reference: AAO:0010325
definition: In developmental biology, the embryo is divided into two hemispheres: the animal pole or hemisphere and the vegetal pole or hemisphere. The animal hemisphere is the actively dividing hemisphere of the embryo, opposite the vegetal hemisphere, and is pigmented dark brown.
id: XAO:0000202

Axiom
database_cross_reference: ISBN:3-921015-04-9
annotated target: In developmental biology, the embryo is divided into two hemispheres: the animal pole or hemisphere and the vegetal pole or hemisphere. The animal hemisphere is the actively dividing hemisphere of the embryo, opposite the vegetal hemisphere, and is pigmented dark brown.
annotated property: definition
annotated source: animal hemisphere

archencephalic region
type: Class
id: XAO:0000203
deprecated: true

peripheral nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors.
id: XAO:0000204

Axiom
annotated target: Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors.
database_cross_reference: NCIt:Peripheral_Nerve
annotated property: definition
annotated source: peripheral nerve

axial mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: XAO_0004406
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000049
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
definition: A type of mesoderm that lies along the central axis, under the neural tube, and gives rise to the notochord.
database_cross_reference: AAO:0011017
id: XAO:0000205
has_related_synonym: chordamesoderm

Axiom
annotated target: A type of mesoderm that lies along the central axis, under the neural tube, and gives rise to the notochord.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: axial mesoderm

blastocoel anlage
type: Class
subclass of: primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000018
database_cross_reference: AAO:0010326
definition: The first appearance of the anatomical space that will become the blastocoel.
id: XAO:0000206

Axiom
annotated target: The first appearance of the anatomical space that will become the blastocoel.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: blastocoel anlage

blastocoel roof
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: part of
  some values from: blastocoel
database_cross_reference: AAO:0010436
definition: The dorsal surface of the blastocoel, the cavity of the blastula.
id: XAO:0000207

Axiom
annotated target: The dorsal surface of the blastocoel, the cavity of the blastula.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: blastocoel roof

blastopore
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000034
database_cross_reference: AAO:0000045
definition: The opening of the archenteron to the exterior, marks the point of orgin of the archenteron and the caudal end of the embryo.
id: XAO:0000208

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The opening of the archenteron to the exterior, marks the point of orgin of the archenteron and the caudal end of the embryo.
annotated property: definition
annotated source: blastopore

ganglion
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
database_cross_reference: AAO:0010426
definition: Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.
id: XAO:0000209
has_related_synonym: ganglia

Axiom
database_cross_reference: NLM:ganglion
annotated target: Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.
annotated property: definition
annotated source: ganglion

Axiom
annotated target: ganglia
annotated source: ganglion
has_synonym_type: PLURAL
annotated property: has_related_synonym

spinal ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
definition: A nodule on a dorsal root that contains cell bodies of neurons in afferent spinal nerves.
id: XAO:0000210

Axiom
annotated target: A nodule on a dorsal root that contains cell bodies of neurons in afferent spinal nerves.
database_cross_reference: http://en.wikipedia.org/wiki/Dorsal_root_ganglion
annotated property: definition
annotated source: spinal ganglion

sympathetic chain
type: Class
subclass of: nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
database_cross_reference: AAO:0010791
definition: Either of the pair of ganglionated longitudinal cords of the sympathetic nervous system of which one is situated on each side of the spinal column.
id: XAO:0000211
has_exact_synonym: sympathetic trunk

Axiom
annotated target: Either of the pair of ganglionated longitudinal cords of the sympathetic nervous system of which one is situated on each side of the spinal column.
database_cross_reference: http://www.merriam-webster.com/medical/sympathetic%20chain
annotated property: definition
annotated source: sympathetic chain

auditory tube
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: auditory apparatus
database_cross_reference: AAO:0011016
definition: The narrow tube connecting the middle ear with the pharynx, through which air flows to equalize pressure on either side of the tympanic membrane.
id: XAO:0000213
has_exact_synonym: eustachian tube
has_exact_synonym: pharyngotympanic tube

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The narrow tube connecting the middle ear with the pharynx, through which air flows to equalize pressure on either side of the tympanic membrane.
annotated property: definition
annotated source: auditory tube

auditory ossicle
type: Class
subclass of: XAO_0004276
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: part of
  some values from: auditory apparatus
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011015
definition: Any of the three tiny bones of the inner ear (columella or stapes, the sacculus and the utriculus) suspended in the otic capsule.
id: XAO:0000214

Axiom
annotated target: Any of the three tiny bones of the inner ear (columella or stapes, the sacculus and the utriculus) suspended in the otic capsule.
database_cross_reference: ISBN:0-07-017977-8
annotated property: definition
annotated source: auditory ossicle

central nervous system
type: Class
subclass of: nervous system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000090
has_exact_synonym: CNS
definition: The part of the nervous system that consists of the brain and spinal cord, to which sensory impulses are transmitted and from which motor impulses pass out, and that supervises and coordinates the activity of the entire nervous system.
id: XAO:0000215

Axiom
database_cross_reference: NLM:central+nervous+system
annotated target: The part of the nervous system that consists of the brain and spinal cord, to which sensory impulses are transmitted and from which motor impulses pass out, and that supervises and coordinates the activity of the entire nervous system.
annotated property: definition
annotated source: central nervous system

cortex
type: Class
definition: Spatial descriptor for the outermost or superficial layer of an organ, such at the cerebral cortex or adrenal gland cortex; or the outer most layers of the oocyte.
id: XAO:0000216
consider: XAO:0004467
consider: XAO:0004468
deprecated: true

Axiom
annotated target: Spatial descriptor for the outermost or superficial layer of an organ, such at the cerebral cortex or adrenal gland cortex; or the outer most layers of the oocyte.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cortex

dermis
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: skin
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: dermatome
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis.
database_cross_reference: AAO:0000128
id: XAO:0000217

Axiom
annotated target: A layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis.
database_cross_reference: UBERON:0002067
annotated property: definition
annotated source: dermis

appendage
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000066
subclass of: Restriction
  on property: ends during
  some values from: death
definition: An internal or external body part or prolongation that projects from, and is attached to, an organ or the main body of an organism.
database_cross_reference: VSAO:0000075
id: XAO:0000218
has_related_synonym: appendages

Axiom
annotated target: appendages
annotated source: appendage
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: An internal or external body part or prolongation that projects from, and is attached to, an organ or the main body of an organism.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: appendage

superficial (epithelial) layer
type: Class
id: XAO:0000219
deprecated: true

dermatome
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 3
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 12
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 15
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 17
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 9
subclass of: Restriction
  on property: develops from
  some values from: head somite 4
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 2
subclass of: Restriction
  on property: develops from
  some values from: head somite 2
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 8
subclass of: Restriction
  on property: develops from
  some values from: head somite 1
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 13
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 16
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 10
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 11
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 7
subclass of: Restriction
  on property: develops from
  some values from: head somite 3
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 14
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 1
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: somite
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 5
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 4
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 6
database_cross_reference: AAO:0011028
definition: Somitic compartment that is a precursor of dermis, the cells of which become arranged in a single layer that blankets the myotome, possibly continuously (unsegmented) across somites.
id: XAO:0000220

Axiom
database_cross_reference: PMID:17313522
annotated target: Somitic compartment that is a precursor of dermis, the cells of which become arranged in a single layer that blankets the myotome, possibly continuously (unsegmented) across somites.
annotated property: definition
annotated source: dermatome

deuterencephalic region
type: Class
id: XAO:0000221
deprecated: true

ear placode
type: Class
id: XAO:0000222
term replaced by: XAO:0000223
deprecated: true

otic placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: part of
  some values from: vestibuloauditory system
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000042
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
database_cross_reference: AAO:0011079
definition: Invagination of thickened epithelium near the hindbrain that gives rise to a spherically shaped ear vesicle.
id: XAO:0000223
has_related_synonym: auditory placode
has_broad_synonym: ear

Axiom
annotated target: Invagination of thickened epithelium near the hindbrain that gives rise to a spherically shaped ear vesicle.
database_cross_reference: PMID:16217737
annotated property: definition
annotated source: otic placode

vegetal part, early involuting
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: involuting marginal zone
definition: Vegetal portion of the marginal zone of the embryo that turns inside the embryo during involution.
id: XAO:0000224

Axiom
annotated target: Vegetal portion of the marginal zone of the embryo that turns inside the embryo during involution.
database_cross_reference: http://worms.zoology.wisc.edu/frogs/glossary.html
annotated property: definition
annotated source: vegetal part, early involuting

trigeminal placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: develops from
  some values from: dorsolateral placode region
definition: The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.
id: XAO:0000225
database_cross_reference: ZFA:0000162

Axiom
database_cross_reference: PMID:21452441
annotated target: The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.
database_cross_reference: UBERON:0003070
annotated property: definition
annotated source: trigeminal placode

equatorial belt
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000001
subclass of: Restriction
  on property: part of
  some values from: zygote
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: AAO:0010328
definition: Equatorial zone of the zygote with which the plane of first cleavage aligns.
id: XAO:0000226

Axiom
annotated target: Equatorial zone of the zygote with which the plane of first cleavage aligns.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: equatorial belt

eye primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000027
subclass of: Restriction
  on property: develops from
  some values from: optic field
database_cross_reference: AAO:0011038
definition: First trace of the future visual apparatus. The eye primordia forming antero-lateral evaginations of the closing neural tube are originally massive formations into which only a slit-shaped extension of the neural groove penetrates at NF stage 18. At NF stage 19 they clearly segregate from the anterior portion of the neural tube.
id: XAO:0000227
has_broad_synonym: eye
has_related_synonym: eye anlage

Axiom
annotated target: First trace of the future visual apparatus. The eye primordia forming antero-lateral evaginations of the closing neural tube are originally massive formations into which only a slit-shaped extension of the neural groove penetrates at NF stage 18. At NF stage 19 they clearly segregate from the anterior portion of the neural tube.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: eye primordium

optic vesicle
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000047
subclass of: Restriction
  on property: develops from
  some values from: forebrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: develops from
  some values from: eye primordium
subclass of: Restriction
  on property: part of
  some values from: visual system
database_cross_reference: AAO:0011039
definition: The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. Portion of tissue that is composed of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup.
id: XAO:0000228
has_broad_synonym: eye
has_related_synonym: eye vesicle
has_related_synonym: optic cup

Axiom
annotated target: The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. Portion of tissue that is composed of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: optic vesicle

fasciculated network of fibrils
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000083
subclass of: Restriction
  on property: part of
  some values from: oocyte
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000092
database_cross_reference: AAO:0010303
definition: Randomly dispersed fibrils organized into criss-crossing fascicles or bundles in the coelomic envelope of oocytes.
id: XAO:0000229
has_broad_synonym: coelomic envelope

Axiom
database_cross_reference: PMID:2909400
annotated target: Randomly dispersed fibrils organized into criss-crossing fascicles or bundles in the coelomic envelope of oocytes.
annotated property: definition
annotated source: fasciculated network of fibrils

follicle cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000066
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: ovary
database_cross_reference: CL:0000477
definition: Cell type that forms a layer within an ovarian follicle that surrounds the oocyte.
id: XAO:0000230

Axiom
annotated target: Cell type that forms a layer within an ovarian follicle that surrounds the oocyte.
database_cross_reference: OMD:follicle+cell
annotated property: definition
annotated source: follicle cell

follicle layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000066
subclass of: Restriction
  on property: part of
  some values from: ovary
definition: A monolayer of follicle cells surrounding the developing oocyte and forming adhesive contacts with the surrounding follicular epithelium.
database_cross_reference: AAO:0010398
id: XAO:0000231

Axiom
annotated target: A monolayer of follicle cells surrounding the developing oocyte and forming adhesive contacts with the surrounding follicular epithelium.
database_cross_reference: PMID:619165
annotated property: definition
annotated source: follicle layer

foregut
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: develops from
  some values from: archenteron
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: alimentary system
database_cross_reference: AAO:0011042
definition: The anterior part of the alimentary system, from the mouth and esophagus to the duodenum at the entrance of the bile duct. Structures of the foregut are: esophagus, stomach, duodenum, liver, gall bladder, and pancreas. The spleen is located in the foregut region, but is not a gut organ.
id: XAO:0000232

Axiom
annotated target: The anterior part of the alimentary system, from the mouth and esophagus to the duodenum at the entrance of the bile duct. Structures of the foregut are: esophagus, stomach, duodenum, liver, gall bladder, and pancreas. The spleen is located in the foregut region, but is not a gut organ.
database_cross_reference: UBERON:0001041
database_cross_reference: XAO:curator
annotated property: definition
annotated source: foregut

germ plasm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: vegetal hemisphere
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
definition: A zone found in the cytoplasm of the egg cells which contains determinants that will give rise to the germ cell lineage. As the zygote undergoes mitotic divisions the germ plasm is ultimately restricted to a few cells of the embryo. These germ cells then migrate to the gonads.
database_cross_reference: AAO:0010333
id: XAO:0000233

Axiom
annotated target: A zone found in the cytoplasm of the egg cells which contains determinants that will give rise to the germ cell lineage. As the zygote undergoes mitotic divisions the germ plasm is ultimately restricted to a few cells of the embryo. These germ cells then migrate to the gonads.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: germ plasm

germinal vesicle
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: oocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000088
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000092
database_cross_reference: AAO:0010305
has_exact_synonym: GV
definition: The nucelus of the oocyte, it is enclosed in a nuclear envelope and contains neucleoplasm, in which the chromosomes and extranucleoli are embedded. It breaks down as the oocyte matures, being no longer visible by the first meiotic metaphase.
id: XAO:0000234

Axiom
annotated target: The nucelus of the oocyte, it is enclosed in a nuclear envelope and contains neucleoplasm, in which the chromosomes and extranucleoli are embedded. It breaks down as the oocyte matures, being no longer visible by the first meiotic metaphase.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: germinal vesicle

cardiac mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000037
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
database_cross_reference: AAO:0011021
definition: Two migratory heart primordia that move ventrally during the course of neurulation, and whose fusion begins at the ventral midline at NF stage 16.
id: XAO:0000235
has_broad_synonym: heart

Axiom
annotated target: Two migratory heart primordia that move ventrally during the course of neurulation, and whose fusion begins at the ventral midline at NF stage 16.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cardiac mesoderm

duodenum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: small intestine
database_cross_reference: AAO:0010402
definition: The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one).
id: XAO:0000236

Axiom
database_cross_reference: ISBN:0815318960
annotated target: The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one).
annotated property: definition
annotated source: duodenum

ileum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: small intestine
database_cross_reference: AAO:0010403
definition: The final section of the small intestine.
id: XAO:0000237

Axiom
annotated target: The final section of the small intestine.
database_cross_reference: UBERON:0002116
annotated property: definition
annotated source: ileum

rectum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: large intestine
database_cross_reference: AAO:0010401
definition: The terminal portion of the large intestine.
id: XAO:0000238

Axiom
annotated target: The terminal portion of the large intestine.
database_cross_reference: VHOG:0001751
annotated property: definition
annotated source: rectum

hepato-pancreatic duct
type: Class
subclass of: duct
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: liver diverticulum
subclass of: Restriction
  on property: part of
  some values from: liver and biliary system
subclass of: Restriction
  on property: ends during
  some values from: death
definition: The pancreatic duct and common bile duct enter the descending duodenum, commonly known together as the hepatopancreatic duct.
id: XAO:0000239

Axiom
annotated target: The pancreatic duct and common bile duct enter the descending duodenum, commonly known together as the hepatopancreatic duct.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hepato-pancreatic duct

lens placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
definition: A thickened portion of ectoderm which serves as the precursor to the lens. It invaginates to form the lens vesicle, which gives rise to the crystallin-accumulating cells of the lens.
database_cross_reference: AAO:0011055
id: XAO:0000240
has_broad_synonym: lens

Axiom
annotated target: A thickened portion of ectoderm which serves as the precursor to the lens. It invaginates to form the lens vesicle, which gives rise to the crystallin-accumulating cells of the lens.
database_cross_reference: PMID:16677629
database_cross_reference: UBERON:0003073
annotated property: definition
annotated source: lens placode

posterior cardinal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: cardinal vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
database_cross_reference: AAO:0011081
has_exact_synonym: PCV
definition: The posterior cardinal vein returns blood from the trunk and drains into the duct of Cuvier via the pronephric sinus.
id: XAO:0000241

Axiom
database_cross_reference: PMID:12606281
annotated target: The posterior cardinal vein returns blood from the trunk and drains into the duct of Cuvier via the pronephric sinus.
annotated property: definition
annotated source: posterior cardinal vein

mesonephric duct
type: Class
subclass of: duct
subclass of: Restriction
  on property: develops from
  some values from: pronephric duct
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Duct which drains the mesonephros and connects it to the ureter.
has_related_synonym: Wolffian duct
id: XAO:0000242
database_cross_reference: ZFA:0000546

Axiom
annotated target: Duct which drains the mesonephros and connects it to the ureter.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: mesonephric duct

colon
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: large intestine
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
database_cross_reference: AAO:0010400
definition: The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body.
id: XAO:0000243
has_broad_synonym: hindgut
has_related_synonym: posterior intestine

Axiom
annotated target: The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body.
database_cross_reference: UBERON:0001155
annotated property: definition
annotated source: colon

cloaca
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: part of
  some values from: tail bud
database_cross_reference: AAO:0000095
definition: The posterior opening that serves as the only such opening for the intestinal, reproductive, and urinary tracts.
id: XAO:0000244
has_related_synonym: cloacal chamber
has_related_synonym: vent
in_subset: frequent anatomy items

Axiom
annotated target: The posterior opening that serves as the only such opening for the intestinal, reproductive, and urinary tracts.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cloaca

mitochondrial aggregate
type: Class
subclass of: XAO_0004290
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000083
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000083
subclass of: Restriction
  on property: part of
  some values from: oocyte
definition: A prominent mass in the cytoplasm of previtellogenic oocytes, containing both mitochondria and electron-dense granulofibrillar material.
database_cross_reference: AAO:0010306
id: XAO:0000245

Axiom
annotated target: A prominent mass in the cytoplasm of previtellogenic oocytes, containing both mitochondria and electron-dense granulofibrillar material.
database_cross_reference: PMID:6541166
annotated property: definition
annotated source: mitochondrial aggregate

myocoelic slit
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: part of
  some values from: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000034
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000026
definition: Space that separates the thicker inner sheet of splanchnic mesoderm from the thinner outer somatic mesoderm.
id: XAO:0000246

Axiom
database_cross_reference: PMID:5449482
annotated target: Space that separates the thicker inner sheet of splanchnic mesoderm from the thinner outer somatic mesoderm.
annotated property: definition
annotated source: myocoelic slit

visceral pouch 2
type: Class
subclass of: visceral pouch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
database_cross_reference: AAO:0011115
definition: Second of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
id: XAO:0000247
has_exact_synonym: second visceral pouch

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: Second of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
annotated property: definition
annotated source: visceral pouch 2

neural groove
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: neural plate
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
database_cross_reference: AAO:0011071
definition: The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds.
id: XAO:0000248

Axiom
database_cross_reference: NLM:neural+groove
annotated target: The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds.
annotated property: definition
annotated source: neural groove

neural plate
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
definition: A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube. At NF stage 11.5 is the first indication of neural plate within the sensorial layer of ectoderm. It extends to near the animal pole by NF stage 12.5 and the entire plate is faintly delimited by NF stage 13.
database_cross_reference: AAO:0011072
id: XAO:0000249

Axiom
annotated target: A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube. At NF stage 11.5 is the first indication of neural plate within the sensorial layer of ectoderm. It extends to near the animal pole by NF stage 12.5 and the entire plate is faintly delimited by NF stage 13.
database_cross_reference: ISBN:0815318960
database_cross_reference: OMD:neural+plate
annotated property: definition
annotated source: neural plate

posterior neural tube
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: neural tube
subclass of: Restriction
  on property: develops from
  some values from: chordal neural plate
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
database_cross_reference: AAO:0011082
definition: Posterior segment of the neural tube, which develops into the hindbrain and spinal cord.
id: XAO:0000250

Axiom
annotated target: Posterior segment of the neural tube, which develops into the hindbrain and spinal cord.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: posterior neural tube

visceral pouch 3
type: Class
subclass of: visceral pouch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
database_cross_reference: AAO:0011116
definition: Third of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
id: XAO:0000251
has_exact_synonym: third visceral pouch

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: Third of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
annotated property: definition
annotated source: visceral pouch 3

neurocoel
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
database_cross_reference: AAO:0011073
definition: Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.
id: XAO:0000252

Axiom
annotated target: Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.
database_cross_reference: VHOG:0001119
annotated property: definition
annotated source: neurocoel

non-involuting marginal zone
type: Class
subclass of: marginal zone
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
database_cross_reference: AAO:0010452
definition: Animal portion of the marginal zone of the embryo that spreads in front of the animal cap but does not involute during gastrulation.
has_exact_synonym: NIMZ
id: XAO:0000253

Axiom
annotated target: Animal portion of the marginal zone of the embryo that spreads in front of the animal cap but does not involute during gastrulation.
database_cross_reference: http://worms.zoology.wisc.edu/frogs/glossary.html
annotated property: definition
annotated source: non-involuting marginal zone

visceral pouch 4
type: Class
subclass of: visceral pouch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
database_cross_reference: AAO:0011117
definition: Fourth of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
id: XAO:0000254
has_exact_synonym: fourth visceral pouch

Axiom
annotated target: Fourth of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
database_cross_reference: ISBN:0-226-55763-4
annotated property: definition
annotated source: visceral pouch 4

visceral pouch 5
type: Class
subclass of: visceral pouch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
database_cross_reference: AAO:0011118
definition: Fifth of the pharyngeal (endodermal) evaginations between the visceral arches.
id: XAO:0000255
has_exact_synonym: fifth visceral pouch

Axiom
annotated target: Fifth of the pharyngeal (endodermal) evaginations between the visceral arches.
database_cross_reference: ISBN:0-226-55763-4
annotated property: definition
annotated source: visceral pouch 5

oocyte
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: develops from
  some values from: secondary oogonium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000083
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000092
database_cross_reference: CL:0000023
definition: The developing female gamete, the differentiation of which is classified into six stages: I (pre-vitellogenic), II (early vitellogenic), III (mid-vitellogenic, formation of pigment), IV (polarization along animal-vegetal axis), V (late vitellogenic), and VI (post-vitellogenic, appearance of equatorial band).
id: XAO:0000256

Axiom
database_cross_reference: PMID:4109871
annotated target: The developing female gamete, the differentiation of which is classified into six stages: I (pre-vitellogenic), II (early vitellogenic), III (mid-vitellogenic, formation of pigment), IV (polarization along animal-vegetal axis), V (late vitellogenic), and VI (post-vitellogenic, appearance of equatorial band).
annotated property: definition
annotated source: oocyte

oral evagination
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
definition: An outpocketing of the foregut ventral to the infundibulum and the hypophysis. The walls surrounding this cavity are composed of endoderm.
id: XAO:0000257

Axiom
annotated target: An outpocketing of the foregut ventral to the infundibulum and the hypophysis. The walls surrounding this cavity are composed of endoderm.
database_cross_reference: http://www.uoguelph.ca/zoology/devobio/34mmfrog/db34fg1.htm
annotated property: definition
annotated source: oral evagination

ovary
type: Class
subclass of: gonad
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: female genitalia
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
database_cross_reference: AAO:0000371
definition: Either of paired female reproductive organs involved in production of ova and female sex hormones.
id: XAO:0000258

Axiom
database_cross_reference: AAO:0000371
annotated target: Either of paired female reproductive organs involved in production of ova and female sex hormones.
annotated property: definition
annotated source: ovary

paraxial mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: develops from
  some values from: presumptive paraxial mesoderm
database_cross_reference: AAO:0010568
definition: Area of mesoderm at either side of the midline embryonic notochord that, on segmentation, forms the paired somites.
id: XAO:0000259

Axiom
annotated target: Area of mesoderm at either side of the midline embryonic notochord that, on segmentation, forms the paired somites.
database_cross_reference: OMD:paraxial+mesoderm
annotated property: definition
annotated source: paraxial mesoderm

perivitelline space
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000001
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000092
subclass of: Restriction
  on property: part of
  some values from: zygote
database_cross_reference: AAO:0010329
definition: The space between the zona pellucida and the cell membrane of an oocyte or fertilized ovum.
id: XAO:0000260

Axiom
annotated target: The space between the zona pellucida and the cell membrane of an oocyte or fertilized ovum.
database_cross_reference: http://en.wikipedia.org/wiki/Perivitelline_space
annotated property: definition
annotated source: perivitelline space

pigment layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000047
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: optic vesicle
database_cross_reference: AAO:0010350
definition: Outer layer of the developing optic vesicle, which contains pigmented epithelium.
id: XAO:0000261

Axiom
annotated target: Outer layer of the developing optic vesicle, which contains pigmented epithelium.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: pigment layer

polar body
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: oocyte
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000088
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000083
definition: A small cell formed by the meiotic division of an oocyte.
database_cross_reference: AAO:0010307
id: XAO:0000262

Axiom
annotated target: A small cell formed by the meiotic division of an oocyte.
database_cross_reference: CL:0002090
annotated property: definition
annotated source: polar body

primary oogonium
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000066
subclass of: Restriction
  on property: part of
  some values from: ovary
subclass of: Restriction
  on property: develops from
  some values from: primordial germ cell
definition: A germ cell that is a primordial oocyte in a female and that develops into secondary oogonia by mitotic division.
database_cross_reference: AAO:0010297
id: XAO:0000263
has_related_synonym: primary oogonia

Axiom
annotated target: A germ cell that is a primordial oocyte in a female and that develops into secondary oogonia by mitotic division.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: primary oogonium

Axiom
annotated target: primary oogonia
annotated source: primary oogonium
has_synonym_type: PLURAL
annotated property: has_related_synonym

pronephric mesenchyme
type: Class
subclass of: mesenchyme
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
database_cross_reference: AAO:0011090
definition: Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.
id: XAO:0000264
has_related_synonym: pronephric anlage
has_related_synonym: pronephric bulge
has_related_synonym: pronephric primordium

Axiom
annotated target: Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: pronephric mesenchyme

visceral pouch 6
type: Class
subclass of: visceral pouch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
database_cross_reference: AAO:0011119
definition: Sixth of the pharyngeal (endodermal) evaginations between the visceral arches.
id: XAO:0000265
has_exact_synonym: sixth visceral pouch

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: Sixth of the pharyngeal (endodermal) evaginations between the visceral arches.
annotated property: definition
annotated source: visceral pouch 6

retinal layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000047
subclass of: Restriction
  on property: part of
  some values from: optic vesicle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
database_cross_reference: AAO:0010353
definition: Inner layer of the developing optic vesicle, which contains retinal nerve cells.
id: XAO:0000266

Axiom
annotated target: Inner layer of the developing optic vesicle, which contains retinal nerve cells.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: retinal layer

hypophyseal primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: stomodeal-hypophyseal primordium
definition: The hypophyseal layer that separates from the stomodeal layer of the stomodeal-hypophyseal primordium at NF stage 29 and 30.
id: XAO:0000267

Axiom
annotated target: The hypophyseal layer that separates from the stomodeal layer of the stomodeal-hypophyseal primordium at NF stage 29 and 30.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: hypophyseal primordium

secondary oogonium
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000066
subclass of: Restriction
  on property: develops from
  some values from: primary oogonium
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A type of germ cell that results from the mitotic division of a primary oogonium.
database_cross_reference: AAO:0010299
id: XAO:0000268
has_related_synonym: secondary oogonia

Axiom
annotated target: A type of germ cell that results from the mitotic division of a primary oogonium.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: secondary oogonium

Axiom
annotated target: secondary oogonia
annotated source: secondary oogonium
has_synonym_type: PLURAL
annotated property: has_related_synonym

mouth primordium
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: develops from
  some values from: stomodeal-hypophyseal primordium
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000072
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: alimentary system
definition: Anterior part of the embryonic alimentary canal that is formed as an invagination of the ectoderm and is the future mouth.
id: XAO:0000269
has_broad_synonym: mouth
has_broad_synonym: stomodeal-hypophyseal primordium

Axiom
annotated target: Anterior part of the embryonic alimentary canal that is formed as an invagination of the ectoderm and is the future mouth.
database_cross_reference: UBERON:0000930
annotated property: definition
annotated source: mouth primordium

sensorial layer of neurectoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
definition: Deep layer of the neural ectoderm, which undergoes early neuronal differentiation.
id: XAO:0000270
has_related_synonym: deep layer of neurectoderm

Axiom
annotated target: Deep layer of the neural ectoderm, which undergoes early neuronal differentiation.
database_cross_reference: PMID:11832243
annotated property: definition
annotated source: sensorial layer of neurectoderm

somatic layer of lateral plate mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: develops from
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: lateral plate mesoderm
database_cross_reference: AAO:0011100
definition: Layer of lateral plate mesoderm that forms the future body wall; it underlies the ectoderm.
id: XAO:0000271

Axiom
annotated target: Layer of lateral plate mesoderm that forms the future body wall; it underlies the ectoderm.
database_cross_reference: UBERON:0004871
annotated property: definition
annotated source: somatic layer of lateral plate mesoderm

Jacobson's organ
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: part of
  some values from: olfactory system
subclass of: Restriction
  on property: develops from
  some values from: olfactory organ
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000997
definition: An auxiliary olfactory sense organ involved in the detection of pheromones.
has_exact_synonym: VNO
id: XAO:0000272
has_exact_synonym: organon vomeronasale
has_exact_synonym: vomeronasal organ

Axiom
annotated target: An auxiliary olfactory sense organ involved in the detection of pheromones.
database_cross_reference: WIKI:Vomeronasal_organ
annotated property: definition
annotated source: Jacobson's organ

olfactory organ
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: olfactory system
subclass of: Restriction
  on property: develops from
  some values from: olfactory placode
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
database_cross_reference: AAO:0010180
definition: Organ comprising the specialized structures subserving the function of the sense of smell.
id: XAO:0000273

Axiom
database_cross_reference: BTO:0001772
annotated target: Organ comprising the specialized structures subserving the function of the sense of smell.
annotated property: definition
annotated source: olfactory organ

sperm entry point
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: zygote
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000001
database_cross_reference: AAO:0010330
definition: The point on the surface of the egg at which the sperm enters the egg.
id: XAO:0000274

Axiom
annotated target: The point on the surface of the egg at which the sperm enters the egg.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sperm entry point

olfactory pit
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: develops from
  some values from: olfactory placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000062
subclass of: Restriction
  on property: part of
  some values from: olfactory system
definition: A depression on the head of the embryo that becomes converted into a nasal passage.
database_cross_reference: AAO:0011068
id: XAO:0000275
has_alternative_id: XAO:0004073
has_exact_synonym: nasal pit

Axiom
annotated target: A depression on the head of the embryo that becomes converted into a nasal passage.
database_cross_reference: http://www.merriam-webster.com/medical/olfactory%20pit
annotated property: definition
annotated source: olfactory pit

splanchnic layer of lateral plate mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: develops from
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
database_cross_reference: AAO:0011102
definition: Layer of lateral plate mesoderm that forms the circulatory system and future gut wall; it overlies endoderm.
database_cross_reference: UBERON:0004872
id: XAO:0000276
has_alternative_id: XAO:0004273
has_related_synonym: splanchnic mesoderm
has_related_synonym: visceral mesoderm

Axiom
annotated target: Layer of lateral plate mesoderm that forms the circulatory system and future gut wall; it overlies endoderm.
database_cross_reference: UBERON:0004872
annotated property: definition
annotated source: splanchnic layer of lateral plate mesoderm

choana
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: olfactory placode
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
database_cross_reference: AAO:0000093
definition: The internal nasal passages, aperture or cavity in the roof of the buccopharynx.
id: XAO:0000277
has_related_synonym: choanae
has_related_synonym: internal nares
has_exact_synonym: posterior nasal apperture

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: The internal nasal passages, aperture or cavity in the roof of the buccopharynx.
annotated property: definition
annotated source: choana

Axiom
annotated target: choanae
annotated source: choana
has_synonym_type: PLURAL
annotated property: has_related_synonym

animal part, late involuting
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
subclass of: Restriction
  on property: part of
  some values from: involuting marginal zone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: When the marginal zone mesoderm undergoes involution, where the marginal zone contacts the vegetal base.
id: XAO:0000278

Axiom
annotated target: When the marginal zone mesoderm undergoes involution, where the marginal zone contacts the vegetal base.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: animal part, late involuting

vegetal blastomere
type: Class
subclass of: blastomere
subclass of: Restriction
  on property: develops from
  some values from: vegetal hemisphere
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000019
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000011
database_cross_reference: AAO:0010284
definition: Unpigmented, larger blastomere of the vegetal (lower) hemisphere of the cleaving embryo.
id: XAO:0000279
has_related_synonym: macromere

Axiom
database_cross_reference: ISBN:0471209627
annotated target: Unpigmented, larger blastomere of the vegetal (lower) hemisphere of the cleaving embryo.
annotated property: definition
annotated source: vegetal blastomere

vegetal hemisphere
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: part of
  some values from: zygote
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000021
database_cross_reference: AAO:0010331
definition: Anatomical region relating to the lower, light-colored hemisphere of the egg.
id: XAO:0000280

Axiom
annotated target: Anatomical region relating to the lower, light-colored hemisphere of the egg.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: vegetal hemisphere

vegetal yolk mass
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000022
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000019
database_cross_reference: AAO:0010334
definition: Cell mass in the vegetal region of the embryo that will contribute to endoderm.
id: XAO:0000281
has_exact_synonym: vegetal cell mass

Axiom
annotated target: Cell mass in the vegetal region of the embryo that will contribute to endoderm.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: vegetal yolk mass

visceral pouch
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: part of
  some values from: pharyngeal region
database_cross_reference: AAO:0011113
definition: Pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
id: XAO:0000282
has_related_synonym: visceral pouches

Axiom
annotated target: visceral pouches
annotated source: visceral pouch
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: Pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.
annotated property: definition
annotated source: visceral pouch

pupil
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
definition: A hole located in the center of the iris of the eye that allows light to enter the retina.
database_cross_reference: AAO:0010351
id: XAO:0000283

Axiom
annotated target: A hole located in the center of the iris of the eye that allows light to enter the retina.
database_cross_reference: WIKI:Pupil
annotated property: definition
annotated source: pupil

epibranchial placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: develops from
  some values from: dorsolateral placode region
database_cross_reference: AAO:0011036
definition: The three distinct placodal areas, which develop from the posterior placodal area, and lie ventral to the otic placode and dorsocaudal to the pharyngeal clefts, and contribute to the sensory ganglia and cranial nerves.
id: XAO:0000284

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The three distinct placodal areas, which develop from the posterior placodal area, and lie ventral to the otic placode and dorsocaudal to the pharyngeal clefts, and contribute to the sensory ganglia and cranial nerves.
annotated property: definition
annotated source: epibranchial placode

pronephric nephron
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: pronephric kidney
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
database_cross_reference: AAO:0011091
definition: The structure that is the basic functional unit of the pronephros.
id: XAO:0000285
has_related_synonym: pronephric tubule

Axiom
annotated target: The structure that is the basic functional unit of the pronephros.
database_cross_reference: UBERON:0005309
annotated property: definition
annotated source: pronephric nephron

late proximal tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: pronephric nephron
database_cross_reference: AAO:0011122
has_exact_synonym: PT3
definition: Portion of the pronephric tubule that is immediately posterior to the early proximal tubule and anterior to the early distal tubule.
id: XAO:0000286
has_exact_synonym: late proximal segment
has_exact_synonym: proximal tubule 3

Axiom
database_cross_reference: PMID:15223337
annotated target: Portion of the pronephric tubule that is immediately posterior to the early proximal tubule and anterior to the early distal tubule.
annotated property: definition
annotated source: late proximal tubule

early distal tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: pronephric nephron
database_cross_reference: AAO:0011034
has_exact_synonym: IT1
has_exact_synonym: IT2
definition: Portion of the pronephric tubule that is immediately posterior to the late proximal tubule and anterior to the late distal segment.
id: XAO:0000287
has_exact_synonym: distal early tubule
has_exact_synonym: intermediate tubule
has_exact_synonym: pronephric distal early tubule
has_related_synonym: pronephric early distal tubule

Axiom
database_cross_reference: PMID:15223337
annotated target: Portion of the pronephric tubule that is immediately posterior to the late proximal tubule and anterior to the late distal segment.
annotated property: definition
annotated source: early distal tubule

early proximal tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: pronephric mesenchyme
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: pronephric nephron
database_cross_reference: AAO:0011120
has_exact_synonym: PT2
definition: Portion of the pronephric tubule that is immediately anterior to the late proximal tubule.
id: XAO:0000288

Axiom
database_cross_reference: PMID:15223337
annotated target: Portion of the pronephric tubule that is immediately anterior to the late proximal tubule.
annotated property: definition
annotated source: early proximal tubule

late distal segment
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: pronephric nephron
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
subclass of: Restriction
  on property: develops from
  some values from: pronephric mesenchyme
database_cross_reference: AAO:0011121
has_exact_synonym: DT1
definition: Pronephric segment immediately posterior to the early distal tubule and anterior to the pronehric duct.
id: XAO:0000289

Axiom
database_cross_reference: PMID:15223337
annotated target: Pronephric segment immediately posterior to the early distal tubule and anterior to the pronehric duct.
annotated property: definition
annotated source: late distal segment

pronephric nephron segment S1
type: Class
id: XAO:0000290
deprecated: true

mesonephric mesenchyme
type: Class
subclass of: mesenchyme
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
subclass of: Restriction
  on property: part of
  some values from: mesonephric kidney
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011062
definition: The tissue made up of loosely connected mesenchymal cells in the mesonephros.
id: XAO:0000291

Axiom
database_cross_reference: GO:0061219
annotated target: The tissue made up of loosely connected mesenchymal cells in the mesonephros.
annotated property: definition
annotated source: mesonephric mesenchyme

mesonephric nephron
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: mesonephric kidney
subclass of: Restriction
  on property: develops from
  some values from: mesonephric mesenchyme
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010387
definition: The structure that is the basic functional unit of the kidney.
has_alternative_id: XAO:0000145
id: XAO:0000292
has_related_synonym: nephron

Axiom
database_cross_reference: PMID:9268568
annotated target: The structure that is the basic functional unit of the kidney.
annotated property: definition
annotated source: mesonephric nephron

neural fold
type: Class
id: XAO:0000293
term replaced by: XAO:0004087
deprecated: true

blastocoel
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000023
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: develops from
  some values from: blastocoel anlage
definition: A blastocoel forms during embryogenesis when a zygote (a fertilized ovum) divides into many cells through mitosis. The blastocoel is the cavity of the blastula, a closed space which is invaded by early mesenchyme and later obliterated by the enlarging archenteron.
database_cross_reference: AAO:0010433
id: XAO:0000294
has_exact_synonym: blastocele
has_related_synonym: blastocyst cavity
has_related_synonym: cleavage cavity
has_related_synonym: segmentation cavity

Axiom
annotated target: A blastocoel forms during embryogenesis when a zygote (a fertilized ovum) divides into many cells through mitosis. The blastocoel is the cavity of the blastula, a closed space which is invaded by early mesenchyme and later obliterated by the enlarging archenteron.
database_cross_reference: ISBN:0-02-377110-0
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: blastocoel

central endoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000026
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
subclass of: Restriction
  on property: part of
  some values from: endoderm
definition: The portion of endoderm between dorsal and ventral blastopore lips, and extending towards to the blastocoel.
id: XAO:0000295
has_related_synonym: endodermal yolk mass
has_related_synonym: vegetal endodermal core

Axiom
annotated target: The portion of endoderm between dorsal and ventral blastopore lips, and extending towards to the blastocoel.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: central endoderm

vegetal
type: Class
subclass of: anatomical direction
definition: Anatomical direction relating to the vegetal pole or hemisphere.
id: XAO:0000296
in_subset: anatomical site slim

Axiom
annotated target: Anatomical direction relating to the vegetal pole or hemisphere.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: vegetal

animal
type: Class
subclass of: anatomical direction
definition: Anatomical direction relating to the animal pole or hemisphere.
id: XAO:0000297
has_related_synonym: animal hemisphere
in_subset: anatomical site slim

Axiom
annotated target: Anatomical direction relating to the animal pole or hemisphere.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: animal

dorsal
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting the back or upper surface of the body.
id: XAO:0000298
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Dorsal
annotated target: Spatial concept denoting the back or upper surface of the body.
annotated property: definition
annotated source: dorsal

ventral
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting the underside or lower surface of the body.
id: XAO:0000299
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Ventral
annotated target: Spatial concept denoting the underside or lower surface of the body.
annotated property: definition
annotated source: ventral

superficial
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting only the surface of the body.
id: XAO:0000300
in_subset: anatomical site slim

Axiom
annotated target: Spatial concept denoting only the surface of the body.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: superficial

deep
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting extension relatively far inward.
id: XAO:0000301
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Deep
annotated target: Spatial concept denoting extension relatively far inward.
annotated property: definition
annotated source: deep

dorso-lateral
type: Class
subclass of: anatomical direction
definition: Spatial concept pertaining to the back of the body and to the side.
id: XAO:0000302
in_subset: anatomical site slim

Axiom
annotated target: Spatial concept pertaining to the back of the body and to the side.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/dorsolateral
annotated property: definition
annotated source: dorso-lateral

ventro-lateral
type: Class
subclass of: anatomical direction
definition: Spatial concept pertaining to the part of the body opposite the back and away from the midline.
id: XAO:0000303
in_subset: anatomical site slim

Axiom
annotated target: Spatial concept pertaining to the part of the body opposite the back and away from the midline.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/ventrolateral
annotated property: definition
annotated source: ventro-lateral

lateral
type: Class
subclass of: anatomical direction
definition: Spatial concept pertaining to being situated at or extending to the side.
id: XAO:0000304
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Lateral
annotated target: Spatial concept pertaining to being situated at or extending to the side.
annotated property: definition
annotated source: lateral

cranial placode
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: part of
  some values from: neuroectoderm
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000024
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000054
subclass of: Restriction
  on property: develops from
  some values from: animal cap inner layer
definition: A localized ectodermal thickening that develops by apicobasal elongation of cuboidal cells in the inner layer of the ectoderm in the head of the embryos, and is involved in formation of sense organs.
database_cross_reference: AAO:0010466
id: XAO:0000305
has_related_synonym: cranial placodes

Axiom
annotated target: cranial placodes
annotated source: cranial placode
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: A localized ectodermal thickening that develops by apicobasal elongation of cuboidal cells in the inner layer of the ectoderm in the head of the embryos, and is involved in formation of sense organs.
database_cross_reference: UBERON:0002546
annotated property: definition
annotated source: cranial placode

floor plate
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: develops from
  some values from: notoplate
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: spinal cord
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0011041
definition: Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories.
id: XAO:0000306
has_exact_synonym: floorplate
has_related_synonym: spinal cord floor

Axiom
database_cross_reference: GO:0021508
annotated target: Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories.
database_cross_reference: PMID:15738958
annotated property: definition
annotated source: floor plate

anterior neural tube
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: neural tube
subclass of: Restriction
  on property: develops from
  some values from: pre-chordal neural plate
database_cross_reference: AAO:0011012
definition: Anterior segment of the neural tube, which develops into the forebrain and midbrain.
id: XAO:0000307

Axiom
annotated target: Anterior segment of the neural tube, which develops into the forebrain and midbrain.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: anterior neural tube

marginal zone (sensu neural)
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
definition: Region of the neural tube that will become the white matter of the nervous system.
id: XAO:0000309
in_subset: anatomical site slim

Axiom
database_cross_reference: ISBN:0393974308
annotated target: Region of the neural tube that will become the white matter of the nervous system.
annotated property: definition
annotated source: marginal zone (sensu neural)

anterior neural fold
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: neural fold
subclass of: Restriction
  on property: part of
  some values from: pre-chordal neural plate
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
definition: The anterior U-shaped portion of the neural folds, the two longitudinal dorsal ridges, caused by a folding up of the ectoderm, that make their appearance on either side of the middle line of the early neural embryo.
id: XAO:0000310

Axiom
annotated target: The anterior U-shaped portion of the neural folds, the two longitudinal dorsal ridges, caused by a folding up of the ectoderm, that make their appearance on either side of the middle line of the early neural embryo.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: anterior neural fold

lateral plate mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
database_cross_reference: AAO:0010574
definition: Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures.
id: XAO:0000311

Axiom
annotated target: Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures.
database_cross_reference: UBERON:0003081
annotated property: definition
annotated source: lateral plate mesoderm

head somite
type: Class
subclass of: somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
definition: Any of the transient, degenerating occipital somites.
id: XAO:0000313
has_related_synonym: cranial somite
has_related_synonym: occipital somite

Axiom
annotated target: Any of the transient, degenerating occipital somites.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head somite

trunk somite
type: Class
subclass of: somite
subclass of: Restriction
  on property: part of
  some values from: trunk
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: A somite located posterior to the head and anterior to the tail.
database_cross_reference: AAO:0010385
id: XAO:0000314

Axiom
annotated target: A somite located posterior to the head and anterior to the tail.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite

myotome
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
database_cross_reference: AAO:0011067
definition: Somitic compartment that is a precursor of muscle.
id: XAO:0000315
has_related_synonym: myotomes

Axiom
database_cross_reference: PMID:17313522
annotated target: Somitic compartment that is a precursor of muscle.
annotated property: definition
annotated source: myotome

Axiom
annotated target: myotomes
annotated source: myotome
has_synonym_type: PLURAL
annotated property: has_related_synonym

epicardium
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: develops from
  some values from: fused heart primordium
database_cross_reference: AAO:0010409
definition: The inner layer of the pericardium that is in contact with the surface of the heart.
id: XAO:0000316
has_exact_synonym: heart epicardium

Axiom
database_cross_reference: AAO:0010409
annotated target: The inner layer of the pericardium that is in contact with the surface of the heart.
annotated property: definition
annotated source: epicardium

glomus
type: Class
subclass of: glomerulus
subclass of: Restriction
  on property: part of
  some values from: pronephric kidney
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000067
subclass of: Restriction
  on property: develops from
  some values from: glomeral mesenchyme
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
database_cross_reference: AAO:0011049
comment: Properly called a glomus as it extends over multiple body segments.
definition: The filtration unit of the pronephric kidney. A glomus is a glomerulus that spans more than one body segment. It is the vascularized filter of the pronephric kidney. Blood is filtered through the glomus and the filtrate deposited into the coelom early in development, or the nephrocoel later in development. The Xenopus glomus contains podocytes with well developed foot processes that are anatomically indistinguishable from the podocytes of adult glomeruli. The two glomera are linked via a narrow bridge called the glomeral nexus.
id: XAO:0000318
has_related_synonym: corpuscle
has_related_synonym: glomera
has_related_synonym: glomerulus

Axiom
annotated target: glomera
annotated source: glomus
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
database_cross_reference: PMID:9268568
annotated target: The filtration unit of the pronephric kidney. A glomus is a glomerulus that spans more than one body segment. It is the vascularized filter of the pronephric kidney. Blood is filtered through the glomus and the filtrate deposited into the coelom early in development, or the nephrocoel later in development. The Xenopus glomus contains podocytes with well developed foot processes that are anatomically indistinguishable from the podocytes of adult glomeruli. The two glomera are linked via a narrow bridge called the glomeral nexus.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: glomus

trunk neural crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: part of
  some values from: neural crest
database_cross_reference: AAO:0010582
has_exact_synonym: TNC
definition: Trunk neural crest cells migrate along two major pathways: through the somites, to populate the skin where they give rise to pigment cells; cells migrating along the lateral pathway generate sensory and sympathetic ganglia and adrenal chromaffin cells, among others.
id: XAO:0000319
has_related_synonym: trunk crest

Axiom
database_cross_reference: ISBN:0878933840
annotated target: Trunk neural crest cells migrate along two major pathways: through the somites, to populate the skin where they give rise to pigment cells; cells migrating along the lateral pathway generate sensory and sympathetic ganglia and adrenal chromaffin cells, among others.
annotated property: definition
annotated source: trunk neural crest

sensorial layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: The inner layer of ectoderm.
id: XAO:0000320

Axiom
annotated target: The inner layer of ectoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: sensorial layer

profundus ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: profundal placode
definition: Type of ganglion that is separate distally from the trigeminal ganglia; they become fused at their proximal end as they condense.
id: XAO:0000323
has_related_synonym: cranial ganglion
has_related_synonym: profundus ganglia

Axiom
annotated target: profundus ganglia
annotated source: profundus ganglion
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
database_cross_reference: PMID:21452441
annotated target: Type of ganglion that is separate distally from the trigeminal ganglia; they become fused at their proximal end as they condense.
annotated property: definition
annotated source: profundus ganglion

hypobranchial placode
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: develops from
  some values from: dorsolateral placode region
definition: A unique type of neurogenic placode, located ventral and caudal to the 2nd and 3rd pharyngeal pouches, which gives rise to small hypobranchial ganglia of yet unknown function.
id: XAO:0000324

Axiom
annotated target: A unique type of neurogenic placode, located ventral and caudal to the 2nd and 3rd pharyngeal pouches, which gives rise to small hypobranchial ganglia of yet unknown function.
database_cross_reference: PMID:12712315
annotated property: definition
annotated source: hypobranchial placode

left spleen primordium
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: develops from
  some values from: splanchnic layer of lateral plate mesoderm
subclass of: Restriction
  on property: part of
  some values from: immune system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Primordium of the spleen, which goes on to form the spleen proper, while the right splenic promordium degenerates.
id: XAO:0000326
has_broad_synonym: spleen

Axiom
annotated target: Primordium of the spleen, which goes on to form the spleen proper, while the right splenic promordium degenerates.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: left spleen primordium

right spleen primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: immune system
subclass of: Restriction
  on property: develops from
  some values from: splanchnic layer of lateral plate mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Transient splenic primordia that degenerates by NF stage 40.
id: XAO:0000327
has_broad_synonym: spleen

Axiom
annotated target: Transient splenic primordia that degenerates by NF stage 40.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: right spleen primordium

spleen
type: Class
subclass of: viscus
subclass of: compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: left spleen primordium
subclass of: Restriction
  on property: part of
  some values from: immune system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
database_cross_reference: AAO:0010395
definition: Internal lymphoid organ derived from left spleen primordia beginning at NF stage 48.
id: XAO:0000328

Axiom
annotated target: Internal lymphoid organ derived from left spleen primordia beginning at NF stage 48.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: spleen

coelomic epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: somatic layer of lateral plate mesoderm
subclass of: Restriction
  on property: develops from
  some values from: splanchnic layer of lateral plate mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: The epithelial lining of the coelom.
id: XAO:0000329

Axiom
annotated target: The epithelial lining of the coelom.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: coelomic epithelium

Mullerian duct
type: Class
subclass of: duct
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000076
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010141
definition: Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).
id: XAO:0000330

Axiom
database_cross_reference: AAO:0010141
annotated target: Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).
annotated property: definition
annotated source: Mullerian duct

mesonephric early proximal tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: mesonephric tubule
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: develops from
  some values from: mesonephric nephron
database_cross_reference: AAO:0010392
definition: Structure that is equivalent to the convoluted proximal tubule of metanephric nephrons.
id: XAO:0000331

Axiom
annotated target: Structure that is equivalent to the convoluted proximal tubule of metanephric nephrons.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: mesonephric early proximal tubule

mesonephric late proximal tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: mesonephric tubule
subclass of: Restriction
  on property: develops from
  some values from: mesonephric nephron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
database_cross_reference: AAO:0010394
definition: Structure that is the mesonephros nephron's equivalent to the straight proximal segment of a metanephric nephron.
id: XAO:0000332
has_related_synonym: opisthonephros
has_related_synonym: proximal straight segment

Axiom
annotated target: Structure that is the mesonephros nephron's equivalent to the straight proximal segment of a metanephric nephron.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: mesonephric late proximal tubule

mesonephric early distal tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: mesonephric nephron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: mesonephric tubule
database_cross_reference: AAO:0010391
definition: The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons.
id: XAO:0000333
has_related_synonym: ascending limb
has_related_synonym: straight distal segment

Axiom
annotated target: The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: mesonephric early distal tubule

mesonephric late distal segment
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: develops from
  some values from: mesonephric nephron
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: mesonephric tubule
database_cross_reference: AAO:0010393
definition: The site of bicarbonate resorption in the adult kidney. It is equivalent to the convoluted distal segment of metanephric nephrons.
id: XAO:0000334

Axiom
annotated target: The site of bicarbonate resorption in the adult kidney. It is equivalent to the convoluted distal segment of metanephric nephrons.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: mesonephric late distal segment

fused heart primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: develops from
  some values from: cardiac mesoderm
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000043
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
database_cross_reference: AAO:0011044
definition: The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They will give rise to the endocardium at NF stage 27&28.
id: XAO:0000336
has_broad_synonym: heart
has_related_synonym: heart primordia
has_related_synonym: heart primordium

Axiom
annotated target: The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They will give rise to the endocardium at NF stage 27&28.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: fused heart primordium

endocardial tube
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: develops from
  some values from: endocardium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: heart
database_cross_reference: AAO:0010411
definition: Regions in the embryo that consists of precursor cells for the development of the embryonic heart.
id: XAO:0000337
has_related_synonym: heart tube

Axiom
annotated target: Regions in the embryo that consists of precursor cells for the development of the embryonic heart.
database_cross_reference: http://en.wikipedia.org/wiki/Endocardial_heart_tubes
annotated property: definition
annotated source: endocardial tube

ventral aorta
type: Class
subclass of: aorta
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: develops from
  some values from: endocardial tube
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010412
definition: The outlet of the embryonic heart; lies in the floor of the pharynx and conducts blood from the bulbus arteriosis to the aortic arches (1-6).
id: XAO:0000338

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The outlet of the embryonic heart; lies in the floor of the pharynx and conducts blood from the bulbus arteriosis to the aortic arches (1-6).
annotated property: definition
annotated source: ventral aorta

left channel of ventral aorta
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: develops from
  some values from: ventral aorta
database_cross_reference: AAO:0010413
definition: Of the paired ventral aortas in the tadpole, the one that branches into the left aortic arches.
id: XAO:0000339

Axiom
annotated target: Of the paired ventral aortas in the tadpole, the one that branches into the left aortic arches.
database_cross_reference: PMID:8928932
annotated property: definition
annotated source: left channel of ventral aorta

right channel of ventral aorta
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: develops from
  some values from: ventral aorta
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0010424
definition: Of the paired ventral aortas in the tadpole, the one that branches into the right aortic arches.
id: XAO:0000340

Axiom
annotated target: Of the paired ventral aortas in the tadpole, the one that branches into the right aortic arches.
database_cross_reference: PMID:8928932
annotated property: definition
annotated source: right channel of ventral aorta

aortic arch
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: left channel of ventral aorta
subclass of: Restriction
  on property: develops from
  some values from: right channel of ventral aorta
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0010414
definition: One of a series of six paired embryological vascular structures which give rise to several major arteries.
id: XAO:0000341
has_related_synonym: aortic arches

Axiom
annotated target: One of a series of six paired embryological vascular structures which give rise to several major arteries.
database_cross_reference: UBERON:0004363
annotated property: definition
annotated source: aortic arch

Axiom
annotated target: aortic arches
annotated source: aortic arch
has_synonym_type: PLURAL
annotated property: has_related_synonym

aortic arch 1
type: Class
subclass of: aortic arch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
database_cross_reference: AAO:0010415
definition: The anterior member of a series of six paired arterial connections between the dorsal and ventral aortae. Aortic arch 1 that is part of mandibular arch.
id: XAO:0000342
has_exact_synonym: first aortic arch

Axiom
annotated target: The anterior member of a series of six paired arterial connections between the dorsal and ventral aortae. Aortic arch 1 that is part of mandibular arch.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: aortic arch 1

aortic arch 2
type: Class
subclass of: aortic arch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0010418
definition: The second in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 2 that is part of hyoid arch.
id: XAO:0000343
has_exact_synonym: second aortic arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The second in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 2 that is part of hyoid arch.
annotated property: definition
annotated source: aortic arch 2

aortic arch 3
type: Class
subclass of: aortic arch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
database_cross_reference: AAO:0010419
definition: The third in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 3 lies within the 3rd branchial arch and branches directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.
id: XAO:0000344
has_exact_synonym: third aortic arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The third in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 3 lies within the 3rd branchial arch and branches directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.
annotated property: definition
annotated source: aortic arch 3

external carotid artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: aortic arch 1
subclass of: Restriction
  on property: part of
  some values from: filter chamber
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
database_cross_reference: AAO:0010416
definition: The artery which arises from aortic arch 1 at NF stage 45 and delivers blood to the filter apparatus. It is visible as a bilateral pair of vessels on the ventral surface of the head, running between the heart and the tip of the jaw.
id: XAO:0000345

Axiom
database_cross_reference: PMID:12606281
annotated target: The artery which arises from aortic arch 1 at NF stage 45 and delivers blood to the filter apparatus. It is visible as a bilateral pair of vessels on the ventral surface of the head, running between the heart and the tip of the jaw.
annotated property: definition
annotated source: external carotid artery

larval aorta
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: aortic arch 3
subclass of: Restriction
  on property: develops from
  some values from: dorsal aorta
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0010423
definition: The aorta of a postembryonic, hatched or immature tadpole, prior to metamorphosis.
id: XAO:0000349

Axiom
annotated target: The aorta of a postembryonic, hatched or immature tadpole, prior to metamorphosis.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: larval aorta

secondary vessel
type: Class
id: XAO:0000351
deprecated: true

aortic arch 5
type: Class
subclass of: aortic arch
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
database_cross_reference: AAO:0010421
definition: The fifth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 5 artery is paired and has a common trunk with aortic arch 6 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. Aortic arches 5 and 6 supply the trunk and tail with oxygenated blood.
id: XAO:0000352
has_exact_synonym: fifth aortic arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The fifth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 5 artery is paired and has a common trunk with aortic arch 6 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. Aortic arches 5 and 6 supply the trunk and tail with oxygenated blood.
annotated property: definition
annotated source: aortic arch 5

aortic arch 6
type: Class
subclass of: aortic arch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
database_cross_reference: AAO:0010422
definition: The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood.
id: XAO:0000353
has_exact_synonym: sixth aortic arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood.
annotated property: definition
annotated source: aortic arch 6

posterior palatine artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: aortic arch 1
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: internal carotid artery
database_cross_reference: AAO:0010417
definition: One of three branches of the internal carotid artery, the palatine artery supplies the mouth region.
id: XAO:0000354

Axiom
annotated target: One of three branches of the internal carotid artery, the palatine artery supplies the mouth region.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: posterior palatine artery

aortic arch 4
type: Class
subclass of: aortic arch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0010420
definition: The forth in a series paired arterial connections between the dorsal and ventral aortae, lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.
id: XAO:0000355
has_exact_synonym: fourth aortic arch
has_related_synonym: systemic arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The forth in a series paired arterial connections between the dorsal and ventral aortae, lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.
annotated property: definition
annotated source: aortic arch 4

vascular endothelium
type: Class
subclass of: simple squamous epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: intermediate mesoderm
definition: Simple squamous epithelium which lines blood and lymphatic vessels and the heart.
database_cross_reference: UBERON:0004638
id: XAO:0000356
has_related_synonym: vascular endothelia

Axiom
annotated target: Simple squamous epithelium which lines blood and lymphatic vessels and the heart.
database_cross_reference: ZFA:0001639
annotated property: definition
annotated source: vascular endothelium

Axiom
annotated target: vascular endothelia
annotated source: vascular endothelium
has_synonym_type: PLURAL
annotated property: has_related_synonym

arterial endothelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: vascular endothelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: artery
database_cross_reference: AAO:0011013
definition: The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall.
id: XAO:0000357
has_related_synonym: endothelium of artery

Axiom
annotated target: The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: arterial endothelium

venous endothelium
type: Class
subclass of: simple squamous epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: vein
subclass of: Restriction
  on property: develops from
  some values from: vascular endothelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0011110
definition: Simple squamous epithelium which lines the veins.
id: XAO:0000358

Axiom
annotated target: Simple squamous epithelium which lines the veins.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: venous endothelium

arteria iliaca communis
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: develops from
  some values from: dorsal aorta
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000061
subclass of: Restriction
  on property: ends during
  some values from: death
definition: The blood vessel that bifurcates from the aorta, and supplies the abdominal and pelvic regions.
database_cross_reference: UBERON:0001191
id: XAO:0000361
has_exact_synonym: common iliac artery

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The blood vessel that bifurcates from the aorta, and supplies the abdominal and pelvic regions.
annotated property: definition
annotated source: arteria iliaca communis

coeliaco-mesenteric artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: dorsal aorta
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
database_cross_reference: AAO:0010499
definition: Artery consisting of many branches which supply blood to various organs in the viscus. One of the major blood vessels, branching off the dorsal aorta and supplying the embryonic foregut organs- liver, stomach, intestine, spleen and pancreas.
id: XAO:0000362

Axiom
database_cross_reference: AAO:0010499
annotated target: Artery consisting of many branches which supply blood to various organs in the viscus. One of the major blood vessels, branching off the dorsal aorta and supplying the embryonic foregut organs- liver, stomach, intestine, spleen and pancreas.
database_cross_reference: ISBN:0-07-017977-8
annotated property: definition
annotated source: coeliaco-mesenteric artery

occipitovertebral artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: dorsal aorta
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
definition: One of paired arteries that extends dorsally from the systemic arch to supply the muscles of the jaw and back.
id: XAO:0000363

Axiom
database_cross_reference: ISBN:0801836018
annotated target: One of paired arteries that extends dorsally from the systemic arch to supply the muscles of the jaw and back.
annotated property: definition
annotated source: occipitovertebral artery

caudal artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: dorsal aorta
subclass of: Restriction
  on property: part of
  some values from: tail vasculature
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0011023
has_exact_synonym: CA
definition: The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis.
id: XAO:0000364

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis.
annotated property: definition
annotated source: caudal artery

arteria subclavia
type: Class
subclass of: artery
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: occipitovertebral artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
definition: Artery that branches from either side of the dorsal aorta and delivers blood to the musculature of the shoulder region.
database_cross_reference: UBERON:0001533
id: XAO:0000365
has_exact_synonym: subclavian artery

Axiom
annotated target: Artery that branches from either side of the dorsal aorta and delivers blood to the musculature of the shoulder region.
database_cross_reference: ISBN:0-07-017977-8
annotated property: definition
annotated source: arteria subclavia

internal carotid artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: develops from
  some values from: dorsal aorta
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
database_cross_reference: AAO:0011054
has_exact_synonym: ICA
definition: One of the major arteries of the head, it is the as the cranial continuation of the aortic arches and the dorsal aorta. It curves ventrally before resuming a dorsal course as it enters the head proper, and it lies ventral to the internal jugular vein. The internal carotid artery gives off palatine, ophthalmic, and cerebral branches by stage NF stage 41.
id: XAO:0000366

Axiom
annotated target: One of the major arteries of the head, it is the as the cranial continuation of the aortic arches and the dorsal aorta. It curves ventrally before resuming a dorsal course as it enters the head proper, and it lies ventral to the internal jugular vein. The internal carotid artery gives off palatine, ophthalmic, and cerebral branches by stage NF stage 41.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: internal carotid artery

cerebral artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: internal carotid artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: internal carotid artery
database_cross_reference: AAO:0010493
definition: The anterior continuation of the internal carotid artery, which gives off the nasociliary artery anterior to the eye.
id: XAO:0000367

Axiom
database_cross_reference: PMID:12606281
annotated target: The anterior continuation of the internal carotid artery, which gives off the nasociliary artery anterior to the eye.
annotated property: definition
annotated source: cerebral artery

ophthalmic artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: internal carotid artery
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A branch of the internal carotid artery that delivers blood to the eye. Together with the opthalmic vein, form a double ring encircling the eye and retina. It enters the eye obliquely by crossing over the ophthalmic vein and the internal jugular vein.
database_cross_reference: AAO:0010497
id: XAO:0000368

Axiom
annotated target: A branch of the internal carotid artery that delivers blood to the eye. Together with the opthalmic vein, form a double ring encircling the eye and retina. It enters the eye obliquely by crossing over the ophthalmic vein and the internal jugular vein.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: ophthalmic artery

anterior palatine artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: internal carotid artery
subclass of: Restriction
  on property: develops from
  some values from: internal carotid artery
definition: One of three branches of the internal carotid artery, the palatine artery supplies the mouth region.
id: XAO:0000369

Axiom
annotated target: One of three branches of the internal carotid artery, the palatine artery supplies the mouth region.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: anterior palatine artery

arteria mesenterica posterior
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000062
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: arteria iliaca communis
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
definition: The artery that supplies the network of blood vessels (the mesentry) to the large intestine.
database_cross_reference: UBERON:0005616
id: XAO:0000370
has_exact_synonym: posterior mesenteric artery

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The artery that supplies the network of blood vessels (the mesentry) to the large intestine.
annotated property: definition
annotated source: arteria mesenterica posterior

right lymph heart
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: lymphatic system
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
definition: Lymph hearts are pulsatile organs, present in lower vertebrates, that function to propel lymph into the venous system. Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43.
id: XAO:0000371

Axiom
annotated target: Lymph hearts are pulsatile organs, present in lower vertebrates, that function to propel lymph into the venous system. Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43.
database_cross_reference: PMID:12606281
database_cross_reference: PMID:20067786
annotated property: definition
annotated source: right lymph heart

left lymph heart
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: part of
  some values from: lymphatic system
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Lymph hearts are pulsatile organs, present in lower vertebrates, that function to propel lymph into the venous system. Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43.
id: XAO:0000372

Axiom
annotated target: Lymph hearts are pulsatile organs, present in lower vertebrates, that function to propel lymph into the venous system. Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43.
database_cross_reference: PMID:12606281
database_cross_reference: PMID:20067786
annotated property: definition
annotated source: left lymph heart

duct of Cuvier
type: Class
subclass of: vein
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
database_cross_reference: AAO:0011033
definition: Bilaterally paired longitudinal vein; the anterior cardinal returns blood from the head, and the posterior cardinal returns it from the trunk; these two vessels join together on each side as the common cardinal vein, also known as the duct of Cuvier that leads to the heart's sinus venosus.
id: XAO:0000373
has_related_synonym: common cardinal vein

Axiom
annotated target: Bilaterally paired longitudinal vein; the anterior cardinal returns blood from the head, and the posterior cardinal returns it from the trunk; these two vessels join together on each side as the common cardinal vein, also known as the duct of Cuvier that leads to the heart's sinus venosus.
database_cross_reference: ZFA:0000186
annotated property: definition
annotated source: duct of Cuvier

dorsal lymph space
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: develops from
  some values from: right lymph heart
subclass of: Restriction
  on property: part of
  some values from: lymphatic system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
definition: Large subdermal lymph-containing space located dorsally near the last vertebrae.
id: XAO:0000374

Axiom
annotated target: Large subdermal lymph-containing space located dorsally near the last vertebrae.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: dorsal lymph space

lymph vessel
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: develops from
  some values from: left lymph heart
subclass of: Restriction
  on property: develops from
  some values from: dorsal lymph space
subclass of: Restriction
  on property: part of
  some values from: lymphatic system
subclass of: Restriction
  on property: part of
  some values from: circulatory system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
definition: A vessel that contains or conveys lymph.
database_cross_reference: AAO:0011005
id: XAO:0000375
has_related_synonym: lymphatic vessel

Axiom
annotated target: A vessel that contains or conveys lymph.
database_cross_reference: AAO:0011005
annotated property: definition
annotated source: lymph vessel

omphalomesenteric vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
definition: Any of the veins in the embryo that return blood from the yolk sac to the heart or later to the portal vein.
id: XAO:0000376

Axiom
annotated target: Any of the veins in the embryo that return blood from the yolk sac to the heart or later to the portal vein.
database_cross_reference: http://www.merriam-webster.com/medical/omphalomesenteric%20vein
annotated property: definition
annotated source: omphalomesenteric vein

capillary system of liver
type: Class
subclass of: capillary
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: develops from
  some values from: omphalomesenteric vein
subclass of: Restriction
  on property: part of
  some values from: liver
database_cross_reference: AAO:0010404
definition: The smallest of the blood vessels, parts of the microcirculation, of the liver.
id: XAO:0000377
has_exact_synonym: liver capillary

Axiom
annotated target: The smallest of the blood vessels, parts of the microcirculation, of the liver.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: capillary system of liver

musculoabdominal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Ventrolateral component of the external jugular vein.
id: XAO:0000378

Axiom
database_cross_reference: PMID:12606281
annotated target: Ventrolateral component of the external jugular vein.
annotated property: definition
annotated source: musculoabdominal vein

external jugular vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head vasculature
database_cross_reference: AAO:0010508
definition: One of the bilateral pairs of vessels are clearly seen on the ventral surface of the head, running between the heart and the tip of the jaw, and drains the filter apparatus. This vein is more developed by NF stage 45, when it crosses the head dorsolaterally to drain into the Duct of Cuvier and pronephric sinus.
id: XAO:0000379
has_exact_synonym: external jugular

Axiom
annotated target: One of the bilateral pairs of vessels are clearly seen on the ventral surface of the head, running between the heart and the tip of the jaw, and drains the filter apparatus. This vein is more developed by NF stage 45, when it crosses the head dorsolaterally to drain into the Duct of Cuvier and pronephric sinus.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: external jugular vein

lateral postcardinal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000056
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Vein that first appears as disconnected portions lateral to the Wolffian ducts at NF stage 44, gradually becoming continuous. They come into communication with the medial postcardinals at the kidney sinus.
id: XAO:0000380

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Vein that first appears as disconnected portions lateral to the Wolffian ducts at NF stage 44, gradually becoming continuous. They come into communication with the medial postcardinals at the kidney sinus.
annotated property: definition
annotated source: lateral postcardinal vein

mesonephric sinus
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: develops from
  some values from: lateral postcardinal vein
database_cross_reference: AAO:0011063
definition: Sinus that surrounds the mesonephric tubules and puts lateral and medial postcardinal veins into communication with each other.
id: XAO:0000381

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Sinus that surrounds the mesonephric tubules and puts lateral and medial postcardinal veins into communication with each other.
annotated property: definition
annotated source: mesonephric sinus

internal jugular vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
definition: The main dorsal head vein, it drains into the Duct of Cuvier, and collects blood from the dorsal jaw region, cerebral veins, the ophthalmic vein and the short pharyngeal vein. It forms loop around the olfactory bulb by NF stage 43.
id: XAO:0000382

Axiom
database_cross_reference: PMID:12606281
annotated target: The main dorsal head vein, it drains into the Duct of Cuvier, and collects blood from the dorsal jaw region, cerebral veins, the ophthalmic vein and the short pharyngeal vein. It forms loop around the olfactory bulb by NF stage 43.
annotated property: definition
annotated source: internal jugular vein

anterior cardinal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: develops from
  some values from: cardinal vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
database_cross_reference: AAO:0011011
has_exact_synonym: ACV
definition: The anterior cardinal vein returns blood from the dorsal head and drains into the duct of Cuvier via the pronephric sinus.
id: XAO:0000383

Axiom
database_cross_reference: PMID:12606281
annotated target: The anterior cardinal vein returns blood from the dorsal head and drains into the duct of Cuvier via the pronephric sinus.
annotated property: definition
annotated source: anterior cardinal vein

medial cardinal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: develops from
  some values from: cardinal vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
definition: Vein that gives rise to the interrenal vein and pronephric sinus.
id: XAO:0000384

Axiom
annotated target: Vein that gives rise to the interrenal vein and pronephric sinus.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: medial cardinal vein

pronephric sinus
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: pronephric kidney
subclass of: Restriction
  on property: develops from
  some values from: anterior cardinal vein
subclass of: Restriction
  on property: develops from
  some values from: medial cardinal vein
subclass of: Restriction
  on property: develops from
  some values from: duct of Cuvier
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0011092
definition: The pronephric sinus drains into the heart via the Duct of Cuvier at stage 33&34. It is a system of vessels that initially swell from where the anterior and posterior cardinal veins meet before draining into the Duct of Cuvier ( the common cardinal vein), and then continue to narrow and fold into an characteristic S-shape by NF stage 37 and 38. It continues to loop on itself, at first a loose, then a dense knot of many vessels by NF stage 45.
id: XAO:0000385

Axiom
database_cross_reference: PMID:12606281
annotated target: The pronephric sinus drains into the heart via the Duct of Cuvier at stage 33&34. It is a system of vessels that initially swell from where the anterior and posterior cardinal veins meet before draining into the Duct of Cuvier ( the common cardinal vein), and then continue to narrow and fold into an characteristic S-shape by NF stage 37 and 38. It continues to loop on itself, at first a loose, then a dense knot of many vessels by NF stage 45.
annotated property: definition
annotated source: pronephric sinus

interrenal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: medial cardinal vein
definition: Vein formed from fusion of the posterior cardinal veins and that extends caudally.
id: XAO:0000386

Axiom
database_cross_reference: ISBN:0226557626
annotated target: Vein formed from fusion of the posterior cardinal veins and that extends caudally.
annotated property: definition
annotated source: interrenal vein

hepatic vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
database_cross_reference: AAO:0010216
definition: Vein that carries blood away from the liver.
id: XAO:0000387

Axiom
annotated target: Vein that carries blood away from the liver.
database_cross_reference: ZFA:0000670
annotated property: definition
annotated source: hepatic vein

posterior vena cava
type: Class
subclass of: vein
subclass of: Restriction
  on property: develops from
  some values from: interrenal vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
subclass of: Restriction
  on property: develops from
  some values from: hepatic vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011083
definition: Vein that carries de-oxygenated blood from the posterior part of the body to the sinus venosus.
id: XAO:0000388

Axiom
annotated target: Vein that carries de-oxygenated blood from the posterior part of the body to the sinus venosus.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: posterior vena cava

gastric vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
database_cross_reference: AAO:0011046
definition: One of the veins of the alimentary system. The subintestinal vein is on the right side of the gut and drains the gastric vein on its right side by NF stage 43. The gastric veins carry blood low in oxygen from the surface of the stomach, draining into the left omphalomesenteric vein.
id: XAO:0000389

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: One of the veins of the alimentary system. The subintestinal vein is on the right side of the gut and drains the gastric vein on its right side by NF stage 43. The gastric veins carry blood low in oxygen from the surface of the stomach, draining into the left omphalomesenteric vein.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: gastric vein

caudal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: develops from
  some values from: interrenal vein
subclass of: Restriction
  on property: part of
  some values from: tail vasculature
database_cross_reference: AAO:0011025
has_exact_synonym: CV
definition: Vein in the tail returning blood from the trunk and tail to the heart, leads directly into the posterior cardinal vein in the posterior trunk.
id: XAO:0000390

Axiom
annotated target: Vein in the tail returning blood from the trunk and tail to the heart, leads directly into the posterior cardinal vein in the posterior trunk.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: caudal vein

subinterstitial vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: Vein that carries away fluid in the interstitial spaces.
id: XAO:0000391

Axiom
annotated target: Vein that carries away fluid in the interstitial spaces.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: subinterstitial vein

hepatic portal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0010214
definition: Vein that starts in capillaries of the alimentary canal and ends in capillaries of the liver.
id: XAO:0000392
has_related_synonym: portal vein

Axiom
annotated target: Vein that starts in capillaries of the alimentary canal and ends in capillaries of the liver.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: hepatic portal vein

tail vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: tail vasculature
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0011105
definition: Vein in the tail returning blood from the tail to the heart.
id: XAO:0000393

Axiom
annotated target: Vein in the tail returning blood from the tail to the heart.
database_cross_reference: ZFA:0000180
annotated property: definition
annotated source: tail vein

pulmonary vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
database_cross_reference: AAO:0010521
definition: Any of the veins which collect blood from the lungs and some small vesicles received from the esophagus.
id: XAO:0000394

Axiom
database_cross_reference: AAO:0010521
annotated target: Any of the veins which collect blood from the lungs and some small vesicles received from the esophagus.
annotated property: definition
annotated source: pulmonary vein

medial abdominal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Vein in the posterior region that drains the ventral abdominal wall.
id: XAO:0000395

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Vein in the posterior region that drains the ventral abdominal wall.
annotated property: definition
annotated source: medial abdominal vein

head somite 1
type: Class
subclass of: head somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000042
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: Transient occipital somite that exists from NF stages 17 to 26 only.
id: XAO:0000396
has_related_synonym: somite W

Axiom
annotated target: Transient occipital somite that exists from NF stages 17 to 26 only.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head somite 1

Axiom
database_cross_reference: PMID:2769206
annotated target: somite W
annotated source: head somite 1
annotated property: has_related_synonym

sclerotome
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
database_cross_reference: AAO:0010571
definition: Somitic compartment that is a precursor of the axial skeleton.
id: XAO:0000397
has_related_synonym: sclerotomes

Axiom
annotated target: Somitic compartment that is a precursor of the axial skeleton.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: sclerotome

Axiom
annotated target: sclerotomes
annotated source: sclerotome
has_synonym_type: PLURAL
annotated property: has_related_synonym

tendon fibroblast
type: Class
subclass of: fibroblast
subclass of: Restriction
  on property: develops from
  some values from: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: death
definition: An elongated fibroblast type cell, the cytoplasm of which is stretched between the collagen fibres of the tendon.
id: XAO:0000399

Axiom
annotated target: An elongated fibroblast type cell, the cytoplasm of which is stretched between the collagen fibres of the tendon.
database_cross_reference: http://en.wikipedia.org/wiki/Tendon_cell
annotated property: definition
annotated source: tendon fibroblast

sclerotomal cartilage
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: part of
  some values from: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: sclerotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Sclerotome cells of the cartilage fate.
id: XAO:0000401

Axiom
annotated target: Sclerotome cells of the cartilage fate.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotomal cartilage

head somite 2
type: Class
subclass of: head somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: Transient occipital somite that exists from NF stages 18 to 29 only.
id: XAO:0000403
has_related_synonym: somite X

Axiom
database_cross_reference: PMID:2769206
annotated target: somite X
annotated source: head somite 2
annotated property: has_related_synonym

Axiom
annotated target: Transient occipital somite that exists from NF stages 18 to 29 only.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head somite 2

head somite 3
type: Class
subclass of: head somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: Transient occipital somite that exists from NF stages 18 to 29/30 only.
id: XAO:0000404
has_related_synonym: somite Y

Axiom
database_cross_reference: PMID:2769206
annotated target: somite Y
annotated source: head somite 3
annotated property: has_related_synonym

Axiom
annotated target: Transient occipital somite that exists from NF stages 18 to 29/30 only.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head somite 3

head somite 4
type: Class
subclass of: head somite
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
definition: Transient occipital somite that exists from NF stages 19 to late 30's.
id: XAO:0000405
has_related_synonym: somite Z

Axiom
database_cross_reference: PMID:2769206
annotated target: somite Z
annotated source: head somite 4
annotated property: has_related_synonym

Axiom
annotated target: Transient occipital somite that exists from NF stages 19 to late 30's.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: head somite 4

trunk somite 1
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Trunk somite that is initially the 5th somite, first forming around NF stage 19 and becoming more anteriorly positioned as the head somites degenerate. It is the most anterior somite by NF stage 45 and is adjacent to the otic vesicle.
id: XAO:0000406
has_related_synonym: fifth somite

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Trunk somite that is initially the 5th somite, first forming around NF stage 19 and becoming more anteriorly positioned as the head somites degenerate. It is the most anterior somite by NF stage 45 and is adjacent to the otic vesicle.
annotated property: definition
annotated source: trunk somite 1

trunk somite 2
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
definition: Trunk somite that is initially the sixth somite.
id: XAO:0000407

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Trunk somite that is initially the sixth somite.
annotated property: definition
annotated source: trunk somite 2

trunk somite 3
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: The 1st somite located posterior to the head.
id: XAO:0000408

Axiom
annotated target: The 1st somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 3

trunk somite 4
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: The 2nd somite located posterior to the head.
id: XAO:0000409

Axiom
annotated target: The 2nd somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 4

trunk somite 5
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: The 3rd somite located posterior to the head.
id: XAO:0000410

Axiom
annotated target: The 3rd somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 5

trunk somite 6
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: The 4th somite located posterior to the head.
id: XAO:0000411

Axiom
annotated target: The 4th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 6

trunk somite 7
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
definition: The 5th somite located posterior to the head.
id: XAO:0000412

Axiom
annotated target: The 5th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 7

sclerotomal mesenchyme
type: Class
subclass of: mesenchyme
subclass of: Restriction
  on property: develops from
  some values from: sclerotome
subclass of: Restriction
  on property: part of
  some values from: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Mesenchymal cells that break from the sclerotome. Such cells migrate from the somite to surround the notochord.
id: XAO:0000414

Axiom
database_cross_reference: ISBN:0123190606
annotated target: Mesenchymal cells that break from the sclerotome. Such cells migrate from the somite to surround the notochord.
annotated property: definition
annotated source: sclerotomal mesenchyme

notochordal sheath
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: part of
  some values from: notochord
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000074
subclass of: Restriction
  on property: develops from
  some values from: sclerotomal mesenchyme
definition: Mesenchymal covering surrounding the notochord, derived from sclerotomal mesenchyme.
id: XAO:0000415

Axiom
annotated target: Mesenchymal covering surrounding the notochord, derived from sclerotomal mesenchyme.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: notochordal sheath

trunk somite 8
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: The 6th somite located posterior to the head.
id: XAO:0000416

Axiom
annotated target: The 6th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 8

trunk somite 9
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
definition: The 7th somite located posterior to the head.
id: XAO:0000417

Axiom
annotated target: The 7th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 9

trunk somite 10
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
definition: The 8th somite located posterior to the head.
id: XAO:0000418

Axiom
annotated target: The 8th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 10

trunk somite 11
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
definition: The 9th somite located posterior to the head.
id: XAO:0000419

Axiom
annotated target: The 9th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 11

trunk somite 12
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
definition: The 10th somite located posterior to the head.
id: XAO:0000420

Axiom
annotated target: The 10th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 12

trunk somite 13
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: The 11th somite located posterior to the head.
id: XAO:0000421

Axiom
annotated target: The 11th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 13

trunk somite 14
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
definition: The 12th somite located posterior to the head.
id: XAO:0000422

Axiom
annotated target: The 12th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 14

trunk somite 15
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
definition: The 13th somite located posterior to the head.
id: XAO:0000423

Axiom
annotated target: The 13th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 15

trunk somite 16
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
definition: The 14th somite located posterior to the head. It forms at NF stage 28, by which time head somite 1 has degenerated.
id: XAO:0000424

Axiom
annotated target: The 14th somite located posterior to the head. It forms at NF stage 28, by which time head somite 1 has degenerated.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: trunk somite 16

trunk somite 17
type: Class
subclass of: trunk somite
subclass of: Restriction
  on property: develops from
  some values from: presomitic mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
definition: The 15th somite located posterior to the head.
id: XAO:0000425

Axiom
annotated target: The 15th somite located posterior to the head.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk somite 17

cranial nerve I
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: part of
  some values from: olfactory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: develops from
  some values from: olfactory placode
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Cranial nerve that supplies the nasal organ.
id: XAO:0000426
database_cross_reference: ZFA:0000249
has_related_synonym: olfactory nerve

Axiom
annotated target: Cranial nerve that supplies the nasal organ.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve I

gasserian ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: develops from
  some values from: trigeminal placode
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011045
definition: Sensory ganglion of the trigeminal nerve.
id: XAO:0000427
has_related_synonym: gasserian ganglia

Axiom
annotated target: gasserian ganglia
annotated source: gasserian ganglion
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Sensory ganglion of the trigeminal nerve.
database_cross_reference: http://en.wikipedia.org/wiki/Trigeminal_ganglion
annotated property: definition
annotated source: gasserian ganglion

trigeminal ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: trigeminal placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
definition: A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear.
database_cross_reference: AAO:0011107
id: XAO:0000428
has_related_synonym: trigeminal ganglia
has_related_synonym: trigeminus ganglion

Axiom
annotated target: A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear.
database_cross_reference: UBERON:0001675
annotated property: definition
annotated source: trigeminal ganglion

Axiom
annotated target: trigeminal ganglia
annotated source: trigeminal ganglion
has_synonym_type: PLURAL
annotated property: has_related_synonym

cranial nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: Any of the major paired nerves of the head or cephalic region. Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. They are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves.
database_cross_reference: UBERON:0001785
id: XAO:0000429
has_alternative_id: XAO:0003089
has_related_synonym: cephalic nerve
has_related_synonym: cranial nerves

Axiom
annotated target: Any of the major paired nerves of the head or cephalic region. Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. They are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cranial nerve

Rathke's pouch
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: develops from
  some values from: mouth primordium
subclass of: Restriction
  on property: part of
  some values from: mouth primordium
definition: A depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system.
database_cross_reference: AAO:0011094
id: XAO:0000430

Axiom
annotated target: A depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system.
database_cross_reference: UBERON:0005356
annotated property: definition
annotated source: Rathke's pouch

tooth
type: Class
subclass of: skeletal element
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: mouth primordium
subclass of: Restriction
  on property: part of
  some values from: cranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
definition: Each of a set of hard, bony enamel-coated structures in the jaws, used for biting.
id: XAO:0000431
has_broad_synonym: dentition
has_related_synonym: teeth

Axiom
database_cross_reference: AEO:0000220
annotated target: Each of a set of hard, bony enamel-coated structures in the jaws, used for biting.
annotated property: definition
annotated source: tooth

Axiom
annotated target: teeth
annotated source: tooth
has_synonym_type: PLURAL
annotated property: has_related_synonym

death
type: Class
subclass of: XAO_1000000
subclass of: Restriction
  on property: preceded by
  some values from: XAO_1000093
definition: The end of the animal's life.
id: XAO:0000437
has_obo_namespace: xenopus_developmental_stage

Axiom
annotated target: The end of the animal's life.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: death

filter chamber
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: part of
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000074
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
definition: The structure that enables tadpoles, which are suspension feeders, to trap food particles. The palatoquadrate, ceratohyal and the connecting muscles are responsible for the irrigation and ventilation of the filter apparatus.
id: XAO:0000439
has_related_synonym: coelom
has_related_synonym: coelomic filter chamber
has_exact_synonym: filter apparatus
has_exact_synonym: peribranchial chamber

Axiom
annotated target: The structure that enables tadpoles, which are suspension feeders, to trap food particles. The palatoquadrate, ceratohyal and the connecting muscles are responsible for the irrigation and ventilation of the filter apparatus.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: filter chamber

lateral line placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: lateral line system
definition: Thickened placodal areas located anterior and posterior to the otic vesicle. In Xenopus, there are 5 distinct lateral line placodes, each gives rise to a single lateral line nerve that will innervate lateral line hair cells and convey information on motion to the adjacent hindbrain.
id: XAO:0000440
has_broad_synonym: lateral line
has_related_synonym: lateral line placodes

Axiom
database_cross_reference: ISBN:0878933840
annotated target: Thickened placodal areas located anterior and posterior to the otic vesicle. In Xenopus, there are 5 distinct lateral line placodes, each gives rise to a single lateral line nerve that will innervate lateral line hair cells and convey information on motion to the adjacent hindbrain.
annotated property: definition
annotated source: lateral line placode

Axiom
annotated target: lateral line placodes
annotated source: lateral line placode
has_synonym_type: PLURAL
annotated property: has_related_synonym

infraorbital lateral line primordium
type: Class
subclass of: XAO_0004411
subclass of: Restriction
  on property: develops from
  some values from: lateral line placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000054
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Lateral line primordium which migrates ventrad along the posterior and ventral margin of the eye.
id: XAO:0000441

Axiom
annotated target: Lateral line primordium which migrates ventrad along the posterior and ventral margin of the eye.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: infraorbital lateral line primordium

supraorbital lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: develops from
  some values from: lateral line placode
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
database_cross_reference: AAO:0011103
definition: Lateral line situated along the dorsal margin of the eye.
id: XAO:0000442

Axiom
annotated target: Lateral line situated along the dorsal margin of the eye.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: supraorbital lateral line

trunk lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: develops from
  some values from: lateral line placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A lateral line that is present on the trunk of the organism.
id: XAO:0000443

Axiom
annotated target: A lateral line that is present on the trunk of the organism.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk lateral line

thyroid primordium
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000061
subclass of: Restriction
  on property: develops from
  some values from: pharyngeal cavity
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: endocrine system
database_cross_reference: AAO:0011106
definition: The initial thyroid precursor, which arises from the ventral aspect of the second pharyngeal pouch.
id: XAO:0000444
has_broad_synonym: thyroid

Axiom
annotated target: The initial thyroid precursor, which arises from the ventral aspect of the second pharyngeal pouch.
database_cross_reference: UBERON:0003091
annotated property: definition
annotated source: thyroid primordium

taste bud
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: gustatory system
subclass of: Restriction
  on property: develops from
  some values from: pharyngeal cavity
subclass of: Restriction
  on property: develops from
  some values from: tongue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000063
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010573
definition: The organ used for chemoreception.
id: XAO:0000445

Axiom
database_cross_reference: AAO:0010573
annotated target: The organ used for chemoreception.
annotated property: definition
annotated source: taste bud

tongue
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: develops from
  some values from: mandibular arch
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0010360
definition: The movable, muscular organ on the floor of the mouth.
id: XAO:0000446

Axiom
annotated target: The movable, muscular organ on the floor of the mouth.
database_cross_reference: UBERON:0001723
annotated property: definition
annotated source: tongue

branchial arch 1
type: Class
subclass of: branchial arch
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 3
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
database_cross_reference: AAO:0010365
definition: The most anterior, or first, pharygeal/branchial arch, composed of the mandibular process, forming the posterior border of the stomodeum, and the maxillary process anterior to the stomodeum, contains the first aortic arch.
id: XAO:0000447
has_exact_synonym: first branchial arch
has_related_synonym: third visceral arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The most anterior, or first, pharygeal/branchial arch, composed of the mandibular process, forming the posterior border of the stomodeum, and the maxillary process anterior to the stomodeum, contains the first aortic arch.
annotated property: definition
annotated source: branchial arch 1

gill primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: develops from
  some values from: branchial arch 2
subclass of: Restriction
  on property: part of
  some values from: respiratory system
subclass of: Restriction
  on property: develops from
  some values from: branchial arch 1
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
definition: A swelling from the 3rd visceral arch at NF stage 35&36, which co-occurs with a depression between the 3rd and 6th, forming the external gills by NF stage 39.
id: XAO:0000448
has_related_synonym: external gill anlage
has_broad_synonym: gill

Axiom
annotated target: A swelling from the 3rd visceral arch at NF stage 35&36, which co-occurs with a depression between the 3rd and 6th, forming the external gills by NF stage 39.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: gill primordium

branchial arch 2
type: Class
subclass of: branchial arch
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 4
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
database_cross_reference: AAO:0010366
definition: The second pharyngeal/branchial arch; arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature.
id: XAO:0000449
has_related_synonym: fourth visceral arch
has_exact_synonym: second branchial arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The second pharyngeal/branchial arch; arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature.
annotated property: definition
annotated source: branchial arch 2

branchial arch 3
type: Class
subclass of: branchial arch
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 5
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010367
definition: The third in a series of paired bars in the wall of the pharynx, within which are formed the third aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.
id: XAO:0000451
has_related_synonym: fifth visceral arch
has_exact_synonym: third branchial arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The third in a series of paired bars in the wall of the pharynx, within which are formed the third aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.
annotated property: definition
annotated source: branchial arch 3

ultimobranchial body
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: endocrine system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: branchial arch 4
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010547
definition: Anatomical structure which includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch.
id: XAO:0000452

Axiom
database_cross_reference: AAO:0010547
annotated target: Anatomical structure which includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch.
annotated property: definition
annotated source: ultimobranchial body

branchial arch 4
type: Class
subclass of: branchial arch
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: develops from
  some values from: visceral pouch 6
database_cross_reference: AAO:0010368
definition: The forth in a series of paired bars in the wall of the pharynx, within which are formed the forth aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.
id: XAO:0000453
has_exact_synonym: fourth branchial arch
has_related_synonym: sixth visceral arch

Axiom
database_cross_reference: ISBN:0-02-377110-0
annotated target: The forth in a series of paired bars in the wall of the pharynx, within which are formed the forth aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.
annotated property: definition
annotated source: branchial arch 4

liver parenchyme
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: develops from
  some values from: liver diverticulum
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: liver
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
database_cross_reference: AAO:0010405
definition: The functional units of the liver including the lobules.
id: XAO:0000454

Axiom
annotated target: The functional units of the liver including the lobules.
database_cross_reference: UBERON:0001280
annotated property: definition
annotated source: liver parenchyme

biliary tree
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: liver and biliary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: liver diverticulum
database_cross_reference: AAO:0011020
definition: Hollow tree organ, the organ parts of which consist of the bile ducts.
id: XAO:0000455
has_related_synonym: biliary tract

Axiom
annotated target: Hollow tree organ, the organ parts of which consist of the bile ducts.
database_cross_reference: UBERON:0001173
annotated property: definition
annotated source: biliary tree

pyloric sphincter
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: stomach
database_cross_reference: AAO:0011093
definition: Sphincter muscle that is part of the pyloric region of the stomach.
id: XAO:0000457

Axiom
annotated target: Sphincter muscle that is part of the pyloric region of the stomach.
database_cross_reference: UBERON:0001202
annotated property: definition
annotated source: pyloric sphincter

occipital lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: lateral line placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
definition: A short lateral line that extends from the ear in a posterior-dorsal direction.
database_cross_reference: AAO:0011075
id: XAO:0000458

Axiom
annotated target: A short lateral line that extends from the ear in a posterior-dorsal direction.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: occipital lateral line

infraorbital lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: develops from
  some values from: infraorbital lateral line primordium
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011053
definition: Lateral line situated along the posterior and ventral margin of the eye.
id: XAO:0000459

Axiom
annotated target: Lateral line situated along the posterior and ventral margin of the eye.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: infraorbital lateral line

hyomandibular lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
subclass of: Restriction
  on property: develops from
  some values from: infraorbital lateral line primordium
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Lateral line complex that radiates on the ventral side of the head from a point between the eye and the base of the larval tentacle.
id: XAO:0000460

Axiom
annotated target: Lateral line complex that radiates on the ventral side of the head from a point between the eye and the base of the larval tentacle.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: hyomandibular lateral line

trunk placode
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: Thickened plate of ectoderm that contributes to the formation of the dorsal, middle, or ventral lateral line.
id: XAO:0000461

Axiom
annotated target: Thickened plate of ectoderm that contributes to the formation of the dorsal, middle, or ventral lateral line.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk placode

dorsal lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: trunk placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
database_cross_reference: AAO:0011030
definition: The dorsal most of the sensory system on the surface of the tadpole consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the tadpole through the water, as well as facilitating schooling, prey capture, and predator and obstacle avoidance.
id: XAO:0000462

Axiom
annotated target: The dorsal most of the sensory system on the surface of the tadpole consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the tadpole through the water, as well as facilitating schooling, prey capture, and predator and obstacle avoidance.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: dorsal lateral line

middle lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: trunk placode
definition: A lateral line that extends from the ear in a posterior direction between the upper and lower lateral lines.
id: XAO:0000463
database_cross_reference: ZFA:0000344

Axiom
annotated target: A lateral line that extends from the ear in a posterior direction between the upper and lower lateral lines.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: middle lateral line

ventral lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: develops from
  some values from: trunk placode
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Ventrally located lateral line that runs over the abdomen.
id: XAO:0000464

Axiom
annotated target: Ventrally located lateral line that runs over the abdomen.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ventral lateral line

caudal lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: develops from
  some values from: ventral lateral line
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000056
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011024
definition: Cranial nerve of the caudal lateral line enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines.
id: XAO:0000465

Axiom
annotated target: Cranial nerve of the caudal lateral line enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: caudal lateral line

dorsal pancreatic bud
type: Class
subclass of: primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: develops from
  some values from: midgut
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: develops from
  some values from: hepato-pancreatic progenitor cell
database_cross_reference: AAO:0011031
definition: The pancreatic bud that gives rise to the accessory pancreatic duct.
id: XAO:0000467
has_broad_synonym: pancreas
has_exact_synonym: primary pancreatic bud

Axiom
annotated target: The pancreatic bud that gives rise to the accessory pancreatic duct.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: dorsal pancreatic bud

dorsal tail fin
type: Class
subclass of: fin
subclass of: Restriction
  on property: develops from
  some values from: trunk neural crest
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
database_cross_reference: AAO:0010203
definition: The dorsal part of the tail fin.
id: XAO:0000469

Axiom
annotated target: The dorsal part of the tail fin.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: dorsal tail fin

unicellular gland
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: develops from
  some values from: sensorial layer
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000010
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000062
database_cross_reference: AAO:0010377
definition: Any of the large number of glands of the larval skin, particularly common in the fins and adjacent skin of the trunk; also formed in the former frontal gland area on the upper jaw.
id: XAO:0000470

Axiom
annotated target: Any of the large number of glands of the larval skin, particularly common in the fins and adjacent skin of the trunk; also formed in the former frontal gland area on the upper jaw.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: unicellular gland

xanthophore
type: Class
subclass of: pigment cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A type of colored melanophore (mobile pigment cells of the dermis and epidermis) that contain fat-soluble carotenoids (obtained from the diet) and pteridines (synthesised from the cell) which are stored in pterinosomes. Their color depends on the pattern of carotenoids and pteridines. Xanthophores are rarely found in pre-metamorphic larvae.
database_cross_reference: CL:0000430
id: XAO:0000471

Axiom
annotated target: A type of colored melanophore (mobile pigment cells of the dermis and epidermis) that contain fat-soluble carotenoids (obtained from the diet) and pteridines (synthesised from the cell) which are stored in pterinosomes. Their color depends on the pattern of carotenoids and pteridines. Xanthophores are rarely found in pre-metamorphic larvae.
database_cross_reference: CL:0000430
database_cross_reference: ISBN:0-226-55763-4
annotated property: definition
annotated source: xanthophore

iridophore
type: Class
subclass of: pigment cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000071
definition: A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color.
database_cross_reference: CL:0000431
id: XAO:0000472
has_related_synonym: guanophore

Axiom
annotated target: A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color.
database_cross_reference: AAO:0010318
annotated property: definition
annotated source: iridophore

choroid fissure
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: develops from
  some values from: optic vesicle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
definition: A break in the continuity of the optic cup where the two sides of the cup meet.
database_cross_reference: AAO:0011026
id: XAO:0000474
has_related_synonym: optic fissure
has_related_synonym: ventral choroidal fissure

Axiom
annotated target: A break in the continuity of the optic cup where the two sides of the cup meet.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: choroid fissure

optic stalk
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: diencephalon
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: optic vesicle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0011077
definition: Neural tissue comprising the proximal part of either of the optic vesicles as they project towards the sides of the head; it remains narrow and constitutes the optic stalk (the peripheral part of each expands to form a hollow bulb).
id: XAO:0000475

Axiom
annotated target: Neural tissue comprising the proximal part of either of the optic vesicles as they project towards the sides of the head; it remains narrow and constitutes the optic stalk (the peripheral part of each expands to form a hollow bulb).
database_cross_reference: UBERON:0003098
database_cross_reference: XAO:curator
annotated property: definition
annotated source: optic stalk

cranial neural crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: neural crest
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
database_cross_reference: AAO:0010580
has_exact_synonym: CNC
definition: The most anterior of 5 distinct and partially overlapping functional domains of the premigratory neural crest, which are intially part of the neural epithelium. CNC cells migrate through the extracelluar matrix in 4 highly conserved streams: the mandibular crest, hyoid crest, anterior branchial crest and the posterior branchial crest.
id: XAO:0001001
has_related_synonym: cephalic neural crest
has_related_synonym: head crest

Axiom
annotated target: The most anterior of 5 distinct and partially overlapping functional domains of the premigratory neural crest, which are intially part of the neural epithelium. CNC cells migrate through the extracelluar matrix in 4 highly conserved streams: the mandibular crest, hyoid crest, anterior branchial crest and the posterior branchial crest.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cranial neural crest

lung primordium
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: respiratory system
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000065
definition: A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum.
database_cross_reference: AAO:0011059
id: XAO:0001002
has_related_synonym: lateral diverticula
has_broad_synonym: lung

Axiom
annotated target: A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: lung primordium

circulatory system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000959
definition: Anatomical system that has as its parts the blood and lymph vessels.
id: XAO:0001010
has_exact_synonym: vascular system

Axiom
annotated target: Anatomical system that has as its parts the blood and lymph vessels.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: circulatory system

blood vessel
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: circulatory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011004
definition: Any of the vessels through which blood circulates in the body.
id: XAO:0001011
has_related_synonym: blood vessels
has_related_synonym: vasculature

Axiom
annotated target: blood vessels
annotated source: blood vessel
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Any of the vessels through which blood circulates in the body.
database_cross_reference: BTO:0001102
annotated property: definition
annotated source: blood vessel

Stirnorgan
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: develops from
  some values from: pineal gland
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Structure that is part of the pineal system, is located in the skin on the dorsal surface of the head, and is exposed continuously to ambient illumination.
id: XAO:0001012
has_related_synonym: frontal organ

Axiom
annotated target: Structure that is part of the pineal system, is located in the skin on the dorsal surface of the head, and is exposed continuously to ambient illumination.
database_cross_reference: http://dx.doi.org/10.1007/BF00663609
annotated property: definition
annotated source: Stirnorgan

musculature of face
type: Class
subclass of: muscle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: head
definition: The facial muscles are a group of striated muscles innervated by the facial nerves.
database_cross_reference: UBERON:0004473
id: XAO:0001013
has_exact_synonym: facial muscle
has_exact_synonym: facial muscles

Axiom
annotated target: facial muscles
annotated source: musculature of face
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: The facial muscles are a group of striated muscles innervated by the facial nerves.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: musculature of face

melanophore
type: Class
subclass of: pigment cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: A pigment cell that contains melanin, a brownish-black pigment.
database_cross_reference: CL:0000148
id: XAO:0001014
has_related_synonym: melanocyte

Axiom
annotated target: A pigment cell that contains melanin, a brownish-black pigment.
database_cross_reference: NLM:melanophore
annotated property: definition
annotated source: melanophore

rectal diverticulum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: cloaca
subclass of: Restriction
  on property: part of
  some values from: pronephric kidney
definition: An outgrowth of the cloaca that links the pronephric kidney to the exterior.
database_cross_reference: UBERON:0006172
id: XAO:0001015
has_related_synonym: rectal diverticula

Axiom
annotated target: An outgrowth of the cloaca that links the pronephric kidney to the exterior.
database_cross_reference: UBERON:0006172
annotated property: definition
annotated source: rectal diverticulum

Axiom
annotated target: rectal diverticula
annotated source: rectal diverticulum
has_synonym_type: PLURAL
annotated property: has_related_synonym

abdominal myoblast
type: Class
subclass of: myoblast
subclass of: Restriction
  on property: part of
  some values from: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0010314
definition: The myoblast that forms the muscles of the anterior abdominal walls.
id: XAO:0001016
has_related_synonym: abdominal musculature

Axiom
database_cross_reference: AAO:0010314
annotated target: The myoblast that forms the muscles of the anterior abdominal walls.
annotated property: definition
annotated source: abdominal myoblast

connective tissue
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
definition: Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.
database_cross_reference: VSAO:0000017
id: XAO:0001017
has_exact_synonym: portion of connective tissue

Axiom
annotated target: Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.
database_cross_reference: ZFA:0001632
annotated property: definition
annotated source: connective tissue

anterior lymph sac
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000071
subclass of: Restriction
  on property: develops from
  some values from: venous endothelium
subclass of: Restriction
  on property: part of
  some values from: lymphatic system
definition: The protrusion of mesenchymal tissue of the anterior cardinal vein which form lymph sacs.
id: XAO:0001018
has_related_synonym: rostral lymph sac

Axiom
database_cross_reference: PMID:17062017
annotated target: The protrusion of mesenchymal tissue of the anterior cardinal vein which form lymph sacs.
annotated property: definition
annotated source: anterior lymph sac

proctodeum
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0011087
definition: Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage. The most posterior section of the gut.
id: XAO:0001019
has_related_synonym: anus
has_related_synonym: anus porus
has_exact_synonym: proctodaeum
has_related_synonym: vent

Axiom
annotated target: Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage. The most posterior section of the gut.
database_cross_reference: ZFA:0000066
annotated property: definition
annotated source: proctodeum

elastica externa
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: develops from
  some values from: notochord
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000074
definition: Notochordal membrane covering derived from notochordal epithelium. Its first indication is at NF stage 24, and it is a distinct membrane by NF stage 28.
id: XAO:0001020
has_related_synonym: notochordal sheath

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Notochordal membrane covering derived from notochordal epithelium. Its first indication is at NF stage 24, and it is a distinct membrane by NF stage 28.
annotated property: definition
annotated source: elastica externa

notochordal epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: develops from
  some values from: notochord
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000074
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
definition: Outer layer of cells of the differentiating notochord, which give rise to the elastica externa and interna.
id: XAO:0001021

Axiom
annotated target: Outer layer of cells of the differentiating notochord, which give rise to the elastica externa and interna.
database_cross_reference: http://dev.biologists.org/content/1/4/411.abstract
annotated property: definition
annotated source: notochordal epithelium

first pancreatic bud
type: Class
subclass of: primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: part of
  some values from: alimentary system
database_cross_reference: AAO:0011040
definition: One of two pancreatic primordia that give rise to a ventral pancreatic bud.
id: XAO:0001101
has_broad_synonym: pancreas

Axiom
annotated target: One of two pancreatic primordia that give rise to a ventral pancreatic bud.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: first pancreatic bud

second pancreatic bud
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: develops from
  some values from: foregut
subclass of: Restriction
  on property: part of
  some values from: alimentary system
definition: Second of two pancreatic primordia that give rise to a ventral pancreatic bud.
id: XAO:0001102
has_broad_synonym: pancreas

Axiom
annotated target: Second of two pancreatic primordia that give rise to a ventral pancreatic bud.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: second pancreatic bud

ventral pancreatic bud
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
subclass of: Restriction
  on property: develops from
  some values from: first pancreatic bud
subclass of: Restriction
  on property: develops from
  some values from: hepato-pancreatic progenitor cell
subclass of: Restriction
  on property: develops from
  some values from: second pancreatic bud
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000057
database_cross_reference: AAO:0011111
definition: Either of the two ventral pancreas rudiments that join and fuse with the right end of the dorsal pancreatic rudiment.
id: XAO:0001103
has_broad_synonym: pancreas

Axiom
annotated target: Either of the two ventral pancreas rudiments that join and fuse with the right end of the dorsal pancreatic rudiment.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: ventral pancreatic bud

pronephric kidney
type: Class
subclass of: multi-tissue structure
subclass of: kidney
subclass of: Restriction
  on property: develops from
  some values from: pronephric mesenchyme
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
database_cross_reference: AAO:0011089
definition: Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.
id: XAO:0002000
has_related_synonym: pronephros
in_subset: frequent anatomy items

Axiom
annotated target: Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: pronephric kidney

anatomical structure
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: CARO:0000003
definition: Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome.
id: XAO:0003000

Axiom
database_cross_reference: CARO:0000003
annotated target: Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome.
annotated property: definition
annotated source: anatomical structure

anatomical group
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: develops from
  some values from: embryo
definition: Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue.
database_cross_reference: CARO:0000054
id: XAO:0003001

Axiom
annotated target: Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue.
database_cross_reference: CARO:0000054
annotated property: definition
annotated source: anatomical group

anatomical system
type: Class
subclass of: anatomical group
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical group that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.
database_cross_reference: CARO:0000011
id: XAO:0003002

Axiom
annotated target: Anatomical group that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.
database_cross_reference: CARO:0000011
annotated property: definition
annotated source: anatomical system

unspecified
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
comment: Annotation of data with this anatomy term indicates that a structure or tissue was not specified by the investigator.
id: XAO:0003003

whole organism
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical structure that is an individual member of Xenopus laevis.
database_cross_reference: CARO:0000012
id: XAO:0003004
has_broad_synonym: ubiquitous
in_subset: organism views
in_subset: sectional anatomy items

Axiom
annotated target: Anatomical structure that is an individual member of Xenopus laevis.
database_cross_reference: CARO:0000012
annotated property: definition
annotated source: whole organism

female organism
type: Class
subclass of: whole organism
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: CARO:0000028
definition: Gonochoristic organism that can produce female gametes.
id: XAO:0003005

Axiom
database_cross_reference: CARO:0000028
annotated target: Gonochoristic organism that can produce female gametes.
annotated property: definition
annotated source: female organism

male organism
type: Class
subclass of: whole organism
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: CARO:0000027
definition: Gonochoristic organism that can produce male gametes.
id: XAO:0003006

Axiom
database_cross_reference: CARO:0000027
annotated target: Gonochoristic organism that can produce male gametes.
annotated property: definition
annotated source: male organism

anatomical entity in vitro
type: Class
subclass of: Xenopus anatomical entity
definition: An experimentally manipulated tissue, or portion of the developing embryo, that can be culture alone, in vitro.
id: XAO:0003007
has_obo_namespace: xenopus_anatomy_in_vitro

Axiom
annotated target: An experimentally manipulated tissue, or portion of the developing embryo, that can be culture alone, in vitro.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: anatomical entity in vitro

activin-induced ectoderm
type: Class
subclass of: anatomical entity in vitro
definition: Ectoderm section that has been dissected from the embryo, and treated with activin, and maintained in vitro.
id: XAO:0003008
has_obo_namespace: xenopus_anatomy_in_vitro

Axiom
annotated target: Ectoderm section that has been dissected from the embryo, and treated with activin, and maintained in vitro.
database_cross_reference: PMID:14061885
annotated property: definition
annotated source: activin-induced ectoderm

disaggregated/reaggregated ectoderm treated with activin
type: Class
subclass of: anatomical entity in vitro
definition: At stage 8 ectoderm of Xenopus laevis embryos were cut and disaggregated. The cells were treated with activin at a concentration to induce endodermal tissue. Afterwards the reaggregated cells were cultured until control sibling embryos reaching stage 12/13.
id: XAO:0003009
has_obo_namespace: xenopus_anatomy_in_vitro

Axiom
annotated target: At stage 8 ectoderm of Xenopus laevis embryos were cut and disaggregated. The cells were treated with activin at a concentration to induce endodermal tissue. Afterwards the reaggregated cells were cultured until control sibling embryos reaching stage 12/13.
database_cross_reference: http://www.ncbi.nlm.nih.gov/UniGene/library.cgi
annotated property: definition
annotated source: disaggregated/reaggregated ectoderm treated with activin

aorta
type: Class
subclass of: artery
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
database_cross_reference: AAO:0010213
definition: The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs.
id: XAO:0003010

Axiom
database_cross_reference: AAO:0010213
annotated target: The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs.
annotated property: definition
annotated source: aorta

primary germ layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: embryo
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
definition: A layer of cells produced during the process of gastrulation during the early development of the embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The types of germ layers are the endoderm, ectoderm, and mesoderm.
database_cross_reference: AAO:0000480
id: XAO:0003011
has_related_synonym: embryonic germ layer
has_related_synonym: germ layer

Axiom
annotated target: A layer of cells produced during the process of gastrulation during the early development of the embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The types of germ layers are the endoderm, ectoderm, and mesoderm.
database_cross_reference: BTO:0000556
annotated property: definition
annotated source: primary germ layer

cell
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:0000013
id: XAO:0003012

Axiom
annotated target: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: GO:0005623
annotated property: definition
annotated source: cell

organism subdivision
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
definition: Anatomical structure that is a primary subdivision of the whole organism.
database_cross_reference: CARO:0000032
id: XAO:0003013
has_related_synonym: body part

Axiom
annotated target: Anatomical structure that is a primary subdivision of the whole organism.
database_cross_reference: CARO:0000032
annotated property: definition
annotated source: organism subdivision

pigment cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: trunk neural crest
subclass of: Restriction
  on property: part of
  some values from: skin
database_cross_reference: CL:0000147
definition: Cell type that contains a deposition of coloring matter, the first of which differentiate during late tailbud stage, and that by NF stage 56 has produced a fully differentiated larval pigmentation pattern.
id: XAO:0003014
has_related_synonym: chromatophore

Axiom
annotated target: Cell type that contains a deposition of coloring matter, the first of which differentiate during late tailbud stage, and that by NF stage 56 has produced a fully differentiated larval pigmentation pattern.
database_cross_reference: ISBN:0815318960
database_cross_reference: NLM:pigment+cell
annotated property: definition
annotated source: pigment cell

myoblast
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
database_cross_reference: CL:0000056
definition: Embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm.
id: XAO:0003015

Axiom
database_cross_reference: CL:0000056
annotated target: Embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm.
annotated property: definition
annotated source: myoblast

blastomere
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: embryo
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000019
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000011
database_cross_reference: CL:0000353
definition: Undifferentiated cell that is produced by early cleavages of the fertilized egg (zygote).
id: XAO:0003016

Axiom
database_cross_reference: CL:0000353
annotated target: Undifferentiated cell that is produced by early cleavages of the fertilized egg (zygote).
annotated property: definition
annotated source: blastomere

fibroblast
type: Class
subclass of: mesodermal cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: A connective tissue cell that secretes an extracellular matrix rich in collagen and other macromolecules.
database_cross_reference: CL:0000057
id: XAO:0003017

Axiom
annotated target: A connective tissue cell that secretes an extracellular matrix rich in collagen and other macromolecules.
database_cross_reference: CL:0000057
annotated property: definition
annotated source: fibroblast

primary spermatogonium
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000071
subclass of: Restriction
  on property: part of
  some values from: testis
subclass of: Restriction
  on property: develops from
  some values from: primordial germ cell
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A germ cell that is a primordial spermatocyte in a male and that develops into secondary spermatogonia by mitotic division.
database_cross_reference: AAO:0010298
id: XAO:0003018
has_related_synonym: primary spermatogonia

Axiom
annotated target: A germ cell that is a primordial spermatocyte in a male and that develops into secondary spermatogonia by mitotic division.
database_cross_reference: ISSN:0289-0003
annotated property: definition
annotated source: primary spermatogonium

Axiom
annotated target: primary spermatogonia
annotated source: primary spermatogonium
has_synonym_type: PLURAL
annotated property: has_related_synonym

spermatocyte
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000071
subclass of: Restriction
  on property: develops from
  some values from: secondary spermatogonium
database_cross_reference: CL:0000017
definition: The developing male gamete.
id: XAO:0003019

Axiom
annotated target: The developing male gamete.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: spermatocyte

secondary spermatogonium
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000071
subclass of: Restriction
  on property: develops from
  some values from: primary spermatogonium
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A type of germ cell that results from the mitotic division of a primary spermatogonium.
database_cross_reference: AAO:0010300
id: XAO:0003020
has_related_synonym: secondary spermatogonia

Axiom
annotated target: A type of germ cell that results from the mitotic division of a primary spermatogonium.
database_cross_reference: ISSN:0289-0003
annotated property: definition
annotated source: secondary spermatogonium

Axiom
annotated target: secondary spermatogonia
annotated source: secondary spermatogonium
has_synonym_type: PLURAL
annotated property: has_related_synonym

spinal cord neuron
type: Class
id: XAO:0003021
deprecated: true

Rohon-Beard neuron
type: Class
subclass of: neuron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: neural plate
database_cross_reference: CL:0000247
has_related_synonym: Rohon Beard cell
definition: Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. It first appears in trunk levels at NF stage 33/34, and at NF stage 35/36 has somas that are the largest in the spinal cord. It forms a nearly continuous double row of cells along the cord's medial dorsal surface and contributes ascending and descending axons to the dorsal tract. It appears well back in the tail by NF stage 39, begins to decline at NF stage 50 and is few in number, with pycnotic nuclei, at NF stage 55.
id: XAO:0003022

Axiom
database_cross_reference: ISBN:0815318960
database_cross_reference: PMID:17506218
annotated target: Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. It first appears in trunk levels at NF stage 33/34, and at NF stage 35/36 has somas that are the largest in the spinal cord. It forms a nearly continuous double row of cells along the cord's medial dorsal surface and contributes ascending and descending axons to the dorsal tract. It appears well back in the tail by NF stage 39, begins to decline at NF stage 50 and is few in number, with pycnotic nuclei, at NF stage 55.
annotated property: definition
annotated source: Rohon-Beard neuron

neuron
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: migrating neuroblast
subclass of: Restriction
  on property: part of
  some values from: nervous system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
database_cross_reference: CL:0000540
definition: Cell that is the basic unit of nervous tissue, each consisting of a body, an axon, and dendrites, and the purpose of which is to receive, conduct, and transmit impulses in the nervous system.
id: XAO:0003023
has_related_synonym: nerve cell

Axiom
database_cross_reference: CL:0000540
annotated target: Cell that is the basic unit of nervous tissue, each consisting of a body, an axon, and dendrites, and the purpose of which is to receive, conduct, and transmit impulses in the nervous system.
annotated property: definition
annotated source: neuron

head
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: part of
  some values from: head region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010335
definition: Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions.
id: XAO:0003024
in_subset: frequent anatomy items
in_subset: organism views

Axiom
database_cross_reference: AAO:0010335
annotated target: Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions.
annotated property: definition
annotated source: head

trunk
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: part of
  some values from: trunk region
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010339
definition: Organism subdivision that is the part of the body posterior to the head and anterior to the tail.
id: XAO:0003025
in_subset: organism views

Axiom
annotated target: Organism subdivision that is the part of the body posterior to the head and anterior to the tail.
database_cross_reference: ZFA:0001115
annotated property: definition
annotated source: trunk

tail
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: part of
  some values from: tail region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
database_cross_reference: AAO:0010338
definition: Organism subdivision that is the terminal, flexible posterior appendage of the larva. It is resorbed during metamorphosis beginning with degeneration of the notochord's distal tip at NF stage 61, followed by degeneration gradually extending to its more proximal regions and reaching its proximal end by NF stage 62. By NF stage 66 it exists only as a small dorsal swelling.
id: XAO:0003026
in_subset: organism views

Axiom
database_cross_reference: ISBN:0471209627
database_cross_reference: OMD:tail
annotated target: Organism subdivision that is the terminal, flexible posterior appendage of the larva. It is resorbed during metamorphosis beginning with degeneration of the notochord's distal tip at NF stage 61, followed by degeneration gradually extending to its more proximal regions and reaching its proximal end by NF stage 62. By NF stage 66 it exists only as a small dorsal swelling.
annotated property: definition
annotated source: tail

limb
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
database_cross_reference: AAO:0010336
definition: Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation.
id: XAO:0003027

Axiom
annotated target: Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: limb

surface structure
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010337
definition: Organism subdivision that is the collection of anatomical structures on the body surface.
id: XAO:0003028

Axiom
annotated target: Organism subdivision that is the collection of anatomical structures on the body surface.
database_cross_reference: ZFA:0000292
annotated property: definition
annotated source: surface structure

mouth
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: head
database_cross_reference: AAO:0010355
definition: Cavity in which food is initially ingested and generally contains teeth, tongue and glands.
id: XAO:0003029

Axiom
database_cross_reference: AAO:0010355
annotated target: Cavity in which food is initially ingested and generally contains teeth, tongue and glands.
annotated property: definition
annotated source: mouth

forelimb
type: Class
subclass of: limb
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004284
subclass of: Restriction
  on property: develops from
  some values from: forelimb bud
database_cross_reference: AAO:0000205
definition: One of the pair of limbs that are situated anteriorly, develop in sacs that separate them from the gill chamber, are well-defined buds by NF stage 48, are innervated by NF stage 51, and are ossified by NF stage 59.
id: XAO:0003030
has_exact_synonym: anterior limb
has_exact_synonym: fore limb

Axiom
database_cross_reference: BTO:0001729
database_cross_reference: ISBN:0471209627
annotated target: One of the pair of limbs that are situated anteriorly, develop in sacs that separate them from the gill chamber, are well-defined buds by NF stage 48, are innervated by NF stage 51, and are ossified by NF stage 59.
annotated property: definition
annotated source: forelimb

hindlimb
type: Class
subclass of: limb
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: XAO_0004285
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: hindlimb bud
database_cross_reference: AAO:0000219
definition: One of the pair of limbs that are situated posteriorly, are evident as buds laterally by NF stage 47, and are innervated by NF stage 51.
id: XAO:0003031
has_exact_synonym: hind limb
has_exact_synonym: posterior limb

Axiom
database_cross_reference: ISBN:0471209627
annotated target: One of the pair of limbs that are situated posteriorly, are evident as buds laterally by NF stage 47, and are innervated by NF stage 51.
annotated property: definition
annotated source: hindlimb

digit
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: autopod
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
definition: One of several most distal parts of a limb.
database_cross_reference: UBERON:0002544
id: XAO:0003032

Axiom
annotated target: One of several most distal parts of a limb.
database_cross_reference: UBERON:0002544
annotated property: definition
annotated source: digit

nostril
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000070
subclass of: Restriction
  on property: part of
  some values from: head
database_cross_reference: AAO:0010358
definition: Surface structure that provides one of the small external openings of the head that give passage to air for breathing.
id: XAO:0003033

Axiom
database_cross_reference: OMD:nostril
annotated target: Surface structure that provides one of the small external openings of the head that give passage to air for breathing.
annotated property: definition
annotated source: nostril

viscus
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: trunk
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
definition: An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper.
database_cross_reference: BTO:0001491
id: XAO:0003034
has_related_synonym: viscera

Axiom
annotated target: An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper.
database_cross_reference: BTO:0001491
annotated property: definition
annotated source: viscus

Axiom
annotated target: viscera
annotated source: viscus
has_synonym_type: PLURAL
annotated property: has_related_synonym

hind digit
type: Class
subclass of: digit
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: hindlimb skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: XAO_0004300
definition: A digit that is one of several most distal parts of a hind limb.
database_cross_reference: AAO:0000888
id: XAO:0003035
has_exact_synonym: toe

Axiom
annotated target: A digit that is one of several most distal parts of a hind limb.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hind digit

fore digit
type: Class
subclass of: digit
subclass of: Restriction
  on property: part of
  some values from: forelimb skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000068
subclass of: Restriction
  on property: part of
  some values from: XAO_0004299
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A digit that is one of several most distal parts of a forelimb.
database_cross_reference: AAO:0000857
id: XAO:0003036

Axiom
annotated target: A digit that is one of several most distal parts of a forelimb.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: fore digit

multi-tissue structure
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: develops from
  some values from: embryo
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.
database_cross_reference: CARO:0000055
id: XAO:0003037

Axiom
annotated target: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.
database_cross_reference: CARO:0000055
annotated property: definition
annotated source: multi-tissue structure

simple organ
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: CARO:0000021
definition: Multi-tissue structure that is not part of a compound organ.
id: XAO:0003038

Axiom
database_cross_reference: CARO:0000021
annotated target: Multi-tissue structure that is not part of a compound organ.
annotated property: definition
annotated source: simple organ

compound organ component
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: compound organ
database_cross_reference: CARO:0000019
definition: Multi-tissue structure that is part of a compound organ.
id: XAO:0003039

Axiom
database_cross_reference: CARO:0000019
annotated target: Multi-tissue structure that is part of a compound organ.
annotated property: definition
annotated source: compound organ component

portion of tissue
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: embryo
definition: Anatomical structure that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: CARO:0000043
id: XAO:0003040

Axiom
annotated target: Anatomical structure that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: CARO:0000043
annotated property: definition
annotated source: portion of tissue

compound organ
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: develops from
  some values from: embryo
definition: Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types.
database_cross_reference: CARO:0000024
id: XAO:0003041

Axiom
annotated target: Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types.
database_cross_reference: CARO:0000024
annotated property: definition
annotated source: compound organ

embryonic structure
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: develops from
  some values from: embryo
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: embryo
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
database_cross_reference: AAO:0000138
definition: An anatomical structure that exists only before the organism is fully formed.
id: XAO:0003042

Axiom
annotated target: An anatomical structure that exists only before the organism is fully formed.
database_cross_reference: BTO:0000174
annotated property: definition
annotated source: embryonic structure

primordium
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
definition: An embryonic structure that is the rudiment or commencement of a part or organ.
database_cross_reference: UBERON:0001048
id: XAO:0003043
has_related_synonym: primordia

Axiom
annotated target: primordia
annotated source: primordium
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: An embryonic structure that is the rudiment or commencement of a part or organ.
database_cross_reference: UBERON:0001048
annotated property: definition
annotated source: primordium

endomesoderm
type: Class
subclass of: primary germ layer
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
database_cross_reference: AAO:0010619
definition: Primary germ layer that can give rise to both mesoderm and endoderm.
id: XAO:0003044
has_related_synonym: mesendoderm

Axiom
annotated target: Primary germ layer that can give rise to both mesoderm and endoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: endomesoderm

epithelium
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: CARO:0000066
definition: Portion of tissue that consists of one or more layers of epithelial cells connected to each other by cell junctions and that is underlain by a basal lamina.
id: XAO:0003045

Axiom
database_cross_reference: CARO:0000066
annotated target: Portion of tissue that consists of one or more layers of epithelial cells connected to each other by cell junctions and that is underlain by a basal lamina.
annotated property: definition
annotated source: epithelium

mesenchyme
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010427
definition: Portion of embryonic tissue consisting of loosely organized, undifferentiated mesodermal or neural crest derived cells, that have specific properties (they are migratory, have no polarity). Mesenchyme cells are incorporated into a wide variety of structures including connective tissue, blood, bone and cartilage as development continues.
id: XAO:0003046
has_related_synonym: mesenchymal tissue

Axiom
database_cross_reference: AAO:0010427
annotated target: Portion of embryonic tissue consisting of loosely organized, undifferentiated mesodermal or neural crest derived cells, that have specific properties (they are migratory, have no polarity). Mesenchyme cells are incorporated into a wide variety of structures including connective tissue, blood, bone and cartilage as development continues.
database_cross_reference: XAO:CJZ
annotated property: definition
annotated source: mesenchyme

nerve
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: nervous system
database_cross_reference: AAO:0011070
definition: Portion of tissue that consists of a fasciculated group of axons.
id: XAO:0003047

Axiom
annotated target: Portion of tissue that consists of a fasciculated group of axons.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: nerve

egg
type: Class
subclass of: gamete
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: oocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000093
definition: A mature female germ cell that is capable of initiating formation of a new individual by fusion with a male gamete.
database_cross_reference: CL:0000025
id: XAO:0003048
has_related_synonym: ovum
has_related_synonym: unfertilized egg

Axiom
annotated target: A mature female germ cell that is capable of initiating formation of a new individual by fusion with a male gamete.
database_cross_reference: NLM:gamete
annotated property: definition
annotated source: egg

adipose tissue
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000001
definition: Connective tissue in which fat is stored.
id: XAO:0003049

Axiom
annotated target: Connective tissue in which fat is stored.
database_cross_reference: NLM:adipose+tissue
annotated property: definition
annotated source: adipose tissue

fat body
type: Class
subclass of: adipose tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000157
definition: Anatomical structure associated with the gonads which vary in form among amphibians but are primarily composed of adipose tissue and are thought to be a source of nutrients for the gonads. A body of adipose tissue, in the form of finger-like projections, usually associated with the anterior end of the testis and ovaries. Fat bodies are suspended from the body wall by dorsal mesentry which is fused with the gonadal mesentry (the mesovarium or mesorchidium).
id: XAO:0003050

Axiom
database_cross_reference: AAO:0000157
annotated target: Anatomical structure associated with the gonads which vary in form among amphibians but are primarily composed of adipose tissue and are thought to be a source of nutrients for the gonads. A body of adipose tissue, in the form of finger-like projections, usually associated with the anterior end of the testis and ovaries. Fat bodies are suspended from the body wall by dorsal mesentry which is fused with the gonadal mesentry (the mesovarium or mesorchidium).
database_cross_reference: ISBN:0-07-017977-8
annotated property: definition
annotated source: fat body

dorsal lateral plate region
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: lateral plate mesoderm
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
database_cross_reference: AAO:0011008
has_related_synonym: AGM region
has_exact_synonym: DLP
definition: Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo.
id: XAO:0003051
has_related_synonym: aorta-gonads-mesonephros region

Axiom
database_cross_reference: PMID:9618755
annotated target: Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo.
annotated property: definition
annotated source: dorsal lateral plate region

oviduct
type: Class
subclass of: duct
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000076
subclass of: Restriction
  on property: develops from
  some values from: Mullerian duct
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: female genitalia
definition: A simple ciliated tube through which the ovum travels from the ovaries to the cloaca and the external environment. It is lined with mucus-secreting glands that produce the jelly that surrounds the ovum.
database_cross_reference: AAO:0010533
id: XAO:0003052

Axiom
annotated target: A simple ciliated tube through which the ovum travels from the ovaries to the cloaca and the external environment. It is lined with mucus-secreting glands that produce the jelly that surrounds the ovum.
database_cross_reference: http://en.wikipedia.org/wiki/Oviduct
annotated property: definition
annotated source: oviduct

Keller explant
type: Class
subclass of: anatomical entity in vitro
definition: A rectangle of dorsal mesendoderm and ectoderm from an early-gastrula-stage Xenopus laevis embryo. It is approximately 60 deg to 90 deg wide, extending from the bottle cells to the animal pole.
id: XAO:0003053
has_obo_namespace: xenopus_anatomy_in_vitro

Axiom
annotated target: A rectangle of dorsal mesendoderm and ectoderm from an early-gastrula-stage Xenopus laevis embryo. It is approximately 60 deg to 90 deg wide, extending from the bottle cells to the animal pole.
database_cross_reference: ISBN:9780879695040
annotated property: definition
annotated source: Keller explant

stem cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
database_cross_reference: CL:0000034
id: XAO:0003054

Axiom
annotated target: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
database_cross_reference: CL:0000034
annotated property: definition
annotated source: stem cell

hematopoietic stem cell
type: Class
subclass of: stem cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: ventral blood island
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: dorsal lateral plate region
definition: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
database_cross_reference: CL:0000037
has_exact_synonym: HSC
id: XAO:0003055

Axiom
annotated target: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
database_cross_reference: CL:0000037
database_cross_reference: ZFA:0009014
annotated property: definition
annotated source: hematopoietic stem cell

anterior
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting the front surface of the body; often used to indicate the position of one structure relative to another.
id: XAO:0003056
in_subset: anatomical site slim
in_subset: sectional anatomy items

Axiom
database_cross_reference: NCIt:Anterior
annotated target: Spatial concept denoting the front surface of the body; often used to indicate the position of one structure relative to another.
annotated property: definition
annotated source: anterior

posterior
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting the back surface of the body.
id: XAO:0003057
in_subset: anatomical site slim
in_subset: sectional anatomy items

Axiom
database_cross_reference: NCIt:Posterior
annotated target: Spatial concept denoting the back surface of the body.
annotated property: definition
annotated source: posterior

larval structure
type: Class
id: XAO:0003058
deprecated: true

chondrocranium
type: Class
subclass of: cranium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0010169
definition: Structure consisting of a cartilaginous skull that begins to form during early tadpole stage.
id: XAO:0003059
has_related_synonym: cartilaginous skull

Axiom
database_cross_reference: ISBN:0471209627
annotated target: Structure consisting of a cartilaginous skull that begins to form during early tadpole stage.
annotated property: definition
annotated source: chondrocranium

skeletal system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: part of
  some values from: musculoskeletal system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
definition: Anatomical system that provides physical support to the organism.
database_cross_reference: VSAO:0000027
id: XAO:0003060

Axiom
database_cross_reference: AAO:0000566
annotated target: Anatomical system that provides physical support to the organism.
annotated property: definition
annotated source: skeletal system

forelimb skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000068
subclass of: Restriction
  on property: part of
  some values from: appendicular skeleton
database_cross_reference: AAO:0000202
definition: Skeletal structure of the paired, anterior appendages.
id: XAO:0003061

Axiom
database_cross_reference: AAO:0000202
annotated target: Skeletal structure of the paired, anterior appendages.
annotated property: definition
annotated source: forelimb skeleton

hindlimb skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: appendicular skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
database_cross_reference: AAO:0000217
definition: Skeletal structure of the paired, posterior appendages.
id: XAO:0003062
has_exact_synonym: hind limb skeleton

Axiom
database_cross_reference: AAO:0000217
annotated target: Skeletal structure of the paired, posterior appendages.
annotated property: definition
annotated source: hindlimb skeleton

pectoral girdle
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000063
subclass of: Restriction
  on property: part of
  some values from: appendicular skeleton
database_cross_reference: AAO:0000422
definition: Arched skeletal structure that supports the forelimbs, the rudiments of which can be distinguished in mesenchyme at NF stage 51, and is complete by NF stage 60.
id: XAO:0003063
has_related_synonym: shoulder girdle

Axiom
annotated target: Arched skeletal structure that supports the forelimbs, the rudiments of which can be distinguished in mesenchyme at NF stage 51, and is complete by NF stage 60.
database_cross_reference: ISBN:0471209627
database_cross_reference: NLM:pectoral+girdle
annotated property: definition
annotated source: pectoral girdle

pelvic girdle
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: part of
  some values from: appendicular skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000062
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000426
definition: Arched skeletal structure that supports the hind limbs, begins to develop at NF stage 50, and is ossified by NF stage 66.
id: XAO:0003064

Axiom
annotated target: Arched skeletal structure that supports the hind limbs, begins to develop at NF stage 50, and is ossified by NF stage 66.
database_cross_reference: ISBN:0471209627
database_cross_reference: NLM:pelvic+girdle
annotated property: definition
annotated source: pelvic girdle

forelimb bud
type: Class
subclass of: limb bud
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000066
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
database_cross_reference: AAO:0010381
definition: The anterior limb bud which develops into the fore limb; oval shaped in dorsal aspect by NF stage 50, and paddle shaped by NF stage 53; all four fingers and melanophores apparent by NF stage 54.
id: XAO:0003065

Axiom
annotated target: The anterior limb bud which develops into the fore limb; oval shaped in dorsal aspect by NF stage 50, and paddle shaped by NF stage 53; all four fingers and melanophores apparent by NF stage 54.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: forelimb bud

hindlimb bud
type: Class
subclass of: limb bud
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000068
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
database_cross_reference: AAO:0010382
definition: The bilateral thickening of the ectoderm in the region of the first noticeable at NF stage 47, and innervated by NF stage 51. The hind limb buds develop before the forelimb buds.
id: XAO:0003066
has_exact_synonym: hind limb bud

Axiom
annotated target: The bilateral thickening of the ectoderm in the region of the first noticeable at NF stage 47, and innervated by NF stage 51. The hind limb buds develop before the forelimb buds.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hindlimb bud

fore epipodium
type: Class
id: XAO:0003067
term replaced by: XAO:0004297
deprecated: true

fore mesopodium
type: Class
id: XAO:0003068
term replaced by: XAO:0003207
deprecated: true

hind propodium
type: Class
id: XAO:0003069
term replaced by: XAO:0004296
deprecated: true

hind metapodium
type: Class
id: XAO:0003070
term replaced by: XAO:0003212
deprecated: true

fore propodium
type: Class
id: XAO:0003071
term replaced by: XAO:0004295
deprecated: true

hind epipodium
type: Class
id: XAO:0003072
term replaced by: XAO:0004298
deprecated: true

postcranial axial skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: develops from
  some values from: sclerotomal cartilage
definition: Skeletal structure that has as its parts the vertebral column, located in the dorsal part of the trunk, and formed by a series of vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord.
database_cross_reference: VSAO:0000093
id: XAO:0003073
has_related_synonym: axial skeleton

Axiom
database_cross_reference: AAO:0000034
annotated target: Skeletal structure that has as its parts the vertebral column, located in the dorsal part of the trunk, and formed by a series of vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord.
annotated property: definition
annotated source: postcranial axial skeleton

vertebral column
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: part of
  some values from: postcranial axial skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: Anatomical cluster that consists of all the vertebra in the body.
id: XAO:0003074
database_cross_reference: ZFA:0001559

Axiom
annotated target: Anatomical cluster that consists of all the vertebra in the body.
database_cross_reference: VAO:0000185
annotated property: definition
annotated source: vertebral column

cranium
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: part of
  some values from: skeletal system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0000109
definition: Skeletal system that is part of the head, including the splanchnocranium, chondrocranium, and dermatocranium.
id: XAO:0003075
has_related_synonym: cranial skeleton

Axiom
annotated target: Skeletal system that is part of the head, including the splanchnocranium, chondrocranium, and dermatocranium.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: cranium

cervical vertebra
type: Class
subclass of: vertebra
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: vertebral column
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: The single vertebra that is immediately posterior to the skull, specifically the atlas, and lacks ribs.
id: XAO:0003076
has_exact_synonym: atlas

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The single vertebra that is immediately posterior to the skull, specifically the atlas, and lacks ribs.
annotated property: definition
annotated source: cervical vertebra

presacral vertebra
type: Class
subclass of: vertebra
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: vertebral column
database_cross_reference: AAO:0000612
definition: Any of the several vertebrae anterior to the pelvic or sacral region of the vertebral column.
id: XAO:0003077

Axiom
annotated target: Any of the several vertebrae anterior to the pelvic or sacral region of the vertebral column.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: presacral vertebra

sacral vertebra
type: Class
subclass of: vertebra
subclass of: Restriction
  on property: part of
  some values from: vertebral column
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Vertebra of the pelvic region of the vertebral column.
id: XAO:0003078

Axiom
annotated target: Vertebra of the pelvic region of the vertebral column.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sacral vertebra

caudal vertebra
type: Class
subclass of: vertebra
subclass of: Restriction
  on property: part of
  some values from: vertebral column
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
definition: The bones that make up the tail region of the tadpole.
id: XAO:0003079
database_cross_reference: ZFA:0000326

Axiom
annotated target: The bones that make up the tail region of the tadpole.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: caudal vertebra

urostyle
type: Class
subclass of: XAO_0004276
subclass of: Restriction
  on property: part of
  some values from: postcranial axial skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000078
database_cross_reference: AAO:0000732
definition: Rodlike caudal bony structure unique to anurans that lies within a compartment formed by the elongated, anteriorly oriented pelvic girdle. The urostyle is formed by the fusion of the coccyx and the hypochord.
id: XAO:0003080

Axiom
database_cross_reference: AAO:0000732
annotated target: Rodlike caudal bony structure unique to anurans that lies within a compartment formed by the elongated, anteriorly oriented pelvic girdle. The urostyle is formed by the fusion of the coccyx and the hypochord.
annotated property: definition
annotated source: urostyle

larynx
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: respiratory system
database_cross_reference: AAO:0000268
definition: Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located.
id: XAO:0003081

Axiom
database_cross_reference: AAO:0000268
annotated target: Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located.
annotated property: definition
annotated source: larynx

sucker
type: Class
consider: XAO:0000033
id: XAO:0003082
deprecated: true

braincase and otic capsule skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: cranium
database_cross_reference: AAO:0000052
definition: Skeleton encasing the brain and auditory apparatus.
id: XAO:0003083

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: Skeleton encasing the brain and auditory apparatus.
annotated property: definition
annotated source: braincase and otic capsule skeleton

lower jaw
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
database_cross_reference: AAO:0000272
definition: The ventral portion of the first pharyngeal arch.
id: XAO:0003084
has_related_synonym: ventral mandibular arch

Axiom
database_cross_reference: TAO:0001273
annotated target: The ventral portion of the first pharyngeal arch.
annotated property: definition
annotated source: lower jaw

Meckel's cartilage
type: Class
subclass of: cartilaginous element
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: lower jaw
subclass of: Restriction
  on property: part of
  some values from: mandibular arch
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000055
database_cross_reference: AAO:0000289
definition: Paired cartilaginous component of the lower jaw that fuses together through a median inferior labial cartilage, resulting in a single curved bar of cartilage by metamorphic climax. During metamorphosis it is surrounded by the developing dentale and goniale.
id: XAO:0003085
has_exact_synonym: cm

Axiom
database_cross_reference: PMID:3693112
annotated target: Paired cartilaginous component of the lower jaw that fuses together through a median inferior labial cartilage, resulting in a single curved bar of cartilage by metamorphic climax. During metamorphosis it is surrounded by the developing dentale and goniale.
annotated property: definition
annotated source: Meckel's cartilage

suspensorium
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: splanchnocranium
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000596
definition: Anatomical cluster consisting of the mandibular structures which connect the base of the lower jaw with the skull.
id: XAO:0003086

Axiom
annotated target: Anatomical cluster consisting of the mandibular structures which connect the base of the lower jaw with the skull.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/Suspensorium
annotated property: definition
annotated source: suspensorium

upper jaw
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: cranium
database_cross_reference: AAO:0000620
definition: The dorsal portion of the first pharyngeal arch.
id: XAO:0003087
has_related_synonym: palatoquadrate arch

Axiom
database_cross_reference: TAO:0001272
annotated target: The dorsal portion of the first pharyngeal arch.
annotated property: definition
annotated source: upper jaw

seminiferous tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: testis
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
database_cross_reference: AAO:0010399
definition: Any of the coiled tubules located in the testes in which spermatozoa are produced.
id: XAO:0003088

Axiom
database_cross_reference: AAO:0010399
annotated target: Any of the coiled tubules located in the testes in which spermatozoa are produced.
annotated property: definition
annotated source: seminiferous tubule

cranial nerve III
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Cranial nerve that runs to the eye muscles.
id: XAO:0003090
database_cross_reference: ZFA:0000405
has_related_synonym: oculomotor nerve

Axiom
annotated target: Cranial nerve that runs to the eye muscles.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve III

cranial nerve IV
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Cranial nerve, also known as the pathetic nerve, that runs to the eye muscles.
id: XAO:0003091
database_cross_reference: ZFA:0000600
has_related_synonym: pathetic nerve
has_related_synonym: trochlear nerve

Axiom
annotated target: Cranial nerve, also known as the pathetic nerve, that runs to the eye muscles.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve IV

cranial nerve V
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
definition: Cranial nerve that branches into the ophthalmic (supplying the skin of the nose and upper jaw) and the mandibular (supplying the lower jaw).
id: XAO:0003092
database_cross_reference: ZFA:0000697
has_related_synonym: trigeminal nerve

Axiom
annotated target: Cranial nerve that branches into the ophthalmic (supplying the skin of the nose and upper jaw) and the mandibular (supplying the lower jaw).
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve V

cranial nerve VI
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000061
definition: Cranial nerve, also known as the abducent nerve, that runs to the eye muscles.
id: XAO:0003093
database_cross_reference: ZFA:0000310
has_related_synonym: abducens nerve
has_related_synonym: abducent nerve

Axiom
annotated target: Cranial nerve, also known as the abducent nerve, that runs to the eye muscles.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve VI

cranial nerve VII
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: part of
  some values from: gustatory system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
definition: Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches).
id: XAO:0003094
database_cross_reference: ZFA:0000664
has_related_synonym: facial nerve

Axiom
annotated target: Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches).
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve VII

cranial nerve VIII
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: vestibuloauditory system
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Cranial nerve that runs to the ear.
id: XAO:0003095
database_cross_reference: ZFA:0000247
has_related_synonym: auditory nerve

Axiom
annotated target: Cranial nerve that runs to the ear.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve VIII

cranial nerve IX
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: gustatory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
definition: Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult).
id: XAO:0003096
database_cross_reference: ZFA:0000668
has_related_synonym: glossopharyngeal nerve

Axiom
annotated target: Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult).
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve IX

cranial nerve X
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: part of
  some values from: gustatory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart).
id: XAO:0003097
database_cross_reference: ZFA:0000453
has_related_synonym: vagal nerve
has_related_synonym: vagus nerve

Axiom
annotated target: Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart).
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: cranial nerve X

cerebellum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: hindbrain
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
definition: A dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum.
database_cross_reference: AAO:0010485
id: XAO:0003098

Axiom
annotated target: A dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum.
database_cross_reference: UBERON:0002037
annotated property: definition
annotated source: cerebellum

fourth ventricle
type: Class
subclass of: anatomical space
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: hindbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
database_cross_reference: AAO:0011043
has_exact_synonym: IVth ventricle
definition: Irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.
id: XAO:0003099

Axiom
annotated target: Irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.
database_cross_reference: UBERON:0002422
annotated property: definition
annotated source: fourth ventricle

medulla oblongata
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: hindbrain
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
database_cross_reference: AAO:0010486
definition: Posterior portion of the hindbrain which controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses.
id: XAO:0003100

Axiom
database_cross_reference: AAO:0010486
annotated target: Posterior portion of the hindbrain which controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses.
annotated property: definition
annotated source: medulla oblongata

spinal nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A mixed nerve which carries motor, sensory, and autonomic signals between the spinal cord and the body.
database_cross_reference: AAO:0011101
id: XAO:0003101

Axiom
annotated target: A mixed nerve which carries motor, sensory, and autonomic signals between the spinal cord and the body.
database_cross_reference: http://en.wikipedia.org/wiki/Spinal_nerve
annotated property: definition
annotated source: spinal nerve

transverse process
type: Class
subclass of: process
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: vertebra
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000073
database_cross_reference: AAO:0000698
definition: Any of the projections on each side of the vertebra from the point where the neural arch lamina joins the pedicel for the articulation with the head of a single-headed rib or the upper head of a double-headed rib. Also called diapophyses. They provide surfaces for the attachment of muscles. In anurans, the term transverse process is used in reference to the processes associated with the presacral and postsacral vertebrae.
id: XAO:0003102

Axiom
database_cross_reference: AAO:0000698
annotated target: Any of the projections on each side of the vertebra from the point where the neural arch lamina joins the pedicel for the articulation with the head of a single-headed rib or the upper head of a double-headed rib. Also called diapophyses. They provide surfaces for the attachment of muscles. In anurans, the term transverse process is used in reference to the processes associated with the presacral and postsacral vertebrae.
annotated property: definition
annotated source: transverse process

claw
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: part of
  some values from: hind digit
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000070
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: XAO_0004416
definition: Anatomical structure consisting of a small, pointed keratinized appendage at the end of each of the toes of the hind limbs.
id: XAO:0003103

Axiom
annotated target: Anatomical structure consisting of a small, pointed keratinized appendage at the end of each of the toes of the hind limbs.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: claw

myotome of head somite 1
type: Class
subclass of: myotome
subclass of: Restriction
  on property: develops from
  some values from: head somite 1
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000042
definition: Compartment of head somite 1 that is a precursor of muscle.
id: XAO:0003104

Axiom
annotated target: Compartment of head somite 1 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of head somite 1

myotome of head somite 2
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: develops from
  some values from: head somite 2
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
definition: Compartment of head somite 2 that is a precursor of muscle.
id: XAO:0003105

Axiom
annotated target: Compartment of head somite 2 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of head somite 2

myotome of head somite 3
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: develops from
  some values from: head somite 3
definition: Compartment of head somite 3 that is a precursor of muscle.
id: XAO:0003106

Axiom
annotated target: Compartment of head somite 3 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of head somite 3

myotome of head somite 4
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: develops from
  some values from: head somite 4
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
definition: Compartment of head somite 4 that is a precursor of muscle.
id: XAO:0003107

Axiom
annotated target: Compartment of head somite 4 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of head somite 4

myotome of trunk somite 1
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 1
definition: Compartment of trunk somite 1 that is a precursor of muscle.
id: XAO:0003108

Axiom
annotated target: Compartment of trunk somite 1 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 1

myotome of trunk somite 2
type: Class
subclass of: myotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 2
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 2 that is a precursor of muscle.
id: XAO:0003109

Axiom
annotated target: Compartment of trunk somite 2 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 2

myotome of trunk somite 3
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 3
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 3 that is a precursor of muscle.
id: XAO:0003110

Axiom
annotated target: Compartment of trunk somite 3 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 3

myotome of trunk somite 4
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 4
definition: Compartment of trunk somite 4 that is a precursor of muscle.
id: XAO:0003111

Axiom
annotated target: Compartment of trunk somite 4 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 4

sclerotome of head somite 4
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: develops from
  some values from: head somite 4
definition: Compartment of head somite 4 that is a precursor of the axial skeleton.
id: XAO:0003112

Axiom
annotated target: Compartment of head somite 4 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of head somite 4

sclerotome of trunk somite 1
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 1
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 1 that is a precursor of the axial skeleton.
id: XAO:0003113

Axiom
annotated target: Compartment of trunk somite 1 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 1

sclerotome of trunk somite 2
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 2
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000035
definition: Compartment of trunk somite 2 that is a precursor of the axial skeleton.
id: XAO:0003114

Axiom
annotated target: Compartment of trunk somite 2 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 2

sclerotome of trunk somite 3
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 3
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
definition: Compartment of trunk somite 3 that is a precursor of the axial skeleton.
id: XAO:0003115

Axiom
annotated target: Compartment of trunk somite 3 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 3

sclerotome of trunk somite 4
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 4
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
definition: Compartment of trunk somite 4 that is a precursor of the axial skeleton.
id: XAO:0003116

Axiom
annotated target: Compartment of trunk somite 4 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 4

myotome of trunk somite 5
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 5
definition: Compartment of trunk somite 5 that is a precursor of muscle.
id: XAO:0003117

Axiom
annotated target: Compartment of trunk somite 5 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 5

myotome of trunk somite 6
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 6
definition: Compartment of trunk somite 6 that is a precursor of muscle.
id: XAO:0003118

Axiom
annotated target: Compartment of trunk somite 6 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 6

myotome of trunk somite 7
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 7
definition: Compartment of trunk somite 7 that is a precursor of muscle.
id: XAO:0003119

Axiom
annotated target: Compartment of trunk somite 7 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 7

myotome of trunk somite 8
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 8
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 8 that is a precursor of muscle.
id: XAO:0003120

Axiom
annotated target: Compartment of trunk somite 8 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 8

sclerotome of trunk somite 5
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 5
definition: Compartment of trunk somite 5 that is a precursor of the axial skeleton.
id: XAO:0003121

Axiom
annotated target: Compartment of trunk somite 5 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 5

sclerotome of trunk somite 6
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 6
definition: Compartment of trunk somite 6 that is a precursor of the axial skeleton.
id: XAO:0003122

Axiom
annotated target: Compartment of trunk somite 6 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 6

sclerotome of trunk somite 7
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 7
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 7 that is a precursor of the axial skeleton.
id: XAO:0003123

Axiom
annotated target: Compartment of trunk somite 7 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 7

sclerotome of trunk somite 8
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 8
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
definition: Compartment of trunk somite 8 that is a precursor of the axial skeleton.
id: XAO:0003124

Axiom
annotated target: Compartment of trunk somite 8 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 8

myotome of trunk somite 9
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 9
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 9 that is a precursor of muscle.
id: XAO:0003125

Axiom
annotated target: Compartment of trunk somite 9 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 9

sclerotome of trunk somite 9
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 9
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 9 that is a precursor of the axial skeleton.
id: XAO:0003126

Axiom
annotated target: Compartment of trunk somite 9 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 9

sclerotome of trunk somite 10
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 10
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 10 that is a precursor of the axial skeleton.
id: XAO:0003127

Axiom
annotated target: Compartment of trunk somite 10 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 10

myotome of trunk somite 10
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 10
definition: Compartment of trunk somite 10 that is a precursor of muscle.
id: XAO:0003128

Axiom
annotated target: Compartment of trunk somite 10 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 10

sclerotome of trunk somite 11
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 11
definition: Compartment of trunk somite 11 that is a precursor of the axial skeleton.
id: XAO:0003129

Axiom
annotated target: Compartment of trunk somite 11 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 11

myotome of trunk somite 11
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 11
definition: Compartment of trunk somite 11 that is a precursor of muscle.
id: XAO:0003130

Axiom
annotated target: Compartment of trunk somite 11 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 11

sclerotome of trunk somite 12
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 12
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
definition: Compartment of trunk somite 12 that is a precursor of the axial skeleton.
id: XAO:0003131

Axiom
annotated target: Compartment of trunk somite 12 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 12

myotome of trunk somite 12
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 12
definition: Compartment of trunk somite 12 that is a precursor of muscle.
id: XAO:0003132

Axiom
annotated target: Compartment of trunk somite 12 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 12

sclerotome of trunk somite 13
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 13
definition: Compartment of trunk somite 13 that is a precursor of the axial skeleton.
id: XAO:0003133

Axiom
annotated target: Compartment of trunk somite 13 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 13

myotome of trunk somite 13
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 13
definition: Compartment of trunk somite 13 that is a precursor of muscle.
id: XAO:0003134

Axiom
annotated target: Compartment of trunk somite 13 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 13

sclerotome of trunk somite 14
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 14
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
definition: Compartment of trunk somite 14 that is a precursor of the axial skeleton.
id: XAO:0003135

Axiom
annotated target: Compartment of trunk somite 14 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 14

myotome of trunk somite 14
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 14
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
definition: Compartment of trunk somite 14 that is a precursor of muscle.
id: XAO:0003136

Axiom
annotated target: Compartment of trunk somite 14 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 14

sclerotome of trunk somite 15
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 15
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
definition: Compartment of trunk somite 15 that is a precursor of the axial skeleton.
id: XAO:0003137

Axiom
annotated target: Compartment of trunk somite 15 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 15

myotome of trunk somite 15
type: Class
subclass of: myotome
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 15
definition: Compartment of trunk somite 15 that is a precursor of muscle.
id: XAO:0003138

Axiom
annotated target: Compartment of trunk somite 15 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 15

sclerotome of trunk somite 16
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 16
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
definition: Compartment of trunk somite 16 that is a precursor of the axial skeleton.
id: XAO:0003139

Axiom
annotated target: Compartment of trunk somite 16 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 16

myotome of trunk somite 16
type: Class
subclass of: myotome
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 16
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of head somite 16 that is a precursor of muscle.
id: XAO:0003140

Axiom
annotated target: Compartment of head somite 16 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 16

sclerotome of trunk somite 17
type: Class
subclass of: sclerotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 17
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of trunk somite 17 that is a precursor of the axial skeleton.
id: XAO:0003141

Axiom
annotated target: Compartment of trunk somite 17 that is a precursor of the axial skeleton.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: sclerotome of trunk somite 17

myotome of trunk somite 17
type: Class
subclass of: myotome
subclass of: Restriction
  on property: develops from
  some values from: trunk somite 17
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
definition: Compartment of head somite 17 that is a precursor of muscle.
id: XAO:0003142

Axiom
annotated target: Compartment of head somite 17 that is a precursor of muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myotome of trunk somite 17

tail somite
type: Class
subclass of: somite
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: tail
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
database_cross_reference: AAO:0010383
definition: Any of the somites located posterior to the trunk.
id: XAO:0003143

Axiom
annotated target: Any of the somites located posterior to the trunk.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: tail somite

amphibian papilla
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
definition: The principal auditory organ of frog that utilizes both mechanical and electrical (hair cell-based) frequency tuning mechanisms for hearing, located near the junction of the utricle and the saccule bones of the inner ear.
id: XAO:0003144

Axiom
database_cross_reference: PMID:10377339
annotated target: The principal auditory organ of frog that utilizes both mechanical and electrical (hair cell-based) frequency tuning mechanisms for hearing, located near the junction of the utricle and the saccule bones of the inner ear.
annotated property: definition
annotated source: amphibian papilla

basilar papilla
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
definition: A sensory structure in the lagenar portion of an amphibian's membranous labyrinth between the oval and round windows.
database_cross_reference: AAO:0011018
id: XAO:0003145
has_exact_synonym: papilla basilaris

Axiom
annotated target: A sensory structure in the lagenar portion of an amphibian's membranous labyrinth between the oval and round windows.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: basilar papilla

gonad
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: trunk
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000064
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000213
definition: Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins. Reproductive organ that produces and releases eggs (ovary) or sperm (testis).
id: XAO:0003146

Axiom
database_cross_reference: AAO:0000213
annotated target: Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins. Reproductive organ that produces and releases eggs (ovary) or sperm (testis).
database_cross_reference: ZFA:0000413
annotated property: definition
annotated source: gonad

spermatozoon
type: Class
subclass of: gamete
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000093
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: spermatid
definition: A mature male germ cell that develops from a spermatid.
database_cross_reference: CL:0000019
id: XAO:0003147
has_related_synonym: sperm
has_related_synonym: spermatozoa

Axiom
annotated target: spermatozoa
annotated source: spermatozoon
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: A mature male germ cell that develops from a spermatid.
database_cross_reference: CL:0000019
annotated property: definition
annotated source: spermatozoon

germ line cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: genital system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
definition: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
database_cross_reference: CL:0000039
id: XAO:0003148

Axiom
annotated target: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
database_cross_reference: ISBN:0721662544
annotated property: definition
annotated source: germ line cell

primordial germ cell
type: Class
subclass of: germ line cell
subclass of: Restriction
  on property: develops from
  some values from: germ plasm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000070
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: CL:0000670
has_exact_synonym: PGC
definition: Primitive cell type that is involved in the reproduction of the organism beginning with the sexual differentiation of the gonads at NF stage 52. In males specifically, it migrates from the genital ridge cortical region into the medullary tissue, where it forms spermatogonia. In females it is embedded in the cortical region and multiplies as oogonia.
id: XAO:0003149
has_related_synonym: primitive germ cell

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Primitive cell type that is involved in the reproduction of the organism beginning with the sexual differentiation of the gonads at NF stage 52. In males specifically, it migrates from the genital ridge cortical region into the medullary tissue, where it forms spermatogonia. In females it is embedded in the cortical region and multiplies as oogonia.
annotated property: definition
annotated source: primordial germ cell

gamete
type: Class
subclass of: germ line cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000093
definition: A mature male or female germ cell.
database_cross_reference: CL:0000300
id: XAO:0003150

Axiom
annotated target: A mature male or female germ cell.
database_cross_reference: NLM:gamete
annotated property: definition
annotated source: gamete

spermatid
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: develops from
  some values from: spermatocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000071
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: CL:0000018
definition: Male germ cell that is derived from spermatocytes and develops into spermatozoa.
id: XAO:0003151

Axiom
annotated target: Male germ cell that is derived from spermatocytes and develops into spermatozoa.
database_cross_reference: ncithesaurus:Spermatid
annotated property: definition
annotated source: spermatid

immune system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0011003
definition: Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies.
id: XAO:0003152

Axiom
annotated target: Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies.
database_cross_reference: NLM:immune+system
annotated property: definition
annotated source: immune system

larval immune system
type: Class
subclass of: immune system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
definition: The immune system of a postembryonic, hatched or immature tadpole, prior to metamorphosis.
id: XAO:0003153

Axiom
annotated target: The immune system of a postembryonic, hatched or immature tadpole, prior to metamorphosis.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: larval immune system

adult immune system
type: Class
subclass of: immune system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000093
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0011003
definition: The complete system of biological structures and processes within the adult organism that protects against disease by identifying and killing pathogens and tumor cells.
id: XAO:0003154

Axiom
annotated target: The complete system of biological structures and processes within the adult organism that protects against disease by identifying and killing pathogens and tumor cells.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: adult immune system

lymphocyte
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: immune system
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A cell of the B cell, T cell, or natural killer cell lineage.
database_cross_reference: CL:0000542
id: XAO:0003155

Axiom
annotated target: A cell of the B cell, T cell, or natural killer cell lineage.
database_cross_reference: CL:0000542
annotated property: definition
annotated source: lymphocyte

natural killer cell
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
definition: A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.
database_cross_reference: CL:0000623
has_exact_synonym: NK cell
id: XAO:0003156

Axiom
annotated target: A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.
database_cross_reference: CL:0000623
annotated property: definition
annotated source: natural killer cell

T cell
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: develops from
  some values from: thymocyte
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
database_cross_reference: CL:0000084
id: XAO:0003157

Axiom
annotated target: A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
database_cross_reference: AAO:0010311
annotated property: definition
annotated source: T cell

B cell
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: CL:0000236
definition: One of the two types of lymphocytes (the others being T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity.
id: XAO:0003158

Axiom
annotated target: One of the two types of lymphocytes (the others being T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: B cell

thymocyte
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: thymus
definition: An immature T cell located in the thymus.
id: XAO:0003159

Axiom
database_cross_reference: AAO:0010312
annotated target: An immature T cell located in the thymus.
annotated property: definition
annotated source: thymocyte

anatomical cluster
type: Class
subclass of: anatomical group
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Anatomical group that has its parts adjacent to one another.
database_cross_reference: CARO:0000041
id: XAO:0003160

Axiom
annotated target: Anatomical group that has its parts adjacent to one another.
database_cross_reference: CARO:0000041
annotated property: definition
annotated source: anatomical cluster

limb bud
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000068
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
database_cross_reference: AAO:0010375
definition: Structure that is an early outgrowth of a presumptive limb.
id: XAO:0003161

Axiom
database_cross_reference: AAO:0010375
annotated target: Structure that is an early outgrowth of a presumptive limb.
annotated property: definition
annotated source: limb bud

acellular anatomical structure
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: develops from
  some values from: embryo
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: whole organism
definition: Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue.
database_cross_reference: CARO:0000040
id: XAO:0003162

Axiom
annotated target: Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue.
database_cross_reference: CARO:0000040
annotated property: definition
annotated source: acellular anatomical structure

basal lamina
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
definition: Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue.
database_cross_reference: CARO:0000065
id: XAO:0003163

Axiom
annotated target: Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue.
database_cross_reference: CARO:0000065
annotated property: definition
annotated source: basal lamina

solid compound organ
type: Class
subclass of: compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
database_cross_reference: CARO:0000074
definition: Compound organ that does not contain macroscopic anatomical spaces.
id: XAO:0003164

Axiom
database_cross_reference: CARO:0000074
annotated target: Compound organ that does not contain macroscopic anatomical spaces.
annotated property: definition
annotated source: solid compound organ

cavitated compound organ
type: Class
subclass of: compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: CARO:0000072
definition: Compound organ that contains one or more macroscopic anatomical spaces.
id: XAO:0003165

Axiom
database_cross_reference: CARO:0000072
annotated target: Compound organ that contains one or more macroscopic anatomical spaces.
annotated property: definition
annotated source: cavitated compound organ

appendicular skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Skeletal structure that has as its parts the pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hind limbs.
database_cross_reference: VSAO:0000076
id: XAO:0003166

Axiom
database_cross_reference: AAO:0000747
annotated target: Skeletal structure that has as its parts the pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hind limbs.
annotated property: definition
annotated source: appendicular skeleton

fore metapodium
type: Class
id: XAO:0003167
term replaced by: XAO:0003208
deprecated: true

hind mesopodium
type: Class
id: XAO:0003168
term replaced by: XAO:0003211
deprecated: true

dermatocranium
type: Class
subclass of: cranium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
database_cross_reference: AAO:0010154
definition: Cranium which consists of dermally derived bones.
id: XAO:0003169

Axiom
annotated target: Cranium which consists of dermally derived bones.
database_cross_reference: TAO:0000863
annotated property: definition
annotated source: dermatocranium

neurocranium
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: cranium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
database_cross_reference: AAO:0010153
definition: Anatomical cluster that consists of the cartilages and bones that surround the brain.
id: XAO:0003170

Axiom
annotated target: Anatomical cluster that consists of the cartilages and bones that surround the brain.
database_cross_reference: TAO:0001580
annotated property: definition
annotated source: neurocranium

orbital region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cranium
database_cross_reference: AAO:0010220
definition: An anatomical cluster that is part of the cranium and structurally supports the eye.
id: XAO:0003171

Axiom
database_cross_reference: AAO:0010220
annotated target: An anatomical cluster that is part of the cranium and structurally supports the eye.
annotated property: definition
annotated source: orbital region

olfactory region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
database_cross_reference: AAO:0010206
definition: Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs.
id: XAO:0003172

Axiom
database_cross_reference: AAO:0010206
annotated target: Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs.
annotated property: definition
annotated source: olfactory region

occipital region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: cranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010199
definition: An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles.
id: XAO:0003173

Axiom
database_cross_reference: AAO:0010199
annotated target: An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles.
annotated property: definition
annotated source: occipital region

sphenoid region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: cranium
database_cross_reference: AAO:0010207
definition: Anatomical cluster that forms the floor and side walls of the middle part of the cranium.
id: XAO:0003174

Axiom
annotated target: Anatomical cluster that forms the floor and side walls of the middle part of the cranium.
database_cross_reference: TAO:0000290
annotated property: definition
annotated source: sphenoid region

otic region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
database_cross_reference: AAO:0010208
definition: Anatomical cluster that is a posterolateral part of the neurocranium and structurally supports the vestibuloauditory system.
id: XAO:0003175

Axiom
database_cross_reference: AAO:0010208
annotated target: Anatomical cluster that is a posterolateral part of the neurocranium and structurally supports the vestibuloauditory system.
annotated property: definition
annotated source: otic region

splanchnocranium
type: Class
subclass of: cranium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010157
definition: Regional skeletal system of the jaws, hyoid and branchial arches.
id: XAO:0003176

Axiom
annotated target: Regional skeletal system of the jaws, hyoid and branchial arches.
database_cross_reference: ZFA:0001216
annotated property: definition
annotated source: splanchnocranium

hyoid arch skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: part of
  some values from: hyoid arch
subclass of: Restriction
  on property: part of
  some values from: splanchnocranium
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010370
definition: Skeletal subdivision comprising the skeletal elements of the hyoid arch.
id: XAO:0003177

Axiom
annotated target: Skeletal subdivision comprising the skeletal elements of the hyoid arch.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: hyoid arch skeleton

dorsal hyoid arch skeleton
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: hyoid arch skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010371
definition: Skeletal subdivision comprising the dorsal skeletal elements of the hyoid arch.
id: XAO:0003178

Axiom
annotated target: Skeletal subdivision comprising the dorsal skeletal elements of the hyoid arch.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: dorsal hyoid arch skeleton

ventral hyoid arch skeleton
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: hyoid arch skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010372
definition: Skeletal subdivision comprising the ventral skeletal elements of the hyoid arch.
id: XAO:0003179

Axiom
annotated target: Skeletal subdivision comprising the ventral skeletal elements of the hyoid arch.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ventral hyoid arch skeleton

branchial arch skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: part of
  some values from: splanchnocranium
subclass of: Restriction
  on property: part of
  some values from: branchial arch
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010369
definition: Skeletal and cartilaginous elements of the branchial arches; the last five of the set of seven pharyngeal arches; the numbering system can be confusing; generally branchial arch #1 is the first branchial arch, or the third pharyngeal arch, but some authors do not follow this convention.
id: XAO:0003180
has_related_synonym: gill arch skeleton
has_related_synonym: pharyngeal arch skeleton 3-7
has_related_synonym: visceral arch skeleton

Axiom
database_cross_reference: PMID:8589427
annotated target: Skeletal and cartilaginous elements of the branchial arches; the last five of the set of seven pharyngeal arches; the numbering system can be confusing; generally branchial arch #1 is the first branchial arch, or the third pharyngeal arch, but some authors do not follow this convention.
annotated property: definition
annotated source: branchial arch skeleton

branchial arch skeleton 1
type: Class
subclass of: branchial arch skeleton
subclass of: Restriction
  on property: part of
  some values from: branchial arch 1
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
definition: Skeletal and cartilaginous elements of the first branchial or pharyngeal arch.
id: XAO:0003181

Axiom
annotated target: Skeletal and cartilaginous elements of the first branchial or pharyngeal arch.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: branchial arch skeleton 1

branchial arch skeleton 2
type: Class
subclass of: branchial arch skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: branchial arch 2
definition: Skeletal and cartilaginous elements of the second branchial or pharyngeal arch.
id: XAO:0003182

Axiom
annotated target: Skeletal and cartilaginous elements of the second branchial or pharyngeal arch.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: branchial arch skeleton 2

branchial arch skeleton 3
type: Class
subclass of: branchial arch skeleton
subclass of: Restriction
  on property: part of
  some values from: branchial arch 3
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
definition: Skeletal and cartilaginous elements of the third branchial or pharyngeal arch.
id: XAO:0003183

Axiom
annotated target: Skeletal and cartilaginous elements of the third branchial or pharyngeal arch.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: branchial arch skeleton 3

branchial arch skeleton 4
type: Class
subclass of: branchial arch skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: branchial arch 4
definition: Skeletal and cartilaginous elements of the forth branchial or pharyngeal arch.
id: XAO:0003184

Axiom
annotated target: Skeletal and cartilaginous elements of the forth branchial or pharyngeal arch.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: branchial arch skeleton 4

anatomical direction
type: Class
subclass of: Xenopus anatomical entity
definition: Any spatial descriptor that describes the orientation of the anatomical features of an embryo.
id: XAO:0003185

Axiom
annotated target: Any spatial descriptor that describes the orientation of the anatomical features of an embryo.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: anatomical direction

anatomical region
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: embryo
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
definition: A region of the whole organism that contains a recognizable set of structures or anatomical entities.
id: XAO:0003186

Axiom
annotated target: A region of the whole organism that contains a recognizable set of structures or anatomical entities.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: anatomical region

medial
type: Class
subclass of: anatomical direction
definition: Spatial concept pertaining to being toward the middle or inside.
id: XAO:0003187
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Medial
annotated target: Spatial concept pertaining to being toward the middle or inside.
annotated property: definition
annotated source: medial

proximal
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting a part of the body that is closer to the center of the body than another part.
id: XAO:0003188
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Proximal
annotated target: Spatial concept denoting a part of the body that is closer to the center of the body than another part.
annotated property: definition
annotated source: proximal

distal
type: Class
subclass of: anatomical direction
definition: Spatial concept denoting a part of the body that is farther away from the center of the body than another part.
id: XAO:0003189
in_subset: anatomical site slim

Axiom
database_cross_reference: NCIt:Distal
annotated target: Spatial concept denoting a part of the body that is farther away from the center of the body than another part.
annotated property: definition
annotated source: distal

anatomical space
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: develops from
  some values from: embryo
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: CARO:0000005
definition: Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures.
id: XAO:0003190

Axiom
database_cross_reference: CARO:0000005
annotated target: Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures.
annotated property: definition
annotated source: anatomical space

left atrium
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
database_cross_reference: AAO:0010247
definition: The chamber of the heart that receives blood from the lungs.
id: XAO:0003191

Axiom
annotated target: The chamber of the heart that receives blood from the lungs.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: left atrium

right atrium
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
database_cross_reference: AAO:0010248
definition: The chamber of the heart that receives blood from the sinus venosus.
id: XAO:0003192

Axiom
annotated target: The chamber of the heart that receives blood from the sinus venosus.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: right atrium

cardiac ventricle
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Cardiac chamber which consists of a wall that surrounds the cavity of a ventricle. The amphibian heart has a single ventricle and an outflow tract with an incomplete spiral septa.
database_cross_reference: UBERON:0002082
id: XAO:0003193

Axiom
annotated target: Cardiac chamber which consists of a wall that surrounds the cavity of a ventricle. The amphibian heart has a single ventricle and an outflow tract with an incomplete spiral septa.
database_cross_reference: UBERON:0002082
annotated property: definition
annotated source: cardiac ventricle

sensory system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: part of
  some values from: nervous system
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A part of the nervous system responsible for processing sensory information.
database_cross_reference: AAO:0000555
id: XAO:0003194

Axiom
annotated target: A part of the nervous system responsible for processing sensory information.
database_cross_reference: WIKI:Sensory_system
annotated property: definition
annotated source: sensory system

vestibuloauditory system
type: Class
subclass of: sensory system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
database_cross_reference: AAO:0000631
definition: The sensory system used for balance and hearing.
id: XAO:0003195

Axiom
annotated target: The sensory system used for balance and hearing.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: vestibuloauditory system

olfactory system
type: Class
subclass of: sensory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000978
definition: The sensory system used for olfaction (the sense of smell).
id: XAO:0003196

Axiom
annotated target: The sensory system used for olfaction (the sense of smell).
database_cross_reference: WIKI:Olfactory_system
annotated property: definition
annotated source: olfactory system

gustatory system
type: Class
subclass of: sensory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010577
definition: The sensory system used for the sense of taste.
id: XAO:0003197

Axiom
annotated target: The sensory system used for the sense of taste.
database_cross_reference: WIKI:Gustatory_system
annotated property: definition
annotated source: gustatory system

visual system
type: Class
subclass of: sensory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000632
definition: The sensory system used for sight.
id: XAO:0003198

Axiom
annotated target: The sensory system used for sight.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: visual system

lymphatic system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
database_cross_reference: AAO:0010522
definition: Part of the circulatory system which consists of a series of vessels which collect blood (exclusive of erythrocytes) which seep through capillary walls and return it to the veins. The lymphatic system of vasculature drains lymph fluid from the tissue spaces of most organs and returns it to the blood vasculature for recirculation. The lymphatic sytem functions in immune responses. Anurans generate a lot lymphatic fluid, largely as a consequence of their very leaky vasculature and high interstitial compliance. Lymph is ultimately pumped into the venous system by paired, dorsally located lymph hearts. Hedrick et al (2007) show that lung inflation and deflation assists lymph movement. Lymph is moved during lung deflation to the subvertebral sac from anterior and posterior lymph sacs. During lung inflation, increased lymph sac pressure moves lymph to axillary regions, where lymph hearts can return lymph to the vascular space (see Hedrick et al 2007).
id: XAO:0003199

Axiom
database_cross_reference: AAO:0010522
annotated target: Part of the circulatory system which consists of a series of vessels which collect blood (exclusive of erythrocytes) which seep through capillary walls and return it to the veins. The lymphatic system of vasculature drains lymph fluid from the tissue spaces of most organs and returns it to the blood vasculature for recirculation. The lymphatic sytem functions in immune responses. Anurans generate a lot lymphatic fluid, largely as a consequence of their very leaky vasculature and high interstitial compliance. Lymph is ultimately pumped into the venous system by paired, dorsally located lymph hearts. Hedrick et al (2007) show that lung inflation and deflation assists lymph movement. Lymph is moved during lung deflation to the subvertebral sac from anterior and posterior lymph sacs. During lung inflation, increased lymph sac pressure moves lymph to axillary regions, where lymph hearts can return lymph to the vascular space (see Hedrick et al 2007).
database_cross_reference: XAO:curator
annotated property: definition
annotated source: lymphatic system

gut epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: alimentary system
definition: The epithelium of the gut.
id: XAO:0003200
database_cross_reference: ZFA:0005123

Axiom
annotated target: The epithelium of the gut.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: gut epithelium

oral epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: mouth
database_cross_reference: AAO:0010357
definition: Epithelium that lines the oral cavity, with many short microvilli as well as mucous cells, rodlet cells and taste buds.
id: XAO:0003201

Axiom
annotated target: Epithelium that lines the oral cavity, with many short microvilli as well as mucous cells, rodlet cells and taste buds.
database_cross_reference: UBERON:0002424
annotated property: definition
annotated source: oral epithelium

pharyngeal epithelium
type: Class
subclass of: unilaminar epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
definition: Epithelium lining the pharynx, consisting largely of simple columnar epithelium.
id: XAO:0003202
database_cross_reference: ZFA:0001174

Axiom
annotated target: Epithelium lining the pharynx, consisting largely of simple columnar epithelium.
database_cross_reference: TAO:0001174
annotated property: definition
annotated source: pharyngeal epithelium

dental epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
database_cross_reference: AAO:0011027
definition: Epithelium that is part of a developing tooth or dental organ.
id: XAO:0003203

Axiom
annotated target: Epithelium that is part of a developing tooth or dental organ.
database_cross_reference: ZFA:0005134
annotated property: definition
annotated source: dental epithelium

neural tube
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
database_cross_reference: AAO:0010617
definition: Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.
id: XAO:0003204

Axiom
database_cross_reference: AAO:0010617
annotated target: Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.
annotated property: definition
annotated source: neural tube

chondrocyte
type: Class
subclass of: chondroblast
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: cartilage tissue
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: CL:0000138
definition: Polymorphic cell type that forms cartilage.
id: XAO:0003205

Axiom
database_cross_reference: CL:0000138
annotated target: Polymorphic cell type that forms cartilage.
annotated property: definition
annotated source: chondrocyte

podocyte
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: glomus
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000067
database_cross_reference: CL:0000653
definition: Cell type that is a component of the glomus.
id: XAO:0003206

Axiom
annotated target: Cell type that is a component of the glomus.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: podocyte

carpus
type: Class
subclass of: XAO_0004276
subclass of: Restriction
  on property: part of
  some values from: XAO_0004299
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000069
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: forelimb skeleton
definition: The cluster of bones in the wrist between the radius, ulna and metacarpus, they do not belong to individual finger, but allow the wrist to move and rotate.
database_cross_reference: UBERON:0001435
id: XAO:0003207

Axiom
database_cross_reference: ISBN:0-07-017977-8
annotated target: The cluster of bones in the wrist between the radius, ulna and metacarpus, they do not belong to individual finger, but allow the wrist to move and rotate.
annotated property: definition
annotated source: carpus

metacarpus
type: Class
subclass of: XAO_0004276
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000069
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004299
subclass of: Restriction
  on property: part of
  some values from: forelimb skeleton
definition: Each of the bones forming the part of the hand between the fingers and the wrist.
id: XAO:0003208

Axiom
annotated target: Each of the bones forming the part of the hand between the fingers and the wrist.
database_cross_reference: http://www.infovisual.info/02/028_en.html
annotated property: definition
annotated source: metacarpus

radio-ulna
type: Class
subclass of: endochondral bone
subclass of: Restriction
  on property: part of
  some values from: XAO_0004297
subclass of: Restriction
  on property: part of
  some values from: forelimb skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000068
database_cross_reference: AAO:0000901
definition: Either of the paired, long bones of endochondral origin formed by the fusion of the radius and ulna.
id: XAO:0003209
has_exact_synonym: radioulna
has_exact_synonym: radius-ulna

Axiom
database_cross_reference: AAO:0000901
annotated target: Either of the paired, long bones of endochondral origin formed by the fusion of the radius and ulna.
annotated property: definition
annotated source: radio-ulna

humerus
type: Class
subclass of: endochondral bone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000068
subclass of: Restriction
  on property: part of
  some values from: forelimb skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004295
database_cross_reference: AAO:0000679
definition: Either of the paired, elongate, cylindrical bones of endochondral origin that extend from the pectoral girdle to the elbows. The humerus is the long bone in the forelimb that runs from the shoulder to the elbow.
id: XAO:0003210

Axiom
database_cross_reference: AAO:0000679
annotated target: Either of the paired, elongate, cylindrical bones of endochondral origin that extend from the pectoral girdle to the elbows. The humerus is the long bone in the forelimb that runs from the shoulder to the elbow.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: humerus

tarsus
type: Class
subclass of: XAO_0004276
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: XAO_0004300
subclass of: Restriction
  on property: part of
  some values from: hindlimb skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A bone of the wrist of the hindlimb, which remains cartilaginous until NF stage 66.
database_cross_reference: UBERON:0004454
id: XAO:0003211
has_exact_synonym: tarsalia

Axiom
annotated target: A bone of the wrist of the hindlimb, which remains cartilaginous until NF stage 66.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: tarsus

metatarsus
type: Class
subclass of: XAO_0004276
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: hindlimb skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: XAO_0004300
definition: Each of the bones forming the part of the foot between the toes and the heel.
id: XAO:0003212

Axiom
annotated target: Each of the bones forming the part of the foot between the toes and the heel.
database_cross_reference: http://www.infovisual.info/02/028_en.html
annotated property: definition
annotated source: metatarsus

tibia-fibula
type: Class
subclass of: endochondral bone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: part of
  some values from: XAO_0004298
subclass of: Restriction
  on property: part of
  some values from: hindlimb skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Bone of the lower hind leg, which undergoes ossification from NF stage 56 to stage 66.
id: XAO:0003213

Axiom
annotated target: Bone of the lower hind leg, which undergoes ossification from NF stage 56 to stage 66.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: tibia-fibula

femur
type: Class
subclass of: endochondral bone
subclass of: Restriction
  on property: part of
  some values from: hindlimb skeleton
subclass of: Restriction
  on property: part of
  some values from: XAO_0004296
subclass of: Restriction
  on property: develops from
  some values from: femur rudiment
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0000889
definition: Either of the paired, elongate, cylindrical bones of endochondral origin that form the thighs, extending from the pelvic girdles to the knees. Proximal bone of the hind leg, which begins to ossify at NF stage 55.
id: XAO:0003214

Axiom
annotated target: Either of the paired, elongate, cylindrical bones of endochondral origin that form the thighs, extending from the pelvic girdles to the knees. Proximal bone of the hind leg, which begins to ossify at NF stage 55.
database_cross_reference: ISBN:0471209627
annotated property: definition
annotated source: femur

photoreceptor layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2009-07-15T02:26:17Z
definition: The layer within the retina where the photoreceptor cell receptor segments reside.
id: XAO:0003215
database_cross_reference: ZFA:0000143
has_related_synonym: retinal photoreceptor layer
created by: seger

Axiom
annotated target: The layer within the retina where the photoreceptor cell receptor segments reside.
database_cross_reference: ZFA:0000143
annotated property: definition
annotated source: photoreceptor layer

retinal neural layer
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: retina
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
creation date: 2009-07-15T02:02:33Z
database_cross_reference: AAO:0011095
definition: The layer of nerve cells in the retina.
id: XAO:0003216
has_related_synonym: neural retina
created by: seger

Axiom
annotated target: The layer of nerve cells in the retina.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: retinal neural layer

retinal pigmented epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000047
subclass of: Restriction
  on property: part of
  some values from: retina
creation date: 2009-07-15T02:05:18Z
database_cross_reference: AAO:0011096
definition: The monolayer of pigmented epithelium covering the neural retina.
id: XAO:0003217
has_related_synonym: pigmented epithelium
has_related_synonym: pigmented retinal epithelium
created by: seger

Axiom
annotated target: The monolayer of pigmented epithelium covering the neural retina.
database_cross_reference: ZFA:0000144
annotated property: definition
annotated source: retinal pigmented epithelium

retinal outer plexiform layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2009-07-15T02:26:28Z
definition: The layer within the retina where the bipolar cells synapse with the photoreceptor cells.
id: XAO:0003218
database_cross_reference: ZFA:0001330
created by: seger

Axiom
annotated target: The layer within the retina where the bipolar cells synapse with the photoreceptor cells.
database_cross_reference: UBERON:0001790
annotated property: definition
annotated source: retinal outer plexiform layer

retinal outer nuclear layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
creation date: 2009-07-15T02:26:30Z
definition: The layer within the retina where the photoreceptor cell bodies reside.
id: XAO:0003219
database_cross_reference: ZFA:0001464
created by: seger

Axiom
annotated target: The layer within the retina where the photoreceptor cell bodies reside.
database_cross_reference: UBERON:0001789
annotated property: definition
annotated source: retinal outer nuclear layer

optic fiber layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-15T02:26:32Z
definition: Fiber layer adjacent the retinal ganglion cell layer which comprises their axons as they traverse to the optic nerve.
id: XAO:0003220
database_cross_reference: ZFA:0001619
created by: seger

Axiom
annotated target: Fiber layer adjacent the retinal ganglion cell layer which comprises their axons as they traverse to the optic nerve.
database_cross_reference: ZFA:0001619
annotated property: definition
annotated source: optic fiber layer

retinal inner nuclear layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-15T02:26:34Z
definition: The layer of the retina composed of the cell bodies of bipolar cells, horizontal cells, and some of the cell bodies of amacrine cells.
id: XAO:0003221
database_cross_reference: ZFA:0000119
created by: seger

Axiom
annotated target: The layer of the retina composed of the cell bodies of bipolar cells, horizontal cells, and some of the cell bodies of amacrine cells.
database_cross_reference: UBERON:0001791
annotated property: definition
annotated source: retinal inner nuclear layer

inner limiting membrane
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2009-07-15T02:26:37Z
definition: Retinal layer composed of the basal lamina of Muller cells.
id: XAO:0003222
database_cross_reference: ZFA:0001029
created by: seger

Axiom
database_cross_reference: NCIt:Inner_Limiting_Membrane
annotated target: Retinal layer composed of the basal lamina of Muller cells.
annotated property: definition
annotated source: inner limiting membrane

retinal ganglion cell layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2009-07-15T02:26:41Z
definition: Innermost nuclear layer of the retina, consisting of retinal ganglion cells, which contains neurons that project axons through the optic nerve to the brain.
id: XAO:0003223
database_cross_reference: ZFA:0000024
created by: seger

Axiom
annotated target: Innermost nuclear layer of the retina, consisting of retinal ganglion cells, which contains neurons that project axons through the optic nerve to the brain.
database_cross_reference: UBERON:0001792
annotated property: definition
annotated source: retinal ganglion cell layer

outer limiting membrane
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2009-07-15T02:26:44Z
definition: A thin fenestrated layer of the pars nervosa retinae adjacent to the outer nuclear layer and through which extend the visual rods and cones.
id: XAO:0003224
database_cross_reference: ZFA:0001331
created by: seger

Axiom
annotated target: A thin fenestrated layer of the pars nervosa retinae adjacent to the outer nuclear layer and through which extend the visual rods and cones.
database_cross_reference: NCIt:Outer_Limiting_Membrane
annotated property: definition
annotated source: outer limiting membrane

retinal inner plexiform layer
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-15T02:26:47Z
definition: The plexiform layer of the retina positioned between the inner nuclear layer and the ganglion cell layer and containing the dendrites of retinal ganglion cells and processes of bipolar and amacrine cells.
id: XAO:0003225
database_cross_reference: ZFA:0001329
created by: seger

Axiom
annotated target: The plexiform layer of the retina positioned between the inner nuclear layer and the ganglion cell layer and containing the dendrites of retinal ganglion cells and processes of bipolar and amacrine cells.
database_cross_reference: UBERON:0001795
annotated property: definition
annotated source: retinal inner plexiform layer

optic tectum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: midbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
creation date: 2009-07-15T03:37:08Z
database_cross_reference: AAO:0010609
definition: The brain structure where the two separate inputs from the two eyes are combined into a single, integrated map.
id: XAO:0003226
has_related_synonym: midbrain tectum
created by: seger
has_related_synonym: tectum
has_related_synonym: tectum opticum

Axiom
database_cross_reference: PMID:17952453
annotated target: The brain structure where the two separate inputs from the two eyes are combined into a single, integrated map.
annotated property: definition
annotated source: optic tectum

pharynx
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: alimentary system
creation date: 2009-07-16T02:04:46Z
database_cross_reference: AAO:0000967
definition: Anatomical cavity bounded by the derivatives of the branchial arches.
id: XAO:0003227
created by: seger

Axiom
database_cross_reference: AAO:0000967
annotated target: Anatomical cavity bounded by the derivatives of the branchial arches.
annotated property: definition
annotated source: pharynx

hypaxial muscle
type: Class
subclass of: skeletal muscle
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: trunk musculature
creation date: 2009-07-16T02:14:05Z
definition: Trunk muscle that lies ventral to the horizontal septum of the vertebrae.
id: XAO:0003228
has_related_synonym: body wall muscle
created by: seger

Axiom
annotated target: Trunk muscle that lies ventral to the horizontal septum of the vertebrae.
database_cross_reference: UBERON:0008777
annotated property: definition
annotated source: hypaxial muscle

epaxial muscle
type: Class
subclass of: skeletal muscle
subclass of: Restriction
  on property: part of
  some values from: trunk musculature
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-16T02:17:32Z
database_cross_reference: AAO:0000142
definition: Trunk muscle that lies dorsal to the horizontal septum.
id: XAO:0003229
has_exact_synonym: epaxial muscles
created by: seger

Axiom
annotated target: epaxial muscles
annotated source: epaxial muscle
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: Trunk muscle that lies dorsal to the horizontal septum.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: epaxial muscle

trunk musculature
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: trunk
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-16T02:18:03Z
definition: Muscle that is located posterior to the head and anterior to the tail and consists of epaxial and hypaxial muscle.
id: XAO:0003230
created by: seger

Axiom
annotated target: Muscle that is located posterior to the head and anterior to the tail and consists of epaxial and hypaxial muscle.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: trunk musculature

absorptive cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T01:12:02Z
definition: A cell that takes up stuff and metabolizes it.
database_cross_reference: CL:0000212
id: XAO:0003231
created by: seger

Axiom
annotated target: A cell that takes up stuff and metabolizes it.
database_cross_reference: CL:0000212
annotated property: definition
annotated source: absorptive cell

acid secreting cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T01:15:23Z
definition: Any of the cell types of the digestive system that secrete amino acid peptides or polypeptides.
database_cross_reference: CL:0000161
id: XAO:0003232
created by: seger

Axiom
annotated target: Any of the cell types of the digestive system that secrete amino acid peptides or polypeptides.
database_cross_reference: CL:0000161
annotated property: definition
annotated source: acid secreting cell

acinar cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000051
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: pancreas
creation date: 2009-07-20T01:16:38Z
database_cross_reference: CL:0000622
definition: Exocrine functioning cells of the pancreas.
id: XAO:0003233
created by: seger

Axiom
database_cross_reference: CL:0000622
annotated target: Exocrine functioning cells of the pancreas.
annotated property: definition
annotated source: acinar cell

alkali secreting cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T01:17:42Z
definition: A cell that secretes alkaline substances.
database_cross_reference: CL:0000435
id: XAO:0003234
created by: seger

Axiom
annotated target: A cell that secretes alkaline substances.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: alkali secreting cell

barrier cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T01:18:52Z
definition: A cell whose primary function is to prevent the transport of stuff across compartments.
database_cross_reference: CL:0000215
id: XAO:0003235
created by: seger

Axiom
annotated target: A cell whose primary function is to prevent the transport of stuff across compartments.
database_cross_reference: CL:0000215
annotated property: definition
annotated source: barrier cell

barrier epithelial cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
creation date: 2009-07-20T01:19:57Z
definition: A surface epithelial cell of stratified squamous epithelium of cornea, tongue, oral cavity, esophagus or cloaca.
database_cross_reference: CL:0000073
id: XAO:0003236
created by: seger

Axiom
annotated target: A surface epithelial cell of stratified squamous epithelium of cornea, tongue, oral cavity, esophagus or cloaca.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: barrier epithelial cell

cementoblast
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T01:23:10Z
definition: A cell of ectomesenchymal origin concerned with the formation of the layer of cementum on the roots of teeth.
database_cross_reference: CL:0000061
id: XAO:0003237
created by: seger

Axiom
annotated target: A cell of ectomesenchymal origin concerned with the formation of the layer of cementum on the roots of teeth.
database_cross_reference: ISBN:0781733901
annotated property: definition
annotated source: cementoblast

chondroblast
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: develops from
  some values from: mesodermal cell
creation date: 2009-07-20T01:24:55Z
definition: A chondroblast is a cell which originates from a mesenchymal stem cell and forms chondrocytes, commonly known as cartilage cells.
database_cross_reference: CL:0000058
id: XAO:0003238
created by: seger

Axiom
annotated target: A chondroblast is a cell which originates from a mesenchymal stem cell and forms chondrocytes, commonly known as cartilage cells.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: chondroblast

circulating cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: circulatory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T01:26:48Z
definition: A cell which moves among different tissues of the body, via blood, lymph, or other medium.
database_cross_reference: CL:0000080
id: XAO:0003239
created by: seger

Axiom
annotated target: A cell which moves among different tissues of the body, via blood, lymph, or other medium.
database_cross_reference: CL:0000080
annotated property: definition
annotated source: circulating cell

digestive enzyme secreting cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: part of
  some values from: alimentary system
creation date: 2009-07-20T01:30:09Z
definition: A type of cell, found in the digestive tract, that secrete enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body.
database_cross_reference: CL:0000470
id: XAO:0003240
has_exact_synonym: digestive enzyme secreting cells
created by: seger

Axiom
annotated target: digestive enzyme secreting cells
annotated source: digestive enzyme secreting cell
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: A type of cell, found in the digestive tract, that secrete enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body.
database_cross_reference: http://en.wikipedia.org/wiki/Digestive_enzyme
annotated property: definition
annotated source: digestive enzyme secreting cell

early embryonic cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: embryo
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000033
creation date: 2009-07-20T01:31:42Z
definition: A cell found in the embryo before the formation of all the gem layers is complete.
database_cross_reference: CL:0000007
id: XAO:0003241
created by: seger

Axiom
annotated target: A cell found in the embryo before the formation of all the gem layers is complete.
database_cross_reference: CL:0000007
annotated property: definition
annotated source: early embryonic cell

morula cell
type: Class
subclass of: early embryonic cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000017
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000019
creation date: 2009-07-20T01:32:43Z
definition: A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass.
database_cross_reference: CL:0000360
id: XAO:0003242
created by: seger

Axiom
annotated target: A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass.
database_cross_reference: CL:0000360
annotated property: definition
annotated source: morula cell

blastoderm cell
type: Class
subclass of: early embryonic cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000011
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000029
creation date: 2009-07-20T01:32:45Z
definition: An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).
database_cross_reference: CL:0000353
id: XAO:0003243
created by: seger

Axiom
annotated target: An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).
database_cross_reference: CL:0000353
annotated property: definition
annotated source: blastoderm cell

gastrula cell
type: Class
subclass of: early embryonic cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000033
creation date: 2009-07-20T01:32:48Z
definition: A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers.
database_cross_reference: CL:0000361
id: XAO:0003244
created by: seger

Axiom
annotated target: A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers.
database_cross_reference: CL:0000361
annotated property: definition
annotated source: gastrula cell

ectodermal cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: ectoderm
creation date: 2009-07-20T01:35:11Z
definition: A cell of the outer of the three germ layers of the embryo.
database_cross_reference: CL:0000221
id: XAO:0003245
has_exact_synonym: ectoderm cell
created by: seger

Axiom
annotated target: A cell of the outer of the three germ layers of the embryo.
database_cross_reference: CL:0000221
annotated property: definition
annotated source: ectodermal cell

electrically active cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T01:37:18Z
definition: A cell whose function is determined by the generation or the reception of an electric signal.
database_cross_reference: CL:0000211
id: XAO:0003246
created by: seger

Axiom
annotated target: A cell whose function is determined by the generation or the reception of an electric signal.
database_cross_reference: CL:0000211
annotated property: definition
annotated source: electrically active cell

endocrine cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: endocrine system
creation date: 2009-07-20T01:38:59Z
definition: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
database_cross_reference: CL:0000163
id: XAO:0003247
created by: seger

Axiom
annotated target: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
database_cross_reference: CL:0000163
annotated property: definition
annotated source: endocrine cell

endodermal cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: part of
  some values from: endoderm
creation date: 2009-07-20T01:40:37Z
definition: A cell of the inner of the three germ layers of the embryo.
database_cross_reference: CL:0000223
id: XAO:0003248
has_exact_synonym: endoderm cell
created by: seger

Axiom
annotated target: A cell of the inner of the three germ layers of the embryo.
database_cross_reference: CL:0000223
annotated property: definition
annotated source: endodermal cell

epithelial cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T01:42:50Z
definition: A cell that is usually found in a two-dimensional sheet with a free surface.
database_cross_reference: CL:0000066
id: XAO:0003249
created by: seger

Axiom
annotated target: A cell that is usually found in a two-dimensional sheet with a free surface.
database_cross_reference: CL:0000066
annotated property: definition
annotated source: epithelial cell

exocrine cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T01:44:46Z
definition: A cell of an exocrine gland, i.e. a gland that discharges its secretion via a duct.
database_cross_reference: CL:0000152
id: XAO:0003250
created by: seger

Axiom
annotated target: A cell of an exocrine gland, i.e. a gland that discharges its secretion via a duct.
database_cross_reference: CL:0000152
annotated property: definition
annotated source: exocrine cell

hatching gland cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000049
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: part of
  some values from: hatching gland
creation date: 2009-07-20T01:48:20Z
database_cross_reference: CL:0000249
definition: Individual secretory cells of the hatching gland that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching.
id: XAO:0003251
created by: seger

Axiom
annotated target: Individual secretory cells of the hatching gland that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hatching gland cell

keratin accumulating cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
creation date: 2009-07-20T01:52:10Z
definition: A cell that is specialized to accumulate keratins, a family of fibrous structural proteins.
database_cross_reference: CL:0000311
id: XAO:0003252
created by: seger

Axiom
annotated target: A cell that is specialized to accumulate keratins, a family of fibrous structural proteins.
database_cross_reference: http://en.wikipedia.org/wiki/Keratin
annotated property: definition
annotated source: keratin accumulating cell

ligament cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: part of
  some values from: ligament
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T01:52:51Z
database_cross_reference: CL:0000384
definition: Type of cell that is capable of generating and maintaining the fibrous connective tissue of the ligament.
id: XAO:0003253
created by: seger

Axiom
annotated target: Type of cell that is capable of generating and maintaining the fibrous connective tissue of the ligament.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ligament cell

Merkel cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
creation date: 2009-07-20T01:56:02Z
definition: A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute.
database_cross_reference: CL:0000242
id: XAO:0003254
created by: seger

Axiom
annotated target: A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute.
database_cross_reference: CL:0000242
annotated property: definition
annotated source: Merkel cell

mesodermal cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
creation date: 2009-07-20T02:00:17Z
definition: A cell of the middle germ layer of the embryo.
database_cross_reference: CL:0000222
id: XAO:0003255
has_exact_synonym: mesoderm cell
created by: seger

Axiom
annotated target: A cell of the middle germ layer of the embryo.
database_cross_reference: CL:0000222
annotated property: definition
annotated source: mesodermal cell

mucus secreting cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T02:06:11Z
definition: A type of epithelial cell, found in the epidermis and digestive system, whose function is to secrete mucin, which dissolves in water to form protective mucus.
database_cross_reference: CL:0000319
id: XAO:0003256
created by: seger

Axiom
annotated target: A type of epithelial cell, found in the epidermis and digestive system, whose function is to secrete mucin, which dissolves in water to form protective mucus.
database_cross_reference: http://en.wikipedia.org/wiki/Mucus
annotated property: definition
annotated source: mucus secreting cell

myelin accumulating cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2009-07-20T02:06:51Z
definition: A cell that is specialized to accumulate myelin.
database_cross_reference: CL:0000328
id: XAO:0003257
created by: seger

Axiom
annotated target: A cell that is specialized to accumulate myelin.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: myelin accumulating cell

neuromast mantle cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: skin
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-07-20T02:07:36Z
definition: A non-sensory cell surrounding the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secreting cupula in which the ciliary bundles of all the hair cells are embedded.
database_cross_reference: CL:0000851
id: XAO:0003258
created by: seger

Axiom
annotated target: A non-sensory cell surrounding the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secreting cupula in which the ciliary bundles of all the hair cells are embedded.
database_cross_reference: CL:0000851
annotated property: definition
annotated source: neuromast mantle cell

neuromast support cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: skin
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2009-07-20T02:09:08Z
definition: A non-sensory cell of the neuromast that extends between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells.
database_cross_reference: CL:0000852
id: XAO:0003259
created by: seger

Axiom
annotated target: A non-sensory cell of the neuromast that extends between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells.
database_cross_reference: CL:0000852
annotated property: definition
annotated source: neuromast support cell

nucleate erythrocyte
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2009-07-20T02:10:45Z
definition: An erythrocyte having a nucleus.
database_cross_reference: CL:0000562
id: XAO:0003260
created by: seger

Axiom
annotated target: An erythrocyte having a nucleus.
database_cross_reference: CL:0000562
annotated property: definition
annotated source: nucleate erythrocyte

olfactory epithelial support cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: olfactory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
creation date: 2009-07-20T02:14:47Z
definition: A non-ciliated columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium.
database_cross_reference: CL:0000853
id: XAO:0003261
created by: seger

Axiom
annotated target: A non-ciliated columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium.
database_cross_reference: CL:0000853
annotated property: definition
annotated source: olfactory epithelial support cell

oxygen accumulating cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T02:16:28Z
definition: A cell that is specialized to accumulate oxygen.
database_cross_reference: CL:0000329
id: XAO:0003262
created by: seger

Axiom
annotated target: A cell that is specialized to accumulate oxygen.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: oxygen accumulating cell

paracrine cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T02:17:10Z
definition: A secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it.
database_cross_reference: CL:0000512
id: XAO:0003263
created by: seger

Axiom
annotated target: A secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it.
database_cross_reference: CL:0000512
annotated property: definition
annotated source: paracrine cell

pericyte
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
creation date: 2009-07-20T02:21:51Z
definition: A slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.
database_cross_reference: CL:0000669
id: XAO:0003264
created by: seger

Axiom
annotated target: A slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.
database_cross_reference: CL:0000669
annotated property: definition
annotated source: pericyte

somatic stem cell
type: Class
subclass of: stem cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2009-07-20T02:25:31Z
definition: A stem cell that can give rise to cell types of the body other than those of the germ-line.
database_cross_reference: CL:0000723
id: XAO:0003265
created by: seger

Axiom
annotated target: A stem cell that can give rise to cell types of the body other than those of the germ-line.
database_cross_reference: CL:0000723
annotated property: definition
annotated source: somatic stem cell

liver primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: develops from
  some values from: hepato-pancreatic progenitor cell
creation date: 2009-07-20T04:05:12Z
database_cross_reference: AAO:0011058
definition: Embryonic primordium consisting of an endodermal thickening that develops into the liver.
id: XAO:0003266
has_broad_synonym: liver
has_related_synonym: liver bud
created by: seger

Axiom
annotated target: Embryonic primordium consisting of an endodermal thickening that develops into the liver.
database_cross_reference: ZFA:0000124
annotated property: definition
annotated source: liver primordium

kidney
type: Class
subclass of: cavitated compound organ
subclass of: Restriction
  on property: part of
  some values from: urinary system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: develops from
  some values from: pronephric mesenchyme
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2009-08-25T11:34:29Z
database_cross_reference: AAO:0000250
definition: Either of the pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.
id: XAO:0003267
has_exact_synonym: mesonephros
has_exact_synonym: pronephros
created by: seger

Axiom
database_cross_reference: AAO:0000250
annotated target: Either of the pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.
annotated property: definition
annotated source: kidney

cardiac progenitor cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000022
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: fused heart primordium
creation date: 2009-12-01T04:42:20Z
has_exact_synonym: CPC
definition: Presumptive precardiac cells which lie as paired primordia 30 to 45 degree on either side of the dorsal midline of the Xenopus embryo, and as gastrulation proceeds, these migrate laterally, eventually fusing at the anterior ventral midline, where they differentiate into cardiac tissue. Cells that give rise to the linear heart tube of the fused heart primordium and derive from the cardiac crescent.
id: XAO:0003268
created by: seger

Axiom
database_cross_reference: PMID:17194606
database_cross_reference: PMID:2340810
annotated target: Presumptive precardiac cells which lie as paired primordia 30 to 45 degree on either side of the dorsal midline of the Xenopus embryo, and as gastrulation proceeds, these migrate laterally, eventually fusing at the anterior ventral midline, where they differentiate into cardiac tissue. Cells that give rise to the linear heart tube of the fused heart primordium and derive from the cardiac crescent.
annotated property: definition
annotated source: cardiac progenitor cell

jaw muscle
type: Class
subclass of: XAO_0004322
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2009-12-01T04:45:17Z
definition: Type of muscle that arises in the zygomatic arch and closes the jaw.
id: XAO:0003269
created by: seger

Axiom
annotated target: Type of muscle that arises in the zygomatic arch and closes the jaw.
database_cross_reference: UBERON:0003681
annotated property: definition
annotated source: jaw muscle

duct
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-06-16T10:41:29Z
definition: A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination.
database_cross_reference: UBERON:0000058
id: XAO:0004000
has_related_synonym: ducts
created by: lab

Axiom
annotated target: ducts
annotated source: duct
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination.
database_cross_reference: UBERON:0000058
annotated property: definition
annotated source: duct

portion of organism substance
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
creation date: 2011-06-16T10:56:39Z
definition: Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.
id: XAO:0004001
database_cross_reference: ZFA:0000007
created by: lab

Axiom
database_cross_reference: CARO:0000004
annotated target: Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.
annotated property: definition
annotated source: portion of organism substance

lateral line
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: lateral line system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-06-16T11:03:34Z
definition: Any of the sense organs that detect vibrations carried through water. They develop from a specialized series of dorsolateral ectodermal placodes named lateral line placodes.
id: XAO:0004002
database_cross_reference: ZFA:0001469
created by: lab

Axiom
annotated target: Any of the sense organs that detect vibrations carried through water. They develop from a specialized series of dorsolateral ectodermal placodes named lateral line placodes.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: lateral line

anatomical line
type: Class
subclass of: Xenopus anatomical entity
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
creation date: 2011-06-16T11:18:59Z
database_cross_reference: CARO:0000008
definition: Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface.
id: XAO:0004003
created by: lab

Axiom
database_cross_reference: CARO:0000008
annotated target: Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface.
annotated property: definition
annotated source: anatomical line

atypical epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-06-20T10:55:41Z
database_cross_reference: CARO:0000071
definition: Epithelium that consists of epithelial cells not arranged in one ore more layers.
id: XAO:0004004
created by: lab

Axiom
database_cross_reference: AAO:0010057
annotated target: Epithelium that consists of epithelial cells not arranged in one ore more layers.
annotated property: definition
annotated source: atypical epithelium

extraembryonic structure
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
creation date: 2011-06-20T11:00:46Z
definition: Anatomical structure that is contiguous with the embryo and comprises portions of tissue or cells that will not contribute to the embryo.
database_cross_reference: CARO:0000042
id: XAO:0004005
created by: lab

Axiom
annotated target: Anatomical structure that is contiguous with the embryo and comprises portions of tissue or cells that will not contribute to the embryo.
database_cross_reference: ZFA:0000020
annotated property: definition
annotated source: extraembryonic structure

multilaminar epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-06-20T11:10:18Z
database_cross_reference: CARO:0000069
definition: Epithelium that consists of more than one layer of epithelial cells.
id: XAO:0004006
created by: lab

Axiom
database_cross_reference: CARO:0000069
annotated target: Epithelium that consists of more than one layer of epithelial cells.
annotated property: definition
annotated source: multilaminar epithelium

unilaminar epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-06-20T11:18:11Z
database_cross_reference: CARO:0000073
definition: Epithelium that consists of a single layer of epithelial cells.
id: XAO:0004007
created by: lab

Axiom
database_cross_reference: CARO:MAH
annotated target: Epithelium that consists of a single layer of epithelial cells.
annotated property: definition
annotated source: unilaminar epithelium

simple columnar epithelium
type: Class
subclass of: unilaminar epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-06-20T11:19:24Z
database_cross_reference: CARO:0000068
definition: Unilaminar epithelium that consists of a single layer of columnar cells.
id: XAO:0004008
created by: lab

Axiom
database_cross_reference: CARO:MAH
annotated target: Unilaminar epithelium that consists of a single layer of columnar cells.
annotated property: definition
annotated source: simple columnar epithelium

simple cuboidal epithelium
type: Class
subclass of: unilaminar epithelium
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-06-20T11:22:50Z
database_cross_reference: CARO:0000067
definition: Unilaminar epithelium that consists of a single layer of cuboidal cells.
id: XAO:0004009
created by: lab

Axiom
database_cross_reference: CARO:MAH
annotated target: Unilaminar epithelium that consists of a single layer of cuboidal cells.
annotated property: definition
annotated source: simple cuboidal epithelium

simple squamous epithelium
type: Class
subclass of: unilaminar epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-06-20T11:25:42Z
database_cross_reference: CARO:0000070
definition: Unilaminar epithelium that consists of a single layer of squamous cells.
id: XAO:0004010
created by: lab

Axiom
database_cross_reference: CARO:MAH
annotated target: Unilaminar epithelium that consists of a single layer of squamous cells.
annotated property: definition
annotated source: simple squamous epithelium

axial skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T02:37:32Z
definition: Anatomical cluster of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum.
database_cross_reference: VSAO:0000056
id: XAO:0004011
created by: xenbase3

Axiom
annotated target: Anatomical cluster of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum.
database_cross_reference: VAO:0000056
annotated property: definition
annotated source: axial skeleton

skeletal element
type: Class
subclass of: solid compound organ
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: skeleton
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T03:11:53Z
definition: Organ entity that may have different tissue compositions at different stages and typically involved in mechanical support.
database_cross_reference: VSAO:0000128
id: XAO:0004012
created by: xenbase3

Axiom
annotated target: Organ entity that may have different tissue compositions at different stages and typically involved in mechanical support.
database_cross_reference: VAO:0000128
annotated property: definition
annotated source: skeletal element

cartilaginous element
type: Class
subclass of: skeletal element
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: chondrogenic condensation
creation date: 2011-08-22T03:25:09Z
definition: Skeletal element that is composed of cartilage tissue and may be permanent or transient.
database_cross_reference: VSAO:0000000
id: XAO:0004013
has_exact_synonym: cartilage
has_exact_synonym: chondrogenic element
created by: xenbase3

Axiom
annotated target: Skeletal element that is composed of cartilage tissue and may be permanent or transient.
database_cross_reference: VAO:0000000
annotated property: definition
annotated source: cartilaginous element

membrane bone
type: Class
subclass of: skeletal element
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-08-22T03:36:02Z
definition: Bone element that arises as a result of direct ossification.
database_cross_reference: VSAO:0000023
id: XAO:0004014
created by: xenbase3

Axiom
annotated target: Bone element that arises as a result of direct ossification.
database_cross_reference: VAO:0000023
annotated property: definition
annotated source: membrane bone

dermal bone
type: Class
subclass of: membrane bone
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T03:36:25Z
definition: Skeletal element that forms superficially in the organism, usually in association with the ectoderm.
database_cross_reference: VSAO:0000130
id: XAO:0004015
created by: xenbase3

Axiom
annotated target: Skeletal element that forms superficially in the organism, usually in association with the ectoderm.
database_cross_reference: VAO:00000130
annotated property: definition
annotated source: dermal bone

replacement element
type: Class
subclass of: skeletal element
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-08-22T03:37:56Z
definition: Skeletal element that forms as a replacement or substitution of another element or tissue.
database_cross_reference: VSAO:0000135
id: XAO:0004016
created by: xenbase3

Axiom
annotated target: Skeletal element that forms as a replacement or substitution of another element or tissue.
database_cross_reference: VAO:0000135
annotated property: definition
annotated source: replacement element

endochondral element
type: Class
subclass of: replacement element
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T03:38:45Z
definition: A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification.
database_cross_reference: VSAO:0000139
id: XAO:0004017
created by: xenbase3

Axiom
annotated target: A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification.
database_cross_reference: VAO:0000139
annotated property: definition
annotated source: endochondral element

endochondral bone
type: Class
subclass of: endochondral element
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-08-22T03:39:53Z
definition: Replacement bone that forms within cartilage.
database_cross_reference: VSAO:0000145
id: XAO:0004018
has_exact_synonym: ossified chondrogenic bone
created by: xenbase3

Axiom
annotated target: Replacement bone that forms within cartilage.
database_cross_reference: VAO:0000145
annotated property: definition
annotated source: endochondral bone

vertebra
type: Class
subclass of: endochondral bone
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: vertebral column
creation date: 2011-08-22T03:44:24Z
database_cross_reference: AAO:0000691
definition: Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum.
id: XAO:0004019
created by: xenbase3

Axiom
database_cross_reference: AAO:0000691
annotated target: Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum.
annotated property: definition
annotated source: vertebra

process
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: embryo
creation date: 2011-08-22T03:58:55Z
definition: Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.
database_cross_reference: TAO:0001834
id: XAO:0004020
has_related_synonym: bony projection
has_exact_synonym: flange
has_exact_synonym: lamellae
has_exact_synonym: laminae
has_exact_synonym: projection
has_exact_synonym: ridge
has_exact_synonym: shelf
created by: xenbase3

Axiom
annotated target: Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.
database_cross_reference: TAO:0001834
annotated property: definition
annotated source: process

cell condensation
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part of
  some values from: whole organism
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T04:26:10Z
definition: Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995).
database_cross_reference: VSAO:0000006
id: XAO:0004021
created by: xenbase3

Axiom
annotated target: Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995).
database_cross_reference: VAO:0000006
annotated property: definition
annotated source: cell condensation

chondrogenic condensation
type: Class
subclass of: cell condensation
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-22T04:27:08Z
definition: Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes.
database_cross_reference: VSAO:0000092
id: XAO:0004022
has_exact_synonym: cartilaginous condensation
created by: xenbase3

Axiom
annotated target: Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes.
database_cross_reference: VAO:0000092
annotated property: definition
annotated source: chondrogenic condensation

craniofacial skeleton
type: Class
subclass of: XAO_0004279
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-08-22T04:39:54Z
definition: Cranial skeleton derived from neural crest cells.
database_cross_reference: VSAO:0000082
id: XAO:0004023
has_exact_synonym: cranio-facial skeleton
created by: xenbase3

Axiom
annotated target: Cranial skeleton derived from neural crest cells.
database_cross_reference: VAO:00000082
annotated property: definition
annotated source: craniofacial skeleton

craniofacial region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: head
creation date: 2011-08-22T04:42:44Z
definition: Anatomical cluster that encompasses the cranium and facial structures.
database_cross_reference: VSAO:0000083
id: XAO:0004024
created by: xenbase3

Axiom
annotated target: Anatomical cluster that encompasses the cranium and facial structures.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: craniofacial region

dermal skeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T04:47:40Z
definition: Skeletal system that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements.
database_cross_reference: VSAO:0000035
id: XAO:0004025
has_related_synonym: dermal skeletal system
has_related_synonym: dermoskeleton
has_related_synonym: desmoskeleton
has_related_synonym: exoskeleton
created by: xenbase3

Axiom
annotated target: Skeletal system that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements.
database_cross_reference: VAO:00000035
annotated property: definition
annotated source: dermal skeleton

endoskeleton
type: Class
subclass of: XAO_0004289
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-22T04:49:15Z
definition: Skeletal system that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues.
database_cross_reference: VSAO:0000037
id: XAO:0004026
has_exact_synonym: replacement skeleton
created by: xenbase3

Axiom
annotated target: Skeletal system that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues.
database_cross_reference: VAO:0000037
annotated property: definition
annotated source: endoskeleton

extracellular matrix
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-08-22T04:52:15Z
definition: Combination of protein fibers, ground substance and tissue fluid; typically has embedded cells.
has_exact_synonym: ECM
database_cross_reference: VSAO:0000022
id: XAO:0004027
created by: xenbase3

Axiom
annotated target: Combination of protein fibers, ground substance and tissue fluid; typically has embedded cells.
database_cross_reference: VAO:0000022
annotated property: definition
annotated source: extracellular matrix

fibrocartilage
type: Class
subclass of: cartilage tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T04:54:35Z
definition: Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns.
database_cross_reference: VSAO:0000103
id: XAO:0004028
created by: xenbase3

Axiom
annotated target: Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns.
database_cross_reference: VAO:0000103
annotated property: definition
annotated source: fibrocartilage

hyaline cartilage tissue
type: Class
subclass of: cartilage tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T04:56:37Z
definition: Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance.
database_cross_reference: VSAO:0000094
id: XAO:0004029
has_exact_synonym: hyaline cartilage
created by: xenbase3

Axiom
annotated target: Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance.
database_cross_reference: VAO:0000094
annotated property: definition
annotated source: hyaline cartilage tissue

dense regular connective tissue
type: Class
subclass of: connective tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
creation date: 2011-08-22T05:06:10Z
definition: Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts).
database_cross_reference: VSAO:0000050
id: XAO:0004030
created by: xenbase3

Axiom
annotated target: Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts).
database_cross_reference: VAO:0000050
annotated property: definition
annotated source: dense regular connective tissue

ligament
type: Class
subclass of: dense regular connective tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
creation date: 2011-08-22T05:06:59Z
definition: Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.
database_cross_reference: VSAO:0000072
id: XAO:0004031
created by: xenbase3

Axiom
annotated target: Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.
database_cross_reference: VAO:000072
annotated property: definition
annotated source: ligament

proteinaceous extracellular matrix
type: Class
subclass of: extracellular matrix
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T05:12:13Z
definition: A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
database_cross_reference: VSAO:0000021
id: XAO:0004032
created by: xenbase3

Axiom
annotated target: A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
database_cross_reference: VAO:0000021
annotated property: definition
annotated source: proteinaceous extracellular matrix

avascular GAG-rich matrix
type: Class
subclass of: proteinaceous extracellular matrix
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T05:14:07Z
definition: Proteinaceous extracellular matrix that is avascular and consists primarily of glycosaminoglycans.
database_cross_reference: VSAO:0000059
id: XAO:0004033
has_exact_synonym: avascular glycosaminoglycan-rich matrix
has_exact_synonym: cartilage matrix
has_exact_synonym: cartilage-like matrix
created by: xenbase3

Axiom
annotated target: Proteinaceous extracellular matrix that is avascular and consists primarily of glycosaminoglycans.
database_cross_reference: VAO:0000059
annotated property: definition
annotated source: avascular GAG-rich matrix

mineralized extracellular matrix
type: Class
subclass of: proteinaceous extracellular matrix
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-08-22T05:16:11Z
definition: Extracellular matrix that is mineralized.
database_cross_reference: VSAO:0000020
id: XAO:0004034
created by: xenbase3

Axiom
annotated target: Extracellular matrix that is mineralized.
database_cross_reference: VAO:0000020
annotated property: definition
annotated source: mineralized extracellular matrix

osteoid
type: Class
subclass of: bone tissue
subclass of: proteinaceous extracellular matrix
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T05:17:00Z
definition: Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue.
database_cross_reference: VSAO:0000046
id: XAO:0004035
has_exact_synonym: pre-bone
has_exact_synonym: prebone
created by: xenbase3

Axiom
annotated target: Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue.
database_cross_reference: VAO:0000046
annotated property: definition
annotated source: osteoid

mineralized avascular GAG-rich matrix
type: Class
subclass of: avascular GAG-rich matrix
subclass of: mineralized extracellular matrix
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: mineralized cartilage tissue
creation date: 2011-08-22T05:18:20Z
definition: Avascular GAG-rich matrix that is mineralized.
database_cross_reference: VSAO:0000120
id: XAO:0004036
created by: xenbase3

Axiom
annotated target: Avascular GAG-rich matrix that is mineralized.
database_cross_reference: VAO:0000120
annotated property: definition
annotated source: mineralized avascular GAG-rich matrix

non-mineralized avascular GAG-rich matrix
type: Class
subclass of: avascular GAG-rich matrix
subclass of: Restriction
  on property: part of
  some values from: non-mineralized cartilage tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-08-22T05:18:57Z
definition: Avascular GAG-rich matrix that is not mineralized.
database_cross_reference: VSAO:0000119
id: XAO:0004037
has_exact_synonym: non-mineralized cartilage
created by: xenbase3

Axiom
annotated target: Avascular GAG-rich matrix that is not mineralized.
database_cross_reference: VAO:0000119
annotated property: definition
annotated source: non-mineralized avascular GAG-rich matrix

skeletal tissue
type: Class
subclass of: connective tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T05:21:47Z
definition: Connective tissue that functions in mechanical and structural support.
database_cross_reference: VSAO:0000015
id: XAO:0004038
created by: xenbase3

Axiom
annotated target: Connective tissue that functions in mechanical and structural support.
database_cross_reference: VAO:0000015
annotated property: definition
annotated source: skeletal tissue

mineralized tissue
type: Class
subclass of: skeletal tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T05:22:34Z
definition: Skeletal tissue that is mineralized.
database_cross_reference: VSAO:0000013
id: XAO:0004039
created by: xenbase3

Axiom
annotated target: Skeletal tissue that is mineralized.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: mineralized tissue

mineralized bone tissue
type: Class
subclass of: bone tissue
subclass of: mineralized tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: mineralized extracellular matrix
subclass of: Restriction
  on property: develops from
  some values from: osteoid
creation date: 2011-08-22T05:23:02Z
definition: Bone tissue mineralized with hydroxyapatite.
database_cross_reference: VSAO:0000115
id: XAO:0004040
created by: xenbase3

Axiom
annotated target: Bone tissue mineralized with hydroxyapatite.
database_cross_reference: VAO:0000115
annotated property: definition
annotated source: mineralized bone tissue

mineralized hyaline cartilage tissue
type: Class
subclass of: mineralized tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-08-22T05:25:19Z
definition: Hyaline cartilage tissue that is mineralized.
database_cross_reference: VSAO:0000109
id: XAO:0004041
created by: xenbase3

Axiom
annotated target: Hyaline cartilage tissue that is mineralized.
database_cross_reference: VAO:0000109
annotated property: definition
annotated source: mineralized hyaline cartilage tissue

muscular system
type: Class
subclass of: anatomical system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: musculoskeletal system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
creation date: 2011-08-22T05:28:16Z
definition: Anatomical system comprising the sum of all muscles in the body.
database_cross_reference: VSAO:0000033
id: XAO:0004042
created by: xenbase3

Axiom
annotated target: Anatomical system comprising the sum of all muscles in the body.
database_cross_reference: UBERON:0000383
annotated property: definition
annotated source: muscular system

non-mineralized cartilage tissue
type: Class
subclass of: cartilage tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-22T05:30:58Z
definition: Cartilage tissue that is not mineralized.
database_cross_reference: VSAO:0000089
id: XAO:0004043
created by: xenbase3

Axiom
annotated target: Cartilage tissue that is not mineralized.
database_cross_reference: VAO:0000089
annotated property: definition
annotated source: non-mineralized cartilage tissue

non-mineralized hyaline cartilage tissue
type: Class
subclass of: hyaline cartilage tissue
subclass of: non-mineralized cartilage tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-22T05:32:35Z
definition: Hyaline cartilage tissue that is not mineralized.
database_cross_reference: VSAO:0000108
id: XAO:0004044
created by: xenbase3

Axiom
annotated target: Hyaline cartilage tissue that is not mineralized.
database_cross_reference: VAO:0000108
annotated property: definition
annotated source: non-mineralized hyaline cartilage tissue

odontogenic papilla
type: Class
subclass of: cell condensation
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-23T08:43:35Z
definition: Cell condensation that is a well-defined population of densely organized mesenchymal cells that aggregates adjacent to an epithelium.
database_cross_reference: VSAO:0000025
id: XAO:0004045
has_exact_synonym: dental papilla
has_exact_synonym: odontogenic condensation
created by: xenbase3

Axiom
annotated target: Cell condensation that is a well-defined population of densely organized mesenchymal cells that aggregates adjacent to an epithelium.
database_cross_reference: VAO:0000025
annotated property: definition
annotated source: odontogenic papilla

odontoid tissue
type: Class
subclass of: skeletal tissue
subclass of: Restriction
  on property: develops from
  some values from: odontogenic papilla
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: dermal skeleton
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
creation date: 2011-08-23T08:45:58Z
definition: Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla.
database_cross_reference: VSAO:0000063
id: XAO:0004046
has_related_synonym: dental tissue
has_exact_synonym: odontogenic tissue
created by: xenbase3

Axiom
annotated target: Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla.
database_cross_reference: VAO:0000063
annotated property: definition
annotated source: odontoid tissue

oropharyngeal papilla
type: Class
subclass of: odontogenic papilla
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-23T08:47:31Z
definition: Odontogenic papilla located along the jaws or pharyngeal skeleton.
database_cross_reference: VSAO:0000030
id: XAO:0004047
has_exact_synonym: oropharyngeal dental papilla
created by: xenbase3

Axiom
annotated target: Odontogenic papilla located along the jaws or pharyngeal skeleton.
database_cross_reference: VAO:0000030
annotated property: definition
annotated source: oropharyngeal papilla

oropharynx
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: pharynx
creation date: 2011-08-23T08:50:17Z
definition: Anatomical cluster that comprises the oral part of the pharynx.
database_cross_reference: VSAO:0000034
id: XAO:0004048
created by: xenbase3

Axiom
annotated target: Anatomical cluster that comprises the oral part of the pharynx.
database_cross_reference: UBERON:0001729
annotated property: definition
annotated source: oropharynx

perichondrium
type: Class
subclass of: connective tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-23T08:52:43Z
definition: Fibrous connective tissue that surrounds cartilage.
database_cross_reference: VSAO:0000036
id: XAO:0004049
created by: xenbase3

Axiom
annotated target: Fibrous connective tissue that surrounds cartilage.
database_cross_reference: VAO:0000036
annotated property: definition
annotated source: perichondrium

perichordal tissue
type: Class
subclass of: connective tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000074
subclass of: Restriction
  on property: part of
  some values from: notochord
creation date: 2011-08-23T08:53:53Z
definition: Fibrous connective tissue that surrounds the notochord; includes a layer of elastin.
database_cross_reference: VSAO:0000054
id: XAO:0004050
has_related_synonym: notochord
has_exact_synonym: perichordal connective tissue
has_exact_synonym: perichordal sheath
has_exact_synonym: perichordal sheath tissue
created by: xenbase3

Axiom
annotated target: Fibrous connective tissue that surrounds the notochord; includes a layer of elastin.
database_cross_reference: VAO:0000054
annotated property: definition
annotated source: perichordal tissue

dentine
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: pre-dentine
creation date: 2011-08-23T08:56:47Z
definition: Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular.
database_cross_reference: VSAO:0000069
id: XAO:0004051
has_exact_synonym: dental tissue
created by: xenbase3

Axiom
annotated target: Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular.
database_cross_reference: VAO:0000069
annotated property: definition
annotated source: dentine

pre-dentine
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-23T08:58:05Z
definition: Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix.
database_cross_reference: VSAO:0000071
id: XAO:0004052
has_exact_synonym: pre-dentine tissue
created by: xenbase3

Axiom
annotated target: Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix.
database_cross_reference: VAO:0000071
annotated property: definition
annotated source: pre-dentine

skeleton
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: part of
  some values from: skeletal system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-23T09:00:02Z
definition: Anatomical cluster that consists of all the skeletal elements (eg, bone, cartilage, and teeth) of the body.
database_cross_reference: VSAO:0000026
id: XAO:0004053
created by: xenbase3

Axiom
annotated target: Anatomical cluster that consists of all the skeletal elements (eg, bone, cartilage, and teeth) of the body.
database_cross_reference: VAO:0000026
annotated property: definition
annotated source: skeleton

vacuolated notochordal tissue
type: Class
subclass of: connective tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000074
subclass of: Restriction
  on property: part of
  some values from: notochord
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
creation date: 2011-08-23T09:02:51Z
definition: Connective tissue that is matrix-poor with large number of vacuolated cells.
database_cross_reference: VSAO:0000053
id: XAO:0004054
has_exact_synonym: notochord proper
created by: xenbase3

Axiom
annotated target: Connective tissue that is matrix-poor with large number of vacuolated cells.
database_cross_reference: VAO:0000053
annotated property: definition
annotated source: vacuolated notochordal tissue

mineralized cartilage tissue
type: Class
subclass of: cartilage tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-23T09:31:53Z
definition: Cartilage tissue that is mineralized.
database_cross_reference: VSAO:0000088
id: XAO:0004055
created by: xenbase3

Axiom
annotated target: Cartilage tissue that is mineralized.
database_cross_reference: VAO:0000088
annotated property: definition
annotated source: mineralized cartilage tissue

distal mesenchyme
type: Class
subclass of: mesenchyme
subclass of: Restriction
  on property: part of
  some values from: limb bud
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000068
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
creation date: 2011-08-24T10:22:39Z
definition: Mesenchyme cells that proliferate in the progress zone of developing limb buds.
id: XAO:0004056
created by: xenbase3

Axiom
annotated target: Mesenchyme cells that proliferate in the progress zone of developing limb buds.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: distal mesenchyme

tail tip
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: part of
  some values from: tail fin
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
creation date: 2011-08-24T10:30:32Z
definition: Portion of tissue comprising the posterior end of the tail fin.
id: XAO:0004057
created by: xenbase3

Axiom
annotated target: Portion of tissue comprising the posterior end of the tail fin.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: tail tip

ampullary nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cranial nerve VIII
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
creation date: 2011-08-24T10:33:59Z
definition: Nerve that is a branch of cranial nerve VIII and innervates the cristae ampullaris.
id: XAO:0004058
database_cross_reference: ZFA:0005144
has_exact_synonym: neural ampulla
created by: xenbase3

Axiom
annotated target: Nerve that is a branch of cranial nerve VIII and innervates the cristae ampullaris.
database_cross_reference: ZFA:0005144
annotated property: definition
annotated source: ampullary nerve

regenerating tissue
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
creation date: 2011-08-24T10:40:19Z
definition: A portion of tissue that is re-growing after damage or amputation.
id: XAO:0004059
database_cross_reference: ZFA:0005147
created by: xenbase3

Axiom
annotated target: A portion of tissue that is re-growing after damage or amputation.
database_cross_reference: ZFA:0005147
annotated property: definition
annotated source: regenerating tissue

blastema
type: Class
subclass of: regenerating tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-24T10:42:35Z
definition: A regenerating tissue composed of a proliferative mass of undifferentiated progenitor cells from which new differentiated structures arise.
database_cross_reference: UBERON:0005306
id: XAO:0004060
created by: xenbase3

Axiom
annotated target: A regenerating tissue composed of a proliferative mass of undifferentiated progenitor cells from which new differentiated structures arise.
database_cross_reference: ZFA:0001270
annotated property: definition
annotated source: blastema

dorsal fin margin
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: dorsal fin
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: part of
  some values from: dorsal tail fin
creation date: 2011-08-24T10:45:04Z
definition: The edge, and the area immediately adjacent to it, of the dorsal fin.
id: XAO:0004061
created by: xenbase3

Axiom
annotated target: The edge, and the area immediately adjacent to it, of the dorsal fin.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: dorsal fin margin

tail fin
type: Class
subclass of: fin
subclass of: Restriction
  on property: part of
  some values from: tail
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
creation date: 2011-08-24T10:47:44Z
definition: The fin at the posterior part of the body of the tadpole.
id: XAO:0004062
has_related_synonym: caudal fin
created by: xenbase3

Axiom
database_cross_reference: BTO:0001827
annotated target: The fin at the posterior part of the body of the tadpole.
annotated property: definition
annotated source: tail fin

dorsal fin
type: Class
subclass of: fin
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
creation date: 2011-08-24T10:57:00Z
database_cross_reference: AAO:0010378
definition: The unsupported flaps of epidermis-covered, loose connective tissue extending the length of the dorsal tail muscle, originating at or near the tail-body junction, and extending posteriorly to slightly beyond the tip of the notochord and tail musculature.
id: XAO:0004063
created by: xenbase3

Axiom
database_cross_reference: ISBN:0-226-55763-4
annotated target: The unsupported flaps of epidermis-covered, loose connective tissue extending the length of the dorsal tail muscle, originating at or near the tail-body junction, and extending posteriorly to slightly beyond the tip of the notochord and tail musculature.
annotated property: definition
annotated source: dorsal fin

ventral tail fin
type: Class
subclass of: fin
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
creation date: 2011-08-24T11:06:36Z
database_cross_reference: AAO:0010204
definition: The ventral part of the tail fin.
id: XAO:0004064
created by: xenbase3

Axiom
annotated target: The ventral part of the tail fin.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ventral tail fin

ventral fin margin
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: part of
  some values from: ventral tail fin
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
creation date: 2011-08-24T11:08:17Z
definition: The edge, and the area immediately adjacent to it, of the ventral fin.
id: XAO:0004065
created by: xenbase3

Axiom
annotated target: The edge, and the area immediately adjacent to it, of the ventral fin.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: ventral fin margin

vegetal endoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: endoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000020
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000011
subclass of: Restriction
  on property: develops from
  some values from: endoderm
creation date: 2011-08-24T11:12:31Z
definition: Portion of the cleavage-stage embryo below the equator and consisting of prospective endodermal cells.
id: XAO:0004066
created by: xenbase3

Axiom
database_cross_reference: ISBN:0123646200
annotated target: Portion of the cleavage-stage embryo below the equator and consisting of prospective endodermal cells.
annotated property: definition
annotated source: vegetal endoderm

suprablastoporal endoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000033
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: part of
  some values from: endoderm
creation date: 2011-08-24T11:14:55Z
definition: During gastrulation, the ring of endodermal cells that overlie the larger sub-blastoral endoderm cells.
id: XAO:0004067
created by: xenbase3

Axiom
annotated target: During gastrulation, the ring of endodermal cells that overlie the larger sub-blastoral endoderm cells.
database_cross_reference: ISBN:0123646200
annotated property: definition
annotated source: suprablastoporal endoderm

sub-blastoporal endoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: endoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000033
creation date: 2011-08-24T11:15:44Z
definition: During gastrulation, the vegetal endodermal cells that lie just below the ring of smaller suprablastoral endoderm cells.
id: XAO:0004068
created by: xenbase3

Axiom
annotated target: During gastrulation, the vegetal endodermal cells that lie just below the ring of smaller suprablastoral endoderm cells.
database_cross_reference: ISBN:0123646200
annotated property: definition
annotated source: sub-blastoporal endoderm

migratory neural crest
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: develops from
  some values from: neural crest
subclass of: Restriction
  on property: part of
  some values from: neural crest
creation date: 2011-08-24T11:22:55Z
has_related_synonym: NCMC
definition: Neural crest that lose their connections to other neuroepithelial cells during the delamination process and begin to migrate. This involves either partial or complete epithelial-to-mesenchymal transition. Numerous molecules have been demonstrated to guide a neural crest cell's migration to its target tissue.
id: XAO:0004069
has_related_synonym: neural crest migrating cells
created by: xenbase3

Axiom
annotated target: Neural crest that lose their connections to other neuroepithelial cells during the delamination process and begin to migrate. This involves either partial or complete epithelial-to-mesenchymal transition. Numerous molecules have been demonstrated to guide a neural crest cell's migration to its target tissue.
database_cross_reference: XAO:CJZ
annotated property: definition
annotated source: migratory neural crest

Axiom
annotated target: neural crest migrating cells
annotated source: migratory neural crest
has_synonym_type: PLURAL
annotated property: has_related_synonym

hypothalamus
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: diencephalon
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-24T11:29:04Z
definition: Multi-tissue structure which is part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system.
database_cross_reference: UBERON:0001898
id: XAO:0004070
created by: xenbase3

Axiom
database_cross_reference: AAO:0010484
annotated target: Multi-tissue structure which is part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system.
annotated property: definition
annotated source: hypothalamus

optic chiasm
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: diencephalon
creation date: 2011-08-24T11:35:57Z
definition: Decussation of cranial nerve II axons whereby some cross the midline and some remain ipsilateral.
database_cross_reference: UBERON:0000959
id: XAO:0004071
created by: xenbase3

Axiom
annotated target: Decussation of cranial nerve II axons whereby some cross the midline and some remain ipsilateral.
database_cross_reference: ZFA:0000556
annotated property: definition
annotated source: optic chiasm

suprachiasmatic nucleus
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: diencephalon
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2011-08-24T11:41:40Z
definition: Diencephalic nucleus that is part of the preoptic area and is ventrolateral to the caudal parvocellular preoptic nucleus.
id: XAO:0004072
database_cross_reference: ZFA:0000441
created by: xenbase3

Axiom
annotated target: Diencephalic nucleus that is part of the preoptic area and is ventrolateral to the caudal parvocellular preoptic nucleus.
database_cross_reference: ZFA:0000441
annotated property: definition
annotated source: suprachiasmatic nucleus

intersomitic region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
creation date: 2011-08-24T12:21:44Z
definition: Anatomical region between somites.
id: XAO:0004074
has_exact_synonym: intersomitic junction
created by: xenbase3

Axiom
annotated target: Anatomical region between somites.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: intersomitic region

intersomitic vessel
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: circulatory system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: intersomitic region
creation date: 2011-08-24T12:25:46Z
definition: Primary vessel sprouts that originate from the aorta and grow dorsally between the somites.
id: XAO:0004075
database_cross_reference: ZFA:0001285
has_exact_synonym: intersomitic blood vessel
created by: xenbase3

Axiom
database_cross_reference: PMID:17119151
annotated target: Primary vessel sprouts that originate from the aorta and grow dorsally between the somites.
annotated property: definition
annotated source: intersomitic vessel

intersomitic tendon
type: Class
subclass of: tendon
subclass of: Restriction
  on property: part of
  some values from: intersomitic region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
creation date: 2011-08-24T12:28:10Z
definition: A tendon located in the intersomitic region.
id: XAO:0004076
created by: xenbase3

Axiom
annotated target: A tendon located in the intersomitic region.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: intersomitic tendon

intersomitic epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: part of
  some values from: intersomitic region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
creation date: 2011-08-24T12:31:19Z
definition: Epithelium located in the intersomitic region.
id: XAO:0004077
has_exact_synonym: intersomitic membrane
created by: xenbase3

Axiom
annotated target: Epithelium located in the intersomitic region.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: intersomitic epithelium

intersomitic neuron
type: Class
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: intersomitic region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000027
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
creation date: 2011-08-24T12:34:45Z
definition: Neuron located in the intersomitic region.
id: XAO:0004078
created by: xenbase3

Axiom
annotated target: Neuron located in the intersomitic region.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: intersomitic neuron

rhombomere
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: part of
  some values from: hindbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2011-08-24T01:19:56Z
definition: Any of the 5 sequential sections of developing hindbrain, all are posterior to the midbrain-hindbrain boundary.
database_cross_reference: UBERON:0001892
id: XAO:0004079
has_related_synonym: rhombomeres
created by: xenbase3

Axiom
annotated target: rhombomeres
annotated source: rhombomere
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Any of the 5 sequential sections of developing hindbrain, all are posterior to the midbrain-hindbrain boundary.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rhombomere

rhombomere R2
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2011-08-24T02:00:45Z
definition: The 2nd most anterior segment of the developing hindbrain, and along with r3, is dorsal to brancial arch 1.
database_cross_reference: UBERON:0005569
id: XAO:0004080
has_exact_synonym: r2
has_exact_synonym: rhombomere 2
created by: xenbase3

Axiom
annotated target: The 2nd most anterior segment of the developing hindbrain, and along with r3, is dorsal to brancial arch 1.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rhombomere R2

rhombomere R3
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2011-08-24T02:04:40Z
definition: The 3rd segment of the developing hindbrain, between r2 and r4 rhombomeres, and along with r2, is dorsal to branchial arch 1.
database_cross_reference: UBERON:0005507
id: XAO:0004081
has_exact_synonym: r3
has_exact_synonym: rhombomere 3
created by: xenbase3

Axiom
annotated target: The 3rd segment of the developing hindbrain, between r2 and r4 rhombomeres, and along with r2, is dorsal to branchial arch 1.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rhombomere R3

rhombomere R4
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2011-08-24T02:06:25Z
definition: The 4th segment of the developing hindbrain, between r3 and r5 rhomomeres and dorsal to branchial arch 2.
database_cross_reference: UBERON:0005511
id: XAO:0004082
has_exact_synonym: r4
has_exact_synonym: rhombomere 4
created by: xenbase3

Axiom
annotated target: The 4th segment of the developing hindbrain, between r3 and r5 rhomomeres and dorsal to branchial arch 2.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rhombomere R4

rhombomere R5
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2011-08-24T02:08:06Z
definition: The 5th segment of the developing hindbrain, bewteen r4 and r6, and dorsal to branchial arch 3.
database_cross_reference: UBERON:0005515
id: XAO:0004083
has_exact_synonym: r5
has_exact_synonym: rhombomere 5
created by: xenbase3

Axiom
annotated target: The 5th segment of the developing hindbrain, bewteen r4 and r6, and dorsal to branchial arch 3.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rhombomere R5

rhombomere R6
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2011-08-24T02:09:39Z
definition: The 6th segment of the developing hindbrain, directly bordering the midbrain-hindbrain boundary, and dorsal to branchial arch 4.
database_cross_reference: UBERON:0005519
id: XAO:0004084
has_exact_synonym: r6
has_exact_synonym: rhombomere 6
created by: xenbase3

Axiom
annotated target: The 6th segment of the developing hindbrain, directly bordering the midbrain-hindbrain boundary, and dorsal to branchial arch 4.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rhombomere R6

ionocyte
type: Class
subclass of: epithelial cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-24T02:12:18Z
database_cross_reference: CL:0005006
definition: Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters.
id: XAO:0004085
created by: xenbase3

Axiom
database_cross_reference: CL:0005006
annotated target: Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters.
annotated property: definition
annotated source: ionocyte

presumptive midbrain-hindbrain boundary
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: central nervous system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000037
creation date: 2011-08-24T02:24:16Z
definition: Part of the neural ectoderm that will become the embryonic midbrain-hindbrain boundary.
id: XAO:0004086
database_cross_reference: ZFA:0001187
created by: xenbase3

Axiom
annotated target: Part of the neural ectoderm that will become the embryonic midbrain-hindbrain boundary.
database_cross_reference: UBERON:0007281
annotated property: definition
annotated source: presumptive midbrain-hindbrain boundary

neural fold
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
creation date: 2011-08-24T02:42:38Z
definition: One of the two edges of the neural groove.
database_cross_reference: UBERON:0005062
id: XAO:0004087
created by: xenbase3

Axiom
database_cross_reference: GO:0001842
annotated target: One of the two edges of the neural groove.
annotated property: definition
annotated source: neural fold

animal pole
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000021
creation date: 2011-08-24T03:18:10Z
definition: The pole of the animal hemisphere, the actively dividing hemisphere of the embryo.
id: XAO:0004088
created by: xenbase3

Axiom
annotated target: The pole of the animal hemisphere, the actively dividing hemisphere of the embryo.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: animal pole

periocular region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head region
creation date: 2011-08-24T03:20:21Z
definition: Anatomical region surrounding the eye but within the orbit.
id: XAO:0004089
has_related_synonym: periocular mesenchyme
created by: xenbase3

Axiom
annotated target: Anatomical region surrounding the eye but within the orbit.
database_cross_reference: http://www.merriam-webster.com/medical/periocular
annotated property: definition
annotated source: periocular region

optic field
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000033
subclass of: Restriction
  on property: part of
  some values from: pre-chordal neural plate
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000024
creation date: 2011-08-24T03:24:00Z
definition: Portion of tissue that is part of the anterior neural plate and will form the optic vesicle.
id: XAO:0004090
database_cross_reference: ZFA:0000570
has_related_synonym: eye primordium
has_related_synonym: optic primordium
created by: xenbase3

Axiom
annotated target: Portion of tissue that is part of the anterior neural plate and will form the optic vesicle.
database_cross_reference: ZFA:0000570
annotated property: definition
annotated source: optic field

non-neural ectoderm
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
creation date: 2011-08-24T03:28:19Z
definition: The portion of the embryonic ectoderm, including the preplacodal ectoderm, that does not give rise to nervous tissue.
database_cross_reference: UBERON:0005497
id: XAO:0004091
created by: xenbase3

Axiom
annotated target: The portion of the embryonic ectoderm, including the preplacodal ectoderm, that does not give rise to nervous tissue.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: non-neural ectoderm

preplacodal ectoderm
type: Class
subclass of: non-neural ectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
subclass of: Restriction
  on property: develops from
  some values from: non-neural ectoderm
creation date: 2011-08-24T03:30:53Z
has_exact_synonym: PPE
definition: The field of naive ectoderm at the anterior of the neural stage embryo. It is positioned at the border between the future epidermis and the anterior neural plate/neural crest forming regions and is subdivided into 2 distinct domains: the anterior placodal region which is anterior to the neural plate, and the posterior placodal area which is lateral to the neural crest.
id: XAO:0004092
database_cross_reference: ZFA:0007013
has_exact_synonym: pre-placodal ectoderm
created by: xenbase3

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The field of naive ectoderm at the anterior of the neural stage embryo. It is positioned at the border between the future epidermis and the anterior neural plate/neural crest forming regions and is subdivided into 2 distinct domains: the anterior placodal region which is anterior to the neural plate, and the posterior placodal area which is lateral to the neural crest.
annotated property: definition
annotated source: preplacodal ectoderm

profundal placode
type: Class
subclass of: cranial placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000045
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2011-08-24T03:36:24Z
definition: An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.
id: XAO:0004093
has_exact_synonym: profundus placode
created by: xenbase3

Axiom
annotated target: An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.
database_cross_reference: PMID:21452441
annotated property: definition
annotated source: profundal placode

lens epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: lens
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-24T03:40:12Z
definition: Epithelium which borders the anterior and equitorial region of the lens. Lens growth occurs via the differentiation of additional fibre cells from lens epithelial cells.
id: XAO:0004094
database_cross_reference: ZFA:0001326
created by: xenbase3

Axiom
annotated target: Epithelium which borders the anterior and equitorial region of the lens. Lens growth occurs via the differentiation of additional fibre cells from lens epithelial cells.
database_cross_reference: ZFA:0001326
annotated property: definition
annotated source: lens epithelium

lens transitional zone
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: lens
creation date: 2011-08-24T03:43:21Z
definition: The region of the lens of the eye where cells from the anterior epithelial capsule become transformed into the fibers that compose the lens substance.
id: XAO:0004095
created by: xenbase3

Axiom
annotated target: The region of the lens of the eye where cells from the anterior epithelial capsule become transformed into the fibers that compose the lens substance.
database_cross_reference: http://dictionary.reference.com/browse/transitional+zone
annotated property: definition
annotated source: lens transitional zone

lens fiber cell mass
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: lens
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-24T03:45:09Z
definition: Portion of tissue comprising fibers that form the bulk of the lens. They are long, thin, transparent cells.
database_cross_reference: UBERON:0002444
id: XAO:0004096
has_related_synonym: lens fiber
has_related_synonym: lens fiber cells
created by: xenbase3

Axiom
annotated target: Portion of tissue comprising fibers that form the bulk of the lens. They are long, thin, transparent cells.
database_cross_reference: UBERON:0002444
annotated property: definition
annotated source: lens fiber cell mass

horizontal cell
type: Class
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-24T03:58:01Z
definition: A neuron that laterally connects other neurons in the inner nuclear layer of the retina.
database_cross_reference: CL:0000745
id: XAO:0004097
has_related_synonym: horizontal neuron
created by: xenbase3

Axiom
annotated target: A neuron that laterally connects other neurons in the inner nuclear layer of the retina.
database_cross_reference: CL:0000745
annotated property: definition
annotated source: horizontal cell

bipolar neuron
type: Class
subclass of: interneuron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
creation date: 2011-08-24T04:01:16Z
definition: A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.
database_cross_reference: CL:0000103
id: XAO:0004098
has_related_synonym: bipolar cell
created by: xenbase3

Axiom
annotated target: A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.
database_cross_reference: CL:0000103
annotated property: definition
annotated source: bipolar neuron

amacrine cell
type: Class
subclass of: interneuron
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: retinal neural layer
creation date: 2011-08-24T04:06:40Z
database_cross_reference: CL:0000561
definition: Interneuron of the retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons.
id: XAO:0004099
has_exact_synonym: amacrine neuron
created by: xenbase3

Axiom
database_cross_reference: CL:0000561
annotated target: Interneuron of the retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons.
annotated property: definition
annotated source: amacrine cell

retinal ganglion cell
type: Class
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: retinal ganglion cell layer
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2011-08-24T04:08:45Z
database_cross_reference: CL:0000740
definition: Type of neuron that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.
id: XAO:0004100
created by: xenbase3

Axiom
database_cross_reference: CL:0000740
annotated target: Type of neuron that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.
annotated property: definition
annotated source: retinal ganglion cell

optic tract
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: diencephalon
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-25T09:25:47Z
definition: Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm.
database_cross_reference: UBERON:0001908
id: XAO:0004101
created by: xenbase3

Axiom
annotated target: Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm.
database_cross_reference: UBERON:0001908
annotated property: definition
annotated source: optic tract

pre-chordal neural plate border
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: neural plate border
subclass of: Restriction
  on property: part of
  some values from: pre-chordal neural plate
creation date: 2011-08-25T09:47:05Z
definition: The portion of the neural plate border that is anterior to the mid-hindbrain junction.
id: XAO:0004102
has_related_synonym: anterior neural plate border
created by: xenbase3

Axiom
annotated target: The portion of the neural plate border that is anterior to the mid-hindbrain junction.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: pre-chordal neural plate border

chordal neural plate border
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000023
subclass of: Restriction
  on property: part of
  some values from: chordal neural plate
subclass of: Restriction
  on property: part of
  some values from: neural plate border
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
creation date: 2011-08-25T09:47:56Z
definition: The portion of the neural plate border that is posterior to the mid-hindbrain junction.
id: XAO:0004103
created by: xenbase3

Axiom
annotated target: The portion of the neural plate border that is posterior to the mid-hindbrain junction.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: chordal neural plate border

neural plate border
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
subclass of: Restriction
  on property: part of
  some values from: neural plate
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
creation date: 2011-08-25T09:49:21Z
has_exact_synonym: NPB
definition: The boundary between non-neural ectoderm and the neural plate of neurula stage embryos, it gives rise to the neural crest and cranial placodes.
id: XAO:0004104
created by: xenbase3

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The boundary between non-neural ectoderm and the neural plate of neurula stage embryos, it gives rise to the neural crest and cranial placodes.
annotated property: definition
annotated source: neural plate border

pronephric tubule
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000045
subclass of: Restriction
  on property: part of
  some values from: pronephric nephron
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000076
creation date: 2011-08-25T09:56:54Z
definition: Any of bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts.
id: XAO:0004105
database_cross_reference: ZFA:0001558
created by: xenbase3

Axiom
annotated target: Any of bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts.
database_cross_reference: ZFA:0001558
annotated property: definition
annotated source: pronephric tubule

regenerating forelimb
type: Class
subclass of: XAO_0004311
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
creation date: 2011-08-25T10:02:27Z
definition: A portion of forelimb tissue that is re-growing after damage or amputation.
id: XAO:0004106
has_broad_synonym: forelimb
created by: xenbase3

Axiom
annotated target: A portion of forelimb tissue that is re-growing after damage or amputation.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: regenerating forelimb

regenerating hindlimb
type: Class
subclass of: XAO_0004311
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-25T10:02:56Z
definition: A portion of hind limb tissue that is re-growing after damage or amputation.
id: XAO:0004107
has_broad_synonym: hind limb
has_broad_synonym: hindlimb
has_exact_synonym: regenerating hind limb
created by: xenbase3

Axiom
annotated target: A portion of hind limb tissue that is re-growing after damage or amputation.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: regenerating hindlimb

regenerating tail
type: Class
subclass of: regenerating tissue
subclass of: Restriction
  on property: part of
  some values from: blastema
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
creation date: 2011-08-25T10:03:11Z
definition: A portion of tail tissue that is re-growing after damage or amputation.
id: XAO:0004108
has_broad_synonym: tail
has_related_synonym: tail blastema
created by: xenbase3

Axiom
annotated target: A portion of tail tissue that is re-growing after damage or amputation.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: regenerating tail

regenerating eye
type: Class
subclass of: regenerating tissue
subclass of: Restriction
  on property: part of
  some values from: blastema
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000034
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-25T10:03:22Z
definition: A portion of eye tissue that is re-growing after damage or amputation.
id: XAO:0004109
has_broad_synonym: eye
created by: xenbase3

Axiom
annotated target: A portion of eye tissue that is re-growing after damage or amputation.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: regenerating eye

eye photoreceptor cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: photoreceptor layer
creation date: 2011-08-25T10:17:43Z
definition: A cell found in the retina of the eye that is specialized to detect and transduce light.
database_cross_reference: CL:0000287
id: XAO:0004110
created by: xenbase3

Axiom
annotated target: A cell found in the retina of the eye that is specialized to detect and transduce light.
database_cross_reference: CL:0000210
annotated property: definition
annotated source: eye photoreceptor cell

retinal cone cell
type: Class
subclass of: eye photoreceptor cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
creation date: 2011-08-25T10:19:21Z
database_cross_reference: CL:0000573
definition: One of the two photoreceptor cell types in the retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.
id: XAO:0004111
has_exact_synonym: cone photoreceptor cell
created by: xenbase3

Axiom
database_cross_reference: CL:0000573
annotated target: One of the two photoreceptor cell types in the retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.
annotated property: definition
annotated source: retinal cone cell

retinal rod cell
type: Class
subclass of: eye photoreceptor cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-25T10:22:13Z
database_cross_reference: CL:0000604
definition: One of the two photoreceptor cell types of the retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.
id: XAO:0004112
has_exact_synonym: rod photoreceptor cell
created by: xenbase3

Axiom
database_cross_reference: CL:0000604
annotated target: One of the two photoreceptor cell types of the retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.
annotated property: definition
annotated source: retinal rod cell

vegetal pole
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000021
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
creation date: 2011-08-25T10:25:07Z
definition: The pole of the vegetal hemisphere, the lower, light-colored hemisphere of the embryo.
id: XAO:0004113
created by: xenbase3

Axiom
annotated target: The pole of the vegetal hemisphere, the lower, light-colored hemisphere of the embryo.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: vegetal pole

stage I oocyte
type: Class
subclass of: oocyte
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000083
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000083
creation date: 2011-08-25T10:27:57Z
definition: The developing female gamete of the pre-vitellogenic stage.
id: XAO:0004114
has_exact_synonym: pre-vitellogenic oocyte
created by: xenbase3

Axiom
annotated target: The developing female gamete of the pre-vitellogenic stage.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: stage I oocyte

stage II oocyte
type: Class
subclass of: oocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000084
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000084
creation date: 2011-08-25T10:28:59Z
definition: The developing female gamete of the early vitellogenic stage.
id: XAO:0004115
has_exact_synonym: early vitellogenic oocyte
created by: xenbase3

Axiom
annotated target: The developing female gamete of the early vitellogenic stage.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: stage II oocyte

stage III oocyte
type: Class
subclass of: oocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000085
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000085
creation date: 2011-08-25T10:30:01Z
definition: The developing female gamete of the mid-vitellogenic stage.
id: XAO:0004116
has_exact_synonym: mid-vitellogenic oocyte
created by: xenbase3

Axiom
annotated target: The developing female gamete of the mid-vitellogenic stage.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: stage III oocyte

stage IV oocyte
type: Class
subclass of: oocyte
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000086
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000086
creation date: 2011-08-25T10:30:48Z
definition: The stage in the developing female gamete where polarization along the animal-vegetal axis is established.
id: XAO:0004117
created by: xenbase3

Axiom
annotated target: The stage in the developing female gamete where polarization along the animal-vegetal axis is established.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: stage IV oocyte

stage V oocyte
type: Class
subclass of: oocyte
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000087
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000087
creation date: 2011-08-25T10:31:45Z
definition: The developing female gamete of the late-vitellogenic stage.
id: XAO:0004118
has_exact_synonym: late vitellogenic oocyte
created by: xenbase3

Axiom
annotated target: The developing female gamete of the late-vitellogenic stage.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: stage V oocyte

stage VI oocyte
type: Class
subclass of: oocyte
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000088
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000088
creation date: 2011-08-25T10:32:29Z
definition: The fully grown female gamete.
id: XAO:0004119
has_exact_synonym: post-vitellogenic oocyte
created by: xenbase3

Axiom
annotated target: The fully grown female gamete.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: stage VI oocyte

cardiac jelly
type: Class
subclass of: extracellular matrix
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
creation date: 2011-08-25T10:49:57Z
definition: A sheet of extracellular matrix that separates the outer myocardial cell layer from the inner endocardial tube in the early embryonic heart. As the heart is going through the looping stages, this extracellular matrix/cardiac jelly starts to thicken in two regions, the atrioventricular canal region and the ventricular outflow tract region. These two discrete swellings of cardiac jelly are known as cardiac cushions. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates.
database_cross_reference: UBERON:0003906
id: XAO:0004120
created by: xenbase3

Axiom
annotated target: A sheet of extracellular matrix that separates the outer myocardial cell layer from the inner endocardial tube in the early embryonic heart. As the heart is going through the looping stages, this extracellular matrix/cardiac jelly starts to thicken in two regions, the atrioventricular canal region and the ventricular outflow tract region. These two discrete swellings of cardiac jelly are known as cardiac cushions. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates.
database_cross_reference: PMID:19890915
annotated property: definition
annotated source: cardiac jelly

apical ectodermal ridge
type: Class
subclass of: proliferative region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
subclass of: Restriction
  on property: part of
  some values from: limb bud
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000068
creation date: 2011-08-25T10:53:20Z
database_cross_reference: AAO:0010760
has_exact_synonym: AER
definition: The apical ectodermal ridge is a thickened layer of ectodermal cells at the distal tip of a developing limb bud. Along with the zone of polarizing activity, it is a crucial organizing region during limb development.
id: XAO:0004121
has_exact_synonym: apical epidermal ridge
has_exact_synonym: epidermal ridge
created by: xenbase3

Axiom
annotated target: The apical ectodermal ridge is a thickened layer of ectodermal cells at the distal tip of a developing limb bud. Along with the zone of polarizing activity, it is a crucial organizing region during limb development.
database_cross_reference: WIKI:Apical_ectodermal_ridge
annotated property: definition
annotated source: apical ectodermal ridge

proliferative region
type: Class
subclass of: anatomical cluster
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000018
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-25T10:57:21Z
definition: Anatomical cluster which consists of rapidly dividing cells.
id: XAO:0004122
database_cross_reference: ZFA:0000098
created by: xenbase3

Axiom
annotated target: Anatomical cluster which consists of rapidly dividing cells.
database_cross_reference: ZFA:0000098
annotated property: definition
annotated source: proliferative region

atrioventricular canal
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
creation date: 2011-08-25T11:16:48Z
has_exact_synonym: AV canal
definition: The part of the heart connecting the atrium to the cardiac ventricle.
id: XAO:0004123
database_cross_reference: ZFA:0001315
created by: xenbase3

Axiom
database_cross_reference: PMID:10644411
annotated target: The part of the heart connecting the atrium to the cardiac ventricle.
database_cross_reference: ZFA:0001315
annotated property: definition
annotated source: atrioventricular canal

atrioventricular canal endocardium
type: Class
subclass of: endocardium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: atrioventricular canal
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-25T11:19:42Z
definition: Endocardium that is part of the atrioventricular canal.
id: XAO:0004124
database_cross_reference: ZFA:0001616
created by: xenbase3

Axiom
annotated target: Endocardium that is part of the atrioventricular canal.
database_cross_reference: PMID:10644411
database_cross_reference: ZFA:0001616
annotated property: definition
annotated source: atrioventricular canal endocardium

atrioventricular valve leaflet
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
subclass of: Restriction
  on property: part of
  some values from: heart
creation date: 2011-08-25T11:20:57Z
definition: A portion of tissue forming a cusp guarding the opening of the atrioventricular valve.
id: XAO:0004125
has_related_synonym: atrioventricular valve leaflets
created by: xenbase3

Axiom
annotated target: atrioventricular valve leaflets
annotated source: atrioventricular valve leaflet
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: A portion of tissue forming a cusp guarding the opening of the atrioventricular valve.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: atrioventricular valve leaflet

cardiac valve
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
creation date: 2011-08-25T11:22:41Z
definition: Portion of tissue that prevents regurgitation of blood from the ventricles to the atria or from the pulmonary arteries or aorta to the ventricles.
database_cross_reference: UBERON:0000946
id: XAO:0004126
has_related_synonym: heart valve
created by: xenbase3

Axiom
annotated target: Portion of tissue that prevents regurgitation of blood from the ventricles to the atria or from the pulmonary arteries or aorta to the ventricles.
database_cross_reference: UBERON:0000946
annotated property: definition
annotated source: cardiac valve

geniohyoideus
type: Class
subclass of: hypaxial muscle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
creation date: 2011-08-25T11:33:42Z
definition: One of the 3 hypaxial muscles.
id: XAO:0004127
created by: xenbase3

Axiom
annotated target: One of the 3 hypaxial muscles.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: geniohyoideus

rectus abdominus
type: Class
subclass of: hypaxial muscle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
creation date: 2011-08-25T11:34:32Z
definition: One of the 3 hypaxial muscles.
id: XAO:0004128
created by: xenbase3

Axiom
annotated target: One of the 3 hypaxial muscles.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rectus abdominus

rectus cervicus
type: Class
subclass of: hypaxial muscle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000058
creation date: 2011-08-25T11:34:53Z
definition: One of the 3 hypaxial muscles.
id: XAO:0004129
created by: xenbase3

Axiom
annotated target: One of the 3 hypaxial muscles.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: rectus cervicus

auditory hair cell
type: Class
subclass of: sensory epithelial cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
creation date: 2011-08-25T11:41:17Z
definition: A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.
database_cross_reference: CL:0000202
id: XAO:0004130
created by: xenbase3

Axiom
annotated target: A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.
database_cross_reference: CL:0000202
annotated property: definition
annotated source: auditory hair cell

horizontal crista
type: Class
subclass of: sensory epithelial cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
creation date: 2011-08-25T11:44:54Z
definition: A horizontal patch of cristae/sensory epithelia cells of the inner ear.
id: XAO:0004131
created by: xenbase3

Axiom
annotated target: A horizontal patch of cristae/sensory epithelia cells of the inner ear.
database_cross_reference: PMID:20201105
annotated property: definition
annotated source: horizontal crista

presumptive ectoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000019
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000001
creation date: 2011-08-26T08:59:00Z
definition: Presumptive structure at the animal pole of the blastula that will develop into ectoderm.
database_cross_reference: UBERON:0006601
id: XAO:0004132
created by: xenbase3

Axiom
annotated target: Presumptive structure at the animal pole of the blastula that will develop into ectoderm.
database_cross_reference: UBERON:0006601
annotated property: definition
annotated source: presumptive ectoderm

posterior crista
type: Class
subclass of: sensory epithelial cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-26T09:03:42Z
definition: A posterior patch of cristae/sensory epithelia cells of the inner ear.
database_cross_reference: UBERON:0007275
id: XAO:0004133
created by: xenbase3

Axiom
annotated target: A posterior patch of cristae/sensory epithelia cells of the inner ear.
database_cross_reference: PMID:20201105
annotated property: definition
annotated source: posterior crista

presumptive paraxial mesoderm
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: develops from
  some values from: mesoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000033
creation date: 2011-08-26T09:08:28Z
definition: Presumptive structure that will develop into paraxial mesoderm.
database_cross_reference: UBERON:0007285
id: XAO:0004134
created by: xenbase3

Axiom
annotated target: Presumptive structure that will develop into paraxial mesoderm.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: presumptive paraxial mesoderm

rhombic lip
type: Class
subclass of: primordium
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: hindbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2011-08-26T09:25:54Z
definition: The interface between the dorsal neuroepithelium and the roof plate of the fourth ventricle. The source of a number of migratory neuron populations of the hindbrain.
database_cross_reference: UBERON:0006215
id: XAO:0004135
created by: xenbase3

Axiom
annotated target: The interface between the dorsal neuroepithelium and the roof plate of the fourth ventricle. The source of a number of migratory neuron populations of the hindbrain.
database_cross_reference: UBERON:0006215
annotated property: definition
annotated source: rhombic lip

saccular macula
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: inner ear
creation date: 2011-08-26T09:31:03Z
definition: Portion of tissue that is a patch of thickened, pseudostratified epithelium in the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. The macula saccule senses linear acceleration and gravity.
database_cross_reference: UBERON:0002212
id: XAO:0004136
created by: xenbase3

Axiom
database_cross_reference: PMID:20201105
annotated target: Portion of tissue that is a patch of thickened, pseudostratified epithelium in the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. The macula saccule senses linear acceleration and gravity.
annotated property: definition
annotated source: saccular macula

anterior crista
type: Class
subclass of: sensory epithelial cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: part of
  some values from: inner ear
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-26T09:42:59Z
definition: Anterior patch of cristae/sensory epithelia cells of the inner ear.
id: XAO:0004137
database_cross_reference: ZFA:0000619
has_related_synonym: anterior cristae
created by: xenbase3

Axiom
annotated target: anterior cristae
annotated source: anterior crista
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Anterior patch of cristae/sensory epithelia cells of the inner ear.
database_cross_reference: PMID:20201105
annotated property: definition
annotated source: anterior crista

sensory epithelial cell
type: Class
subclass of: epithelial cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-26T09:52:26Z
definition: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibuloauditory systems; contain sensory cells surrounded by supportive, non-receptive cells.
database_cross_reference: CL:0000098
id: XAO:0004138
created by: xenbase3

Axiom
annotated target: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibuloauditory systems; contain sensory cells surrounded by supportive, non-receptive cells.
database_cross_reference: CL:0000098
annotated property: definition
annotated source: sensory epithelial cell

outflow tract
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: heart
creation date: 2011-08-26T10:12:24Z
definition: The portion of the heart through which blood flows into the pulmocutaneous and systemic arteries. In Xenopus the outflow tract is derived from cardiac precusor cells of the secondary heart field, and septation is incomplete.
database_cross_reference: UBERON:0004145
id: XAO:0004139
created by: xenbase3

Axiom
database_cross_reference: PMID:10644411
database_cross_reference: PMID:20671188
annotated target: The portion of the heart through which blood flows into the pulmocutaneous and systemic arteries. In Xenopus the outflow tract is derived from cardiac precusor cells of the secondary heart field, and septation is incomplete.
database_cross_reference: UBERON:0004145
annotated property: definition
annotated source: outflow tract

ventricular outflow tract
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: outflow tract
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
creation date: 2011-08-26T10:17:59Z
definition: A portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle.
database_cross_reference: UBERON:0005337
id: XAO:0004140
created by: xenbase3

Axiom
annotated target: A portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle.
database_cross_reference: PMID:10644411
database_cross_reference: UBERON:0005337
annotated property: definition
annotated source: ventricular outflow tract

spiral septum
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: ventricular outflow tract
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: secondary heart field
creation date: 2011-08-26T10:22:27Z
definition: The thin, spiral-shaped membranous structure within the ventricular outflow tract of the heart.
database_cross_reference: UBERON:0002099
id: XAO:0004141
has_related_synonym: spiral septa
created by: xenbase3

Axiom
annotated target: spiral septa
annotated source: spiral septum
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
database_cross_reference: PMID:10644411
annotated target: The thin, spiral-shaped membranous structure within the ventricular outflow tract of the heart.
annotated property: definition
annotated source: spiral septum

vestibulocochlear ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000037
subclass of: Restriction
  on property: part of
  some values from: cranial nerve VIII
subclass of: Restriction
  on property: develops from
  some values from: otic placode
creation date: 2011-08-26T10:41:25Z
definition: Ganglion which provides afferent innervation for hair cells associated with both the auditory and vestibular components of the inner ear. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII.
database_cross_reference: UBERON:0002827
id: XAO:0004142
has_exact_synonym: statoacoustic (VIII) ganglion
has_exact_synonym: statoacoustic ganglion
has_exact_synonym: vestibulocochlear VIII ganglion
has_related_synonym: vestibulocochlear ganglia
created by: xenbase3

Axiom
annotated target: vestibulocochlear ganglia
annotated source: vestibulocochlear ganglion
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Ganglion which provides afferent innervation for hair cells associated with both the auditory and vestibular components of the inner ear. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII.
database_cross_reference: PMID:21452441
annotated property: definition
annotated source: vestibulocochlear ganglion

vascular plexus
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
creation date: 2011-08-26T10:59:34Z
definition: Any network of intercommunicating blood vessels.
database_cross_reference: UBERON:0005629
id: XAO:0004143
created by: xenbase3

Axiom
annotated target: Any network of intercommunicating blood vessels.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: vascular plexus

anterior ventral blood island
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000049
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: hematological system
creation date: 2011-08-26T11:20:29Z
definition: Region that is overlapping, anterior, and dorsal to the main body of the ventral blood island.
id: XAO:0004144
has_exact_synonym: aVBI
has_broad_synonym: blood island
created by: xenbase3

Axiom
database_cross_reference: PMID:21069823
annotated target: Region that is overlapping, anterior, and dorsal to the main body of the ventral blood island.
annotated property: definition
annotated source: anterior ventral blood island

vestibular apparatus
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000059
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: inner ear
creation date: 2011-08-26T11:46:49Z
definition: A small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear.
database_cross_reference: UBERON:0005236
id: XAO:0004145
created by: xenbase3

Axiom
annotated target: A small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear.
database_cross_reference: UBERON:0005236
annotated property: definition
annotated source: vestibular apparatus

hemangioblast
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T10:27:52Z
definition: A pluripotent cell in the ventral blood island that can give rise to mesenchymal cells including erythrocytes and endothelial cells.
database_cross_reference: CL:0002418
id: XAO:0004146
created by: lab

Axiom
annotated target: A pluripotent cell in the ventral blood island that can give rise to mesenchymal cells including erythrocytes and endothelial cells.
database_cross_reference: PMID:11495698
annotated property: definition
annotated source: hemangioblast

vitelline vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: develops from
  some values from: anterior ventral blood island
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T10:36:35Z
definition: One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids.
database_cross_reference: UBERON:0005487
id: XAO:0004147
created by: lab
has_exact_synonym: vascular vitelline network
has_related_synonym: vitelline veins

Axiom
annotated target: vitelline veins
annotated source: vitelline vein
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids.
database_cross_reference: UBERON:0005487
annotated property: definition
annotated source: vitelline vein

myeloid cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T10:44:28Z
definition: A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.
database_cross_reference: CL:0000763
id: XAO:0004148
created by: lab

Axiom
annotated target: A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.
database_cross_reference: CL:0000763
annotated property: definition
annotated source: myeloid cell

endothelial cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: vascular endothelium
creation date: 2011-08-30T10:48:16Z
definition: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
database_cross_reference: CL:0000115
id: XAO:0004149
created by: lab

Axiom
annotated target: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
database_cross_reference: CL:0000115
annotated property: definition
annotated source: endothelial cell

erythroid cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: hematological system
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T10:53:48Z
definition: A immature or mature cell in the lineage leading to and including erythrocytes.
database_cross_reference: CL:0000764
id: XAO:0004150
has_related_synonym: erythroid lineage cell
created by: lab

Axiom
annotated target: A immature or mature cell in the lineage leading to and including erythrocytes.
database_cross_reference: CL:0000764
annotated property: definition
annotated source: erythroid cell

tail vasculature
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: part of
  some values from: tail
creation date: 2011-08-30T11:01:48Z
definition: Posterior vascular precursor cells of the tail region.
id: XAO:0004151
database_cross_reference: ZFA:0005037
created by: lab

Axiom
database_cross_reference: PMID:21069823
annotated target: Posterior vascular precursor cells of the tail region.
annotated property: definition
annotated source: tail vasculature

head vasculature
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
creation date: 2011-08-30T11:05:38Z
definition: The blood vessels of the head region.
id: XAO:0004152
database_cross_reference: ZFA:0001267
created by: lab

Axiom
database_cross_reference: PMID:21069823
annotated target: The blood vessels of the head region.
annotated property: definition
annotated source: head vasculature

retinal blood vessel
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: head vasculature
creation date: 2011-08-30T11:39:54Z
definition: Blood vessels of the retina. May be visible in periocular stainings.
id: XAO:0004153
created by: lab
has_related_synonym: retinal blood vessels

Axiom
annotated target: Blood vessels of the retina. May be visible in periocular stainings.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: retinal blood vessel

Axiom
annotated target: retinal blood vessels
annotated source: retinal blood vessel
has_synonym_type: PLURAL
annotated property: has_related_synonym

hyaloid blood vessel
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T11:43:24Z
database_cross_reference: UBERON:0005492
definition: Vessels that are associated with the posterior region of the lens.
id: XAO:0004154
has_exact_synonym: hyaloid blood vessels
has_exact_synonym: hyaloid vessel
has_exact_synonym: hyaloid vessels
created by: lab

Axiom
annotated target: hyaloid blood vessels
annotated source: hyaloid blood vessel
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: Vessels that are associated with the posterior region of the lens.
database_cross_reference: ZFA:0005046
annotated property: definition
annotated source: hyaloid blood vessel

Axiom
annotated target: hyaloid vessels
annotated source: hyaloid blood vessel
has_synonym_type: PLURAL
annotated property: has_exact_synonym

hyaloid artery
type: Class
subclass of: hyaloid blood vessel
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-30T11:47:17Z
definition: The hyaloid artery is a branch of the ophthalmic artery, which is itself a branch of the internal carotid artery. It is contained within the optic stalk of the eye and extends from the optic disc through the vitreous humor to the lens. Its purpose is to supply nutrient to the developing lens.
database_cross_reference: UBERON:0002270
id: XAO:0004155
created by: lab

Axiom
annotated target: The hyaloid artery is a branch of the ophthalmic artery, which is itself a branch of the internal carotid artery. It is contained within the optic stalk of the eye and extends from the optic disc through the vitreous humor to the lens. Its purpose is to supply nutrient to the developing lens.
database_cross_reference: UBERON:0002270
annotated property: definition
annotated source: hyaloid artery

hyaloid vein
type: Class
subclass of: hyaloid blood vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T11:51:28Z
database_cross_reference: UBERON:0006011
definition: Vein internal to the eye.
id: XAO:0004156
created by: lab

Axiom
database_cross_reference: UBERON:006011
annotated target: Vein internal to the eye.
annotated property: definition
annotated source: hyaloid vein

hyaloid vascular plexus
type: Class
subclass of: hyaloid blood vessel
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-08-30T11:53:20Z
definition: Network of intersecting blood vessels associated with the posterior region of the lens.
database_cross_reference: UBERON:0005607
id: XAO:0004157
created by: lab

Axiom
annotated target: Network of intersecting blood vessels associated with the posterior region of the lens.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: hyaloid vascular plexus

anterior cerebral vein
type: Class
subclass of: cerebral vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2011-08-30T12:00:30Z
definition: The anterior cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis medialis.
database_cross_reference: UBERON:0001672
id: XAO:0004158
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The anterior cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis medialis.
annotated property: definition
annotated source: anterior cerebral vein

posterior cerebral vein
type: Class
subclass of: cerebral vein
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2011-08-30T12:13:01Z
definition: Vein that drains the dorsal longitudinal vessel and the caudal portions of the venous capillary network of the medulla oblongata. The cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis lateralis.
id: XAO:0004159
database_cross_reference: ZFA:0005027
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: Vein that drains the dorsal longitudinal vessel and the caudal portions of the venous capillary network of the medulla oblongata. The cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis lateralis.
database_cross_reference: ZFA:0005027
annotated property: definition
annotated source: posterior cerebral vein

cerebral vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-30T12:16:59Z
definition: The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The veins are the anterior cerebral veins, posterior cerebral veins, and middle cerebral vein which cross dorsally between the bilateral vena capitis lateralis.
database_cross_reference: UBERON:0001663
id: XAO:0004160
created by: lab

Axiom
annotated target: The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The veins are the anterior cerebral veins, posterior cerebral veins, and middle cerebral vein which cross dorsally between the bilateral vena capitis lateralis.
database_cross_reference: UBERON:001663
annotated property: definition
annotated source: cerebral vein

middle cerebral vein
type: Class
subclass of: cerebral vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2011-08-30T12:23:07Z
definition: The middle cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis lateralis.
id: XAO:0004161
database_cross_reference: ZFA:0005010
created by: lab
has_exact_synonym: mid cerebral vein
has_exact_synonym: mid-cerebral vein

Axiom
database_cross_reference: PMID:12606281
annotated target: The middle cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis lateralis.
annotated property: definition
annotated source: middle cerebral vein

pulmonary artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: aortic arch 6
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
creation date: 2011-08-30T01:59:48Z
database_cross_reference: AAO:0010221
definition: The pulmonary arteries carry blood from heart to the lungs. They are the only arteries that carry deoxygenated blood. Develops from aortic arch 6 in Xenopus.
id: XAO:0004162
created by: lab

Axiom
annotated target: The pulmonary arteries carry blood from heart to the lungs. They are the only arteries that carry deoxygenated blood. Develops from aortic arch 6 in Xenopus.
database_cross_reference: UBERON:0002012
annotated property: definition
annotated source: pulmonary artery

angioblast
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2011-08-30T02:11:31Z
definition: A mesenchymal stem cell capable of developing into blood vessel endothelium.
database_cross_reference: CL:0000566
id: XAO:0004163
has_exact_synonym: angioblasts
created by: lab

Axiom
annotated target: A mesenchymal stem cell capable of developing into blood vessel endothelium.
database_cross_reference: CL:0000566
annotated property: definition
annotated source: angioblast

Axiom
annotated target: angioblasts
annotated source: angioblast
has_synonym_type: PLURAL
annotated property: has_exact_synonym

intersomitic vein
type: Class
subclass of: intersomitic vessel
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2011-08-30T02:26:59Z
definition: Veins that sprout from the posterior cardinal vein, growing dorsally between the somites, and will join, and drain the dorsal longitudinal anastomosing vessel.
id: XAO:0004164
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: Veins that sprout from the posterior cardinal vein, growing dorsally between the somites, and will join, and drain the dorsal longitudinal anastomosing vessel.
annotated property: definition
annotated source: intersomitic vein

intersomitic artery
type: Class
subclass of: intersomitic vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000059
creation date: 2011-08-30T02:29:23Z
definition: The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries.
database_cross_reference: UBERON:0006001
id: XAO:0004165
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries.
annotated property: definition
annotated source: intersomitic artery

left omphalomesenteric vein
type: Class
subclass of: omphalomesenteric vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
creation date: 2011-08-31T10:32:04Z
definition: In the trunk region, the subintestinal vein drains into the omphalomesenteric veins, which breaks up to merge with the vitelline network at NF stage 40.
id: XAO:0004166
created by: lab

Axiom
annotated target: In the trunk region, the subintestinal vein drains into the omphalomesenteric veins, which breaks up to merge with the vitelline network at NF stage 40.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: left omphalomesenteric vein

metencephalic artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: brain
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2011-08-31T10:38:54Z
definition: The artery that crosses the brain dorsally, and meets the metencephalic vein.
id: XAO:0004167
database_cross_reference: ZFA:0005084
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The artery that crosses the brain dorsally, and meets the metencephalic vein.
annotated property: definition
annotated source: metencephalic artery

metencephalic vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: brain
subclass of: Restriction
  on property: part of
  some values from: head vasculature
creation date: 2011-08-31T10:43:06Z
definition: The vein that crosses the brain dorsally, parallel with the mid-cerebral vein, and meets the metencephalic artery.
id: XAO:0004168
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The vein that crosses the brain dorsally, parallel with the mid-cerebral vein, and meets the metencephalic artery.
annotated property: definition
annotated source: metencephalic vein

ophthalmic vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: vena capitas medialis
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: head vasculature
creation date: 2011-08-31T11:03:57Z
definition: The dorsal branch/remnant of the vena capitis medialis, that drains blood from the eye. Together with the opthalmic artery, form a double ring encircling the eye and retina.
id: XAO:0004169
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The dorsal branch/remnant of the vena capitis medialis, that drains blood from the eye. Together with the opthalmic artery, form a double ring encircling the eye and retina.
annotated property: definition
annotated source: ophthalmic vein

vena capitas medialis
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
creation date: 2011-08-31T11:14:19Z
definition: One of the major dorsal head veins which drains into the anterior cardinal vein, the other being the vena capitas lateralis.
has_exact_synonym: VCM
id: XAO:0004170
created by: lab

Axiom
annotated target: One of the major dorsal head veins which drains into the anterior cardinal vein, the other being the vena capitas lateralis.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: vena capitas medialis

vena capitas lateralis
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2011-08-31T11:22:11Z
definition: One of the major dorsal head veins which drains into the anterior cardinal vein, the other being the vena capitas medialis.
id: XAO:0004171
created by: lab

Axiom
annotated target: One of the major dorsal head veins which drains into the anterior cardinal vein, the other being the vena capitas medialis.
database_cross_reference: PMID:12606281
annotated property: definition
annotated source: vena capitas lateralis

subintestinal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: tail vasculature
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000052
creation date: 2011-08-31T11:24:56Z
definition: The subintestinal vein is formed from and drains into the left omphalomesentric vein, and by NF stage 40, it is on the left side of the gut. It moves to the most ventral aspect of the gut during NFstage 41, and is on the right side of the gut by NF stage 43.
id: XAO:0004172
database_cross_reference: ZFA:0005035
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The subintestinal vein is formed from and drains into the left omphalomesentric vein, and by NF stage 40, it is on the left side of the gut. It moves to the most ventral aspect of the gut during NFstage 41, and is on the right side of the gut by NF stage 43.
annotated property: definition
annotated source: subintestinal vein

mesencephalic artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: midbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-31T12:02:13Z
definition: The major artery of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic vein.
database_cross_reference: UBERON:0001634
id: XAO:0004173
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The major artery of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic vein.
annotated property: definition
annotated source: mesencephalic artery

mesencephalic vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: part of
  some values from: midbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-31T12:04:02Z
definition: The major vein of the midbrain, which crosses the midbrain medially to meet it's partner the mesencephalic artery.
id: XAO:0004174
database_cross_reference: ZFA:0005092
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The major vein of the midbrain, which crosses the midbrain medially to meet it's partner the mesencephalic artery.
annotated property: definition
annotated source: mesencephalic vein

nasociliary artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-08-31T12:13:11Z
definition: The main artery of the olfactory region which arises from the cerebral artery at NF stage 41.
id: XAO:0004175
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The main artery of the olfactory region which arises from the cerebral artery at NF stage 41.
annotated property: definition
annotated source: nasociliary artery

choroidal vascular plexus
type: Class
subclass of: vascular plexus
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: head vasculature
creation date: 2011-08-31T12:26:08Z
has_related_synonym: <new synonym>
definition: A plexus of capillaries that is visible anteromedial to the eye. The choroid is the vascular layer of the eye, containing connective tissue, and lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract.
id: XAO:0004176
has_exact_synonym: capillary lamina of choroid or choriocapillaris
created by: lab
has_related_synonym: optic choroid vascular plexus

Axiom
annotated target: A plexus of capillaries that is visible anteromedial to the eye. The choroid is the vascular layer of the eye, containing connective tissue, and lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: choroidal vascular plexus

dorsal longitudinal anastomosing vessel
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2011-08-31T01:27:30Z
has_exact_synonym: DLAV
definition: Vessel into which intersomitic vessels enter in a regular pattern at each intersomitic junction. Posterior to the gut, the DLAV drains into the fused posterior cardinal vein by a minor right branch and a major left branch. By NF stage 36 the DLAV extends fully to the tip of the tail.
id: XAO:0004177
database_cross_reference: ZFA:0005025
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: Vessel into which intersomitic vessels enter in a regular pattern at each intersomitic junction. Posterior to the gut, the DLAV drains into the fused posterior cardinal vein by a minor right branch and a major left branch. By NF stage 36 the DLAV extends fully to the tip of the tail.
annotated property: definition
annotated source: dorsal longitudinal anastomosing vessel

dorsal longitudinal anastomosing vessel- left branch
type: Class
subclass of: dorsal longitudinal anastomosing vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
creation date: 2011-08-31T01:33:06Z
has_related_synonym: DLAV - left branch
definition: The major (left ) branch of the dorsal longitudinal anastomosing vessel (dlav), remains as the sole branch after the right branch breaks up at stage 44.
id: XAO:0004178
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The major (left ) branch of the dorsal longitudinal anastomosing vessel (dlav), remains as the sole branch after the right branch breaks up at stage 44.
annotated property: definition
annotated source: dorsal longitudinal anastomosing vessel- left branch

dorsal longitudinal anastomosing vessel- right branch
type: Class
subclass of: dorsal longitudinal anastomosing vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000057
creation date: 2011-08-31T01:38:24Z
has_exact_synonym: DLAV - right branch
definition: The minor (right) branch of the dorsal longitudinal anastomosing vessel (dlav), the right branch disappears during NF stage 44.
id: XAO:0004179
created by: lab

Axiom
database_cross_reference: PMID:12606281
annotated target: The minor (right) branch of the dorsal longitudinal anastomosing vessel (dlav), the right branch disappears during NF stage 44.
annotated property: definition
annotated source: dorsal longitudinal anastomosing vessel- right branch

olfactory bulb
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
subclass of: Restriction
  on property: part of
  some values from: telencephalon
subclass of: Restriction
  on property: part of
  some values from: olfactory system
creation date: 2011-08-31T02:08:00Z
definition: Part of the telencephalon, comprised of paired anterior outgrowths of either of the cerebral hemispheres in which the olfactory nerve exits. In Xenopus,the olfactory bulbs begin to fuse at NF stage 50, fusion is complete around NF stage 58. The cerebral vein loops around the olfactory bulb by NF stage 43.
database_cross_reference: UBERON:0002264
id: XAO:0004180
has_exact_synonym: bulbus olfactorius
created by: lab
has_related_synonym: olfactory lobe

Axiom
database_cross_reference: AAO:0010165
database_cross_reference: ISBN:0815318960
annotated target: Part of the telencephalon, comprised of paired anterior outgrowths of either of the cerebral hemispheres in which the olfactory nerve exits. In Xenopus,the olfactory bulbs begin to fuse at NF stage 50, fusion is complete around NF stage 58. The cerebral vein loops around the olfactory bulb by NF stage 43.
annotated property: definition
annotated source: olfactory bulb

cardiomyocyte
type: Class
subclass of: cell
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: myocardium
creation date: 2011-09-02T09:18:06Z
database_cross_reference: CL:0000193
definition: The cells that comprise cardiac muscle, specificially the myocardium.
id: XAO:0004181
has_exact_synonym: cardiac muscle cell
has_exact_synonym: cardiac muscle cells
has_related_synonym: cardiac myocytes
created by: lab

Axiom
annotated target: cardiac myocytes
annotated source: cardiomyocyte
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: cardiac muscle cells
annotated source: cardiomyocyte
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
database_cross_reference: CL:0000193
annotated target: The cells that comprise cardiac muscle, specificially the myocardium.
database_cross_reference: ZFA:0009316
annotated property: definition
annotated source: cardiomyocyte

pericardium
type: Class
subclass of: peritoneum
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
creation date: 2011-09-02T09:40:58Z
database_cross_reference: AAO:0010817
definition: The outer membrane/wall of the developing heart, surrounding the myocardium. Peritoneum that surrounds the heart.
id: XAO:0004182
created by: lab

Axiom
database_cross_reference: AAO:0010817
annotated target: The outer membrane/wall of the developing heart, surrounding the myocardium. Peritoneum that surrounds the heart.
annotated property: definition
annotated source: pericardium

pericardial muscle
type: Class
subclass of: muscle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: part of
  some values from: heart
creation date: 2011-09-02T09:46:21Z
definition: Muscle which is paired and runs anterio-posteriorly along the heart and is covered with epicardium.
id: XAO:0004183
database_cross_reference: ZFA:0001653
created by: lab

Axiom
annotated target: Muscle which is paired and runs anterio-posteriorly along the heart and is covered with epicardium.
database_cross_reference: ZFA:0001653
annotated property: definition
annotated source: pericardial muscle

pericardial roof
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: pericardium
creation date: 2011-09-02T10:01:41Z
definition: The dorsal region of the pericardium.
id: XAO:0004184
created by: lab

Axiom
database_cross_reference: PMID:18598690
annotated target: The dorsal region of the pericardium.
annotated property: definition
annotated source: pericardial roof

primary heart field
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000039
creation date: 2011-09-02T10:49:26Z
has_related_synonym: FHF
has_related_synonym: PHF
definition: The field of cardiac progenitor cells that form the heart tube in the embryonic heart.
database_cross_reference: UBERON:0004140
id: XAO:0004185
has_exact_synonym: first heart field
created by: lab

Axiom
database_cross_reference: PMID:18598690
database_cross_reference: PMID:20671188
annotated target: The field of cardiac progenitor cells that form the heart tube in the embryonic heart.
annotated property: definition
annotated source: primary heart field

secondary heart field
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000041
creation date: 2011-09-02T10:56:21Z
has_related_synonym: SHF
definition: The population of cells located in the splanchnic mesoderm that contribute to the formation of the spiral septum of the outflow tract of the embryonic heart, it is located anterior to the primary heart field.
id: XAO:0004186
created by: lab
has_exact_synonym: second heart field

Axiom
database_cross_reference: PMID:18598690
database_cross_reference: PMID:20671188
annotated target: The population of cells located in the splanchnic mesoderm that contribute to the formation of the spiral septum of the outflow tract of the embryonic heart, it is located anterior to the primary heart field.
annotated property: definition
annotated source: secondary heart field

anterior branchial crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: neural crest
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: develops from
  some values from: branchial crest
creation date: 2011-09-02T11:14:48Z
has_exact_synonym: ABC
definition: Branchial crest that is the 3rd neural crest stream and lays between hyoid crest and posterior branchial crest.
id: XAO:0004187
created by: lab

Axiom
annotated target: Branchial crest that is the 3rd neural crest stream and lays between hyoid crest and posterior branchial crest.
database_cross_reference: PMID:21490068
annotated property: definition
annotated source: anterior branchial crest

posterior branchial crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: part of
  some values from: neural crest
subclass of: Restriction
  on property: develops from
  some values from: branchial crest
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
creation date: 2011-09-02T11:18:11Z
definition: Branchial crest that is the most posterior of the five neural crest streams.
has_exact_synonym: PBC
id: XAO:0004188
created by: lab

Axiom
annotated target: Branchial crest that is the most posterior of the five neural crest streams.
database_cross_reference: PMID:21490068
annotated property: definition
annotated source: posterior branchial crest

endocardial cushion
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: heart
subclass of: Restriction
  on property: part of
  some values from: endocardium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000048
creation date: 2011-09-02T02:17:35Z
definition: The discrete swellings of cardiac jelly in the outflow tract and ventricular walls of the developing embryonic heart.
database_cross_reference: UBERON:0002062
id: XAO:0004189
has_related_synonym: cardiac cushion
created by: lab

Axiom
database_cross_reference: PMID:21490068
annotated target: The discrete swellings of cardiac jelly in the outflow tract and ventricular walls of the developing embryonic heart.
annotated property: definition
annotated source: endocardial cushion

cardiac neural crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: part of
  some values from: neural crest
creation date: 2011-09-02T02:35:20Z
definition: Neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to contribute to the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart where it contribures to connective tissue (septa) that separates the vessels of the heart. Cardiac neural crest develops into melanocytes, cartilage, connective tissue and neurons of some pharyngeal arches.
database_cross_reference: UBERON:0000095
id: XAO:0004190
created by: lab

Axiom
annotated target: Neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to contribute to the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart where it contribures to connective tissue (septa) that separates the vessels of the heart. Cardiac neural crest develops into melanocytes, cartilage, connective tissue and neurons of some pharyngeal arches.
database_cross_reference: WIKI:Cardiac_neural_crest_complex
annotated property: definition
annotated source: cardiac neural crest

vagal neural crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: part of
  some values from: neural crest
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
creation date: 2011-09-02T02:50:42Z
definition: One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the sacral neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. These cells, between the head and trunk, contribute post-cranially to the heart and gut, the chromatophores (pigment cells) of the epidermis, and the majority of the neurons and glial cells of the enteric nervous system. Both vagal and sacral neural crest cells contribute to the enteric nervous system in the hindgut.
database_cross_reference: UBERON:0005428
has_exact_synonym: VNC
id: XAO:0004191
created by: lab

Axiom
annotated target: One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the sacral neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. These cells, between the head and trunk, contribute post-cranially to the heart and gut, the chromatophores (pigment cells) of the epidermis, and the majority of the neurons and glial cells of the enteric nervous system. Both vagal and sacral neural crest cells contribute to the enteric nervous system in the hindgut.
database_cross_reference: PMID:9753687
database_cross_reference: XAO:CJZ
annotated property: definition
annotated source: vagal neural crest

sacral neural crest
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000046
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
subclass of: Restriction
  on property: part of
  some values from: neural crest
creation date: 2011-09-02T02:53:34Z
definition: One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the vagal neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. Sacral crest cells are associated with extrinsic nerve fibers of the hindgut and colon.
has_exact_synonym: SNC
id: XAO:0004192
created by: lab

Axiom
annotated target: One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the vagal neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. Sacral crest cells are associated with extrinsic nerve fibers of the hindgut and colon.
database_cross_reference: XAO:CJZ
annotated property: definition
annotated source: sacral neural crest

ossicle
type: Class
subclass of: skeletal element
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-09-13T09:36:09Z
definition: Skeletal element that is often isolated, small, and is usually ossified.
database_cross_reference: VSAO:0000132
id: XAO:0004193
created by: lab

Axiom
annotated target: Skeletal element that is often isolated, small, and is usually ossified.
database_cross_reference: VAO:0000132
annotated property: definition
annotated source: ossicle

appendicular ossicle
type: Class
subclass of: ossicle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-09-13T09:38:19Z
definition: Ossicle that is part of the appendicular skeleton.
database_cross_reference: VSAO:0000131
id: XAO:0004194
created by: lab

Axiom
annotated target: Ossicle that is part of the appendicular skeleton.
database_cross_reference: VAO:0000131
annotated property: definition
annotated source: appendicular ossicle

cellular bone tissue
type: Class
subclass of: mineralized bone tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-09-13T09:43:56Z
definition: Mineralized bone tissue that always includes non-terminally differentiated osteoblasts and osteocytes.
database_cross_reference: VSAO:0000118
id: XAO:0004195
created by: lab

Axiom
annotated target: Mineralized bone tissue that always includes non-terminally differentiated osteoblasts and osteocytes.
database_cross_reference: VAO:0000118
annotated property: definition
annotated source: cellular bone tissue

cementum
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
creation date: 2011-09-13T09:46:43Z
definition: Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument.
database_cross_reference: VSAO:0000062
id: XAO:0004196
has_exact_synonym: bone of attachment
created by: lab

Axiom
annotated target: Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument.
database_cross_reference: VAO:0000062
annotated property: definition
annotated source: cementum

elastic cartilage tissue
type: Class
subclass of: non-mineralized hyaline cartilage tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: chondrogenic condensation
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2011-09-13T09:48:42Z
definition: Cartilage tissue that is flexible and contains abundant elastic fibers.
database_cross_reference: VSAO:0000091
id: XAO:0004197
created by: lab

Axiom
annotated target: Cartilage tissue that is flexible and contains abundant elastic fibers.
database_cross_reference: VAO:0000091
annotated property: definition
annotated source: elastic cartilage tissue

enamel
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
subclass of: Restriction
  on property: develops from
  some values from: pre-enamel
creation date: 2011-09-13T09:51:23Z
definition: Skeletal tissue that consists of an avascular, noncollagenous, hypermineralized matrix that is deposited by ameloblasts that are excluded from the matrix. Enamel develops from organic pre-enamel tissue that is replaced by a largely inorganic matrix.
database_cross_reference: VSAO:0000065
id: XAO:0004198
has_exact_synonym: enamel tissue
created by: lab

Axiom
annotated target: Skeletal tissue that consists of an avascular, noncollagenous, hypermineralized matrix that is deposited by ameloblasts that are excluded from the matrix. Enamel develops from organic pre-enamel tissue that is replaced by a largely inorganic matrix.
database_cross_reference: VAO:0000065
annotated property: definition
annotated source: enamel

enameloid
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: develops from
  some values from: pre-enameloid
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
creation date: 2011-09-13T09:56:25Z
definition: Skeletal tissue that is hypermineralized and aprismatic and deposited by a combination of ameloblasts and odontoblasts that are excluded from the matrix. Enameloid develops from pre-enameloid tissue.
database_cross_reference: VSAO:0000113
id: XAO:0004199
has_exact_synonym: bitypic enamel
has_related_synonym: durodentine
has_exact_synonym: enameloid tissue
created by: lab
has_exact_synonym: vitrodentine

Axiom
annotated target: Skeletal tissue that is hypermineralized and aprismatic and deposited by a combination of ameloblasts and odontoblasts that are excluded from the matrix. Enameloid develops from pre-enameloid tissue.
database_cross_reference: VAO:0000113
annotated property: definition
annotated source: enameloid

non-mineralized chondroid tissue
type: Class
subclass of: skeletal tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
creation date: 2011-09-13T09:59:02Z
definition: Chondroid tissue that is not mineralized.
database_cross_reference: VSAO:0000077
id: XAO:0004200
created by: lab

Axiom
annotated target: Chondroid tissue that is not mineralized.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: non-mineralized chondroid tissue

odontode tissue
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
subclass of: Restriction
  on property: develops from
  some values from: pre-dentine
creation date: 2011-09-13T10:00:35Z
definition: Skeletal tissue that is avascular tubular mineralized matrix, primarily made of dentine that is deposited by odontoblasts that are excluded from the matrix; develops from pre-dentine tissue.
database_cross_reference: VSAO:0000123
id: XAO:0004201
has_related_synonym: dental tissue
created by: lab

Axiom
annotated target: Skeletal tissue that is avascular tubular mineralized matrix, primarily made of dentine that is deposited by odontoblasts that are excluded from the matrix; develops from pre-dentine tissue.
database_cross_reference: VAO:0000123
annotated property: definition
annotated source: odontode tissue

pre-enamel
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
creation date: 2011-09-13T10:08:54Z
definition: Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix.
database_cross_reference: VSAO:0000066
id: XAO:0004202
created by: lab
has_exact_synonym: pre-enamel tissue
has_exact_synonym: preenamel tissue

Axiom
annotated target: Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix.
database_cross_reference: VAO:0000066
annotated property: definition
annotated source: pre-enamel

pre-enameloid
type: Class
subclass of: odontoid tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000072
creation date: 2011-09-13T10:15:16Z
definition: Odontoid tissue that is avascular non-mineralized matrix that is deposited by odontoblasts and ameloblasts that are excluded from the matrix.
database_cross_reference: VSAO:0000114
id: XAO:0004203
created by: lab
has_exact_synonym: non-mineralized enameloid tissue

Axiom
annotated target: Odontoid tissue that is avascular non-mineralized matrix that is deposited by odontoblasts and ameloblasts that are excluded from the matrix.
database_cross_reference: VAO:0000114
annotated property: definition
annotated source: pre-enameloid

sesamoid
type: Class
subclass of: ossicle
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000074
creation date: 2011-09-13T10:23:39Z
definition: Replacement element; an ossicle; often an endochondral replacement element that has cartilage and bone states that develops in dense regular connective tissue (e.g., tendons and ligaments).
database_cross_reference: VSAO:0000137
id: XAO:0004204
created by: lab

Axiom
annotated target: Replacement element; an ossicle; often an endochondral replacement element that has cartilage and bone states that develops in dense regular connective tissue (e.g., tendons and ligaments).
database_cross_reference: VAO:0000137
annotated property: definition
annotated source: sesamoid

gall bladder primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000052
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
creation date: 2011-09-13T01:15:58Z
definition: A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops.
database_cross_reference: UBERON:0006242
id: XAO:0004205
created by: lab

Axiom
annotated target: A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: gall bladder primordium

anterior placodal area
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: preplacodal ectoderm
creation date: 2011-09-13T01:29:48Z
has_exact_synonym: APA
definition: One of the 2 subregions of the pre-placodal ectoderm, which lies abutting and anterior to the neural plate.
id: XAO:0004206
created by: lab

Axiom
database_cross_reference: ISBN:0878933840
annotated target: One of the 2 subregions of the pre-placodal ectoderm, which lies abutting and anterior to the neural plate.
annotated property: definition
annotated source: anterior placodal area

posterior placodal area
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000044
subclass of: Restriction
  on property: part of
  some values from: preplacodal ectoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
creation date: 2011-09-13T01:40:58Z
definition: One of the 2 subregions of the pre-placodal ectoderm, which lies abutting and lateral to the neural crest.
has_exact_synonym: PPA
id: XAO:0004207
created by: lab

Axiom
database_cross_reference: ISBN:0878933840
annotated target: One of the 2 subregions of the pre-placodal ectoderm, which lies abutting and lateral to the neural crest.
annotated property: definition
annotated source: posterior placodal area

adenohypophyseal placode
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: non-neural ectoderm
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
creation date: 2011-09-13T01:47:17Z
definition: The small pre-placodal ectoderm area that develops at the midline of the anterior neural ridge, abutting the anterior neural plate, and invagintes to form Rathke's pouch, which in turn forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary.
id: XAO:0004208
created by: lab
has_exact_synonym: pituitary placode

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The small pre-placodal ectoderm area that develops at the midline of the anterior neural ridge, abutting the anterior neural plate, and invagintes to form Rathke's pouch, which in turn forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary.
annotated property: definition
annotated source: adenohypophyseal placode

anterior neural ridge
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000038
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000032
creation date: 2011-09-13T02:26:18Z
has_exact_synonym: ANR
definition: The region that delineates the rostral boundary of the neural plate in the neural stage embryo, and is devoid of neural crest cells. It gives rise to the pre-placodal region, some elements of the forebrain, and the anterior lobe of the pituitary gland.
id: XAO:0004209
created by: lab

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The region that delineates the rostral boundary of the neural plate in the neural stage embryo, and is devoid of neural crest cells. It gives rise to the pre-placodal region, some elements of the forebrain, and the anterior lobe of the pituitary gland.
annotated property: definition
annotated source: anterior neural ridge

infundibulum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: diencephalon
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-09-13T02:33:45Z
definition: The region of the diencephalon above Rathke's pouch, and forms the posterior lobe of the pituitary.
id: XAO:0004210
database_cross_reference: ZFA:0001199
has_exact_synonym: hypophysial stalk
has_exact_synonym: infundibulum of hypothalamus
created by: lab
has_exact_synonym: pituitary stalk

Axiom
annotated target: The region of the diencephalon above Rathke's pouch, and forms the posterior lobe of the pituitary.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: infundibulum

facial epibranchial placode
type: Class
subclass of: epibranchial placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
creation date: 2011-09-14T09:21:23Z
definition: The most anterior of the epibranchial placodes, associated with the 1st pharyngeal cleft and it contributes to the distal ganglia of cranial nerve VII (facial nerve).
id: XAO:0004211
has_exact_synonym: geniculate placode
created by: lab

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The most anterior of the epibranchial placodes, associated with the 1st pharyngeal cleft and it contributes to the distal ganglia of cranial nerve VII (facial nerve).
annotated property: definition
annotated source: facial epibranchial placode

glossopharyngeal epibranchial placode
type: Class
subclass of: epibranchial placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
creation date: 2011-09-14T09:25:28Z
definition: The central of the three epibranchial placodes, associated with the 2nd pharyngeal cleft and it contributes to the distal ganglia of cranial nerve XI (glossopharyngeal nerve).
id: XAO:0004212
created by: lab
has_exact_synonym: petrosal placode

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The central of the three epibranchial placodes, associated with the 2nd pharyngeal cleft and it contributes to the distal ganglia of cranial nerve XI (glossopharyngeal nerve).
annotated property: definition
annotated source: glossopharyngeal epibranchial placode

vagal epibranchial placode
type: Class
subclass of: epibranchial placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000050
creation date: 2011-09-14T09:36:07Z
definition: The most posterior of the epibranchial placodes, in Xenopus in 3 distinct zones, associated with the 3rd -6th pharyngeal clefts, and contributing to the facial, lateral line and glossopharyngeal ganglion.
id: XAO:0004213
created by: lab
has_exact_synonym: nodose placode
has_exact_synonym: nodose placodes
has_exact_synonym: vagal epibranchial placodes

Axiom
annotated target: nodose placodes
annotated source: vagal epibranchial placode
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
annotated target: vagal epibranchial placodes
annotated source: vagal epibranchial placode
has_synonym_type: PLURAL
annotated property: has_exact_synonym

Axiom
database_cross_reference: ISBN:0878933840
annotated target: The most posterior of the epibranchial placodes, in Xenopus in 3 distinct zones, associated with the 3rd -6th pharyngeal clefts, and contributing to the facial, lateral line and glossopharyngeal ganglion.
annotated property: definition
annotated source: vagal epibranchial placode

cranial nerve XI
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
creation date: 2011-09-14T10:03:25Z
definition: A small motor nerve which emerges from the lateral wall of the medulla with the roots of the vagus nerve, and innervates a single pectoral suspensory muscle, the m.cucullaris.
id: XAO:0004214
has_exact_synonym: accessory nerve
created by: lab

Axiom
annotated target: A small motor nerve which emerges from the lateral wall of the medulla with the roots of the vagus nerve, and innervates a single pectoral suspensory muscle, the m.cucullaris.
database_cross_reference: ISBN:080184780X
annotated property: definition
annotated source: cranial nerve XI

cranial nerve XII
type: Class
subclass of: cranial nerve
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2011-09-14T10:07:12Z
definition: This nerve leads to the muscles of the tongue, and has both sensory and motor functions.
id: XAO:0004215
has_exact_synonym: hypoglossal nerve
created by: lab

Axiom
database_cross_reference: ISBN:080184780X
annotated target: This nerve leads to the muscles of the tongue, and has both sensory and motor functions.
annotated property: definition
annotated source: cranial nerve XII

glomeral nexus
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000066
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
subclass of: Restriction
  on property: develops from
  some values from: glomus
subclass of: Restriction
  on property: part of
  some values from: glomus
creation date: 2011-09-14T10:38:02Z
definition: The narrow bridge that links the two glomera of the pronephric kidney.
id: XAO:0004216
created by: lab

Axiom
annotated target: The narrow bridge that links the two glomera of the pronephric kidney.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: glomeral nexus

motor neuron
type: Class
subclass of: neuron
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2012-01-27T09:25:00Z
definition: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
database_cross_reference: CL:0000100
id: XAO:0004217
created by: eriks
has_exact_synonym: motoneuron

Axiom
annotated target: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
database_cross_reference: CL:0000100
annotated property: definition
annotated source: motor neuron

palatoquadrate
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: mandibular arch
subclass of: Restriction
  on property: develops from
  some values from: mandibular crest
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000040
database_cross_reference: AAO:0000379
definition: The dorsal component of the mandibular arch, the ventral one being Meckel's cartilage. Together with the ceratohyal and connecting musculature, it is responsible for the ventilation and irrigation of the filter apparatus.
id: XAO:0004218
created by: eriks

Axiom
annotated target: The dorsal component of the mandibular arch, the ventral one being Meckel's cartilage. Together with the ceratohyal and connecting musculature, it is responsible for the ventilation and irrigation of the filter apparatus.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: palatoquadrate

ceratohyal
type: Class
subclass of: cartilaginous element
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: hyoid arch
database_cross_reference: AAO:0000666
definition: Cartilaginous element that, together with the palatoquadrate and connecting musculature, is responsible for the ventilation and irrigation of the of the filter apparatus.
id: XAO:0004219
has_exact_synonym: ch
created by: eriks

Axiom
annotated target: Cartilaginous element that, together with the palatoquadrate and connecting musculature, is responsible for the ventilation and irrigation of the of the filter apparatus.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: ceratohyal

anteroventral lateral line placode
type: Class
subclass of: lateral line placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
creation date: 2012-01-27T09:32:47Z
definition: Lateral line placode that gives rise to the anteroventral lateral line nerve.
id: XAO:0004220
created by: eriks

Axiom
annotated target: Lateral line placode that gives rise to the anteroventral lateral line nerve.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: anteroventral lateral line placode

anterior lateral line placode
type: Class
subclass of: lateral line placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Lateral line placode that gives rise to the anterior lateral line nerve.
id: XAO:0004221
created by: eriks
has_related_synonym: pre-auditory lateral line placode

Axiom
annotated target: Lateral line placode that gives rise to the anterior lateral line nerve.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: anterior lateral line placode

middle lateral line placode
type: Class
subclass of: lateral line placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Lateral line placode that gives rise to the middle lateral line nerve.
id: XAO:0004222
created by: eriks
has_related_synonym: intermediate lateral line placode

Axiom
annotated target: Lateral line placode that gives rise to the middle lateral line nerve.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: middle lateral line placode

posterior lateral line placode
type: Class
subclass of: lateral line placode
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
definition: Lateral line placode that gives rise to the posterior lateral line nerve.
id: XAO:0004223
created by: eriks
has_related_synonym: vagus lateral line placode

Axiom
annotated target: Lateral line placode that gives rise to the posterior lateral line nerve.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: posterior lateral line placode

transporting epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Type of epithelium that facilitates the transcellular transport of solutes. This transport can either be absorption, transport from lumen (apical membrane surface) to blood; or secretion, transport from blood (basolateral membrane surface) to lumen.
id: XAO:0004224
created by: eriks
has_related_synonym: transporting epithelia

Axiom
annotated target: transporting epithelia
annotated source: transporting epithelium
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Type of epithelium that facilitates the transcellular transport of solutes. This transport can either be absorption, transport from lumen (apical membrane surface) to blood; or secretion, transport from blood (basolateral membrane surface) to lumen.
database_cross_reference: http://en.wikipedia.org/wiki/Transcellular_transport
annotated property: definition
annotated source: transporting epithelium

non-ciliated epithelial cell
type: Class
subclass of: epithelial cell
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000020
subclass of: Restriction
  on property: part of
  some values from: epithelium
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
definition: Type of cell of the epidermis lacking cilia, which separate and space the ciliated epidermal cells.
id: XAO:0004225
created by: eriks
has_related_synonym: intercalating non-ciliated cell
has_related_synonym: non-ciliated epithelial cells

Axiom
database_cross_reference: PMID:16728476
annotated target: Type of cell of the epidermis lacking cilia, which separate and space the ciliated epidermal cells.
annotated property: definition
annotated source: non-ciliated epithelial cell

Axiom
annotated target: non-ciliated epithelial cells
annotated source: non-ciliated epithelial cell
has_synonym_type: PLURAL
annotated property: has_related_synonym

ventral tegmentum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
subclass of: Restriction
  on property: part of
  some values from: midbrain
subclass of: Restriction
  on property: develops from
  some values from: neural plate
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Region of the mesencephalon that arises from a small area of the neural plate, spanning the midline immediately adjacent, and being slightly posterior to the dorsal tegmentum area.
database_cross_reference: UBERON:0002691
id: XAO:0004226
created by: eriks
has_related_synonym: tegmentum ventrale
has_related_synonym: ventral brain stem

Axiom
database_cross_reference: PMID:2351962
annotated target: Region of the mesencephalon that arises from a small area of the neural plate, spanning the midline immediately adjacent, and being slightly posterior to the dorsal tegmentum area.
annotated property: definition
annotated source: ventral tegmentum

dorsal tegmentum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: neural plate
subclass of: Restriction
  on property: part of
  some values from: midbrain
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
definition: Region of the mesencephalon that arises from a small area of the neural plate immediately adjacent and slightly anterior to the ventral tegmentum area.
id: XAO:0004227
has_related_synonym: dorsal brain stem
created by: eriks
has_related_synonym: tegmentum dorsale

Axiom
database_cross_reference: PMID:2351962
annotated target: Region of the mesencephalon that arises from a small area of the neural plate immediately adjacent and slightly anterior to the ventral tegmentum area.
annotated property: definition
annotated source: dorsal tegmentum

lateral abdominal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
creation date: 2012-01-27T09:37:16Z
definition: Laterally located vein that drains the ventral abdominal wall.
id: XAO:0004228
created by: eriks

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Laterally located vein that drains the ventral abdominal wall.
annotated property: definition
annotated source: lateral abdominal vein

fin crest
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: part of
  some values from: epidermis
subclass of: Restriction
  on property: develops from
  some values from: inner fin
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000058
subclass of: Restriction
  on property: part of
  some values from: tail
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000042
definition: The thin epidermis extension of the inner fin visible in the mid trunk region of the inner fin at NF stage 27, and extending posteriorly and then ventrally, ending just before the proctodeum. The fin is more homogeneous in NF stage 46 tadpoles, and the inner fin and fin crest are no longer discrete.
id: XAO:0004229
created by: eriks

Axiom
annotated target: The thin epidermis extension of the inner fin visible in the mid trunk region of the inner fin at NF stage 27, and extending posteriorly and then ventrally, ending just before the proctodeum. The fin is more homogeneous in NF stage 46 tadpoles, and the inner fin and fin crest are no longer discrete.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: fin crest

anterior hypothalamus
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: hypothalamus
creation date: 2012-01-27T09:51:09Z
definition: Anterior part of the hypothalamus, given rise by the midanterior neural ridge along with the chiasmatic ridge during forebrain morphogenesis.
id: XAO:0004230
created by: eriks

Axiom
annotated target: Anterior part of the hypothalamus, given rise by the midanterior neural ridge along with the chiasmatic ridge during forebrain morphogenesis.
database_cross_reference: PMID:8537821
annotated property: definition
annotated source: anterior hypothalamus

barbel
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000056
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000073
definition: A single long structure at each corner of the mouth that has muscle fibers attached to an internal cartilaginous support and that is mobile.
id: XAO:0004231
created by: eriks

Axiom
annotated target: A single long structure at each corner of the mouth that has muscle fibers attached to an internal cartilaginous support and that is mobile.
database_cross_reference: ISBN:0226557626
annotated property: definition
annotated source: barbel

spiracle
type: Class
subclass of: surface structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: The exit for respiratory water in the tadpole.
id: XAO:0004232
created by: eriks

Axiom
database_cross_reference: ISBN:0226557626
annotated target: The exit for respiratory water in the tadpole.
annotated property: definition
annotated source: spiracle

truncus arteriosus
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000046
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A cranial continuation of the bulbis cordis that contains two lateral branches and divides into the carotid arch, systemic arch, and pulmocutaneous arch.
database_cross_reference: UBERON:0002061
id: XAO:0004233
created by: eriks

Axiom
annotated target: A cranial continuation of the bulbis cordis that contains two lateral branches and divides into the carotid arch, systemic arch, and pulmocutaneous arch.
database_cross_reference: ISBN:0801836018
annotated property: definition
annotated source: truncus arteriosus

bulbous arteriosis
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: cardiovascular system
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000044
definition: Multi-tissue structure through which the blood exits the heart. It is a chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches.
id: XAO:0004234
created by: eriks

Axiom
annotated target: Multi-tissue structure through which the blood exits the heart. It is a chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches.
database_cross_reference: ZFA:0000173
annotated property: definition
annotated source: bulbous arteriosis

manicotto glandulare
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: alimentary system
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: The larval stomach.
id: XAO:0004235
created by: eriks

Axiom
database_cross_reference: ISBN:0226893340
annotated target: The larval stomach.
annotated property: definition
annotated source: manicotto glandulare

posterior hypothalamus
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: hypothalamus
creation date: 2012-01-27T09:51:49Z
definition: Posterior part of the hypothalamus, given rise by the midanterior neural plate during forebrain morphogenesis.
id: XAO:0004236
created by: eriks

Axiom
database_cross_reference: PMID:8537821
annotated target: Posterior part of the hypothalamus, given rise by the midanterior neural plate during forebrain morphogenesis.
annotated property: definition
annotated source: posterior hypothalamus

lateral ganglionic eminence
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: part of
  some values from: telencephalon
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2012-01-27T09:59:19Z
has_related_synonym: LGE
definition: Transitory brain structure laterally located in the ventral part of the telencephalon, where it forms bulges in the ventricles.
database_cross_reference: UBERON:0004025
id: XAO:0004237
created by: eriks

Axiom
annotated target: Transitory brain structure laterally located in the ventral part of the telencephalon, where it forms bulges in the ventricles.
database_cross_reference: http://en.wikipedia.org/wiki/Ganglionic_eminence
annotated property: definition
annotated source: lateral ganglionic eminence

femur rudiment
type: Class
subclass of: cartilaginous element
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000063
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000067
definition: A cartilaginous element that is the primordium or commencement of a femur.
id: XAO:0004238
created by: eriks

Axiom
annotated target: A cartilaginous element that is the primordium or commencement of a femur.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: femur rudiment

hind digit 1
type: Class
subclass of: hind digit
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
definition: The 1st digit of the foot.
database_cross_reference: UBERON:0003631
id: XAO:0004239
created by: eriks
has_related_synonym: hallux
has_exact_synonym: toe 1
has_exact_synonym: toe I

Axiom
annotated target: The 1st digit of the foot.
database_cross_reference: UBERON:0003631
annotated property: definition
annotated source: hind digit 1

branchial vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000078
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
definition: Type of vein that drains the gill region and which passes backwards lateral to the gill chambers and opens into the pronephric sinus.
id: XAO:0004240
created by: eriks

Axiom
database_cross_reference: ISBN:0815318960
annotated target: Type of vein that drains the gill region and which passes backwards lateral to the gill chambers and opens into the pronephric sinus.
annotated property: definition
annotated source: branchial vein

ischiadic vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000062
definition: A vein of the hind limb, first visible in the developing hind limb bud at c. NF stage 50 when it enters the ventral commissural vessel.
id: XAO:0004241
created by: eriks

Axiom
annotated target: A vein of the hind limb, first visible in the developing hind limb bud at c. NF stage 50 when it enters the ventral commissural vessel.
database_cross_reference: ISBN:0815318960
annotated property: definition
annotated source: ischiadic vein

ischiadic artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
definition: The accompanying artery of ischiadic nerve.
id: XAO:0004242
created by: eriks

Axiom
annotated target: The accompanying artery of ischiadic nerve.
database_cross_reference: http://en.wikipedia.org/wiki/Accompanying_artery_of_ischiadic_nerve
annotated property: definition
annotated source: ischiadic artery

femoral vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004296
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000063
database_cross_reference: AAO:0010237
definition: Either of the primary veins in the hindlimbs which collect blood from the hindlimb region.
id: XAO:0004243
created by: eriks
has_related_synonym: vena femoralis

Axiom
database_cross_reference: AAO:0010237
annotated target: Either of the primary veins in the hindlimbs which collect blood from the hindlimb region.
annotated property: definition
annotated source: femoral vein

mandibular artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010496
definition: Part of the lateral pretrosal artery which supplies blood to the roof of the mouth.
id: XAO:0004244
created by: eriks

Axiom
database_cross_reference: AAO:0010496
annotated target: Part of the lateral pretrosal artery which supplies blood to the roof of the mouth.
annotated property: definition
annotated source: mandibular artery

maxillary artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
definition: A type of artery that supplies the deep structures of the facial region. It branches from the external carotid artery.
database_cross_reference: UBERON:0001616
id: XAO:0004245
created by: eriks

Axiom
annotated target: A type of artery that supplies the deep structures of the facial region. It branches from the external carotid artery.
database_cross_reference: http://en.wikipedia.org/wiki/Maxillary_artery
annotated property: definition
annotated source: maxillary artery

rhombomere R7
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2012-01-27T10:01:06Z
definition: The 7th segment of the developing hindbrain.
database_cross_reference: UBERON:0005523
id: XAO:0004246
created by: eriks
has_exact_synonym: r7
has_exact_synonym: rhombomere 7

Axiom
annotated target: The 7th segment of the developing hindbrain.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: rhombomere R7

vertebral artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: ends during
  some values from: death
definition: A major artery of the neck that branches from the subclavian arteries and merge to form the single midline basilar artery.
database_cross_reference: UBERON:0001535
id: XAO:0004247
created by: eriks

Axiom
annotated target: A major artery of the neck that branches from the subclavian arteries and merge to form the single midline basilar artery.
database_cross_reference: http://en.wikipedia.org/wiki/Vertebral_artery
annotated property: definition
annotated source: vertebral artery

epigastric artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
definition: Artery that supplies the anterior wall of the abdomen.
database_cross_reference: UBERON:0006349
id: XAO:0004248
created by: eriks

Axiom
annotated target: Artery that supplies the anterior wall of the abdomen.
database_cross_reference: http://medical-dictionary.thefreedictionary.com/epigastric+artery
annotated property: definition
annotated source: epigastric artery

renal artery
type: Class
subclass of: artery
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
subclass of: Restriction
  on property: part of
  some values from: urogenital system
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
database_cross_reference: AAO:0010223
definition: Artery which supplies blood via branches to the gonads, oviducts, and kidneys.
id: XAO:0004249
created by: eriks
has_related_synonym: interrenal artery

Axiom
database_cross_reference: AAO:0010223
annotated target: Artery which supplies blood via branches to the gonads, oviducts, and kidneys.
annotated property: definition
annotated source: renal artery

facial vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000070
subclass of: Restriction
  on property: part of
  some values from: head vasculature
subclass of: Restriction
  on property: ends during
  some values from: death
database_cross_reference: AAO:0010513
definition: Vein which collects blood from muscles of the head and drains into the external jugular vein.
id: XAO:0004250
created by: eriks

Axiom
database_cross_reference: AAO:0010513
annotated target: Vein which collects blood from muscles of the head and drains into the external jugular vein.
annotated property: definition
annotated source: facial vein

cutaneous magnus
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000057
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
definition: Vein that comes from the skin of the trunk.
id: XAO:0004251
created by: eriks

Axiom
annotated target: Vein that comes from the skin of the trunk.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: cutaneous magnus

cutaneous femoral vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004296
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
definition: Vein that comes from the subcutaneous tissue of the hindlimb stylopod.
id: XAO:0004252
created by: eriks

Axiom
annotated target: Vein that comes from the subcutaneous tissue of the hindlimb stylopod.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: cutaneous femoral vein

postcaval vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
database_cross_reference: AAO:0010506
definition: One of three major veins which enter the sinus venosus.
id: XAO:0004253
created by: eriks

Axiom
database_cross_reference: AAO:0010506
annotated target: One of three major veins which enter the sinus venosus.
annotated property: definition
annotated source: postcaval vein

subclavian vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000060
creation date: 2012-01-28T05:08:21Z
database_cross_reference: AAO:0010510
definition: Vein which collects blood from the forelimb via the branchial veins and from the muscles and skin of the trunk via the anterior epigastric and lateral veins.
id: XAO:0004254
created by: eriks

Axiom
database_cross_reference: AAO:0010510
annotated target: Vein which collects blood from the forelimb via the branchial veins and from the muscles and skin of the trunk via the anterior epigastric and lateral veins.
annotated property: definition
annotated source: subclavian vein

lateral vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
database_cross_reference: AAO:0010515
definition: Either of the veins which collect blood from the trunk and skin and drain into the subclavian vein.
id: XAO:0004255
created by: eriks

Axiom
database_cross_reference: AAO:0010515
annotated target: Either of the veins which collect blood from the trunk and skin and drain into the subclavian vein.
annotated property: definition
annotated source: lateral vein

ventral abdominal vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000054
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: part of
  some values from: XAO_0004423
definition: A vein formed by the combination of veins in the pelvic region which collects blood from the liver, stomach, intestines, and gall bladder.
database_cross_reference: AAO:0010517
id: XAO:0004256
created by: eriks

Axiom
annotated target: A vein formed by the combination of veins in the pelvic region which collects blood from the liver, stomach, intestines, and gall bladder.
database_cross_reference: AAO:0010517
annotated property: definition
annotated source: ventral abdominal vein

Jacobson's vein
type: Class
subclass of: vein
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000050
database_cross_reference: AAO:0010519
definition: Vein which drains Jacobson's organ.
id: XAO:0004257
created by: eriks

Axiom
annotated target: Vein which drains Jacobson's organ.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: Jacobson's vein

subpallium
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: part of
  some values from: telencephalon
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Structure that comprises the base region of the telencephalon.
database_cross_reference: UBERON:0000204
id: XAO:0004258
created by: eriks

Axiom
annotated target: Structure that comprises the base region of the telencephalon.
database_cross_reference: UBERON:0000204
annotated property: definition
annotated source: subpallium

medial ganglionic eminence
type: Class
subclass of: embryonic structure
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: part of
  some values from: telencephalon
has_exact_synonym: MGE
definition: Transitory brain structure medially located in the ventral part of the telencephalon, where it forms bulges in the ventricles.
database_cross_reference: UBERON:0004024
id: XAO:0004259
created by: eriks

Axiom
annotated target: Transitory brain structure medially located in the ventral part of the telencephalon, where it forms bulges in the ventricles.
database_cross_reference: http://en.wikipedia.org/wiki/Ganglionic_eminence
annotated property: definition
annotated source: medial ganglionic eminence

pharyngeal pouch
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000051
subclass of: Restriction
  on property: part of
  some values from: pharyngeal region
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000043
subclass of: Restriction
  on property: develops from
  some values from: XAO_0004463
definition: Any of the outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits.
database_cross_reference: UBERON:0004117
id: XAO:0004260
created by: eriks
has_related_synonym: pharyngeal pouches

Axiom
annotated target: pharyngeal pouches
annotated source: pharyngeal pouch
has_synonym_type: PLURAL
annotated property: has_related_synonym

Axiom
annotated target: Any of the outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits.
database_cross_reference: TAO:0001106
annotated property: definition
annotated source: pharyngeal pouch

pharyngeal region
type: Class
subclass of: anatomical region
subclass of: Restriction
  on property: part of
  some values from: head
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
definition: Region encompassing the oral end of the alimentary canal.
database_cross_reference: UBERON:0009145
id: XAO:0004261
created by: eriks

Axiom
annotated target: Region encompassing the oral end of the alimentary canal.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: pharyngeal region

ventral caudal lymphatic vessel
type: Class
subclass of: lymph vessel
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000049
definition: Lymphatic vessel located in the posterior ventral region of the trunk, ventral to the posterior cardinal vein.
has_exact_synonym: VCLV
id: XAO:0004262
created by: eriks

Axiom
annotated target: Lymphatic vessel located in the posterior ventral region of the trunk, ventral to the posterior cardinal vein.
database_cross_reference: PMID:9048122465
annotated property: definition
annotated source: ventral caudal lymphatic vessel

stylopod
type: Class
subclass of: XAO_0004294
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
definition: Limb segment that is the proximal part of the limb.
database_cross_reference: UBERON:0002472
id: XAO:0004263
created by: eriks

Axiom
annotated target: Limb segment that is the proximal part of the limb.
database_cross_reference: UBERON:0002472
annotated property: definition
annotated source: stylopod

zeugopod
type: Class
subclass of: XAO_0004294
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
definition: Limb segment that is the middle part of the limb.
database_cross_reference: UBERON:0002471
id: XAO:0004264
created by: eriks

Axiom
annotated target: Limb segment that is the middle part of the limb.
database_cross_reference: UBERON:0002471
annotated property: definition
annotated source: zeugopod

autopod
type: Class
subclass of: XAO_0004294
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000067
subclass of: Restriction
  on property: ends during
  some values from: death
definition: Limb segment that is the terminal part of the limb.
database_cross_reference: UBERON:0002470
id: XAO:0004265
created by: eriks

Axiom
annotated target: Limb segment that is the terminal part of the limb.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: autopod

rhombomere R8
type: Class
subclass of: rhombomere
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
creation date: 2012-01-27T10:01:21Z
definition: The 8th and most posterior segment of the developing hindbrain.
database_cross_reference: UBERON:0005527
id: XAO:0004266
created by: eriks
has_exact_synonym: r8
has_exact_synonym: rhombomere 8

Axiom
annotated target: The 8th and most posterior segment of the developing hindbrain.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: rhombomere R8

interneuron
type: Class
subclass of: neuron
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000025
creation date: 2012-01-27T10:24:56Z
definition: A multipolar neuron that connects afferent neurons and efferent neurons in neural pathways. They are found within the central nervous system and enteric nervous system.
database_cross_reference: CL:0000099
id: XAO:0004267
created by: eriks

Axiom
annotated target: A multipolar neuron that connects afferent neurons and efferent neurons in neural pathways. They are found within the central nervous system and enteric nervous system.
database_cross_reference: WIKI:Interneuron
annotated property: definition
annotated source: interneuron

posterior lateral line
type: Class
subclass of: lateral line
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000053
definition: A lateral line that extends from the ear in a posterior-ventral direction.
id: XAO:0004268
created by: eriks

Axiom
annotated target: A lateral line that extends from the ear in a posterior-ventral direction.
database_cross_reference: PMID:2652193
annotated property: definition
annotated source: posterior lateral line

anterodorsal lateral line placode
type: Class
subclass of: lateral line placode
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000048
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000053
definition: Lateral line placode that gives rise to the anterodorsal lateral line nerve.
id: XAO:0004269
created by: eriks

Axiom
annotated target: Lateral line placode that gives rise to the anterodorsal lateral line nerve.
database_cross_reference: XAO:EJS
annotated property: definition
annotated source: anterodorsal lateral line placode

hepato-pancreatic progenitor cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: ends during
  some values from: XAO_1000056
subclass of: Restriction
  on property: develops from
  some values from: endoderm
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000036
subclass of: Restriction
  on property: part of
  some values from: foregut
definition: Any of a field of cells in the posterior section of the foregut that will give rise to the liver bud and dorsal and ventral pancreatic buds.
id: XAO:0004270
created by: eriks
has_related_synonym: hepato-pancreatic progenitor cells

Axiom
annotated target: Any of a field of cells in the posterior section of the foregut that will give rise to the liver bud and dorsal and ventral pancreatic buds.
database_cross_reference: XAO:curator
annotated property: definition
annotated source: hepato-pancreatic progenitor cell

Axiom
annotated target: hepato-pancreatic progenitor cells
annotated source: hepato-pancreatic progenitor cell
has_synonym_type: PLURAL
annotated property: has_related_synonym

midbrain tegmentum
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: ends during
  some values from: death
subclass of: Restriction
  on property: develops from
  some values from: ventral tegmentum
subclass of: Restriction
  on property: part of
  some values from: midbrain
subclass of: Restriction
  on property: develops from
  some values from: dorsal tegmentum
subclass of: Restriction
  on property: starts during
  some values from: XAO_1000038
creation date: 2012-01-28T06:06:15Z
definition: Multi-tissue structure that is the ventral part of the midbrain.
database_cross_reference: UBERON:0001943
id: XAO:0004271
created by: eriks

Axiom
annotated target: Multi-tissue structure that is the ventral part of the midbrain.
database_cross_reference: ZFA:0000160
annotated property: definition
annotated source: midbrain tegmentum

migrating neuroblast
type: Class
subclass of: cell
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
creation date: 2012-02-08T12:22:41Z
definition: Any of the neuronal precursor cells that are isolated and scattered throughout the anterior ventro-lateral region of the embryo, generally in a punctate pattern, immediately below the ectoderm.
id: XAO:0004272
created by: eriks